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Laboratory Study

Oxidative stress, NOx/l-arginine ratio and glutathione/glutathione S-transferase ratio as predictors of ‘sterile inflammation’ in patients with alcoholic cirrhosis and hepatorenal syndrome type II

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Pages 340-349 | Received 18 Oct 2017, Accepted 15 Mar 2018, Published online: 16 Apr 2018

References

  • Arroyo V, Fernandez J, Ginès P. Pathogenesis and treatment of hepatorenal syndrome. Semin Liver Dis. 2008;28:81–95.
  • Bolognesi M, Pascoli M, Verardo A, et al. Splanchnic vasodilation and hyperdynamic circulatory syndrome in cirrhosis. World J Gastroenterol. 2014;20:2555–2563.
  • Salerno F, Gerbes A, Ginès P, et al. Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis. Gut. 2007;56:1310–1318.
  • Blendis L, Wong F. The natural history and management of hepatorenal disorders: from pre-ascites to hepatorenal syndrome. Clin Med (Lond). 2003;3: 154–159.
  • Arroyo V, Guevara M, Ginès P. Hepatorenal syndrome in cirrhosis: pathogenesis and treatment. Gastroenterology. 2002;122:1658–1676.
  • Rao K, Seth A, Sheth P. Recent advances in alcoholic liver disease: role of intestinal permeability and endotoxemia in alcoholic liver disease. Am J Physiol. 2004;286:G881–G884.
  • Cederbaum I, Lu Y, Wu D. Role of oxidative stress in alcohol-induced liver injury. Arch Toxicol. 2009;83: 519–548.
  • Niki E. Lipid peroxidation products as oxidative stress biomarkers. Biofactors. 2008;34:171–180.
  • Chen G, Nunez G. Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol. 2010;10: 826–837.
  • Piccinini AM, Midwood KS. DAMPening inflammation by modulating TLR signalling. Mediators Inflamm. 2010;2010:672395.
  • Pizzimenti S, Toaldo C, Pettazzoni P, et al. The “Two-Faced” effects of reactive oxygen species and the lipid peroxidation product 4-hydroxynonenal in the hallmarks of cancer. Cancers. 2010;2:338–363.
  • Albano E. New concepts in the pathogenesis of alcoholic liver disease. Expert Rev Gastroenterol Hepatol. 2008;2:749–759.
  • Ničković V, Nikolić J, Kocić G, et al. Complications of alcoholic liver disease and diagnostic markers. Acta Medica Medianae. 2011;50:55–61.
  • Sies H. Glutathione and its role in cellular functions. Free Radic Biol Med. 1999;27:916–921.
  • Lushchak VI. Glutathione homeostasis and functions: potential targets for medical interventions. J Amino Acids. 2012;2012:736837.
  • Zuwała-Jagiełło J, Pazgan-Simon M, Simon K, et al. Advanced oxidation protein products and inflammatory markers in liver cirrhosis: a comparison between alcohol-related and HCV-related cirrhosis. Acta Biochemica Polonica. 2011;58:59–66.
  • Witko-Sarsat V, Friedlander M, Nguyen Khoa T, et al. Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure. J Immunol. 1998;161:2524–2532.
  • Nicković V, Nikolić J, Djindjić N, et al. Diagnostical significance of dimethylarginine in the development of hepatorenal syndrome in patients with alcoholic liver cirrhosis. Vojnosanitetski Pregled. 2012;69:686–691.
  • Angeli P, Merkel C. Pathogenesis and management of hepatorenal syndrome in patients with cirrhosis. J Hepatol. 2008;48:S93–S103.
  • Shuo Hu L, George J, Wang J. Current concepts on the role of nitric oxide in portal hypertension. World J Gastroenterol. 2013;19:1707–1717.
  • Madan K, Mehta A. Management of renal failure and ascites in patients with cirrhosis. Int J Hepatol. 2011;2011:790232.
