Transferrin levels are associated with malnutrition markers in hemodialysis patients in KwaZulu-Natal, South Africa

References

• Iorember FM. Malnutrition in chronic kidney disease [mini review]. Front Pediatr. 2018;6:1. doi:10.3389/fped.2018.00161.
   PubMed Web of Science ®Google Scholar
• Martin-Alemañy G, Valdez-Ortiz R, Olvera-Soto G, et al. The effects of resistance exercise and oral nutritional supplementation during hemodialysis on indicators of nutritional status and quality of life. Nephrol Dial Transplant. 2016;31(10):1712–9. doi:10.1093/ndt/gfw297.
   PubMed Web of Science ®Google Scholar
• Dai L, Mukai H, Lindholm B, et al. Clinical global assessment of nutritional status as predictor of mortality in chronic kidney disease patients. PLoS One. 2017;12(12):e0186659. doi:10.1371/journal.pone.0186659.
   PubMed Web of Science ®Google Scholar
• Detsky AS, McLaughlin JR, Baker JP, et al. What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr. 1987;11(1):8–13. Jan-Feb doi:10.1177/014860718701100108.
   PubMed Web of Science ®Google Scholar
• Serón-Arbeloa C, Labarta-Monzón L, Puzo-Foncillas J, et al. Malnutrition screening and assessment. Nutrients. 2022;14(12):2392–2401. Jun 9 doi:10.3390/nu14122392.
   PubMed Web of Science ®Google Scholar
• Tang AM, Chung M, Dong KR, et al. Determining a global mid-upper arm circumference cut-off to assess underweight in adults (men and non-pregnant women). Public Health Nutr. 2020;23(17):3104–3113. Dec doi:10.1017/S1368980020000397.
   PubMed Web of Science ®Google Scholar
• Tang AM, Dong K, Deitchler M, et al. Use of cutoffs for mid-upper arm circumference (MUAC) as an indicator or predictor of nutritional and health-related outcomes in adolescents and adults: a systematic review. Washington DC: Food and Nutrition Technical Assistance III Project (FANTA); 2013.
   Google Scholar
• Yang Y, Wu Y. The association between skinfold thicknesses and estimated glomerular filtration rate in adolescents: a cross-sectional study. BMC Nephrol. 2022;23(1):96. doi:10.1186/s12882-022-02709-7.
   PubMed Web of Science ®Google Scholar
• Addo OY, Himes JH, Zemel BS. Reference ranges for midupper arm circumference, upper arm muscle area, and upper arm fat area in US children and adolescents aged 1–20 y. Am J Clin Nutr. 2016;105(1):111–120. doi:10.3945/ajcn.116.142190.
   PubMed Web of Science ®Google Scholar
• Ogun AS, Adeyinka A. Biochemistry, transferrin. StatPearls. Treasure Island (FL): StatPearls Publishing, Copyright © 2022, StatPearls Publishing LLC.; 2022.
   Google Scholar
• Bermejo F, García-López S. A guide to diagnosis of iron deficiency and iron deficiency anemia in digestive diseases. World J Gastroenterol. 2009; Oct 715(37):4638–4643. doi:10.3748/wjg.15.4638.
   PubMed Web of Science ®Google Scholar
• Levitt DG, Levitt MD. Human serum albumin homeostasis: a new look at the roles of synthesis, catabolism, renal and gastrointestinal excretion, and the clinical value of serum albumin measurements. Int J Gen Med. 2016;9:229–255. doi:10.2147/IJGM.S102819.
   PubMed Web of Science ®Google Scholar
• Keller U. Nutritional laboratory markers in malnutrition. J Clin Med. 2019;8(6):775.
   PubMed Web of Science ®Google Scholar
• Grüngreiff K, Gottstein T, Reinhold D, et al. Albumin substitution in decompensated liver cirrhosis: don’t forget zinc. Nutrients. 2021;13(11):4011. doi:10.3390/nu13114011.
