Anti-nuscleosome antibody, a reliable indicator for lupus nephritis

References

• Van Holde KE. Chromatin. Springer series in molecular biology, A Rich. Springer, New York, NY 1989; 246
   Google Scholar
• Kávai M, Bányai A, Zsindely A, Sonkoly I, Szegedi G. An ensyme-linked immunosorbent asssay for autoantibodies to native DNA in sera patients with systemic lupus erythematosus. J Immunol Methods 1982; 48: 169–175
   PubMedGoogle Scholar
• Monier JC. Antinuclear antibodies: detection and diagnostic value. Int J Rad Appl Instrum B. 1990; 17: 713–718
   PubMedGoogle Scholar
• Lachman PJ. An attempt to characterize the lupus erythematosus cell antigen. Immunology 1961; 4: 153–163
   PubMedGoogle Scholar
• Amoura Z, Piette JC, Bach JF, Koutouzov S. The key role of nucleosomes in lupus. Arthritis Rheum 1999; 42: 833–843
   PubMedGoogle Scholar
• Burlingame RW, Boey ML, Starkebaum G, Rubin RL. The central role of chromatin in autoimune responses to histones and DNA in systemic lupus erythematosus. J Clin Invest 1994; 94: 184–192
   PubMed Web of Science ®Google Scholar
• Amoura Z, Chabre H, Koutouzov S, Lotton C, Cabrespines A, Bach JF, Jacob L. Nucleosome-restricted antibodies are detected before anti-dsDNA and/or antihistone antibodies in serum of MRL-Mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria. Arthritis Rheum 1994; 37: 1684–1688
   PubMedGoogle Scholar
• Desai-Mehta A, Mao C, Rajagopalan S, Robinson T, Datta SK. Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J Clin Invest 1995; 95: 531–541
   PubMed Web of Science ®Google Scholar
• Mohan C, Adams S, Stanik V, Datta SK. Nucleosome: A major target for pathogenic autoantibody-inducing T cells of lupus. J Exp Med 1993; 177: 1367–1381
   PubMed Web of Science ®Google Scholar
• Chabre H, Amoura Z, Piette JC, Godeau P, Bach JF, Koutouzov S. Presence of nucleosome-restricted antibodies in patients with systemic lupus erythematosus. Arthritis Rheum 1995; 38: 1485–1491
   PubMedGoogle Scholar
• Hochberg M. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997; 40: 1725–1743
   PubMed Web of Science ®Google Scholar
• Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH. Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum 1992; 3: 630–640
   Google Scholar
• Nagy G, Brózik M, Tornóci L, Gergely P. Diagnostic value of combined evaluation of neopterin and anti-DNA antibody levels for assessment of disease activity in systemic lupus erythematosus. Clin Exp Rheumatol 2000; 18: 699–705
   PubMedGoogle Scholar
• Abrass CK, Nies KM, Louie JS, Border WA, Glassock RJ. Correlation and predictive accuracy of circulating immune complexes with disease activity in patients with systemic lupus erythematosus. Arthritis Rheum 1980; 23: 273–282
   PubMedGoogle Scholar
• Foster MH, Cizman B, Madaio MP. Nephritogenic autoantibodies in systemic lupus erythematosus: Immunochemical properties, mechanisms of immune deposition, and genetic origins. Lab Invest 1993; 69: 494–507
   PubMedGoogle Scholar
• Lefkowith JB, Gilkeson GS. Nephritogenic antibodies in lupus: Current concepts and continuing controveresries. Arthritis Rheum 1996; 39: 894–903
   PubMed Web of Science ®Google Scholar
• Bernstein KA, Valerio RD, Lefkowith JB. Glomerular binding acivity in MRL lpr serum consists of antiboies that bind to a DNA/histone/type IV collagen complex. J Immunol 1995; 154: 2424–2433
   PubMedGoogle Scholar
• Fésűs L. Biochemical events in naturally occuring forms of cell death. FEBS Lett 1993; 328: 1–5
   PubMed Web of Science ®Google Scholar
• Strasser A, Huang DC, Vaux DL. The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy. Biochim Biophys Acta 1997; 1333: 151–178
   PubMed Web of Science ®Google Scholar
