Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 14, 2002 - Issue 2
103
Views
24
CrossRef citations to date
0
Altmetric
Research Article

PARTICULATE MATTER INFLAMMATION AND RECEPTOR SENSITIVITY ARE TARGET CELL SPECIFIC

, , &
Pages 159-183 | Published online: 01 Oct 2008

  • Adler, K. B., Fischer, B. M., Wright, D. T., Cohn, L. A., and Becker, S. 1994. Interactions between respiratory epithelial cells and cytokines: Relationships to lung inflammation. Ann. NY Acad. Sci. 725:128-145.
  • Amin, K., Ludviksdottir, D., Janson, C., Nettelbladt, O., Bjornsson, E., Roomans, G. M., Boman, G., Seveus, L., and Venge, P. 2000. Inflammation and structural changes in the airways of patients with atopic and nonatopicasthma. BHR Group. Am. J. Respir. Crit. Care Med. 162(6):2295-2301.
  • Antonini, J. M., Charron, T. G., Roberts, J. R., Lai, J., Blake, T. L., and Rogers, R. A. 1999. Application of laser scanning confocal microscopy in the analysis of particle-induced pulmonary fibrosis. Toxicol. Sci. 51(1):126-134.
  • Baccaglini, P. I., and Hogan, P. G. 1983. Some rat sensory neurons in culture express characteristics of differentiated pain sensory cells. Proc. Natl. Acad. Sci. USA 80(2):594-598.
  • Baeza-Squiban, A., Bonvallot, V., Boland, S., and Marano, F. 1999. Airborne particles evoke an inflammatory response in human airway epithelium. Activation of transcription factors. Cell Biol. Toxicol. 15 (6):3 75-380.
  • Baluk, P., Nadel, J. A., and McDonald, D. M. 1993. Calcitonin gene-related peptide in secretory granules of serous cells in the rat trachea! epithelium. Am. J. Respir. Cell Mol. Biol. 8(4):446-453.
  • Becker, S., Soukup, J. M., Gilmour, M. I., and Devlin, R. B. 1996. Stimulation of human and rat alveolar macrophages by urban air participates: Effects on oxidant radical generation and cytokine production. Toxicol. Appl. Pharmacol. 141(2):637-648.
  • Berridge, M. J. 1993. Inositol tri phosphate and calcium signalling. Nature 361:315-325.
  • Bevan, S., Hothi, S., Hughes, G., James, I. F., Rang, H. P., Shah, K., Walpole, C. S., and Yeats, J. C. 1992. Capsazepine: a competitive antagonist of the sensory neuron excitant capsaicin. Br. J. Pharmacol. 107(2):544-552.
  • Buist, A. S., Johnson, L. R., Vollmer, W. M., Sexton, G. J., and Kanarek, P. H. 1983. Acute effects of volcanic ash from Mount Saint Helens on lung function in children. Am. Rev. Respir. Dis. 127(6): 714-719.
  • Calderon-Garciduenas, L., Rodriguez-Alcaraz, A., Villarreal-Calderon, A., Lyght, O., Janszen, D., and Morgan, K. T. 1998. Nasal epithelium as a sentinel for airborne environmental pollution. Toxicol. Sci. 46(2):352-364.
  • Carter, J. D., Ghio, A. J., Samet, J. M., and Devlin, R. B. 1997. Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent. Toxicol. Appl. Pharmacol. 146(2):180-188.
  • Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., and Julius, D. 1997. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389(6653): 816-824.
  • Cater i na, M. J., Rosen, T. A., Tominaga, M., Brake, A. J., and Julius, D. 1999. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398(6726):436-441.
  • Caterina, M. J., Leffler, A., Malmberg, A. B., Martin, W. J., Trafton, J., Petersen-Zeitz, K. R., Koltzenburg, M., Basbaum, A. I., and Julius, D. 2000. Impaired nociception and pain sensation in mice lacking thecapsaicin receptor [see comments]. Science 288(5464):306-313.
  • Chan, K. Y., and Haschke, R. H. 1985. Specificity of a neuronotrophic factor from rabbit corneal epithelial cultures. Exp. Eye Res. 41 (6):687-699.
  • Chen, L. C, Miller, P. D., Amdur, M. O., and Gordon, T. 1992. Airway hyperresponsiveness in guinea pigs exposed to acid-coated ultrafine particles. J. Toxicol. Environ. Health 35(3):165174.
