747
Views
0
CrossRef citations to date
0
Altmetric
Acute Kidney Injury

Comprehensive analysis of cuproptosis-related genes in immune infiltration and development of a novel diagnostic model for acute kidney injury

&
Article: 2325035 | Received 29 Aug 2023, Accepted 25 Feb 2024, Published online: 27 Mar 2024

References

  • Khwaja A. KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract. 2012;120(4):1–11. doi: 10.1159/000339789.
  • Al-Jaghbeer M, Dealmeida D, Bilderback A, et al. Clinical decision support for in-hospital AKI. J Am Soc Nephrol. 2018;29(2):654–660. doi: 10.1681/ASN.2017070765.
  • Singbartl K, Kellum JA. AKI in the ICU: definition, epidemiology, risk stratification, and outcomes. Kidney Int. 2012;81(9):819–825. doi: 10.1038/ki.2011.339.
  • Hoste EA, Bagshaw SM, Bellomo R, et al. Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med. 2015;41(8):1411–1423. doi: 10.1007/s00134-015-3934-7.
  • Kellum JA, Romagnani P, Ashuntantang G, et al. Acute kidney injury. Nat Rev Dis Primers. 2021;7(1):52. doi: 10.1038/s41572-021-00284-z.
  • Odutayo A, Wong CX, Farkouh M, et al. AKI and long-term risk for cardiovascular events and mortality. J Am Soc Nephrol. 2017;28(1):377–387. doi: 10.1681/ASN.2016010105.
  • Lin X, Li J, Tan R, et al. Identification of hub genes associated with the development of acute kidney injury by weighted gene Co-expression network analysis. Kidney Blood Press Res. 2021;46(1):63–73. doi: 10.1159/000511661.
  • Ronco C, Bellomo R, Kellum JA. Acute kidney injury. Lancet. 2019;394(10212):1949–1964. doi: 10.1016/S0140-6736(19)32563-2.
  • Hoste E, Bihorac A, Al-Khafaji A, et al. Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study. Intensive Care Med. 2020;46(5):943–953. doi: 10.1007/s00134-019-05919-0.
  • Wen Y, Parikh CR. Current concepts and advances in biomarkers of acute kidney injury. Crit Rev Clin Lab Sci. 2021;58(5):354–368. doi: 10.1080/10408363.2021.1879000.
  • Xiao Z, Huang Q, Yang Y, et al. Emerging early diagnostic methods for acute kidney injury. Theranostics. 2022;12(6):2963–2986. doi: 10.7150/thno.71064.
  • Molinari L, Del Rio-Pertuz G, Smith A, et al. Utility of biomarkers for sepsis-associated acute kidney injury staging. JAMA Netw Open. 2022;5(5):e2212709. doi: 10.1001/jamanetworkopen.2022.12709.
  • Yu JT, Hu XW, Yang Q, et al. Insulin-like growth factor binding protein 7 promotes acute kidney injury by ­alleviating poly ADP ribose polymerase 1 degradation. Kidney Int. 2022;102(4):828–844. doi: 10.1016/j.kint.2022.05.026.
  • Kim BE, Nevitt T, Thiele DJ. Mechanisms for copper acquisition, distribution and regulation. Nat Chem Biol. 2008;4(3):176–185. doi: 10.1038/nchembio.72.
  • Tsvetkov P, Coy S, Petrova B, et al. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science. 2022;375(6586):1254–1261. doi: 10.1126/science.abf0529.
  • Duan WJ, He RR. Cuproptosis: copper-induced regulated cell death. Sci China Life Sci. 2022;65(8):1680–1682. doi: 10.1007/s11427-022-2106-6.
  • Linkermann A, Chen G, Dong G, et al. Regulated cell death in AKI. J Am Soc Nephrol. 2014;25(12):2689–2701. doi: 10.1681/ASN.2014030262.
  • Hu Z, Zhang H, Yang SK, et al. Emerging role of ferroptosis in acute kidney injury. Oxid Med Cell Longev. 2019;2019:8010614–8010618. doi: 10.1155/2019/8010614.
  • Li N, Wang Y, Wang X, et al. Pathway network of pyroptosis and its potential inhibitors in acute kidney injury. Pharmacol Res. 2022;175:106033. doi: 10.1016/j.phrs.2021.106033.
  • Belavgeni A, Meyer C, Stumpf J, et al. Ferroptosis and necroptosis in the kidney. Cell Chem Biol. 2020;27(4):448–462. doi: 10.1016/j.chembiol.2020.03.016.
  • Famulski KS, de Freitas DG, Kreepala C, et al. Molecular phenotypes of acute kidney injury in kidney transplants. J Am Soc Nephrol. 2012;23(5):948–958. doi: 10.1681/ASN.2011090887.
  • Janosevic D, Myslinski J, McCarthy TW, et al. The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline. Elife. 2021;10:e62270. doi: 10.7554/eLife.62270.
  • Ritchie ME, Phipson B, Wu D, et al. Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 2015;43(7):e47–e47. doi: 10.1093/nar/gkv007.
