Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 19, 2007 - Issue 4
328
Views
26
CrossRef citations to date
0
Altmetric
Research Article

Pulmonary Inflammation in Mice Exposed to Mainstream Cigarette Smoke

, , , , &
Pages 361-376 | Received 24 Jul 2006, Accepted 02 Nov 2006, Published online: 20 Oct 2008

REFERENCES

  • Aoshiba K., Tamaoki J., Nagai A. Acute cigarette smoke exposure induces apoptosis of alveolar macrophages. Am. J. Physiol. Lung Cell Mol. Physiol. 2001; 281: L1392–L1401
  • Aoshiba K., Yokohori N., Nagai A. Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am. J. Physiol. Lung Cell Mol. Physiol. 2003; 28: 555–562
  • Armstrong D. A., Major J. A., Chudyk A., Hamilton T. A. Neutrophil chemoattractant genes KC and MIP-2 are expressed in different cell populations at sites of surgical injury. J. Leukocyte Biol. 2004; 75: 641–648
  • Ayres P. H., Hayes J. R., Higuchi M. A., Mosberg A. T., Sagartz J. W. Subchronic inhalation by rats of mainstream smoke from a cigarette that primarily heats tobacco compared to a cigarette that burns tobacco. Inhal. Toxicol. 2001; 13: 149–186
  • Ballantyne E. R., Hill R. K., Spencer J. W. Probit analysis of thermal sensation assessments. Int. J. Biometeorol. 1977; 21: 29–43
  • Barnes P. J. Mediators of chronic obstructive pulmonary disease. Pharmacol. Rev. 2004; 56: 515–548
  • Bartalesi B., Cavarra E., Fineschi S., Lucattelli M., Lunghi B., Martorana P. A., Lungarella G. Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants. Eur. Respir. J. 2005; 25: 15–22
  • Cannon W., Blanton E., McDonald K. The flow-past chamber: An improved nose-only exposure system for rodents. Am. Ind. Hygiene Assoc. J. 1983; 44: 923–928
  • Cavarra E., Bartalesi B., Lucattelli M., Fineschi S., Lunghi B., Gambelli F., Ortiz L. A., Martorana P. A., Lungarella G. Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants. Am. J. Respir. Crit. Care Med. 2001a; 164: 886–890
  • Cavarra E., Lucattelli M., Gambelli F., Bartalesi B., Fineschi S., Szarka A., Giannerini F., Martorana P. A., Lungarella G. Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress. Am. J. Physiol. Lung Cell Mol. Physiol. 2001b; 281: L412–L417
  • Churg A., Dai J., Tai H., Xie C., Wright J. L. Tumor necrosis factor-alpha is central to acute cigarette smoke-induced inflammation and connective tissue breakdown. Am. J. Respir. Crit. Care Med. 2002; 166: 849–854
  • Coggins C. R., Duchosal F., Musy C., Ventrone R. Measurement of respiratory patterns in rodents using whole-body plethysmography and a pneumotachograph 2383. Lab. Anim. 1981; 15: 137–140
  • Coggins C. R., Ayres P. H., Mosberg A. T., Sagartz J. W., Burger G. T., Hayes A. W. Ninety-day inhalation study in rats, comparing smoke from cigarettes that heat tobacco with those that burn tobacco. Fundam. Appl. Toxicol. 1989; 13: 460–483
  • Cosio M. G., Majo J. Inflammation of the airways and lung parenchyma in COPD: Role of T cells. Chest 2002; 121: 160S–165S
  • Cosio Piqueras M. G., Cosio M. G. Disease of the airways in chronic obstructive pulmonary disease. Eur. Respir. J. Suppl. 2001; 34: 41s–49s
  • D'Agostini F., Balansky R. M., Izzotti A., Lubet R. A., Kelloff G. J., De Flora S. Modulation of apoptosis by cigarette smoke and cancer chemopreventive agents in the respiratory tract of rats. Carcinogenesis 2001; 22: 375–380
  • Dhami R., Gilks B., Xie C., Zay K., Wright J. L., Churg A. Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by alpha1-antitrypsin. Am. J. Respir. Cell Mol. Biol. 2000; 22: 244–252
  • Eidelman D., Saetta M. P., Ghezzo H., Wang N. S., Hoidal J. R., King M., Cosio M. G. Cellularity of the alveolar walls in smokers and its relation to alveolar destruction. Functional implications. Am. Rev. Respir. Dis. 1990; 141: 1547–1552