  • Iwakiri Y, Groszmann J. Vascular endothelial dysfunction in cirrhosis. J Hepatol. 2007;46:927–934.
  • Ledwozyd A, Michalak B, Stepien A, et al. The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis. Clin Chim Acta.1986;155:275–284.
  • Sedlak J, Lindsay H. Estimation of total, protein-bound, and nonprotein sulfydryl groups in tissue with Ellman’s reagent. Anal Biochem. 1968;25:192–205.
  • Habig H, Pabst J, Jakoby B. Glutathione-S-transferases. J Biol Chem. 1974;249:7130–7134.
  • Đorđević V, Pavlović D. Methods for determination of NO and products of nitrosylation. In: Djordjevic V, editor. Biochemical markers of oxidative stress in experimental and clinical medicine. Niš: Medical Faculty Nis; 2006; p. 123.
  • Nlemelä O, Parkkila S, Ylä-herttuala S, et al. Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease issue. Hepatology. 2005;22:1208–1214.
  • Vuppalanchi R, Juluri R, Bell LN, et al. Oxidative stress in chronic liver disease: relationship between peripheral and hepatic measurements. Am J Med Sci. 2011; 342:314–317.
  • Duryee J, Willis S, Freeman L, et al. Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity. Front Biosci. 2004;9:3145–3155.
  • McVicker B, Tuma D, Kharbanda K, et al. Effect of chronic ethanol administration on the in vitro production of proinflammatory cytokines by rat Kupffer cells in the presence of apoptotic cells. Alcoholism Clin Exp Res. 2007;31:122–129.
  • Thiele M, Duryee J, Willis S, et al. Malondialdehyde-acetaldehyde (MAA) modified proteins induce proinflammatory and pro-fibrotic responses by liver endothelial cells. Comp Hepatol. 2004;3:1–25.
  • Aleynik I, Leo A, Aleynik K, et al. Increased circulating products of lipid peroxidation in patients with alcoholic liver disease. Alcoholism Clin Exp Res. 2006;22: 192–196.
  • Mortensen C, Andersen O, Krag A, et al. High-sensitivity C-reactive protein levels predict survival and are related to haemodynamics in alcoholic cirrhosis. Eur J Gastroenterol Hepatol. 2012;24:619–626.
  • Rouach H, Fataccioli V, Gentil M, et al. Effect of chronic ethanol feeding on lipid peroxidation and protein oxidation in relation to liver pathology. Hepatology. 1997;25(2):351–355.
  • Alderton W, Cooper C, Knowles R. Nitric oxide synthases: structure, function and inhibition. Biochem J. 2001;357:593–615.
  • Ničković V, Kocić G, Bjelaković G, et al. Diagnostic significance of nitrates and nitrites and L-arginine, in development of hepatorenal syndrome in patients with end stage alcoholic liver cirrhosis. Ren Fail. 2013;35(5):633–639.
  • Grangé JD, Amiot X. Nitric oxide and renal function in cirrhotic patients with ascites: from physiopathology. Eur J Gastroenterol Hepatol. 2004;16:567–570.
  • Kirkham P. Oxidative stress and macrophage function: a failure to resolve the inflammatory response. Biochm Soc Trans. 2007;35:284–287.
  • Arteel E. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterol. 2000;124:778–790.
  • Czezot H, Scibior D, Skrzycki M, et al. Glutathione and GSH-dependent enzymes in patients with liver cirrhosis and hepatocellular carcinoma. Acta Biochim Pol. 2006;53:237–242.
  • Fortune1 B, Cardenas A. Ascites, refractory ascites and hyponatremia in cirrhosis. Gastroenterol Rep. 2017;5: 104–112.
  • Colle I, Durand F, Pessione F, et al. Clinical course, predictive factors and prognosis in patients with cirrhosis and type 1 hepatorenal syndrome treated with Terlipressin: a retrospective analysis. J Gastroenterol Hepatol. 2002;17:882–888.
