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Original

The expression of collagenase 3 (MMP-13) mRNA in the synovial tissue is associated with histopathologic type II synovitis in rheumatoid arthritis

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Pages 307-313 | Published online: 07 Jul 2009

References

  • Krenn V, Morawietz L, Haupl T, Neidel J, Petersen I, Konig A. Grading of chronic synovitis—a histopathological grading system for molecular and diagnostic pathology. Pathol Res Pract 2002; 198: 317–325
  • Kruithof E, Baeten D, De Rycke L, Vandooren B, Foell D, Roth J, Canete JD, Boots AM, Veys EM, De Keyser F. Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis. Arthritis Res Ther 2005; 7: R569–R580
  • Fritz P, Laschner W, Saal JG, Deichsel G, Tuczek HV, Wegner G. Histological classification of synovitis. Zentralbl Allg Pathol 1989; 135: 729–741
  • Hitchon CA, el Gabalawy HS. The histopathology of early synovitis. Clin Exp Rheumatol 2003; 21(Suppl 31)S28–S36
  • Kraan MC, Haringman JJ, Ahern MJ, Breedveld FC, Smith MD, Tak PP. Quantification of the cell infiltrate in synovial tissue by digital image analysis. Rheumatology (Oxford) 2000; 39: 43–49
  • Kraan MC, Haringman JJ, Post WJ, Versendaal J, Breedveld FC, Tak PP. Immunohistological analysis of synovial tissue for differential diagnosis in early arthritis. Rheumatology (Oxford) 1999; 38: 1074–1080
  • Bresnihan B, Cunnane G, Youssef P, Yanni G, FitzGerald O, Mulherin D. Microscopic measurement of synovial membrane inflammation in rheumatoid arthritis: Proposals for the evaluation of tissue samples by quantitative analysis. Br J Rheumatol 1998; 37: 636–642
  • Ilgner S, Stiehl P. Strong LFA-1 and VCAM-1 expression in histological type II of rheumatoid arthritis. Cell Mol Biol (Noisy le grand) 2002; 48: OL243–OL249
  • Ruschpler P, Stiehl P. Shift in Th1 (IL-2 and IFN-gamma) and Th2 (IL-10 and IL-4) cytokine mRNA balance within two new histological main-types of rheumatoid-arthritis (RA). Cell Mol Biol (Noisy le grand) 2002; 48: 285–293
  • Stiehl P. Histologie der Rheumatoid Arthritis. Beitrag zur diagnostischen und pathogenetischen Heterogenität, zur Aktivitätsdiagnose und Prognose. Arthritiden, U Sack. Pabst Science Publ, Lengerich 1997; 188–200
  • Konttinen YT, Ainola M, Valleala H, Ma J, Ida H, Mandelin J, Kinne RW, Santavirta S, Sorsa T, Lopez-Otin C, Takagi M. Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: Different profiles in trauma and rheumatoid arthritis. Ann Rheum Dis 1999; 58: 691–697
  • Tetlow LC, Woolley DE. Comparative immunolocalization studies of collagenase 1 and collagenase 3 production in the rheumatoid lesion, and by human chondrocytes and synoviocytes in vitro. Br J Rheumatol 1998; 37: 64–70
  • Wernicke D, Seyfert C, Hinzmann B, GromnicaIhle E. Cloning of collagenase 3 from the synovial membrane and its expression in rheumatoid arthritis and osteoarthritis. J Rheumatol 1996; 23: 590–595
  • Hembry RM, Bagga MR, Reynolds JJ, Hamblen DL. Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis. Ann Rheum Dis 1995; 54: 25–32
  • Wolfe GC, MacNaul KL, Buechel FF, McDonnell J, Hoerrner LA, Lark MW, Moore VL, Hutchinson NI. Differential in vivo expression of collagenase messenger RNA in synovium and cartilage. Quantitative comparison with stromelysin messenger RNA levels in human rheumatoid arthritis and osteoarthritis patients and in two animal models of acute inflammatory arthritis. Arthritis Rheum 1993; 36: 1540–1547
  • Tetlow LC, Lees M, Ogata Y, Nagase H, Woolley DE. Differential expression of gelatinase B (MMP-9) and stromelysin-1 (MMP-3) by rheumatoid synovial cells in vitro and in vivo. Rheumatol Int 1993; 13: 53–59