  • Chen, L. C, Qu, Q., Amdur, M. O., and Schlesinger, R. B. 1995. Alteration of pulmonary macrophage intracellular pH following inhalation exposure to sulfuric acid/ozone mixtures. Exp. Lung Res. 21(1):113-128.
  • Cohen, B. S., Xiong, J. Q., Fang, C. P., and Li, W. 1998. Deposition of charged particles on lung airways. Health Phys. 74(5):554-560.
  • Colquhoun, E. Q., Eldershaw, T. P., Bennett, K. L., Hall, J. L., Dora, K. A., and Clark, M. G. 1995. Functional and metabolic evidence for two different vanilloid (VR 1 and VR2) receptors in perfused rat hindlimb. Life Sci. 57(2):91-102.
  • Costa, D. L., and Dreher, K. L. 1997. Bioavailable transition metals in participate matter mediate cardiopulmonary injury in healthy and compromised animal models. Environ. Health Perspect. 105 (suppl.5):1053-1060.
  • Dalsgaard, C. J., and Lundberg, J. M. 1984. Evidence for a spinal afferent innervation of the guinea pig lower respiratory tract as studied by the horseradish peroxidase technique. Neurosci. Lett. 45(2):117-122.
  • Devalia, J. L., Bayram, H., Rusznak, C., Calderon, M., Sapsford, R. J., Abdelaziz, M. A., Wang, J., and Davies, R. J. 1997. Mechanisms of pollution-induced airway disease: In vitro studies in the upper and lower airways. Allergy 52(38 suppl.):45-51.
  • Di Maria, G. U., Bellofiore, S., and Geppetti, P. 1998. Regulation of airway neurogenic inflammation by neutral endopeptidase. fur. Respir. J. 12(6):1454-1462.
  • Dormans, J. A., Steerenberg, P. A., Arts, J. H., van Bree, L., de Klerk, A., Verlaan, A. P., Bruijntjes, J. P., Beekhof, P., van Soolingen, D., and Van Loveren, H. 1999. Pathological and immunological effects of respirable coal fly ash in male Wistar rats, lnhal. Toxicol. 11 (1):51-69.
  • Dye, J. A., Adler, K. B., Richards, J. H., and Dreher, K. L. 1997. Epithelial injury by exposure to residual oil fly-ash particles-Role of reactive oxygen species. Am. J. Respir. Cell Mol. Biol. 17(5): 625-633.
  • Elliott, W. M., and Auersperg, N. 1993. Comparison of the neutral red and methylene blue assays to study cell growth in culture. Biotech. Histochem. 68(1):29-35.
  • Elwood, W., Lotvall, J. O., Barnes, P. J., and Chung, K. F. 1993. Airway hyperresponsiveness to acetylcholine and to tachykinins after respiratory virus infection in the guinea pig. Ann. Allergy 70(3):231-236.
  • Evans, J. H., and Sanderson, M. J. 1999. Intracellular calcium oscillations induced by ATP in airway epithelial cells. Am. J. Physiol. 277(1 Pt 1):L30-L41.
  • Finger, T. E., St. Jeor, V. L., Kinnamon, J. C, and Silver, W. L. 1990. Ultrastructure of substan. J. Comp. Neurol. 294(2):293-305.
  • Fisher, G. L., McNeMI, K. L., Prentice, B. A., and McFarland, A. R. 1983. Physical and biological studies of coal and oil fly ash. Environ. Health Perspect. 51:181-186.
  • Folkerts, G., and Nijkamp, F. P. 1998. Airway epithelium: More than just a barrier Trends Pharmacol. Sci. 19(8):334-341.
  • Gardner, S. Y., Lehmann, J. R., and Costa, D. L. 2000. Oil fly ash-induced elevation of plasma fibrinogen levels in rats. Toxicol. Sci. 56(1) :175-180.
  • Carle, M. J., Knight, A., Downing, A. T., Jassi, K. L, Clothier, R. H., and Fry, J. R. 2000. Stimulation of dichlorofluorescin oxidation by capsaicin and analogues in RAW 264 monocyte/macrophages: Lack of involvement of the vanilloid receptor. Biochem. Pharmacol. 59(5):563-572.
  • Ghio, A. J., Stonehuerner, J., Pritchard, R., Piantadosi, C, Quigley, D. D. K., and Costa, D. 1996. Humic-like substances in air pollution particulates correlate with concentrations of transition metals and oxidant generation, lnhal. Toxicol. 8(479):494.
