IL-17A and IL-23: plausible risk factors to induce age-associated inflammation in Alzheimer’s disease

References

• Ageing, W H O, Unit, L C. (2008). WHO global report on falls prevention in older age. WHO, 1–47.
   Google Scholar
• Arababadi MK, Bidaki MZ, Kennedy D. (2014). IL-17A in hepatitis B infection: friend or foe? Arch Virol, 159, 1883–1888.
   PubMed Web of Science ®Google Scholar
• Atwood CS, Martins RN, Smith MA, Perry G. (2002). Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides, 23, 1343–1350.
   PubMed Web of Science ®Google Scholar
• Bagheri V, Askari A, Arababadi MK, Kennedy D. (2014). Can Toll-Like Receptor (TLR) 2 be considered as a new target for immunotherapy against hepatitis B infection? Hum Immunol, 75, 549–554. doi:10.1016/j.humimm.2014.02.018
   PubMed Web of Science ®Google Scholar
• Behairi N, Belkhelfa M, Mesbah-Amroun H, et al. (2015). All-trans-retinoic acid modulates nitric oxide and interleukin-17A production by peripheral blood mononuclear cells from patients with Alzheimer’s disease. Neuroimmunomodulation, 22, 385–393. doi:10.1159/000435885
   PubMed Web of Science ®Google Scholar
• Belkhelfa M, Rafa H, Medjeber O, et al. (2014). IFN-gamma and TNF-alpha are involved during Alzheimer disease progression and correlate with nitric oxide production: a study in Algerian patients. J Interferon Cytokine Res, 34, 839–847. doi:10.1089/jir.2013.0085
   PubMed Web of Science ®Google Scholar
• Bijlmakers MJ, Kanneganti SK, Barker JN, et al. (2011). Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis. Hum Mol Genet, 20, 3129–3137. doi:10.1093/hmg/ddr215
   PubMed Web of Science ®Google Scholar
• Browne TC, McQuillan K, McManus RM, et al. (2013). IFN-gamma Production by amyloid beta-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer’s disease. J Immunol, 190, 2241–2251. doi:10.4049/jimmunol.1200947
   PubMed Web of Science ®Google Scholar
• Bucala R. (2014). Diabetes, aging, and their tissue complications. J Clin Investig, 124, 1887–1888. doi:10.1172/JCI75224
   PubMed Web of Science ®Google Scholar
• Chen J-H, Ke K-F, Lu J-H, et al. (2015). Protection of TGF-β1 against neuroinflammation and neurodegeneration in Aβ 1–42-induced Alzheimer’s disease model rats. PLoS One, 10, e0116549. doi:10.1371/journal.pone.0116549
   PubMed Web of Science ®Google Scholar
• Chen J-M, Jiang G-X, Li Q-W, et al. (2014). Increased serum levels of interleukin-18,-23 and-17 in chinese patients with Alzheimer’s disease. Dementia Geriatric Cognit Disord, 38, 321–329. doi:10.1159/000360606
   PubMed Web of Science ®Google Scholar
• Da Silva CA, Hartl D, Liu W, et al. (2008). TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol, 181, 4279–4286.
   PubMed Web of Science ®Google Scholar
• Degens H. (2010). The role of systemic inflammation in age-related muscle weakness and wasting. Scand J Med Sci Sports, 20, 28–38. doi:10.1111/j.1600-0838.2009.01018.x
   PubMed Web of Science ®Google Scholar
• Diaz-Gerevini GT, Repossi G, Dain A, et al. (2016). Beneficial action of resveratrol: how and why? Nutrition, 32, 174–178. doi:10.1016/j.nut.2015.08.017
   PubMed Web of Science ®Google Scholar
• Ding L-H, Liu D, Xu M, et al. (2015). TLR2–myD88–NF-κB pathway is involved in tubulointerstitial inflammation caused by proteinuria. J Biochem Cell Biol, 69, 114–120. doi:10.1016/j.biocel.2015.10.014
   PubMed Web of Science ®Google Scholar
• Doecke JD, Laws SM, Faux NG, et al. (2012). Blood-based protein biomarkers for diagnosis of Alzheimer disease. Arch Neurol, 69, 1318–1325. doi:10.1001/archneurol.2012.1282
   PubMedGoogle Scholar
• Dubois B, Feldman HH, Jacova C, et al. (2010). Revising the definition of Alzheimer’s disease: a new lexicon. Lancet Neurol, 9, 1118–1127. doi:10.1016/S1474-4422(10)70223-4