  • Arroyo V, Ginès P, Gerbes AL, et al. Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club. Hepatology. 1996;23(1):164–176.
  • Barreto R, Fagundes C, Guevara M, et al. Type-1 hepatorenal syndrome associated with infections in cirrhosis: natural history, outcome of kidney function, and survival. Hepatology. 2014;59:1505–1513.
  • Salerno F, Monti V. Hepatorenal syndrome type 1 and bacterial infection: a catastrophic association in patients with cirrhosis. Hepatology. 2014;59: 1239–1241.
  • Locatelli F, Canaud B, Eckardt U, et al. Oxidative stress in end-stage renal disease: an emerging threat to patient outcome. Nephrol Dial Transplant. 2003;18: 1272–1280.
  • Marta R, Rosa N, Luís M, et al. Evaluation of oxidative stress biomarkers in patients with chronic renal failure: a case control study. BMC Res Notes. 2010;3:20.
  • Fialova L, Malbohan I, Kalousova M, et al. Oxidative stress and inflammation in pregnancy. Scand J Clin Lab Invest. 2006;66:121–127.
  • Lu Y, Cederbaum I. CYP2E1 potentiation of LPS and TNFalpha-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction. Genes Nutr. 2010;2:149–167.
  • Woods A, Davies J. Fragmentation of extracellular matrix by hypochlorous acid. Biochem J. 2003;376: 219–227.
  • Branden V, Verelst R, Vamecq J, et al. Effect of vitamin E on antioxidant enzymes, lipid peroxidation products and glomerulosclerosis in the rat remnant kidney. Nephron. 1997;76:77–81.
  • Ferri C, Croce G, Cofini V, et al. C-reactive protein: interaction with the vascular endothelium and possible role in human atherosclerosis. Curr Pharm Des. 2007;13:1631–1645.
  • Memon A, Staprans I, Noor M, et al. Infection and inflammation induce LDL oxidation in vivo. Arterioscler Thromb Vasc Biol. 2000;20:1536–1542.
  • Hamilton T, Asatryan L, Nilsen T, et al. LDL protein nitration: implication for LDL protein unfolding. Arch Biochem Biophys. 2008;1:1–14.
  • Islam N, O’Byrne D, Devaraj S, et al. Alpha-tocopherol supplementation decreases the oxidative susceptibility of LDL in renal failure patients on dialysis therapy. Atherosclerosis. 2000;150:217–224.
  • Ottaviano G, Tang S, Handy E, et al. Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPX-3) in mammalian cells. Mol Cell Biochem. 2009;327:111–126.
  • Cortes-Rojo C, Calderon-Cortes E, Clemente-Guerrero M, et al. Elucidation of the effects of lipoperoxidation on the mitochondrial electron transport chain using yeast mitochondria with manipulated fatty acid content. J Bioenerg Biomembr. 2009;41:15–28.
  • Granata S, Zaza G, Simone S, et al. Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease. BMC Genomics. 2009;10:388.
  • Galkina I, Dormeneva V, Bachschmid M, et al. Endothelium-leukocyte interactions under the influence of the superoxide-nitrogen monoxide system. Med Sci Monit. 2004;10:307–316.
  • Closs I, Basha Z, Habermeier A, et al. Interference of L-arginine analogues with L-arginine transport mediated by the y + carrier hCAT-2B. Nitric Oxide. 1997;1:65–73.
  • Tojo A, Welch J, Bremer V, et al. Colocalization of demethylating enzymes and NOS and functional effects of methylarginines in rat kidney. Kidney Int. 1997;52:1593–1601.
  • Ferraro B, Galli F, Frei B, et al. Peroxynitrite-induced oxidation of plasma lipids is enhanced in stable hemodialysis patients. Kidney Int. 2003;6:2207–2211.
  • Oberg P, McMenamin E, Lucas L, et al. Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int. 2004;65:1009–1016.