   PubMed Web of Science ®Google Scholar
• Kim B-J, Zhou J, Martin B, et al. Transferrin fusion technology: a novel approach to prolonging biological half-life of insulinotropic peptides. J Pharmacol Exp Ther. 2010;334(3):682–692. 05/01 doi:10.1124/jpet.110.166470.
   PubMed Web of Science ®Google Scholar
• Litchford MD. Chapter 8-nutritional issues in the patient with diabetes and foot ulcers. In: bowker JH, Pfeifer MA, editors. Levin and neal. The diabetic foot. (Seventh Edition). Philadelphia: Mosby; 2008. p. 199–217.
   Google Scholar
• Mackenzie EL, Iwasaki K, Tsuji Y. Intracellular iron transport and storage: from molecular mechanisms to health implications. Antioxid Redox Signal. 2008;10(6):997–1030. 2008/06/01 doi:10.1089/ars.2007.1893.
   PubMed Web of Science ®Google Scholar
• Siddiqui K, Rafiq M, Bhutto MA, et al. Red blood indices, platelet count and transferrin levels in celiac patients with and without type 1diabetes mellitus in Hyderabad Sindh. Pakistan. Khyber Med Univ J. 2021;13(1):25–29.
   Google Scholar
• Velaga RM. Elucidating the role of mitoferrin (mfrn), iron regulatory proteins (IRP1 and IRP2) and hephaestin (heph). In Iron metabolism by TagSNP and protein-protein interaction (PPI). Analysis: London Metropolitan University; 2014.
   Google Scholar
• Crowe A, Morgan EH. Iron and transferrrin uptake by brain and cerebrospinal fluid in the rat. Brain Res. 1992;592(1–2):8–16. doi:10.1016/0006-8993(92)91652-u.
   PubMed Web of Science ®Google Scholar
• Batchelor EK, Kapitsinou P, Pergola PE, et al. Iron deficiency in chronic kidney disease: updates on pathophysiology, diagnosis, and treatment. J Am Soc Nephrol. 2020;31(3):456–468. Mar doi:10.1681/ASN.2019020213.
   PubMed Web of Science ®Google Scholar
• Gutiérrez OM. Treatment of iron deficiency anemia in CKD and end-stage kidney disease. Kidney Int Rep. 2021; Sep6(9):2261–2269. doi:10.1016/j.ekir.2021.05.020.
   PubMed Web of Science ®Google Scholar
• Zhao L, Zou Y, Zhang J, et al. Serum transferrin predicts end-stage renal disease in type 2 diabetes mellitus patients. Int J Med Sci. 2020;17(14):2113–2124. doi:10.7150/ijms.46259.
   PubMed Web of Science ®Google Scholar
• Aguilera A, Bajo MA, Espinoza M, et al. Gastrointestinal and pancreatic function in peritoneal dialysis patients: their relationship with malnutrition and peritoneal membrane abnormalities. Am J Kidney Dis. 2003;42(4):787–796. doi:10.1016/s0272-6386(03)00920-x.
   PubMed Web of Science ®Google Scholar
• Saad MEN, Ragab U, Salah AM, et al. Study of nutritional status among end stage renal disease patients on regular hemodialysis in zagazig university hospitals. Egypt J Hosp Med. 2022;87(1):1407–1413. doi:10.21608/ejhm.2022.224890.
   Google Scholar
• Weekes C, Spiro A, Baldwin C, et al. A review of the evidence for the impact of improving nutritional care on nutritional and clinical outcomes and cost. J Hum Nutr Diet. 2009;22(4):324–335. doi:10.1111/j.1365-277X.2009.00971.x.
   PubMed Web of Science ®Google Scholar
• Gaweda AE. Markers of iron status in chronic kidney disease. Hemodial Int. 2017; Jun21 Suppl 1(Suppl 1):S21–s27. doi:10.1111/hdi.12556.
   PubMed Web of Science ®Google Scholar
• Patino E, Akchurin O. Erythropoiesis-independent effects of iron in chronic kidney disease [article. Pediatr Nephrol. 2022;37(4):777–788. doi:10.1007/s00467-021-05191-9.
