262
Views
3
CrossRef citations to date
0
Altmetric
Original Articles

TNF May Negatively Regulate Phagocytosis of Devil Facial Tumour Disease Cells by Activated Macrophages

, , , & ORCID Icon

References

  • Aderem A, Underhill DM. (1999). Mechanisms of phagocytosis in macrophages. Annu Rev Immunol, 17, 593–623. doi: 10.1146/annurev.immunol.17.1.593
  • Alvey C, Discher DE. (2017). Engineering macrophages to eat cancer: from “marker of self” CD47 and phagocytosis to differentiation. J Leukoc Biol, 102, 31–40. doi: 10.1189/jlb.4RI1216-516R
  • Borges VM, Vandivier RW, McPhillips KA, et al. (2009). TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation. Am J Physiol Lung Cell Mol Physiol. 297, L586–595. doi: 10.1152/ajplung.90569.2008
  • Chan ED, Riches DW. (2001). IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/ SAPK,and p38(mapk) in a mouse macrophage cell line. Am J Physiol Cell Physiol, 280, C441–450. doi: 10.1152/ajpcell.2001.280.3.C441
  • Cohen HB, Ward A, Hamidzadeh K, et al. (2015). IFN-gamma prevents adenosine receptor (A2bR) upregulation to sustain the macrophage activation response. J Immunol, 195, 3828–3837. doi: 10.4049/jimmunol.1501139
  • Ding AH, Nathan CF, Stuehr DJ. (1988). Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol, 141, 2407–2412.
  • Feng X, Deng T, Zhang Y, et al. (2011). Lipopolysaccharide inhibits macrophage phagocytosis of apoptotic neutrophils by regulating the production of tumour necrosis factor alpha and growth arrest-specific gene 6. Immunology, 132, 287–295. doi: 10.1111/j.1365-2567.2010.03364.x
  • Fernandez-Boyanapalli R, McPhillips KA, Frasch SC, et al. (2010). Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-gamma in a nitric oxide-dependent manner. J Immunol, 185, 4030–4041. doi: 10.4049/jimmunol.1001778
  • Flies AS, Blackburn NB, Lyons AB, et al. (2017). Comparative analysis of immune checkpoint molecules and their potential role in the transmissible tasmanian devil facial Tumor Disease. Front Immunol, 8, 513. doi: 10.3389/fimmu.2017.00513
  • Gifford GE, Lohmann-Matthes ML. (1987). Gamma interferon priming of mouse and human macrophages for induction of tumor necrosis factor production by bacterial lipopolysaccharide. J Natl Cancer Inst, 78, 121–124.
  • Gordon S, Martinez FO. (2010). Alternative activation of macrophages: mechanism and functions. Immunity, 32, 593–604. doi: 10.1016/j.immuni.2010.05.007
  • Hu S, Wei W, Korner H. (2017). The role of monocytes in models of infection by protozoan parasites. Mol Immunol, 88, 174–184. doi: 10.1016/j.molimm.2017.06.020
  • Jones ME, Cockburn A, Hamede R, et al. (2008). Life-history change in disease-ravaged Tasmanian devil populations. Proc Natl Acad Sci U S A, 105, 10023–10027. doi: 10.1073/pnas.0711236105
  • Jun CD, Han MK, Kim UH, Chung HT. (1996). Nitric oxide induces ADP-ribosylation of actin in murine macrophages: association with the inhibition of pseudopodia formation, phagocytic activity, and adherence on a laminin substratum. Cell Immunol, 174, 25–34. doi: 10.1006/cimm.1996.0290
  • Körner H, Cook M, Riminton DS, et al. (1997). Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue. Eur. J. Immunol, 27, 2600–2609. doi: 10.1002/eji.1830271020
  • Kratochvill F, Neale G, Haverkamp JM, et al. (2015). TNF counterbalances the emergence of M2 tumor macrophages. Cell Rep, 12, 1902–1914. doi: 10.1016/j.celrep.2015.08.033
  • Kreiss A, Brown GK, Tovar C, et al. (2015). Evidence for induction of humoral and cytotoxic immune responses against devil facial tumor disease cells in Tasmanian devils (Sarcophilus harrisii) immunized with killed cell preparations. Vaccine, 33, 3016–3025. doi: 10.1016/j.vaccine.2015.01.039
  • Kreiss A, Obendorf DL, Hemsley S, et al. (2009). A histological and immunohistochemical analysis of lymphoid tissues of the Tasmanian devil. Anat Rec (Hoboken), 292, 611–620. doi: 10.1002/ar.20896