   PubMed Web of Science ®Google Scholar
• Dues DJ, Andrews EK, Schaar CE, et al. (2016). Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways. Aging (Albany NY), 8, 777–795. doi:10.18632/aging.100939
   PubMedGoogle Scholar
• Fathalizadeh J, Fathalizadeh H, Mirzabeigi M, et al. (2016). The role of interleukin-17a (il-17a) in depression. Iran Red Cres Med J, 18, e24972. doi:10.5812/ircmj.24972
   Web of Science ®Google Scholar
• Gaffen S. (2016). IL-17 receptor composition. Nat Rev Immunol, 16, 4. doi:10.1038/nri.2015.2
   PubMed Web of Science ®Google Scholar
• Gladiator A, LeibundGut-Landmann S. (2013). Innate lymphoid cells: new players in IL-17-mediated antifungal immunity. PLoS Pathog, 9, e1003763. doi:10.1371/journal.ppat.1003763
   PubMed Web of Science ®Google Scholar
• Goering J, Pope MR, Fleming SD. (2016). TLR2 regulates complement-mediated inflammation induced by blood loss during hemorrhage. Shock, 45, 33–39. doi:10.1097/SHK.0000000000000477
   PubMed Web of Science ®Google Scholar
• Griffin WS. (2013). Neuroinflammatory cytokine signaling and Alzheimer’s disease. N Engl J Med, 368, 770–771. doi:10.1056/NEJMcibr1214546
   PubMed Web of Science ®Google Scholar
• Hajjar RR, Atli T, Al-Mandhari Z, et al. (2013). Prevalence of aging population in the Middle East and its implications on cancer incidence and care. Ann Oncol, 24, vii11–24. doi:10.1093/annonc/mdt268
   PubMed Web of Science ®Google Scholar
• Happel KI, Dubin PJ, Zheng M, et al. (2005). Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J Exp Med, 202, 761–769. doi:10.1084/jem.20050193
   PubMed Web of Science ®Google Scholar
• Hu WT, Chen-Plotkin A, Grossman M, et al. (2010). Novel CSF biomarkers for frontotemporal lobar degenerations. Neurology, 75, 2079–2086. doi:10.1212/WNL.0b013e318200d78d
   PubMed Web of Science ®Google Scholar
• Hu WT, Watts K, Grossman M, et al. (2013). Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP. Neurology, 81, 1945–1952. doi:10.1212/01.wnl.0000436625.63650.27
   PubMed Web of Science ®Google Scholar
• Jin JJ, Kim HD, Maxwell JA, et al. (2008). Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer’s disease. J Neuroinflammation, 5, 23. doi:10.1186/1742-2094-5-23
   PubMed Web of Science ®Google Scholar
• Kolls JK, Linden A. (2004). Interleukin-17 family members and inflammation. Immunity, 21, 467–476. doi:10.1016/j.immuni.2004.08.018
   PubMed Web of Science ®Google Scholar
• Kondo M, Murakawa Y, Harashima N, et al. (2009). Roles of proinflammatory cytokines and the Fas/Fas ligand interaction in the pathogenesis of inflammatory myopathies. Immunology, 128, e589–599. doi:10.1111/j.1365-2567.2008.03039.x
   PubMed Web of Science ®Google Scholar
• Lambracht-Washington D, Qu B-X, Fu M, et al. (2011). DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer’s disease as it diminishes antigen-specific Th1 and Th17 cell proliferation. Cel Mole Neurobiol, 31, 867–874. doi:10.1007/s10571-011-9680-7
   PubMed Web of Science ®Google Scholar
• Ley K, Smith E, Stark MA. (2006). IL-17A-producing neutrophil-regulatory Tn lymphocytes. Immunol Res, 34, 229–242. doi:10.1385/IR:34:3:229
   PubMed Web of Science ®Google Scholar
• Liu Y, Yu JT, Zhang W, et al. (2014). Interleukin-23 receptor polymorphisms are associated with Alzheimer’s disease in Han Chinese. J Neuroimmunol, 271, 43–48. doi:10.1016/j.jneuroim.2014.03.013
   PubMed Web of Science ®Google Scholar
• Makinian M, Mirzaei T, Ravari A. (2015). The effects of head and face massage on delirium among elderly women hospitalized in coronary care units. Iran J Crit Care Nurs, 8, 125–132.