  • Gilks, C. B., Price, K., Wright, J. L., and Churg, A. 1998. Antioxidant gene expression in rat lung after exposure to cigarette smoke. Am. J. Pathol. 152(1):269-278.
  • Gold, M. S., Dastmalchi, S., and Levine, J. D. 1996. Co-expression of nociceptor properties in dorsal root ganglion neurons from the adult rat in vitro. Neuroscience 71 (1):265-275.
  • Goldsmith, C. A., Frevert, C., lmrich, A., Sioutas, C., and Kobzik, L. 1997. Alveolar macrophage interaction with air pollution particulates. Environ. Health Perspect. 105(suppl.5):1191-1195.
  • Gwynn, R. C., Burnett, R. T., and Thurston, G. D. 2000. A time-series analysis of acidic participate matter and daily mortality and morbidity in the Buffalo, New York, region. Environ. Health Perspect. 108(2):125-133.
  • Hamada, G. S., Kowalski, L. P., Murata, Y., Matsushita, H., and Matsuki, H. 1992. Wood stove effects on indoor air quality in Brazilian homes: Carcinogens, suspended participate matter, and nitrogen dioxide analysis. Tokai J. Exp. Clin. Med. 17(3-4): 145-153.
  • Hastings, R. H., and Hua, X. Y. 1995. Expression of calcitonin gene-related peptide by cultured rat alveolar type Il cells. Am. J. Respir. Cell Mol. Biol. 13(5):563-569.
  • Hatch, G. E., ed. 1992. Comparative biology of the normal lung. Boca Raton, FL: CRC Press.
  • Hatch, G. E., Boykin, E., Miller, F. J., and Graham, J. A. 1982. Effects of fly ash and its constituents on sensory irritation in mice. Fundam. Appl. Toxicol. 2(2):77-81.
  • Hess, S. D., Oortgiesen, M., and Cahalan, M. D. 1993. Calcium oscillations in human T and natural killer cells depend upon membrane potential and calcium influx. J. Immunol 150(7):2620- 2633.
  • Holroyde, M. C. 1986. The influence of epithelium on the responsiveness of guinea-pig isolated trachea. Br J. Pharmacol. 87(3):501-507.
  • Hoyle, G. W., Graham, R. M., Finkelstein, J. B., Nguyen, K. P., Gozal, D., and Friedman, M. 1998. Hyperinnervation of the airways in transgenic mice overexpressing nerve growth factor. Am. J. Respir. Cell Mol. Biol. 18(2):149-157.
  • Huggins, F. E., Huffman, G. P., and Robertson, J. D. 2000. Speciation of elements in NIST participate matter SRMs 1648 and 1650, J. Hazard. Mater. 74(1-2):1-23.
  • Hunter, D. D., and Undem, B. J. 1999. Identification and substance P content of vagal afferent neurons innervating the epithelium of the guinea pig trachea. Am. J. Respir. Crit. Care Med. 159(6):1943- 1948.
  • Jakab, G. J., Clarke, R. W., Hemenway, D. R., Longphre, M. V., Kleeberger, S. R., and Frank, R. 1996. Inhalation of acid coated carbon black particles impairs alveolar macrophage phagocytosis. Toxicol. Lett. 88(1-3):243-248.
  • Jiang, N., Dreher, K. L, Dye, J. A., Li, Y., Richards, J. H., Martin, L. D., and Adler, K. B. 2000. Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig trachea! epithelial cells via an oxidant-mediated mechanism. Toxicol. Appl. Pharmacol. 163(3):221-230.
  • Kimmel, T. A., Chen, L. C, Bosland, M. C., and Nadziejko, C. 1997. Influence of acid aerosol droplet size on structural changes in the rat lung caused by acute exposure to sulfuric acid and ozone. Toxicol. Appl. Pharmacol. 144(2):348-355.
  • Kinnula, V. L., Yankaskas, J. R., Chang, L., Virtanen, I., Linnala, A., Kang, B. H., and Crapo, J. D. 1994. Primary and immortalized (BEAS 2B) human bronchial epithelial cells have significant antioxidative capacity in vitro. Am. J. Respir. Cell Mol. Biol. 11 (5):568-576.
  • Kodavanti, U. P., Jaskot, R. H., Su, W. Y., Costa, D. L, Ghio, A. J., and Dreher, K. L 1997. Genetic variability in combustion particle-induced chronic lung injury. Am. J. Physiol. 272(3 Pt 1):L521- L532.