• Tax WJ, Kramers C, van Bruggen MC, Berden JH. Apoptosis, nucleosomes, and nephritis in systemic lupus erythematosus. Kidney Int 1995; 48: 666–673
   PubMedGoogle Scholar
• Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S. Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand. Cell 1994; 76: 969–976
   PubMed Web of Science ®Google Scholar
• Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992; 356: 314–317
   PubMed Web of Science ®Google Scholar
• Wu J, Wilson J, He J, Xiang L, Schur PH, Mountz JD. Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J Clin Invest 1996; 98: 1107–1113
   PubMed Web of Science ®Google Scholar
• Emlen W, Niebur J, Kadera R. Accelareted in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J Immunol 1994; 152: 3685–3692
   PubMed Web of Science ®Google Scholar
• Van Houten N, Budd RC. Accelerated programmed cell death of MRL-lpr/lpr T lymphoyctes. J Immunol 1992; 149: 2513–2517
   PubMed Web of Science ®Google Scholar
• Amoura Z, Pietta JC, Chabre H, Cacoub P, Papo T, Wechsler B, Bach JF, Koutouzov S. Circulating plasmalevels of nucleosomes in patients with systemic lupus erythematosus: correlation with serum anti-nulceosome antibody titers and absence of clear association with disease activity. Arthritis Rheum 1997; 40: 2217–2225
   PubMed Web of Science ®Google Scholar
• Savill J, Fadok V, Henson P, Haslett C. Phagocyte recognition of cells undergoing apoptosis. Immunol Today 1993; 14: 131–136
   PubMedGoogle Scholar
• Bell DA, Morrison B. The spontaneous apoptotic cell death of normal human lymphocytes in vitro: The release of, and immunproliferative response to, nucleosomes in vitro. Clin Immunol Immunpathol 1991; 60: 13–26
   PubMedGoogle Scholar
• Mevorach D, Zhou JL, Song X, Elkon KB. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J Exp Med 1998; 20: 387–392
   Google Scholar
• Herrmann M, Voll RE, Zoller OM, Hagenhofer M, Ponner BB, Kalden JR. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum 1998; 41: 1241–1250
   PubMed Web of Science ®Google Scholar
• Laderach D, Bach JF, Koutouzov S. Nucleosomes inhibit phagocytosis of apoptotic tymocytes by peritoneal macrophages from MRL+/+ lupus prone mice. J Leukoc Biol 1998; 64: 774–780
   PubMedGoogle Scholar
• Goetz J, Humbel RL. Antinucleosome antibodies. GET AI Info 1999; 1: 5–8
   Google Scholar
• Burlingame RW, Rubin RL. Subnucleosome structures as substrates in enzyme-linked immunosorbent assays. J Immunol Methods 1990; 134: 187–199
   PubMed Web of Science ®Google Scholar
• Monestier M. Autoantibodies to nucleosomes and histon/DNA complexes. Methods 1997; 11: 36–43
   PubMed Web of Science ®Google Scholar
• Rubin RL, Bell SA, Burlingame RW. Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex. J Clin Invest 1992; 90: 165–173
   PubMed Web of Science ®Google Scholar
• Amoura Z, Koutouzov S, Chabre H, Cacoub P, Amoura I, Musset L, Bach JF, Piette JC. Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases. Arthritis Rheum 2000; 43: 76–84
   PubMed Web of Science ®Google Scholar
• Gómez-Puerta JA, Burlingame RW, Cervera R. Anti-chromatin (anti-nucleosome) antibodies: Diagnostic and clinical value. Autoimmun Rev 2008; 7: 606–611
   PubMed Web of Science ®Google Scholar
• Tozzoli R. Recent advances in diagnostic technologies and their impact in autoimmune diseases. Autoimmun Rev 2007; 6: 334–340
   PubMed Web of Science ®Google Scholar
• Burlingame RW, Cervera R. Anti-chromatin (anti-nucleosome) autoantibodies. Autoimmun Rev 2002; 1: 321–328
   PubMedGoogle Scholar
• Muller S, Dieker J, Tincani A, Meroni PL. Pathogenic anti-nucleosome antibodies. Lupus 2008; 17: 431–436
   PubMed Web of Science ®Google Scholar