Gender, Age and Microbial Status Influence upon Intestinal Cell Kinetics in a Compartmentalized Manner: An Experimental Study in Germfree and Conventional Rats

References

• Falk PG, Hooper LV, Midtvedt T, Gordon JI. Creating and maintaining the gastrointestinal ecosystem: what we know and need to know from gnotobiology. Microbiol Mol Biol Rev 1998; 62 (4): 1157–70.
   PubMed Web of Science ®Google Scholar
• Midtvedt T, Bjorneklett A, Carlstedt-Duke B, Gustafsson BE, et al. The influence of antibiotics upon microflora-associated characteristics in man and mammals. In: Wostmann BS, Pleasants JR, Pollard M, et al., eds Germfree Research Microflora Control and its Application to the Biomedical Sciences. New York: Alan R Liss Inc, 1985: 241–4.
   Google Scholar
• Midtvedt T. Microbial functional activities. Probiotics, other nutritional factors, and intestinal microflora. Nestle Nutrition Workshop Series 1999; 42: 79–96.
   Google Scholar
• Gordon HA, Pesti L. The gnotobiotic animal as a tool in the study of host microbial relationships. Bacteriological Reviews 1971; 35 (4): 390–429.
   Google Scholar
• Hageman RF, Sigdestad CP, Lesher S. A quantitative de-scription of the intestinal epithelium of the mouse. Am J Anat 1970; 1 (29): 41–51.
   Google Scholar
• Abrams GD, Bauer H, Sprinz H. Influence of the normal flora on mucosal morphology and cellular renewal in the ileum. Lab Invest 1963; 12: 355–64.
   Google Scholar
• Adam M, Midtvedt T, Uribe A. Differential cell kinetics in the ileum and colon of germfree rats. Scand J Gastroentrol 1994; 29: 445–51.
   Google Scholar
• Clark RM. Diet, mucosal architecture and epithelial cell production in the small intestine of specified-pathogen-free and conventional rats. Lab Animal 1975; 9: 201–9.
   Google Scholar
• Festing MFW. International Index of Laboratory Animals. Festing MFW, Leicester, England, 1993.
   Google Scholar
• Gustafsson BE. Lightweight stainless steel systems for rearing germfree animals. NY Acad Sci 1959; 78: 17–28.
   PubMed Web of Science ®Google Scholar
• Tannock IF. A comparison of the relative efficiencies of various metaphase arrest agents. Exp Cell Res 1965; 47: 345–56.
   Web of Science ®Google Scholar
• Wright NA, Morley A, Appleton D. Variation in the duration of mitosis in the crypt of Lieberkiihn of the rat; a cytokinetic study using vincristine. Cell Tissue Kinet 1972; 5: 351–64.
   Google Scholar
• Uribe A, Johansson C. Initial cell kinetic changes of prostaglandin E2-induced hyperplasia of the rat small intesti-nal epithelium occur in the villus compartments. Gastroen-terology 1988; 94: 1335–42.
   PubMed Web of Science ®Google Scholar
• Cleaver JE. Population kinetics in animal tissues. In: Thymidine Metabolism and Cell Kinetics. Amsterdam: North Holland, 1967: 184–234.
   Google Scholar
• Zylan KD, Brown SD. Effect of stress and food variety on food intake in male and female rats. Physiol Behav 1996; 59 (1): 165–9.
   Google Scholar
• Strohmayer AJ, Greenberg D. Devazepide increases food intake in male but not female Zucker rats. Physiol Behav 1996; 60 (1): 273–5.
   Web of Science ®Google Scholar
• Wostmann BS, Snyder DL, Pollard M. The diet-restricted rat as a model in aging studies. In: Ducluzeau R, ed Gnotobiol-ogy and its Application. Proceeding of the IX International Symposium on Gnotobiology. Lyon, France: Foundation Marcel Mériex, 1987: 57–9.
   Google Scholar
• Wright NA, Morley AR, Appleton D. The effect of testos-terone on cell proliferation and differentiation in the small bowel. J Endocr 1972; 52: 161–75.
   Google Scholar
• Tuohimaa P, Niemi M. The effect of testosterone on cell renewal and mitotic cycles in sex accessory glands of castrated mice. Acta Endocr 1968; 58 (4): 696–704.
   Google Scholar
• Snyder DL, Wostmann BS, Pollard M. Serum hormones in diet-restricted gnotobiotic and conventional Lobound-Wistar rats. J Gerontol 1988; 43 (6): B168–73.
   Google Scholar
• Eckstein B, Golan R, Shani J. Onset of puberty in the immature female rat induced by 5/7-androstane-3fi,17fl-diol. Endocrinology 1973; 92: 941–5.
   Google Scholar
• Fujita SH, Chiba M, Ohta M, Kitani K, Suzuki T. Alteration of plasma sex hormone levels associated with old age and its effect on hepatic drug metabolism in rats. J Pharm Exp Ther 1990; 253 (1): 369–74.
