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Research Articles

The Finnish Adoptive Family Study of Schizophrenia: differences in somatic diseases and conditions between adoptees with high or low genetic risk for schizophrenia spectrum disorders

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Pages 312-318 | Received 03 Jul 2023, Accepted 19 Feb 2024, Published online: 08 Mar 2024

References

  • Laursen TM, Nordentoft M, Mortensen PB. Excess early mortality in schizophrenia. Annu Rev Clin Psychol. 2014;10(1):425–448. doi:10.1146/annurev-clinpsy-032813-153657.
  • Crump C, Winkleby MA, Sundquist K, et al. Comorbidities and mortality in persons with schizophrenia: a Swedish National Cohort Study. Am J Psychiatry. 2013;170(3):324–333. doi:10.1176/appi.ajp.2012.12050599.
  • Laursen TM, Munk-Olsen T, Vestergaard M. Life expectancy and cardiovascular mortality in persons with schizophrenia. Curr Opin Psychiatry. 2012;25(2):83–88. doi:10.1097/YCO.0b013e32835035ca.
  • Oud MJ, Meyboom-de Jong B. Somatic diseases in patients with schizophrenia in general practice: their prevalence and health care. BMC Fam Pract. 2009;10(1):32. doi:10.1186/1471-2296-10-32.
  • Sørensen HJ, Nielsen PR, Benros ME, et al. Somatic diseases and conditions before the first diagnosis of schizophrenia: a nationwide population-based cohort study in more than 900 000 individuals. Schizophr Bull. 2015;41(2):513–521. doi:10.1093/schbul/sbu110.
  • Chen YL, Pan CH, Chang CK, et al. Physical illnesses before diagnosed as schizophrenia: a nationwide case-control study. Schizophr Bull. 2020;46(4):785–794. doi:10.1093/schbul/sbaa009.
  • Dieset I, Andreassen OA, Haukvik UK. Somatic comorbidity in schizophrenia: some possible biological mechanisms across the life span. Schizophr Bull. 2016;42(6):1316–1319. doi:10.1093/schbul/sbw028.
  • Ranning A, Benros ME, Thorup AAE, et al. Morbidity and mortality in the children and young adult offspring of parents with schizophrenia or affective disorders—a nationwide register-based cohort study in 2 million individuals. Schizophr Bull. 2019;46(1):130–139. doi:10.1093/schbul/sbz040.
  • Trifu SC, Kohn B, Vlasie A, et al. Genetics of schizophrenia (review). Exp Ther Med. 2020;20(4):3462–3468. doi:10.3892/etm.2020.8973.
  • Andreassen OA, Djurovic S, Thompson WK, et al. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. Am J Hum Genet. 2013;92(2):197–209. doi:10.1016/j.ajhg.2013.01.001.
  • Ripke S, Neale BM, Corvin AP, et al. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511(7510):421–427. doi:10.1038/nature13595.
  • Hoeffding LK, Rosengren A, Thygesen JH, et al. Evaluation of shared genetic susceptibility loci between autoimmune diseases and schizophrenia based on genome-wide association studies. Nord J Psychiatry. 2016;71(1):20–25. doi:10.1080/08039488.2016.1198420.
  • Cullen E, Holmes S, Pollak TA, et al. Associations between non-neurological autoimmune disorders and psychosis: a meta-analysis. Biol Psychiatry. 2019;85(1):35–48. doi:10.1016/j.biopsych.2018.06.016.
  • Gui H, Li M, Sham PC, et al. Genetic overlap between epilepsy and schizophrenia: evidence from cross phenotype analysis in Hong Kong Chinese population. Am J Med Genet B Neuropsychiatr Genet. 2017;177(1):86–92. doi:10.1002/ajmg.b.32607.
  • Kendall KM, John A, Lee SC, et al. Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: data-linkage study. BJPsych Open. 2020;6(6):e139. doi:10.1192/bjo.2020.42.
  • Clarke MC, Tanskanen A, Huttunen MO, et al. Evidence for shared susceptibility to epilepsy and psychosis: a population-based family study. Biol Psychiatry. 2012;71(9):836–839. doi:10.1016/j.biopsych.2012.01.011.
  • Gunnarsdóttir ED, Hällgren J, Hultman CM, et al. Risk of neurological, eye and ear disease in offspring to parents with schizophrenia or depression compared with offspring to healthy parents. Psychol Med. 2018;48(16):2710–2716. doi:10.1017/S0033291718000338.
  • Tienari P, Wynne LC, Moring J, et al. Finnish Adoptive Family Study: sample selection and adoptee DSM-III-R diagnoses. Acta Psychiatr Scand. 2000;101(6):433–443. doi:10.1034/j.1600-0447.2000.101006433.x.
  • Tienari P, Wynne LC, Läksy K, et al. Genetic boundaries of the schizophrenia spectrum: evidence from the Finnish Adoptive Family Study of Schizophrenia. Am J Psychiatry. 2003;160(9):1587–1594. doi:10.1176/appi.ajp.160.9.1587.
  • American Psychiatric Association. Diagnostic and statistical manual for mental disorders. 3rd ed. Washington (DC): American Psychiatric Association; 1987.
  • Wynne LC, Tienari P, Nieminen P, et al. Genotype–environment ­interaction in the schizophrenia spectrum: genetic liability and Global Family Ratings in the Finnish Adoption Study. Fam Process. 2006;45(4):419–434. doi:10.1111/j.1545-5300.2006.00180.x.
  • Miller BJ, Graham KL, Bodenheimer CM, et al. A prevalence study of urinary tract infections in acute relapse of schizophrenia. J Clin Psychiatry. 2013;74(3):271–277. doi:10.4088/JCP.12m08050.
  • Graham KL, Carson CM, Ezeoke A, et al. Urinary tract infections in acute psychosis. J Clin Psychiatry. 2014;75(4):379–385. doi:10.4088/JCP.13m08469.
  • Geerlings SE. Clinical presentations and epidemiology of urinary tract infections. Microbiol Spectr. 2016;4(5). doi:10.1128/microbiolspec.UTI-0002-2012.
  • Wallace C, Mullen PE, Burgess P, et al. Serious criminal offending and mental disorder. Br J Psychiatry. 1998;172(6):477–484. doi:10.1192/bjp.172.6.477.
  • Drake CR, Pathé M. Understanding sexual offending in schizophrenia. Crim Behav Ment Health. 2004;14(2):108–120. doi:10.1002/cbm.576.
  • De Hert M, Schreurs V, Vancampfort D, et al. Metabolic syndrome in people with schizophrenia: a review. World Psychiatry. 2009;8(1):15–22. doi:10.1002/j.2051-5545.2009.tb00199.x.

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