  • Kress, M., Reeh, P. W., and Vyklicky, L. 1997. An interaction of inflammatory mediators and protons in small diameter dorsal root ganglion neurons of the rat. Neurosci. Lett. 224(1)37-40.
  • Kummer, W., Fischer, A., Kurkowski, R., and Heym, C. 1992. The sensory and sympathetic innervation of guinea-pig lung and trachea as studied by retrograde neuronal tracing and doublelabelling immunohistochemistry. Neuroscience 49(3):715-737.
  • Ladenius, A. R., Folkerts, G., van der Linde, H. J., and Nijkamp, F. P. 1995. Potentiation by viral respiratory infection of ovalbumin-induced guinea- pig tracheal hyperresponsiveness: Role for tachykinins. Br. J. Pharmacol. 115(6):1048-1052.
  • Lambrichts, I., Creemers, J., and Van Steenberghe, D. 1993. Periodontal neural endings intimately relate to epithelial rests of Malassez in humans. A light and electron microscope study. J. Anat. 182(Pt2):153-162.
  • Lazarus, S. C. 1986. Role of inflammation and inflammatory mediators in airways disease. Am. J. Med. 81 (5A):2-7.
  • Li, X. Y., Gilmour, P. S., Donaldson, K., and MacNee, W. 1996. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax 51(12): 1216-1222.
  • Lies, K. H., Hartung, A., Postulka, A., Gring, H., and Schulze, J. 1986. Composition of diesel exhaust with particular reference to particle bound organics including formation of artifacts. Dev. Toxicol. Environ. Sci. 13:65-82.
  • Martin, T. R., Wehner, A. P., and Butler, J. 1983. Pulmonary toxicity of Mt. St. Helens volcanic ash. A review of experimental studies. Am. Rev. Respir. Dis. 128(1):158-162.
  • May, W. E., Benner, B. A. J., Wise, S. A., Schuetzle, D., and Lewtas, J. 1992. Standard reference materials for chemical and biological studies of complex environmental samples. Mutat. Res. 276 (1-2):11-22.
  • Miller, R. J. 1990. Receptor-mediated regulation of calcium channels and neurotransmitter release. FASEB J. 4(15):3291-3299.
  • Mills, P. R., Davies, R. J., and Devalia, J. L. 1999. Airway epithelial cells, cytokines, and pollutants. Am. J. Respir. Crit Care Med. 160(5 Pt 2):S38-S43.
  • Muallem, S., Zhao, H., Mayer, E., and Sachs, G. 1990. Regulation of intracellular calcium in epithelial cells. Semin. Cell Biol. 1(4):305-310.
  • Noah, T. L., Paradiso, A. M., Madden, M. C, McKinnon, K. P., and Devlin, R. B. 1991. The response of a human bronchial epithelial cell line to histamine: intracellular calcium changes and extracellular release of inflammatory mediators. Am. J. Respir. Cell Mol. Biol. 5(5):484-492.
  • Nordenhall, C., Pourazar, J., Blomberg, A., Levin, J. O., Sandstrom, T., and Adelroth, E. 2000. Airway inflammation following exposure to diesel exhaust: A study of time kinetics using induced sputum [In Process Citation], fur. Respir. J. 15(6):1046-1051.
  • Oberdörster, G., Ferin, J., and Morrow, P. E. 1992. Volumetric loading of alveolar macrophages (AM): A possible basis for diminished AM-mediated particle clearance. Exp. Lung Res. 18(1): 87-104.
  • Ogun-Muyiwa, P., Helliwell, R., Mclntyre, P., and Winter, J. 1999. GiaI cell line derived neurotrophic factor (GDNF) regulates VR1 and substance P in cultured sensory neurons. Neuroreport. 10(10):2107-2111.
  • Oortgiesen, M., Veronesi, B., Eichenbaum, G. M., and Simon, S. A. 2000. Residual oil fly ash (ROFA) and negatively charged synthetic polymers activate bronchial epithelial cells and nociceptive sensory neurons. Am. J. Physiol. Lung Cell. Mol. Physiol. 278(4):L683-L695.
  • Polito, A. J., and Proud, D. 1998. Epithelia cells as regulators of airway inflammation. J. Allergy Clin. lmmunol. 102(5):714-718.
  • Reddel, R. R., Ke, Y., Gerwin, B. I., McMenamin, M. G., Lechner, J. F., Su, R. T., Brash, D. E., Park, J. B., Rhim, J. S., and Harris, C. C. 1988. Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes. Cancer Res. 48(7):19041909.
