References
- Mackay I.R., Rose N.R. “The Autoimmune Diseases”, N. R. Rose, I. R. Mackay. Academic Press, Sydney 1998
- Alderuccio F., Sentry J.W., Marshall A.C., Biondo M., Toh B.H. Animal models of human disease: experimental autoimmune gastritis—a model for autoimmune gastritis and pernicious anemia. Clin. Immunol. 2002; 102: 48–58, [PUBMED], [INFOTRIEVE]
- Nishio A., Hosono M., Watanabe Y., Sakai M., Okuma M., Masuda T. A conserved epitope on H+, K+-adenosine triphosphatase of parietal cells discerned by a murine gastritogenic T-cell clone. Gastroenterology 1994; 107: 1408–1414, [PUBMED], [INFOTRIEVE]
- Suri-Payer E., Amar A.Z., Mchugh R., Natarajan K., Margulies D.H., Shevach E.M. Post-thymectomy auoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells. Eur. J. Immunol. 1999; 29: 669–677, [PUBMED], [INFOTRIEVE], [CROSSREF]
- de Silva H.D., Gleeson P.A., Toh B.H., van Driel I.R., Carbone F.R. Identification of a gastritogenic epitope of the H/K ATPase β-subunit. Immunology 1999; 96: 145–151, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Katakai T., Agata Y., Shimizu A., Ohshima C., Nishio A., Inaba M., Kasakura S., Mori K.J., Masuda T. Structure of the TCR expressed on a gastritogenic T cell clone, II-6, and frequent appearance of similar clonotypes in mice bearing autoimmune gastritis. Inter. Immunol. 1997; 9: 1849–1855, [CROSSREF]
- Amedei A., Bergman M.P., Appelmelk B.J., Azzurri A., Benagiano M., Tamburini C., van der Zee R., Telford J.L., Vandenbroucke-Grauls C.M., D'Elios M.M., Del Prete G. Molecular mimicry between Helicobacter pylori antigens and H+, K+-adenosine triphosphatase in human gastric autoimmunity. J. Exp. Med. 2003; 198: 1147–1156, [PUBMED], [INFOTRIEVE], [CROSSREF]
- D'Elios M.M., Bergman M.P., Azzurri A., Amedei A., Benagiano M., De Pont J.J., Cianchi F., Vandenbroucke-Grauls C.M., Romagnani S., Appelmelk B.J., Del Prete G. H(+),K(+)-atpase (proton pump) is the target autoantigen of Th1-type cytotoxic T cells in autoimmune gastritis. Gastroenterology 2001; 120: 377–386, [PUBMED], [INFOTRIEVE]
- Kojima A., Prehn R.T. Genetic susceptibility to post-thymectomy autoimmune diseases in mice. Immunogenetics 1981; 14: 15–27, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Fukuma K., Sakaguchi S., Kuribayashi K., Chen W.-L., Morishita R., Sekita K., Uchino H., Masuda T. Immunologic and clinical studies in murine experimental autoimmune gastritis induced by neonatal thymectomy. Gastroenterology 1988; 94: 274–283, [PUBMED], [INFOTRIEVE]
- van Driel I.R., Baxter A.G., Laurie K.L., Zwar T.D., La Gruta N.L., Judd L.M., Scarff K.L., Silveira P.A., Gleeson P.A. Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis. Autoimmun. Rev. 2002; 1: 290–297, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Toh B., Sentry J., Alderuccio F. The Molecular Pathology of Autoimmune Diseases, A. N. Theofilopoulos, C. A. Bona. 2nd, Sheridan Books, Ann Arbor, MI 2002
- Gleeson P.A., Toh B.H., van Driel I.R. Organ-specific autoimmunity induced by lymphopenia. Immunol. Rev. 1996; 149: 97–125, [PUBMED], [INFOTRIEVE]
- McHugh R.S., Shevach E.M. The role of suppressor T cells in regulation of immune responses. J. Allergy Clin. Immunol. 2002; 110: 693–702, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Shevach E.M., Piccirillo C.A., Thornton A.M., McHugh R.S. Control of T cell activation by CD4+CD25+ suppressor T cells. Novartis Found. Symp. 2003; 252: 24–36, 36–44, 106–114 [PUBMED], [INFOTRIEVE]
- Martinelli T.M., van Driel I.R., Alderuccio F., Gleeson P.A., Toh B.H. Analysis of mononuclear cell infiltrate and cytokine production in Murine autoimmune gastritis. Gastroenterology 1996; 110: 1791–1802, [PUBMED], [INFOTRIEVE]