   PubMed Web of Science ®Google Scholar
• Richard C, Verdier F. Transferrin receptors in erythropoiesis. Int J Mol Sci. 2020;21(24):9713. doi:10.3390/ijms21249713.
   PubMed Web of Science ®Google Scholar
• Del Vecchio L, Locatelli F. Clinical practice guidelines on iron therapy: a critical evaluation. Hemodial Int. 2017;21 Suppl 1(S1):S125–S131. doi:10.1111/hdi.12562.
   PubMedGoogle Scholar
• Martínez-Castelao A, Górriz JL, Segura-de la Morena J, et al. Consensus document for the detection and management of chronic kidney disease. Nefrologia. 2014;34(2):243–262.
   PubMed Web of Science ®Google Scholar
• Kuo IC, Lin HY, Niu SW, et al. Glycated hemoglobin and outcomes in patients with advanced diabetic chronic kidney disease. Sci Rep. 2016;6(1):20028. Jan 28 doi:10.1038/srep20028.
   PubMedGoogle Scholar
• Kalantar-Zadeh K, Kleiner M, Dunne E, et al. Total iron-binding capacity–estimated transferrin correlates with the nutritional subjective global assessment in hemodialysis patients. Am J Kidney Dis. 1998;31(2):263–272. doi:10.1053/ajkd.1998.v31.pm9469497.
   PubMed Web of Science ®Google Scholar
• Steiber AL, Kalantar-Zadeh K, Secker D, et al. Subjective global assessment in chronic kidney disease: a review. J Renal Nutr. 2004;14(4):191–200. doi:10.1016/S1051-2276(04)00139-6.
   PubMed Web of Science ®Google Scholar
• Woodruff B, Duffield A. Anthropometric assessment of nutritional status in adolescent populations in humanitarian emergencies. Eur J Clin Nutr. 2002;56(11):1108–1118. doi:10.1038/sj.ejcn.1601456.
   PubMed Web of Science ®Google Scholar
• Das A, Saimala G, Reddy N, et al. Mid-upper arm circumference as a substitute of the body mass index for assessment of nutritional status among adult and adolescent females: learning from an impoverished indian state. Public Health. 2020;179:68–75. Feb doi:10.1016/j.puhe.2019.09.010.
   PubMed Web of Science ®Google Scholar
• Musa IR, Omar SM, Adam I. Mid-upper arm circumference as a substitute for body mass index in the assessment of nutritional status among adults in Eastern Sudan. BMC Public Health. 2022;22(1):2056. 2022/11/10 doi:10.1186/s12889-022-14536-4.
   PubMed Web of Science ®Google Scholar
• Jones CH, Wolfenden RC, Wells LM. Is subjective global assessment a reliable measure of nutritional status in hemodialysis? J Ren Nutr. 2004;14(1):26–30. doi:10.1053/j.jrn.2003.09.006.
   PubMed Web of Science ®Google Scholar
• Rodrigues N, Sala P, Horie L, et al. Bioelectrical impedance analysis and skinfold thickness sum in assessing body fat mass of renal dialysis patients. J Ren Nutr. 2012;22(4):409–415.e2. 03/30 doi:10.1053/j.jrn.2012.01.024.
   PubMed Web of Science ®Google Scholar
• Sheikh RY, Samoon HJ, Bhat NA, et al. Malnutrition and inflammatory parameters in patients with chronic kidney disease stages 3–5 from Northern India. Egypt J Intern Med. 2022; 2022/09/1334(1):70. doi:10.1186/s43162-022-00149-1.
   Google Scholar
• Duong TV, Wu PY, Wong TC, et al. Mid-arm circumference, body fat, nutritional and inflammatory biomarkers, blood glucose, dialysis adequacy influence all-cause mortality in hemodialysis patients: a prospective cohort study. Medicine (Baltimore). 2019;98(12):e14930. Mar doi:10.1097/MD.0000000000014930.
   PubMed Web of Science ®Google Scholar
• Guenzani D, Buoli M, Caldiroli L, et al. Malnutrition and inflammation are associated with severity of depressive and cognitive symptoms of old patients affected by chronic kidney disease. J Psychosom Res. 2019; 2019/09/01/124:109783. doi:10.1016/j.jpsychores.2019.109783.