   Google Scholar
• Holt PR, Pascal RR, Koller DP. Effect of aging upon small intestinal structure in the Fischer rat. J Gerontol 1984; 39 (6): 642–7.
   Google Scholar
• O'Connor TM. Cell dynamics in the intestine of the mouse from late fetal life to maturity. Am J Anat 1966; 118 (2): 525–36.
   Google Scholar
• Gustafsson JA, Lisboa BP, Sjövall J. Studies on the metabolism of C19-steroids in rat liver. 3. Isolation and biosynthesis of 5/7-androstanetriols in rat liver microsomes. Eur J Biochem 1968; 6: 317–24.
   Google Scholar
• Gustafsson BE. Influence of the diet on the turnover of bile acids in germ-free and conventional rats. J Nutr 1969; 23: 429–42.
   Web of Science ®Google Scholar
• Olaya JH, Lorenz A, Uribe A. Mitogenic factor(s) of colonic bacteria stimulate DNA synthesis in a human colonic epithe-lial cell line. Microb Ecol Health Dis 1998; 10: 134–40.
   Google Scholar
• Koutsovelkidis I, Neopikhanov V, So derman C, Lorenz A, Uribe A. Butyrate inhibits and Escherichia coliderived mitogen(s) stimulate DNA synthesis in human hepatocytes in vitro. Prep Biochem Biotechnol 1999; 29 (2): 121–38.
   Google Scholar
• Osborne DL, Seidel ER. Microora-derived polyamines modulate obstruction-induced colonic mucosal hypertrophy. Am J Physiol 1989; 256: G1049–57.
   PubMedGoogle Scholar
• Young GP, Gibson PR. Butyrate and the colorectal cancer cell. In: Binder HJ, Gummings J, Soergel K, eds Short Chain Fatty Acids. Falk Symposium 73. Lancaster, UK: Kluwer Academic Publisher, 1994: 148–60.
   Google Scholar
• Casas JA, Edens FW, Dobrogosz WJ. Lactobacillus reuteri: an effective probiotic for poultry and other animals. In: Salminen S, von Wright A, eds Lactic Acid Bacteria, 2nd Edition. New York: Marcel Dekker Inc, 1998: 475–518.
   Google Scholar
• England JA, Watkins SE, Saleh E, Waldroup PW, Casas I, Burnham D. Effects of Lactobacillus reuteri on live performance and intestinal development of male turkeys. J Appl Poultr Res 1996; 5: 311–24.
   Web of Science ®Google Scholar
• Hall PA, Coates PJ, Ansari B, Hopwood D. Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 1994; 107: 3569–77.
   PubMed Web of Science ®Google Scholar
• Uribe A, Rubio C, Johansson C. Alternating proliferative capacity in the rat gastrointestinal mucosa. Scand J Gastroen-trol 1988; 23: 163–70.
   PubMed Web of Science ®Google Scholar
• Gordon HA, Bruckner-Kardoss E Effect of normal microbial flora on intestinal surface area. Am J Physiol 1961; 201: 175-8. Al-Dewachi HS, Wright NA, Appleton DR, Watson AL Studies on the mechanism of diurnal variation of proliferative indices in the small bowel mucosa of the rat. Cell Tissue Kinet 1976; 9: 459–67.
   Google Scholar
• Al-Dewachi HS, Wright NA, Appleton DR, Watson At The effect of starvation and refeeding on cell population kinetics in the rat small bowel mucosa. J Anat 1975; 119 (1): 105-21. Caimie AB, Bentley RE. Cell proliferation studies in the intestinal epithelium of the rat; hyperplasia during lactation. Exp Cell Res 1967; 46: 428–40.
   Google Scholar
• Al-Dewachi HS, Wright NA, Appleton DR, Watson AJ. The effect of starvation and refeeding on cell population kinetics in the rat small bowel mucosa. J Anat 1975; 119 (1): 105–21.
   Google Scholar
• Cairnie AB, Bentley RE. Cell proliferation studies in the intestinal epithelium of the rat; hyperplasia during lactation. Exp Cell Res 1967; 46: 428–40.
   PubMed Web of Science ®Google Scholar
• Uribe A, Alam M, Jaramillo E, Midtvedt T. Cell kinetics of the proximal jejunal epithelium in germfree rats. Microecology and Therapy 1990; 20: 377–82.
   Google Scholar
• Adam M, Midtvedt T, Uribe A. Differential cell kinetics in the ileum and colon of germfree rats. Scand J Gastroentrol 1994; 29: 445–51.
   Google Scholar
• Kwo-yih Y. Cell kinetics in the small intestine of suckling rats. 1. Influence of hypophysectomy. Anat Rec 1976; 188: 69–76.
   Google Scholar