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Research Article

Aqueous Extract of Rhodiola imbricata Rhizome Stimulates Proinflammatory Mediators via Phosphorylated IκB and Transcription Factor Nuclear Factor-κB

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Pages 201-212 | Published online: 08 Oct 2008

REFERENCES

  • Engel L.W., Strauss S.E. Development of therapeutics: opportunities within complementary and alternative medicine. Nature Rev. Drug Discov 2002; 1: 229–237
  • Agarwal S.S., Singh V.K. Immunomodulators: a review of studies on Indian medicinal plants and synthetic peptides: Part I. Medicinal plants. Proc. Ind. Natl. Sc. Acad. 1999; 65: 179–204
  • Yamaguchi H. Immunomodulation by medicinal plants. Adv. Exp. Med. Biol 1992; 319: 287–297
  • Engler A. Syllabus der Pflanzenfamilien. Borntraeger, Berlin 1964; 2: 199–200
  • Saratikov A.S., Krasnov E.A. Rhodiola rosea is a valuable medicinal plant (Golden Root). Tomsk State University Press, Tomsk, Russia 1987
  • Kelly G. S. Rhodiola rosea: a possible plant adaptogen. Altern. Med. Rev 2001; 6: 293–302
  • Bocharova O.A., et al. The effect of a Rhodiola rosea extract on the incidence of recurrences of a superficial bladder cancer (experimental clinical research). Urol. Nefrol. (Mosk) 1995; 2: 46–47
  • Salikhova R.A., et al. Effect of Rhodiola rosea on the yield of mutation alteration and DNA repair in bone marrow cells. Patol. Fiziol. Exsp. Ter 1997; 4: 22–24
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983; 65: 55
  • Mehrotra S., Mishra K.P., Maurya R., Srimal R.C., Singh V.K. Immunomodulation by ethanolic extract of Boerhaavia diffusa. roots. Int. Immunopharmacol 2002; 2: 979–988
  • Narayan P., Singh V.K., Agarwal S.S., Tandon R., Haq W. Immunomodulation by opioid peptidomimetic compound. Neuroimmunomodulation 2000; 9: 134–140
  • Manna S.K., Mukhopadhyay A., Aggarwal B.B. Leflunomide suppresses TNF-induced cellular responses: effects on NF-κB, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis. J. Immunol 2000; 165: 5962
  • Beutler B., Cerami A. Tumor necrosis, cachexia shock, and inflammation: a common mediator. Ann. Rev. Biochem 1988; 57: 505–518
  • Jiang M.Z., Tsukahara H., Hayakawa K., Todoroki Y., Tamura S., Ohshima Y., Hiraoka M., Mayumi M. Effects of antioxidants and NO on TNF-alpha-induced adhesion molecule expression in human pulmonary microvascular endothelial cells. Respir. Med 2005; 99: 580–591
  • De Assis M.C., Saliba A.M., Vidipo L.A., De Salles J.B., Plotkowski M.C. Pseudomonas aeruginosa-induced production of free radicals by IFN gamma plus TNF alpha-activated human endothelial cells: mechanism of host defense or of bacterial pathogenesis?. Immunol. Cell. Biol 2004; 82: 383–392
  • Edwards C.K., Zhou T., Zhang J., Baker T.J., De M., Long R.E., Borcherding D.R., Bowlin T.L., Bluethmann H., Mountz T.D. Inhibition of super antigen induced proinflammatory cytokine production and inflammatory arthritis in MLR lpr/lpr mice by a transcriptional inhibitor of TNF-α. J. Immunol 1996; 157: 1758–1772
  • Rimbach G., Park Y.C., Guo Q., Moini H., Qureshi N., Saliou C., Takayama K., Virgili F., Packer L. Nitric oxide synthesis and TNF-alpha secretion in RAW 264.7 macrophages: mode of action of a fermented papaya preparation. Life Sci 2000; 30: 679–694
  • Saggio I., Ciapponi L., Savino R., Ciliberto G., Perricaudet M. Adenovirus- mediated gene transfer of a human IL-6 antagonist. Gene Therapy 1997; 4: 839–845
  • Okada M.M., Kitahara S., Kishimoto T., Matsuda T., Hirano T., Kishimoto T. IL-6/ BSF-2 functions as a killer helper factor in the in-vitro induction of cytotoxic T cells. J. Immunol 1988; 141: 1543–1549
  • Tracey K.J., Wei H., Nanogue K.R., Fong Y., Hesse D.G., Nguyen H.E., Kuo G.C., Beutler B., Cotran R.S., Cerami A., Lowry S.F. Cachectin/Tumor necrosis factor induces cachexia, anemia, and inflammation. J. Exp. Med 1998; 167: 1211–1227
  • Tracey K.J. Tumor necrosis factor (cachectin) in the biology of septic sock syndrome. Cir. Shock 1991; 35: 123–128
  • Glauser M.P. The inflammatory cytokines: new developments in the pathophysiology and treatment of septic shock. Drugs 1996; 52: 9–17
  • Dinarello C.A. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int. Rev. Immunol 1998; 16: 457–499
  • Shoda L.K., Palmer G.H., Florin-Christensen J., Florin-Christensen M., Godson D.L., Brown W.C. Babesia bovis-stimulated macrophages express interleukin-1beta, interleukin-12, tumor necrosis factor alpha, and nitric oxide and inhibit parasite replication in-vitro. Infect. Immun 5139–5134; 2000(68)5
  • Cook H.T., Cattell V. Role of nitric oxide in immune-mediated diseases. Clin. Sci. (London) 1996; 91: 375–384
  • Seo W.G., Pae H.O., Oh G.S., Kim N.Y., Kwon T.O., Shin M.K., Chai K.Y., Chung H.T. The aqueous extract of Rhodiola sachalinensis root enhances the expression of inducible nitric oxide synthase gene in RAW 264.7 macrophages. J. Ethnopharmacol 2001; 76: 119–123
  • Pae H.O., Seo W.G., Oh G.S., Kim N.Y., Kim Y.M., Kwon T.O., Shin M.K., Chai K.Y., Chung H.T. Rhodiola sachalinesis induces the expression of inducible nitric oxide synthase gene by murine fetal hepatocytes (BNL CL.2). Immunopharmacol. Immunotoxicol 2001; 23: 25–33
  • Mayer B., Hammens B. Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem. Sci 1997; 22: 477–481
  • Jeon Y.J., Kim Y.K., Lee M., Park S.M., Han S.B., Kim H.M. Radicicol suppresses expression of inducible nitric oxide synthase by blocking p38 kinase and nuclear factor-κB/Rel in lipopolysaccharide-stimulated macrophages. J. Pharmacol. Exp. Ther 2000; 294: 548–554
  • Zhou Y.Q., Chen Y.Q., Fisher J.H., Wang M.H. Activation of the RON receptor tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2 expression in murine macrophages. J. Biol. Chem 3810; 2002(277)4–38110
  • Wang T., Zhang X., Li J.J. The role of NF-κB in the regulation of cell stress responses. Int. J. Immunopharmacol 2002; 22: 1131–1135
  • Rininger J.A., Kickner S., Chigurupati P., McLean A., Franck Z. Immunopharmacological activity of Echinacea preparations following simulated digestion on murine macrophages and human peripheral blood mononuclear cells. J. Leukoc. Biol 2000; 68: 503–510

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