- Stampfli M.R., Wiley R.E., Neigh G.S., Gajewska B.U., Lei X.F., Snider D.P., Xing Z., Jordana M. GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice. J. Clin. Invest. 1998; 102: 1704–1714, [PUBMED], [INFOTRIEVE]
- Lang R.A., Metcalf D., Cuthbertson R.A., Lyons I., Stanley E., Kelso A., Kannourakis G., Williamson D.J., Klintworth G.K., Gonda T.J., Dunn A.R. Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage. Cell 1987; 51: 675–686, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Alderuccio F., Biondo M., Toh B.H. Organ-specific autoimmunity in granulocyte macrophage-colony stimulating factor (GM-CSF) deficient mice. Autoimmunity 2002; 35: 67–73, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Biondo M., Nasa Z., Marshall A., Toh B.H., Alderuccio F. Local transgenic expression of granulocyte macrophage-colony stimulating factor initiates autoimmunity. J. Immunol. 2001; 166: 2090–2099, [PUBMED], [INFOTRIEVE]
- Scheinecker C., McHugh R., Shevach E.M., Germain R.N. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 2002; 196: 1079–1090, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Toh B.H., van Driel I.R., Gleeson P.A. Pernicious anaemia. N. Engl. J. Med. 1997; 337: 1441–1448, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Kojima A., Taguchi O., Nishizuka Y. Experiental production of possible autoimmune gastritis followed by macrocytic anemia in athymic nude mice. Lab. Invest 1980; 42: 387–395, [PUBMED], [INFOTRIEVE]
- Toh B.H., Gleeson P.A., Simpson R.J., Moritz R.L., Callaghan J.M., Goldkorn I., Jones C.M., Martinelli T.M., Mu F.-T., Humphris D.C., Pettitt J.M., Mori Y., Masuda T., Sobieszczuk P., Weinstock J., Mantamadiotis T., Baldwin G.S. The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a β subunit of the gastric H+/K+-ATPase (proton pump). Proc. Nat. Acad. Sci. 1990; 87: 6418–6422, [PUBMED], [INFOTRIEVE]
- Alderuccio F., Toh B.H., Tan S.S., Gleeson P.A., van Driel I.R. An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus. J. Exp. Med. 1993; 178: 419–426, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Alderuccio F., Gleeson P.A., Berzins S.P., Martin M., van Driel I.R., Toh B.H. Expression of the gastric H/K ATPase a-subunit in the thymus may explain the dominant role of the β-subunit in the pathogenesis of autoimmune gastritis. Autoimmunity 1997; 25: 167–175, [PUBMED], [INFOTRIEVE]
- Lehmann P.V., Forsthuber T., Miller A., Sercarz E.E. Spreading of T-Cell autoimmunity to cryptic determinants to an autoantigen. Nature 1992; 358: 155–157, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Tisch R., Yang X.D., Singer S.M., Liblau R.S., Fugger L., McDevitt H.O. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 1993; 366: 72–75, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Tuohy V.K., Yu M., Yin L., Kawczak J.A., Kinkel R.P. Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis [see comments]. J. Exp. Med. 1999; 189: 1033–1042, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Barrett S.P., Toh B.H., Alderuccio F., van Driel I.R., Gleeson P.A. Organ-specific autoimmunity induced by adult thymectomy and cyclosphamide-induced lymphopenia. Eur. J. Immunol. 1995; 25: 238–244, [PUBMED], [INFOTRIEVE]
- Sakaguchi S., Ermak T.H., Toda M., Berg L.J., Ho W., Fazekas de St.Groth B., Peterson P.A., Sakaguchi N., Davis M.M. Induction of autoimmune disease in mice by germline alteration of the T cell receptor gene expression. J. Immunol. 1994; 152: 1471–1484, [PUBMED], [INFOTRIEVE]