  • Savela, K., Kohan, M. J., Walsh, D., Perera, F. P., Hemminki, K., and Lewtas, J. 1996. In vitro characterization of DNA adducts formed by foundry air particulate matter. Environ. Health Perspect. 104(suppl.3):687-690.
  • Savitha, G., Panchanathan, S., and Salimath, B. P. 1990. Capsaicin inhibits calmodulin-mediated oxidative burst in rat macrophages. Cell Signal. 2(6):577-585.
  • Schlesinger, R. B. 1995. Interaction of gaseous and particulate pollutants in the respiratory tract: Mechanisms and modulators. Toxicobgy 105(2-3):315-325.
  • Shu, X., and Mendell, L. M. 1999. Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin. Neurosci. Lett. 274(3):159-162.
  • Su, W. Y., Kodavanti, U. P., Jaskot, R. H., Costa, D. L, and Dreher, K. L. 1995. Temporal expression and cellular distribution of pulmonary fibronectin gene induction following exposure to an emission source particle. J. Environ. Pathol. Toxicol. Oncol. 14(3-4):215-225.
  • Szallasi, A. 1994. The vanilloid (capsaicin) receptor: receptor types and species differences. Gen. Pharmacol. 25(2):223-243.
  • Szallasi, A., and Blumberg, P. M. 1993. [3H]resiniferatoxin binding by the vanilloid receptor: Speciesrelated differences, effects of temperature and sulfhydryl reagents. Naunyn-Schmiedebergs Arch. Pharmacol. 347(1) :84-91.
  • Szallasi, A., and Blumberg, P. M. 1996. Vanilloid receptors: New insights enhance potential as a therapeutic target. Pain 68(2-3):195-208.
  • Szarek, J. L., Spurlock, B., Gruetter, C. A., and Lemke, S. 1998. Substance P and capsaicin release prostaglandin E2 from rat intrapulmonary bronchi. Am.). Physiol. 275(5 Pt 1):L1006-L1012.
  • Takizawa, H. 1998. Airway epithelial cells as regulators of airway inflammation. Int. J. Mol. Med. 1(2):367-378.
  • Veronesi, B., Oortgiesen, M., Carter, J. D., and Devlin, R. B. 1999a. Paniculate matter (PM) initiates inflammatory cytokine release by activation of capsaicin receptors in a human bronchial epithelial cell line. Toxicol. Appl. Pharmacol. 154(1) :106-115.
  • Veronesi, B., Carter, J. D., Devlin, R. B., Simon, S. A., and Oortgiesen, M. 1999b. Neuropeptides and capsaicin stimulate the release of proinflammatory cytokines in a human bronchial epithelial cell line. Neuropeptides 33(6):447-456.
  • Veronesi, B., Oortgiesen, M., Roy, J., Carter, J. D., Simon, S. A., and Gavett, S. H. 2000. Vanilloid (capsaicin) receptors influence inflammatory sensitivity in response to particulate matter. Toxicol. Appl. Pharmacol. 169:66-76.
  • Vincent, R., Bjarnason, S. G., Adamson, I. Y., Hedgecock, C., Kumarathasan, P., Guenette, J., Potvin, M., Goegan, P., and Bouthillier, L. 1997. Acute pulmonary toxicity of urban particulate matter and ozone. Am. J. Pathol. 151 (6):1563-1570.
  • Wasserman, S. 1.1988. Basic mechanisms in asthma. Ann. Allergy 60(5):477-482.
  • Wilson, W. E., and Suh, H. H. 1997. Fine particles and coarse particles: Concentration relationships relevant to epidemiologic studies. J. Air Waste Manage. Assoc. 47(12):1238-1249.
  • Wood, J. N., Winter, J., James, I. F., Rang, H. P., Yeats, J., and Bevan, S. 1988. Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture, j. Neurosci. 8(9):3208-3220.
  • Yano, E., Yokoyama, Y., Higashi, H., Nishii, S., Maeda, K., and Koizumi, A. 1990. Health effects of volcanic ash: A repeat study. Arch. Environ. Health 45(6):367-373.
  • Zhang, S. Z., Lipsky, M. M., Trump, B. F., and Hsu, I. C. 1990. Neutral red (NR) assay for cell viability and xenobiotic-induced cytotoxicity in primary cultures of human and rat hepatocytes. Cell Biol. Toxicol. 6(2):219-234.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.