  • Ekberg-Jansson A., Andersson B., Bake B., Boijsen M., Enanden I., Rosengren A., Skoogh B. E., Tylen U., Venge P., Lofdahl C. G. Neutrophil-associated activation markers in healthy smokers relates to a fall in DL(CO) and to emphysematous changes on high resolution CT. Respir. Med. 2001; 95: 363–373
  • Feinleib M., Rosenberg H. M., Collins J. G., Delozier J. E., Pokras R., Chevarley F. M. Trends in COPD morbidity and mortality in the United States. Am. Rev. Respir. Dis. 1989; 140: S9–S18
  • Finkelstein R., Fraser R. S., Ghezzo H., Cosio M. G. Alveolar inflammation and its relation to emphysema in smokers. Am. J. Respir. Crit. Care Med. 1995; 152: 1666–1672
  • Groneberg D. A., Chung K. F. Models of chronic obstructive pulmonary disease. Respir. Res. 2004; 5: 18
  • Guerassimov A., Hoshino Y., Takubo Y., Turcotte A., Yamamoto M., Ghezzo H., Triantafillopoulos A., Whittaker K., Hoidal J. R., Cosio M. G. The development of emphysema in cigarette smoke-exposed mice is strain dependent. Am. J. Respir. Crit. Care Med. 2004; 170: 974–980
  • Henry C. J., Kouri R. E. Chronic inhalation studies in mice. II. Effects of long-term exposure to 2R1 cigarette smoke on (C57BL/Cum × C3H/AnfCum)F1 mice. JNCI 1986; 77: 203–212
  • Higuchi M. A., Sagartz J., Shreve W. K., Ayres P. H. Comparative subchronic inhalation study of smoke from the 1R4F and 2R4F reference cigarettes. Inhal. Toxicol. 2004; 16: 1–20
  • Hodge-Bell K., Lee K. M., Hayden B. K., MacIssac B. D., Wisse L. A., Harbo S. J., McKinney W. J. (2006) Constituent and biological characterization of mainstream cigarette smoke generated from a direct pump exposure system. Frontiers in aerosol dosimetry research: Proceedings of a Conference Held in Irvine, California, October, 24–252005, R. Phalen, M. Oldham, S. Akhavan, M. Hoover, K. Asotra. Irvine, CA
  • Huber G. L., Davies P., Zwilling G. R., Pochay V. E., Hinds W. C., Nicholas H. A., Mahajan V. K., Hayashi M., First M. W. A morphologic and physiologic bioassay for quantifying alterations in the lung following experimental chronic inhalation of tobacco smoke. Bull. Eur. Physiopathol. Respir. 1981; 17: 269–327
  • Hunninghake G. W., Crystal R. G. Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers 117. Am. Rev. Respir. Dis. 1983; 128: 833–838
  • ISO. International Standard ISO 3402: Tobacco and tobacco products—Atmosphere for conditioning and testing, 3rd ed. International Organization for Standardization, Geneva 1991
  • Kawasaki S., Takizawa H., Yoneyama H., Nakayama T., Fujisawa R., Izumizaki M., Imai T., Yoshie O., Homma I., Yamamoto K., Matsushima K. Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice. J. Immunol. 2001; 166: 2055–2062
  • Lewis D. J. Factors affecting the distribution of tobacco smoke-induced lesions in the rodent larynx 3736. Toxicol. Lett. 1981; 9: 189–194
  • Ludwig P. W., Schwartz B. A., Hoidal J. R., Niewoehner D. E. Cigarette smoking causes accumulation of polymorphonuclear leukocytes in alveolar septum. Am. Rev. Respir. Dis. 1985; 131: 828–830
  • Majo J., Ghezzo H., Cosio M. G. Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur. Respir. J. 2001; 17: 946–953
  • March T. H., Barr E. B., Finch G. L., Hahn F. F., Hobbs C. H., Menache M. G., Nikula K. J. Cigarette smoke exposure produces more evidence of emphysema in B6C3F1 mice than in F344 rats. Toxicol. Sci. 1999; 51: 289–299
  • March T. H., Barr E. B., Finch G. L., Nikula K. J., Seagrave J. C. Effects of concurrent ozone exposure on the pathogenesis of cigarette smoke-induced emphysema in B6C3F1 mice. Inhal. Toxicol. 2002; 14: 1187–1213