   Google Scholar
• Marcum ZA, Fried LF. (2011). Aging and antihypertensive medication-related complications in the chronic kidney disease patient. Curr Opin Nephrol Hypertens, 20, 449–456. doi:10.1097/MNH.0b013e32834902ad
   PubMed Web of Science ®Google Scholar
• Marques JM, Rial A, Munoz N, et al. (2012). Protection against Streptococcus pneumoniae serotype 1 acute infection shows a signature of Th17- and IFN-gamma-mediated immunity. Immunobiology, 217, 420–429. doi:10.1016/j.imbio.2011.10.012
   PubMed Web of Science ®Google Scholar
• Marwaha AK, Leung NJ, McMurchy AN, Levings MK. (2012). TH17 cells in autoimmunity and immunodeficiency: protective or pathogenic? Front Immunol, 3, 129. doi:10.3389/fimmu.2012.00198
   PubMed Web of Science ®Google Scholar
• McKenzie BS, Kastelein RA, Cua DJ. (2006). Understanding the IL-23-IL-17 immune pathway. Trends Immunol, 27, 17–23. doi:10.1016/j.it.2005.10.003
   PubMed Web of Science ®Google Scholar
• McManus RM, Higgins SC, Mills KH, Lynch MA. (2014). Respiratory infection promotes T cell infiltration and amyloid-beta deposition in APP/PS1 mice. Neurobiol Aging, 35, 109–121. doi:10.1016/j.neurobiolaging.2013.07.025
   PubMed Web of Science ®Google Scholar
• Meng K, Li J, Zhang A, et al. (2016). Probiotic (Enterococcus faecium) induced responses of the hepatic proteome improves metabolic efficiency of broiler chickens (Gallus gallus). BMC Genomics, 17, 89. doi:10.1186/s12864-016-3328-4
   PubMed Web of Science ®Google Scholar
• Milanova V, Ivanovska N, Dimitrova P. (2014). TLR2 elicits IL-17-mediated RANKL expression, IL-17, and OPG production in neutrophils from arthritic mice. Mediators Inflamm, 2014, 643406. doi:10.1155/2014/643406
   PubMedGoogle Scholar
• Moseley TA, Haudenschild DR, Rose L, Reddi AH. (2003). Interleukin-17 family and IL-17 receptors. Cytokine Growth Factor Rev, 14, 155–174.
   PubMed Web of Science ®Google Scholar
• Ortega C, Fernandez AS, Carrillo JM, et al. (2009). IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines. J Leukoc Biol, 86, 435–443. doi:10.1189/JLB.0109046
   PubMed Web of Science ®Google Scholar
• Parham C, Chirica M, Timans J, et al. (2002). A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R. J Immunol, 168, 5699–5708.
   PubMed Web of Science ®Google Scholar
• Pimplikar SW, Nixon RA, Robakis NK, et al. (2010). Amyloid-independent mechanisms in Alzheimer’s disease pathogenesis. J Neurosci, 30, 14946–14954. doi:10.1523/JNEUROSCI.4305-10.2010
   PubMed Web of Science ®Google Scholar
• Pinti M, Cevenini E, Nasi M, et al. (2014). Circulating mitochondrial DNA increases with age and is a familiar trait: implications for “ inflamm- aging”. Europ J Immunol, 44, 1552–1562. doi:10.1002/eji.201343921
   PubMed Web of Science ®Google Scholar
• Ravari A, Mirzaei T, Kennedy D, Kazemi Arababadi M. (2017). Chronoinflammaging in Alzheimer; A systematic review on the roles of toll like receptor 2. Life Sci, 171, 16–20. doi:10.1016/j.lfs.2017.01.003
   Google Scholar
• Ravari A, Mirzaei T, Salamizadeh A, Askari-Majdabadi H. (2017). The effect of the spiritual care training on anxiety reduction in home caregivers of the elderly with Alzheimer. Koomesh, 19, 467–474.
   Google Scholar
• Roark CL, French JD, Taylor MA, et al. (2007). Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells. J Immunol, 179, 5576–5583.