- Murphy K., Biondo M., Toh B.H., Alderuccio F. Tolerance established in autoimmune disease by mating or bone marrow transplantation that target autoantigen to thymus. Inter. Immunol. 2003; 15: 1–9, [CROSSREF]
- Asano M., Toda M., Sakaguchi N., Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 1996; 184: 387–396, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Brocker T., Riedinger M., Karjalainen K. Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo. J. Exp. Med. 1997; 185: 541–550, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Liston A., Lesage S., Wilson J., Peltonen L., Goodnow C.C. Aire regulates negative selection of organ-specific T cells. Nat. Immunol. 2003; 4: 350–354, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Anderson M.S., Venanzi E.S., Klein L., Chen Z., Berzins S.P., Turley S.J., von Boehmer H., Bronson R., Dierich A., Benoist C., Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science 2002; 298: 1395–1401, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Derbinski J., Schulte A., Kyewski B., Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2001; 2: 1032–1039, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Kyewski B., Derbinski J., Gotterm J., Klein L. Promiscuous gene expression and central T-cell tolerance: more than meets the eye. Trends Immunol. 2002; 23: 364–371, [PUBMED], [INFOTRIEVE], [CROSSREF]
- French M.B., Allison J., Cram D.S., Thomas H.E., Dempsey-Collier M., Silva A., Georgiou H.M., Kay T.W., Harrison L.C., Lew A.M. Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. Diabetes 1997; 46: 34–39, [published erratum appears in Diabetes46(5): 924 (1997)] [PUBMED], [INFOTRIEVE]
- Xu H., Wawrousek E.F., Redmond T.M., Nickerson J.M., Wiggert B., Chan C.C., Caspi R.R. Transgenic expression of an immunologically privileged retinal antigen extraocularly enhances self tolerance and abrogates susceptibility to autoimmune uveitis. Eur. J. Immunol. 2000; 30: 272–278, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Marmont A.M. New horizons in the treatment of autoimmune diseases: immunoablation and stem cell transplantation. Ann. Rev. Med. 2000; 51: 115–34, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Slavin S. New strategies for bone marrow transplantation. Curr. Opin. Immunol. 2000; 12: 542–551, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Burt R.K., Slavin S., Burns W.H., Marmont A.M. Induction of tolerance in autoimmune disease by hematopoietic stem cell transplantation: getting closer to a cure?. Blood 2002; 99: 768–784, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Karussis D.M., Vourka U.-Karussis, Lehmann D., Abramsky O., Ben-Nun A., Slavin S. Immunomodulation of autoimmunity in MRL/lpr mice with syngeneic bone marrow transplantation (SBMT). Clin. Exper. Immunol. 1995; 100: 111–117
- van Bekkum D.W. Stem cell transplantation in experimental models of autoimmune disease. J. Clin. Immunol. 2000; 20: 10–16, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Traynor A.E., Schroeder J., Rosa R.M., Cheng D., Stefka J., Mujais S., Baker S., Burt R.K. Treatment of severe systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem-cell transplantation: a phase I study. Lancet 2000; 356: 701–707, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Lampeter E.F., Homberg M., Quabeck K., Schaefer U.W., Wernet P., Bertrams J., Grosse-Wilde H., Gries F.A., Kolb H. Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation [see comments]. Lancet 1993; 341: 1243–1244, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Couzin J. Immunology. Gently soothing a savage immune system. Science 2002; 296: 456–458, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Shortman K., Vremec D., Corcoran L.M., Georgopoulos K., Lucas K., Wu L. The linkage between T-cell and dendritic cell development in the mouse thymus. Immunol. Rev. 1998; 165: 39–46, [PUBMED], [INFOTRIEVE]