  • Gu Z, Gu L, Eils R, et al. Circlize implements and enhances circular visualization in R. Bioinformatics. 2014;30(19):2811–2812. doi: 10.1093/bioinformatics/btu393.
  • Yu G, Wang LG, Han Y, et al. clusterProfiler: an R package for comparing biological themes among gene ­clusters. OMICS. 2012;16(5):284–287. doi: 10.1089/omi.2011.0118.
  • Yao W, Chen Y, Li Z, et al. Single cell RNA sequencing identifies a unique inflammatory macrophage subset as a druggable target for alleviating acute kidney injury. Adv Sci (Weinh). 2022;9(12):e2103675.
  • Singbartl K, Formeck CL, Kellum JA. Kidney-immune system crosstalk in AKI. Semin Nephrol. 2019;39(1):96–106. doi: 10.1016/j.semnephrol.2018.10.007.
  • Uchida T, Yamada M, Inoue D, et al. Involvement of innate immune system in the pathogenesis of sepsis-associated acute kidney injury. Int J Mol Sci. 2023;24(15):12465. doi: 10.3390/ijms241512465.
  • Anders HJ, Wilkens L, Schraml B, et al. One concept does not fit all: the immune system in different forms of acute kidney injury. Nephrol Dial Transplant. 2021;36(1):29–38. doi: 10.1093/ndt/gfaa056.
  • Zheng L, Gao W, Hu C, et al. Immune cells in ischemic acute kidney injury. Curr Protein Pept Sci. 2019;20(8):770–776. doi: 10.2174/1389203720666190507102529.
  • Ysebaert DK, De Greef KE, Vercauteren SR, et al. Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury. Nephrol Dial Transplant. 2000;15(10):1562–1574. doi: 10.1093/ndt/15.10.1562.
  • Huen SC, Cantley LG. Macrophage-mediated injury and repair after ischemic kidney injury. Pediatr Nephrol. 2015;30(2):199–209. doi: 10.1007/s00467-013-2726-y.
  • Okabe Y, Medzhitov R. Tissue biology perspective on macrophages. Nat Immunol. 2016;17(1):9–17. doi: 10.1038/ni.3320.
  • Okubo K, Kurosawa M, Kamiya M, et al. Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury. Nat Med. 2018;24(2):232–238. doi: 10.1038/nm.4462.
  • Huang W, Wang BO, Hou YF, et al. JAML promotes acute kidney injury mainly through a macrophage-dependent mechanism. JCI Insight. 2022;7(14):e158571. doi: 10.1172/jci.insight.158571.
  • Privratsky JR, Ide S, Chen Y, et al. A macrophage-endothelial immunoregulatory axis ameliorates septic acute kidney injury. Kidney Int. 2023;103(3):514–528. doi: 10.1016/j.kint.2022.10.008.
  • Noel S, Lee K, Gharaie S, et al. Immune checkpoint molecule TIGIT regulates kidney T cell functions and contributes to AKI. J Am Soc Nephrol. 2023;34(5):755–771. doi: 10.1681/ASN.0000000000000063.
  • Gong J, Noel S, Hsu J, et al. TCR(+)CD4(-)CD8(-) (double negative) T cells protect from cisplatin-induced renal epithelial cell apoptosis and acute kidney injury. Am J Physiol Renal Physiol. 2020;318(6):F1500–F1512. doi: 10.1152/ajprenal.00033.2020.
  • Sun J, Zhang J, Tian J, et al. Mitochondria in sepsis-induced AKI. J Am Soc Nephrol. 2019;30(7):1151–1161. doi: 10.1681/ASN.2018111126.
  • Nakagawa S, Nishihara K, Inui K, et al. Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury. Eur J Pharmacol. 2012;696(1-3):143–154. doi: 10.1016/j.ejphar.2012.09.010.
  • Su L, Zhang J, Gomez H, et al. Mitochondria ROS and mitophagy in acute kidney injury. Autophagy. 2023;19(2):401–414. doi: 10.1080/15548627.2022.2084862.
  • Li SR, Bu LL, Cai L. Cuproptosis: lipoylated TCA cycle proteins-mediated novel cell death pathway. Signal Transduct Target Ther. 2022;7(1):158. doi: 10.1038/s41392-022-01014-x.
  • Lau A, Rahn JJ, Chappellaz M, et al. Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury. Sci Adv. 2022;8(5):eabm0142. doi: 10.1126/sciadv.abm0142.
  • Tsuji N, Tsuji T, Yamashita T, et al. BAM15 treats mouse sepsis and kidney injury, linking mortality, mitochondrial DNA, tubule damage, and neutrophils. J Clin Invest. 2023;133(7):e152401. doi: 10.1172/JCI152401.
  • Tadagavadi R, Reeves WB. Neutrophils in cisplatin AKI-mediator or marker? Kidney Int. 2017;92(1):11–13. doi: 10.1016/j.kint.2017.03.023.
  • Liu Z, Li Z, Chen Z, et al. Numb ameliorates necrosis and inflammation in acute kidney injury induced by cisplatin. Chem Biol Interact. 2020;330:109251. doi: 10.1016/j.cbi.2020.109251.
  • Summers SA, Chan J, Gan PY, et al. Mast cells mediate acute kidney injury through the production of TNF. J Am Soc Nephrol. 2011;22(12):2226–2236. doi: 10.1681/ASN.2011020182.