  • Leichtle A, Hernandez M, Ebmeyer J, et al. (2010). CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF-/- mice. J Immunol. 184, 3087–3097. doi: 10.4049/jimmunol.0901167
  • MacMicking J, Xie QW, Nathan C. (1997). Nitric oxide and macrophage function. Annu Rev Immunol, 15, 323–350. doi: 10.1146/annurev.immunol.15.1.323
  • Mannel DN, Moore RN, Mergenhagen SE. (1980). Macrophages as a source of tumoricidal activity (tumor-necrotizing factor). Infect. Immun., 30, 523–530.
  • McPhillips K, Janssen WJ, Ghosh M, et al. (2007). TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms. J Immunol, 178, 8117–8126.
  • Murray PJ, Allen JE, Biswas SK, et al. (2014). Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity. 41, 14–20. doi: 10.1016/j.immuni.2014.06.008
  • Parameswaran N, Patial S. (2010). Tumor necrosis factor-alpha signaling in macrophages. Crit Rev Eukaryot Gene Expr, 20, 87–103.
  • Patel NR, Bole M, Chen C, et al. (2012). Cell elasticity determines macrophage function. PLoS ONE. 7, e41024. doi: 10.1371/journal.pone.0041024
  • Pearse AM, Swift K, Hodson P, et al. (2012). Evolution in a transmissible cancer: a study of the chromosomal changes in devil facial tumor (DFT) as it spreads through the wild Tasmanian devil population. Cancer Genet, 205, 101–112. doi: 10.1016/j.cancergen.2011.12.001
  • Peppelenbosch M, Boone E, Jones GE, et al. (1999). Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF. J Immunol, 162, 837–845.
  • Pye R, Hamede R, Siddle HV, et al. (2016a). Demonstration of immune responses against devil facial tumour disease in wild Tasmanian devils. Biol Lett, 12. doi: 10.1098/rsbl.2016.0553
  • Pye RJ, Pemberton D, Tovar C, et al. (2016b). A second transmissible cancer in Tasmanian devils. Proc Natl Acad Sci U S A. 113, 374–379. doi: 10.1073/pnas.1519691113
  • Schleicher U, Bogdan C. (2009). Generation, culture and flow-cytometric characterization of primary mouse macrophages. Methods Mol. Biol., 531, 203–224. doi: 10.1007/978-1-59745-396-7_14
  • Schleicher U, Paduch K, Debus A, et al. (2016). TNF-mediated restriction of arginase 1 expression in myeloid cells triggers type 2 NO Synthase activity at the site of infection. Cell Rep. 15, 1062–1075. doi: 10.1016/j.celrep.2016.04.001
  • Sedgwick JD, Riminton DS, Cyster JG, Körner H. (2000). Tumor necrosis factor: a master-regulator of leukocyte movement. Immunol Today, 21, 110–113.
  • Siddle HV, Kreiss A, Tovar C, et al. (2013). Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer. Proc Natl Acad Sci U S A. 110, 5103–5108. doi: 10.1073/pnas.1219920110
  • Tauber AI. (2003). Metchnikoff and the phagocytosis theory. Nat Rev Mol Cell Biol, 4, 897–901. doi: 10.1038/nrm1244
  • Taylor PR, Martinez-Pomares L, Stacey M, et al. (2005). Macrophage receptors and immune recognition. Annu Rev Immunol, 23, 901–944. doi: 10.1146/annurev.immunol.23.021704.115816
  • Tjelle TE, Lovdal T, Berg T. (2000). Phagosome dynamics and function. Bioessays, 22, 255–263. doi: 10.1002/(SICI)1521-1878(200003)22:3<255::AID-BIES7>3.0.CO;2-R
  • Tovar C, Pye RJ, Kreiss A, et al. (2017). Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils. Sci Rep. 7, 43827. doi: 10.1038/srep43827
  • Underhill DM, Ozinsky A. (2002). Phagocytosis of microbes: complexity in action. Annu Rev Immunol, 20, 825–852. doi: 10.1146/annurev.immunol.20.103001.114744
  • Varin A, Mukhopadhyay S, Herbein G, Gordon S. (2010). Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion. Blood, 115, 353–362. doi: 10.1182/blood-2009-08-236711
  • Vila-Del Sol V, Punzon C, Fresno M. (2008). IFN-gamma-induced TNF-alpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages. J Immunol, 181, 4461–4470.
  • Wilhelm P, Ritter U, Labbow S, et al. (2001). Rapidly fatal leishmaniasis in resistant C57BL/6 mice lacking TNF. J. Immunol., 166, 4012–4019.
  • Zhou Z, Yu X. (2008). Phagosome maturation during the removal of apoptotic cells: receptors lead the way. Trends Cell Biol, 18, 474–485. doi: 10.1016/j.tcb.2008.08.002

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.