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Original Paper

Dose-Dependent Preventive Effect of Saccharomyces boulardii on clindamycin-induced Alterations in Intestinal Aerobic Flora of the Hamster

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Pages 126-130 | Received 21 May 2003, Accepted 18 Aug 2003, Published online: 11 Jul 2009

REFERENCES

  • Klein SM, Elmer GW, McFarland LV, Surawicz CM, Levy RH. Recovery and elimination of the biotherapeutic agent, Sacchar-omyces boulardii, in healthy human volunteers. Pharm Res 1993; 10: 1615–9.
  • Surawicz CM, McFarland LV, Greenberg RN, Rubin M, Fekety R, Mulligan ME, Garcia RJ, Brandmarker S, Bowen K, Boijal D, Elmer GW. The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vanco-mycin combined with Saccharomyces boulardii. Clin Infect Dis 2000; 31: 1012–7.
  • Castagliuolo I, LaMont JT, Nikulasson ST, Pothoulakis C. Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum. Infect Immun 1996; 64: 5225–32.
  • Van der Waaij D, Hofstra H, Wiegersma N. Effect of 13-lactam antibiotics on the resistance of the digestive tract of mice to colonization. J Infect Dis 1982; 146: 417–22.
  • Orrhage K, Nord CE. Influences on the normal microbial flora. In: Elmer GW, McFarland LV, Surawicz CM, eds. Biother-apeutic Agents and Infectious Diseases. Totowa, NJ: Humana Press, 1999: 85–120.
  • Sambol SP, Merrigan MM, Tang JK, Johnson S, Gerding DN. Colonization for the prevention of Clostridium difficile disease in hamsters. J Infect Dis 2002; 186: 1781–9.
  • Toothaker RD, Elmer GW. Prevention of clindamycin induced mortality in hamsters by Saccharomyces boulardii. Antimicrob Agents Chemother 1984; 26: 552–6.
  • Lusk RH, Fekety R, Silva J, Browne RA, Ringler DH, Abrams GD. Clindamycin-induced enterocolitis in hamsters. J Infect Dis 1978; 137: 464–75.
  • Hagen CA, Shefner AM, Ehrlich R. Intestinal microfiora of normal hamsters. Lab Anim Care 1965; 15: 185–93.
  • Heimdahl A, Nord CE. Effect of erythromycin and clindamy-cin on the indigenous human anaerobic flora and new colonization of the gastrointestinal tract. Eur J Clin Microbiol 1982; 1: 38–48.
  • Pechere JC. Lincosamides. Pathol Biol (Paris) 1986; 34: 119–28.
  • Bartlett JG. Antibiotic-associated diarrhea. Clin Infect Dis 1992; 15: 573–7.
  • Surawicz CM, Elmer GW, Speelman P, McFarland LV, Chinn J, Van Belle G. Prevention of antibiotic-associated diarrhea by S. boulardii: a prospective study. Gastroenterology 1989; 96: 981–8.
  • Gedek BR. Adherence of Escherichia coli serogroup 0 157 and the Salmonella typhimurium mutant DT 104 to the surface of Saccharomyces boulardii. Mycoses 1999; 42: 261–4.
  • Tasteyre A, Barc MC, Karjalainen T, Bourlioux P, Collignon A. Inhibition of in vitro cell adherence of Clostridium difficile by Saccharomyces boulardii. Microb Pathog 2002; 32: 219–25.