Immunoregulatory and Anti-Tumor Effects of Polysaccharopeptide and Astragalus polysaccharides on Tumor-Bearing Mice

REFERENCES

• Q.Y. Yang. 1997. Yun Zhi polysaccharopeptide (PSP) and the general aspects of its research. Fung. Sci. 12 (1,2):1–8.
   Google Scholar
• L.Q. Zhou, W.H. Koo, and P.T. Ang. 1996. Effect of polysaccharide-peptide (PSP), an extract from yun-zhi, on chemotherapy-induced cytopenias. Ann. Acad. Med. Singapore 25 (1):143–146.
   PubMedGoogle Scholar
• H.X. Wang, T.B. NG, W.K. Liu, V.E. Ooi, and S.T. Chang. 1996. Polysaccharide-peptide complexes from the cultured mycelia of the mushroom Coriolus versicolor and their culture medium activate mouse lymphocytes and macrophages. Int. J. Biochem. Cell. Biol. 28 (5):601–607.
   PubMedGoogle Scholar
• T.B. NG. 1998. A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: Polyporaceae). Gen. Pharmacol. 30 (1):1–4.
   PubMedGoogle Scholar
• F. Wu, and X. Chen. 2004. A review of pharmacological study on Astragalus membranaceus (Fisch) Bge. Zhong. Yao. Cai. 27 (3):232–234.
   PubMedGoogle Scholar
• Z.M. Qian, M.F. Xu, and P.L. Tang. 1997. Polysaccharide peptide (PSP) restores immunosuppression induced by cyclophosphamide in rats. Am. J. Chin. Med. 25 (1):27–35.
   PubMedGoogle Scholar
• G. Klein, and E. Klein. 1956. Conversion of solid neoplasms into ascites tumors. Ann. N. Y. Acad. Sci. 63 (5):640–661.
   PubMedGoogle Scholar
• J. Wang, L.L. Guo, and Y.Y. Wang. 2006. Study on combination components and effectiveness of Chinese traditional herbal formulas. Chin. J. of Chin. Materia. Medica. 31 (1):5–9.
   Google Scholar
• K.K. Chu, S.S. Ho, and A.H. C. Chow. 2002. Coriolus versicolor: a medicinal mushroom with promising immunotherapeutic values. J. Clin. Pharmacol. 42 (9):976–984.
   PubMedGoogle Scholar
• S.C. Jong, and X.T. Yang. PSP - A powerful biological response modifier from the mushroom Coriolus versicolor. In Q.Y. Yanged. International Symposium on Traditional Chinese Medicine and Cancer: Development and Clinical Validation — Advances in Research in PSP, Hong Kong Association for Health Care Ltd, 1999, pp. 16–28.
   Google Scholar
• Q.Y. Yang. Yun Zhi polysaccharopeptide (PSP) and the general aspects of its research. In Q.Y. Yanged. International Symposium on Traditional Chinese Medicine and Cancer: Development and Clinical Validation — Advances in Research in PSP, Hong Kong Association for Health Care Ltd, 1999, pp. 29–38.
   Google Scholar
• Y.L. Zhou, and Q.Y. Yang. Active principles from Coriolus sp. In Q.Y. Yanged. International Symposium on Traditional Chinese Medicine and Cancer: Development and Clinical Validation — Advances Research in PSP, Hong Kong Association for Health Care Ltd, 1999, pp. 111–124.
   Google Scholar
• Y.X. Bao, C.K. Wong, S.F Leung, A.T. Chan, P.W. Li, E.L. Wong, P.C Leung, K.P. Fung, Y.B. Yin, and C.W. Lam. 2006. Clinical Studies of immunomodulatory activities of Yunzhi-Danshen in patients with nasopharyngeal carcinoma. J. Altern. Complement. Med. 12 (8):771–776.
   PubMedGoogle Scholar
• C.K. Wong, Y.X. Bao, E.L. Wong, P.C. Leung, K.P. Fung, and C.W. Lam. 2005. Immunomodulatory activities of Yunzhi and Danshen in post-treatment breast cancer patients. Am. J. Chin. Med. 33 (3):381–395.
   PubMedGoogle Scholar
• Z.Q. Liang, X.X. Wang, Z.L. Gu, J.C. Yang, and W.H. Sheng. 1999. Effect of polysacchariopeptide on stimulation of IL-6 by human peripheral blood lymphocytes. Chin. J. of Pharm. 34 (10):700–702.
   Google Scholar
• W.K. Liu, T.B. Ng, S.F. Sze, and K.W. Tsui. 1993. Activation of peritoneal macrophages by polysaccharopeptide from the mushroom, C. VERSICOLOR. Immunopharmacology 26 (2):139–146.
   PubMedGoogle Scholar
• C.Y. Ho, C.B. Lau, C.F. Kim, K.N. Leung, K.P. Fung, T.F. Tse, H.H. Chan, and M.S. Chow. 2004. Differential effect of Coriolus versicolor (Yunzhi) extract on cytokine production by murine lymphocytes in vitro. Int. Immunopharmacol. 4 (12):1549–1457.
   PubMedGoogle Scholar
• K.W. Tsang, C.L. Lam, C. Yan, J.C. Mak, G.C. Ooi, J.C. Ho, B. Lam, R. Man, J.S. Sham, and W.K. Lam. 2003. Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell lung cancer. Respir. Med. 97 (6):618–624.
   PubMedGoogle Scholar
• M. Ryu, E.H. Kim, and M. Chun. 2007. Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk. J. Ethnopharmacol. [Epub ahead of print]
   PubMedGoogle Scholar
• X.Y. Cai, Y.L. Xu, and X.J. Lin. 2006. Effects of radix astragali injection on apoptosis of lymphocytes and immune function in patients with systemic lupus erythematosus. Zhongguo. Zhong. Xi. Yi. Jie. He. Za. Zhi. 26 (5):443–445.
   PubMedGoogle Scholar
• Y.S. Lee, O.K. Han, C.W. Park, C.H. Yang, T.W. Jeon, W.K. Yoo, S.H. Kim, and H.J. Kim. 2005. Pro-inflammatory cytokine gene expression and nitric oxide regulation of aqueous extracted Astragali radix in RAW 264.7 macrophage cells. J. Ethnopharmacol. 100 (3):289–294.
   PubMedGoogle Scholar
• Y.S. Lee, O.K. Han, C.W. Park, S.I. Suh, S.W. Shin, C.H. Yang, T.W. Jeon, E.S. Lee, K.J. Kim, S.H. Kim, W.K. Yoo, and H.J. Kim. 2003. Immunomodulatory effects of aqueous-extracted Astragali radix in methotrexate-treated mouse spleen cells. J. Ethnopharmacol. 84 (2–3):193–198.
   PubMedGoogle Scholar
• R. Jin, L.L. Wan, T. Mitsuishi, K. Kodama, and S. Kurashige. 1994. Immunomodulative effects of Chinese herbs in mice treated with anti-tumor agent cyclophosphamide. YakugakuZasshi 114 (7):533–538.
   PubMedGoogle Scholar
• B.M. Shao, W. Xu, H. Dai, P. Tu, Z. Li, and X.M. Gao. 2004. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochem. Biophys. Res. Commun. 320 (4):1103–1111.
   PubMedGoogle Scholar
• L. Weng, Y. Liu, X.Y. Liu, Y. Zhang, L.A. Zhao, and X.L. Deng. 2003. The effects of Astragalus polysaccharides sterile injection powder to the cytokine of mice spleen cells and the killing capability of natural killer cell. Chinese. Archives of Trad. Chin. Med. 21 (9):1522–1524.
   Google Scholar