   PubMed Web of Science ®Google Scholar
• Saresella M, Calabrese E, Marventano I, et al. (2011). Increased activity of Th-17 and Th-9 lymphocytes and a skewing of the post-thymic differentiation pathway are seen in Alzheimer’s disease. Brain Behav Immunity, 25, 539–547. doi:10.1016/j.bbi.2010.12.004
   PubMed Web of Science ®Google Scholar
• Saresella M, Marventano I, Calabrese E, et al. (2014). A complex proinflammatory role for peripheral monocytes in Alzheimer’s disease. J Alzheimers Dis, 38, 403–413. doi:10.3233/JAD-131160
   PubMed Web of Science ®Google Scholar
• Schulz SM, Köhler G, Holscher C, et al. (2008). IL-17A is produced by Th17, γδ T cells and other CD4− lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance. Int Immunol, 20, 1129–1138. doi:10.1093/intimm/dxn069
   PubMed Web of Science ®Google Scholar
• Sepehri Z, Kiani Z, Alavian SM, et al. (2016). The link between TLR7 signaling and hepatitis B virus infection. Life Sci, 158, 63–69. doi:10.1016/j.lfs.2016.06.026
   PubMed Web of Science ®Google Scholar
• Shaftel SS, Kyrkanides S, Olschowka JA, et al. (2007). Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J Clin Invest, 117, 1595–1604. doi:10.1172/JCI31450
   PubMed Web of Science ®Google Scholar
• Shibata N, Ohnuma T, Takahashi T, et al. (2002). Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases. Am J Med Genet, 114, 436–439. doi:10.1002/ajmg.10417
   PubMed Web of Science ®Google Scholar
• Soysal P, Stubbs B, Lucato P, et al. (2016). Inflammation and frailty in the elderly: A systematic review and meta-analysis. Ageing Res Rev, 31, 1–8. doi:10.1016/j.arr.2016.08.006
   PubMed Web of Science ®Google Scholar
• Takahashi M, Kobayashi Y. (2003). Cytokine production in association with phagocytosis of apoptotic cells by immature dendritic cells. Cell Immunol, 226, 105–115. doi:10.1016/j.cellimm.2003.11.008
   PubMed Web of Science ®Google Scholar
• Tan MS, Yu JT, Jiang T, et al. (2014). IL12/23 p40 inhibition ameliorates Alzheimer’s disease-associated neuropathology and spatial memory in SAMP8 mice. J Alzheimers Dis, 38, 633–646. doi:10.3233/JAD-131148
   PubMed Web of Science ®Google Scholar
• Vaknin-Dembinsky A, Balashov K, Weiner HL. (2006). IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol, 176, 7768–7774.
   PubMed Web of Science ®Google Scholar
• Volt H, Garcia JA, Doerrier C, et al. (2016). Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res, 60, 193–205. doi:10.1111/jpi.12303
   PubMed Web of Science ®Google Scholar
• Vom Berg J, Prokop S, Miller KR, et al. (2012). Inhibition of IL-12/IL-23 signaling reduces Alzheimer’s disease-like pathology and cognitive decline. Nat Med, 18, 1812–1819. doi:10.1038/nm.2965
   PubMed Web of Science ®Google Scholar
• von Vietinghoff S, Ley K. (2009). IL-17A controls IL-17F production and maintains blood neutrophil counts in mice. J Immunol, 183, 865–873. doi:10.4049/jimmunol.0804080
   PubMed Web of Science ®Google Scholar
• Wang C, Klechikov AG, Gharibyan AL, et al. (2014). The role of pro-inflammatory S100A9 in Alzheimer’s disease amyloid-neuroinflammatory cascade. Acta Neuropathol, 127, 507–522. doi:10.1007/s00401-013-1208-4
   PubMed Web of Science ®Google Scholar
• Wang J-H, Cheng X-R, Zhang X-R, et al. (2016). Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrP-hAβPPswe/PS1ΔE9 mice: potential mechanism underlying cognitive impairment. Oncotarget, 7, 22988–23005. doi:10.18632/oncotarget.8453
   PubMedGoogle Scholar
• Wraith DC. (2006). Anti-cytokine vaccines and the immunotherapy of autoimmune diseases. Eur J Immunol, 36, 2844–2848. doi:10.1002/eji.200636760
   PubMed Web of Science ®Google Scholar
• Yehuda S, Rabinovitz S. (2015). Fatty acids rehabilitated long-term neurodegenerative: like symptoms in olfactory bulbectomized rats. J Neural Transm (Vienna), 122, 629–641. doi:10.1007/s00702-014-1321-0
   PubMed Web of Science ®Google Scholar
• Yin Y, Wen S, Li G, Wang D. (2009). Hypoxia enhances stimulating effect of amyloid beta peptide (25-35) for interleukin 17 and T helper lymphocyte subtype 17 upregulation in cultured peripheral blood mononuclear cells. Microbiol Immunol, 53, 281–286. doi:10.1111/j.1348-0421.2009.00120.x
   PubMed Web of Science ®Google Scholar
• Zenaro E, Pietronigro E, Della Bianca V, et al. (2015). Neutrophils promote Alzheimer’s disease-like pathology and cognitive decline via LFA-1 integrin. Nat Med, 21, 880–886. doi:10.1038/nm.3913
   PubMed Web of Science ®Google Scholar
• Zhang J, Ke K-F, Liu Z, et al. (2013). Th17 cell-mediated neuroinflammation is involved in neurodegeneration of Aβ 1-42-induced Alzheimer’s disease model rats. PLoS One, 8, e75786. doi:10.1371/journal.pone.0075786
   PubMed Web of Science ®Google Scholar
• Zota V, Nemirovsky A, Baron R, et al. (2009). HLA-DR alleles in amyloid beta-peptide autoimmunity: a highly immunogenic role for the DRB1*1501 allele. J Immunol, 183, 3522–3530. doi:10.4049/jimmunol.0900620
   PubMed Web of Science ®Google Scholar