  • Billinghurst RC, Dahlberg L, Ionescu M, Reiner A, Bourne R, Rorabeck C, Mitchell P, Hambor J, Diekmann O, Tschesche H, Chen J, VanWart H, Poole AR. Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage. J Clin Invest 1997; 99: 1534–1545
  • Knauper V, Lopez Otin C, Smith B, Knight G, Murphy G. Biochemical characterization of human collagenase 3. J Biol Chem 1996; 271: 1544–1550
  • Knauper V, Cowell S, Smith B, Lopez Otin C, O'Shea M, Morris H, Zardi L, Murphy G. The role of the C-terminal domain of human collagenase 3 (MMP-13) in the activation of procollagenase 3, substrate specificity, and tissue inhibitor of metalloproteinase interaction. J Biol Chem 1997; 272: 7608–7616
  • SchulzeWesthoff C, Freudiger D, Petrow P, Seyfert C, Zacher J, Kriegsmann J, Pap T, Gay S, Stiehl P, Gromnica-Ihle E, Wernicke D. Characterization of collagenase 3 (matrix metalloproteinase 13) messenger RNA expression in the synovial membrane and synovial fibroblasts of patients with rheumatoid arthritis. Arthritis Rheum 1999; 42: 1517–1527
  • Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315–324
  • Stiehl P, Keitel W, Becker R, Kuhn H. Differenzierte Synovialhistologie zur Charakterisierung einer möglichen Heterogenität und Prognose der Rheumatoid Arthritis. Zeitschrift für Rheumatologie 1998; 57(Suppl. 1)P5
  • Feldmann M, Brennan FM, Maini RN. Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 1996; 14: 397–440
  • Dinther-Janssen AC, Kraal G, van Soesbergen RM, Scheper RJ, Meijer CJ. Immunohistological and functional analysis of adhesion molecule expression in the rheumatoid synovial lining layer. Implications for synovial lining cell destruction. J Rheumatol 1994; 21: 1998–2004
  • Muller-Ladner U, Kriegsmann J, Franklin BN, Matsumoto S, Geiler T, Gay RE, Gay S. Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. Am J Pathol 1996; 149: 1607–1615
  • Petrow PK, Wernicke D, Schulze-Westhoff C, Hummel KM, Brauer R, Kriegsmann J, Gromnica-Ihle E, Gay RE, Gay S. Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis. Ann Rheum Dis 2002; 61: 391–397
  • Konttinen YT, Salo T, Hanemaaijer R, Valleala H, Sorsa T, Sutinen M, Ceponis A, Xu JW, Santavirta S, Teronen O, Lopez-Otin C. Collagenase 3 (MMP-13) and its activators in rheumatoid arthritis: Localization in the pannus-hard tissue junction and inhibition by alendronate. Matrix Biol 1999; 18: 401–412
  • Wernicke D, Schulze-Westhoff C, Petrow P, Brauer R, Zacher J, Gay S, Gromnica-Ihle E. Stimulation of collagenase 3 expression in synovial fibroblasts of patients with rheumatoid arthritis by contact with a three-dimensional collagen matrix or with normal cartilage when coimplanted in NOD/SCID mice. Arthritis Rheum 2002; 46: 64–74
  • Green MJ, Gough AK, Devlin J, Smith J, Astin P, Taylor D, Emery P. Serum MMP-3 and MMP-1 and progression of joint damage in early rheumatoid arthritis. Rheumatology (Oxford) 2003; 42: 83–88
  • Cunnane G, FitzGerald O, Hummel KM, Youssef PP, Gay RE, Gay S, Bresnihan B. Synovial tissue protease gene expression and joint erosions in early rheumatoid arthritis. Arthritis Rheum 2001; 44: 1744–1753
  • Kraan MC, Versendaal H, Jonker M, Bresnihan B, Post WJ, Hart BA, Breedveld FC, Tak PP. Asymptomatic synovitis precedes clinically manifest arthritis. Arthritis Rheum 1998; 41: 1481–1488
  • Tak PP, Smeets TJ, Daha MR, Kluin PM, Meijers KA, Brand R, Meinders AE, Breedveld FC. Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity. Arthritis Rheum 1997; 40: 217–225

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