   PubMed Web of Science ®Google Scholar
• Bramania P, Ruggajo P, Bramania R, et al. Nutritional status of patients on maintenance hemodialysis at muhimbili national hospital in Dar Es Salaam, tanzania: a Cross-Sectional study. J Nutr Metab. 2021;2021:6672185–6672187. doi:10.1155/2021/6672185.
   PubMed Web of Science ®Google Scholar
• Bhattacharjee K, Das D, Rabha P, et al. A study on hematological profile in patients of chronic renal failure with special reference to serum iron profile. JEBMH. 2015;2(46):8212–8219. doi:10.18410/jebmh/2015/1107.
   Google Scholar
• Roy LG, Manjunath S, Urooj A, Department of Studies in Food Science and Nutrition, University of Mysore, Mysore, India. Screening of malnutrition using clinical, dietary and anthropometric variables in an indian hemodialysis population. JMED. 2015;2015:1–14. doi:10.5171/2015.847823.
   Google Scholar
• Ooi BS, Darocy A, Pollak V. Serum transferrin levels in chronic renal failure. Nephron. 1972;9(4):200–207. doi:10.1159/000180151.
   PubMed Web of Science ®Google Scholar
• Abdelaleem NE, Elsaeed W, Abdelfatah M. Evaluation of serum transferrin receptor level in children undergoing regular hemodialysis. Egypt J Hosp Med. 2022;86(1):66–72. 2022-01-01;86:66-66-72. doi:10.21608/ejhm.2021.209981.
   Google Scholar
• Kwiatkowska E, Opara M, Kwiatkowski S, et al. Is transferrin saturation a useful marker of iron metabolism in patients with chronic kidney disease treated with hemodialysis? TOUNJ. 2019;12(1):77–82. doi:10.2174/1874303X01912010077.
   Google Scholar
• Cross MB, Yi PH, Thomas CF, et al. Evaluation of malnutrition in orthopaedic surgery. J Am Acad Orthop Surg. 2014;22(3):193–199. doi:10.5435/JAAOS-22-03-193.
   PubMed Web of Science ®Google Scholar
• Worwood M, May AM, Bain BJ. Iron deficiency anaemia and iron overload. Dacie Lewis Pract Haematol. 2016;(12):165–186.
   Google Scholar
• Kuragano T, Joki N, Hase H, et al. Low transferrin saturation (TSAT) and high ferritin levels are significant predictors for cerebrovascular and cardiovascular disease and death in maintenance hemodialysis patients. PLoS One. 2020;15(9):e0236277. doi:10.1371/journal.pone.0236277.
   PubMed Web of Science ®Google Scholar
• Majeed A, Hameed A, Aftab I, et al. Soluble serum transferrin receptor (STFR) levels in hemodialysis patients. Annals KEMU. 2016;22(4):290–295. doi:10.21649/akemu.v22i4.1463.
   Google Scholar
• Wells BJ, Mainous AG, 3rd, King DE, et al. The combined effect of transferrin saturation and low density lipoprotein on mortality. Fam Med. 2004;36(5):324–329. May
   PubMed Web of Science ®Google Scholar
• Gaweda AE, Bhat P, Maglinte GA, et al. TSAT is a better predictor than ferritin of hemoglobin response to epoetin alfa in US dialysis patients. Hemodial Int. 2014;18(1):38–46. Jan doi:10.1111/hdi.12078.
   PubMed Web of Science ®Google Scholar
• Besarab A, Drueke TB. The problem with transferrin saturation as an indicator of iron ‘sufficiency’ in chronic kidney disease. Nephrol Dial Transplant. 2021; Jul 2336(8):1377–1383. doi:10.1093/ndt/gfaa048.
   PubMed Web of Science ®Google Scholar
• Sahathevan S, Khor BH, Ng HM, et al. Understanding development of malnutrition in hemodialysis patients: a narrative review. Nutrients. 2020;12(10):3147. Oct 15 doi:10.3390/nu12103147.
   PubMed Web of Science ®Google Scholar