- van Bekkum D.W. Autologous hematopoietic stem cell transplantation for autoimmune diseases: experimental basis for the treatment of autoimmune diseases with autologous hematipoietic stem cell transplantation. Bone Marrow Transplantation 2003; 32: S37–S39, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Karam S.M. Lineage commitment and maturation of epithelial cells in the gut. Front Biosci 1999; 4: D286–D298, [PUBMED], [INFOTRIEVE]
- Steptoe R.J., Ritchie J.M., Harrison L.C. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J. Clin. Invest. 2003; 111: 1357–1363, [PUBMED], [INFOTRIEVE], [CROSSREF]
- de Silva H.D., van Driel I.R., La Gruta N., Toh B.H., Gleeson P.A. CD4+ T cells, but not CD8+ T cells, are required for the development of experimental autoimmune gastritis. Immunology 1998; 93: 405–408, [PUBMED], [INFOTRIEVE]
- Barrett S.P., Riordon A., Toh B.H., Gleeson P.A., van Driel I.R. Homing and adhesion molecules in autoimmune gastritis. Journal of Leukocyte Biology 2000; 67: 169–173, [PUBMED], [INFOTRIEVE]
- Barrett S.P., Gleeson P.A., de Silva H.D., Toh B.H., van Driel I.R. Interferon-γ is required during the initiation of an organ-specific autoimmune disease. Eur. J. Immunol. 1996; 26: 1652–1655, [PUBMED], [INFOTRIEVE]
- Marshall A.C., Alderuccio F., Toh B.H. Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis. Gastroenterology 2002; 123: 780–789, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Marshall A.C.J., Toh B.-H., Alderuccio F. Tumor necrosis factor alpha is not implicated in the genesis of experimental autoimmune gastritis. J. Autoimm 2004; 22: 1–11, [CROSSREF]
- Plater-Zyberk C., Hoogewerf A.J., Proudfoot A.E., Power C.A., Wells T.N. Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice. Immunol. Lett. 1997; 57: 117–120, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Field J., Marshall A.C., P J., Wells T.N., Alderuccio F., Toh B.H. Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis. Clin. Immunol. 2003; 109: 238–247, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Hacein S.-Bey-Abina, von Kalle C., Schmidt M., Le Deist F., Wulffraat N., McIntyre E., Radford I., Villeval J.L., Fraser C.C., Cavazzana-Calvo M., Fischer A. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 2003; 348: 255–256, [CROSSREF]
- Bank A. Hematopoietic stem cell gene therapy: selecting only the best. J. Clin. Invest 2003; 112: 1478–1480, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Gugasyan R., Quilici C., I S.T.T., Grail D., Verhagen A.M., Roberts A., Kitamura T., Dunn A.R., Lock P. Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites. J. Cell Biol. 2002; 158: 115–125, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Wekerle T., Sykes M. Mixed chimerism and transplantation tolerance. Ann. Rev. Med. 2001; 52: 353–370, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Wall A.J., Whittingham S., Mackay I.R., Ungar B. Prednisolone and gastric atrophy. Clin. Exp. Immunol. 1968; 3: 359–366, [PUBMED], [INFOTRIEVE]
- Scarff K.J., Pettitt J.M., van Driel I.R., Gleeson P.A., Toh B.H. Immunization with gastric H+/K+-ATPase induces a reversible autoimmune gastritis. Immunology 1997; 92: 91–98, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Canfield V., West A.B., Goldenring J.R., Levenson R. Genetic ablation of parietal cells in transgenic mice: a new model for analyzing cell lineage relationships in the gastric mucosa. Proc. Natl. Acad. Sci. USA 1996; 93: 2431–2435, [PUBMED], [INFOTRIEVE], [CROSSREF]