  • March T. H., Wilder J. A., Esparza D. C., Cossey P. Y., Blair L. F., Herrera L. K., McDonald J. D., Campen M. J., Mauderly J. L., Segrave J. C. Modulators of cigarette smoke-induced pulmonary emphysema in A/J mice. Toxicol. Sci. 2006; 92: 545–559
  • Maus U., Herold S., Muth H., Maus R., Ermert L., Ermert M., Weissmann N., Rosseau S., Seeger W., Grimminger F., Lohmeyer J. Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14. Am. J. Physiol. Lung Cell Mol. Physiol. 2001; 280: L58–L68
  • McCusker K., Hoidal J. Selective increase of antioxidant enzyme activity in the alveolar macrophages from cigarette smokers and smoke-exposed hamsters. Am. Rev. Respir. Dis. 1990; 141: 678–682
  • Miller L. M., Foster W. M., Dambach D. M., Doebler D., McKinnon M., Killar L., Longphre M. A murine model of cigarette smoke-induced pulmonary inflammation using intranasally administered smoke-conditioned medium. Exp. Lung Res. 2002; 28: 435–455
  • Montuschi P., Kharitonov S. A., Ciabattoni G., Corradi M., van Rensen L., Geddes D. M., Hodson M. E., Barnes P. J. Exhaled 8-isoprostane as a new non-invasive biomarker of oxidative stress in cystic fibrosis. Thorax 2000; 55: 205–209
  • National Research Council. Guide of the care and use of laboratory animals, et al. National Academy Press, Washington, DC 1996
  • Obot C., Lee K., Fuciarelli A., Renne R., McKinney W. Characterization of mainstream cigarette smoke-induced biomarker responses in ICR and C57Bl/6 mice. Inhal. Toxicol. 2004; 16: 701–19
  • Organization for Economic Cooperation and Development. OECD guideline 413, subchronic toxicity: 90-Days study. OECD Publication Office, Paris 1981
  • Oudijk E. J., Lammers J. W., Koenderman L. Systemic inflammation in chronic obstructive pulmonary disease. Eur. Respir. J. Suppl. 2003; 46: 5s–13s
  • Parameswaran H., Majumdar A., Ito S., Alencar A. M., Suki B. Quantitative characterization of airspace enlargement in emphysema. J. Appl. Physiol. 2006; 100: 186–193
  • Pauwels R. A., Buist A. S., Calverley P. M., Jenkins C. R., Hurd S. S. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am. J. Respir. Crit. Care Med. 2001; 163: 1256–1276
  • Renne R. A., Sagartz J. W., Burger G. T. Interspecies variations in the histology of toxicologically important areas in the larynges of CRL:CD rats and Syrian golden hamsters. Toxicol. Pathol. 1993; 21: 542–546
  • Rosseau S., Hammerl P., Maus U., Walmrath H. D., Schutte H., Grimminger F., Seeger W., Lohmeyer J. Phenotypic characterization of alveolar monocyte recruitment in acute respiratory distress syndrome. Am. J. Physiol. Lung Cell Mol. Physiol. 2000; 279: L25–L35
  • Saetta M., Turato G., Maestrelli P., Mapp C. E.m, Fabbri L. M. Cellular and structural bases of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2001; 163: 1304–1309
  • Snider G. L. Distinguishing among asthma, chronic bronchitis, and emphysema. Chest 1985; 87: 35S–39S
  • Snider G. L. Experimental studies on emphysema and chronic bronchial injury. Eur. J. Respir. Dis. 1986; 69: 17–35, (suppl. 146)
  • Takubo Y., Guerassimov A., Ghezzo H., Triantafillopoulos A., Bates J. H., Hoidal J. R., Cosio M. G. Alpha1-antitrypsin determines the pattern of emphysema and function in tobacco smoke-exposed mice: Parallels with human disease. Am. J. Respir. Crit. Care Med. 2002; 6: 1596–1603
  • Tanino M., Betsuyaku T., Takeyabu K., Tanino Y., Yamaguchi E., Miyamoto K., Nishimura M. Increased levels of interleukin-8 in BAL fluid from smokers susceptible to pulmonary emphysema. Thorax 2002; 57: 405–411
  • Tomita K., Caramori G., Lim S., Ito K., Hanazawa T., Oates T., Chiselita I., Jazrawi E., Chung K. F., Barnes P. J., Adcock I. M. Increased p21CIP1/WAF1 and B cell lymphoma leukemia-xL expression and reduced apoptosis in alveolar macrophages from smokers. Am. J. Respir. Crit. Care Med. 2002; 66: 724–731
  • Vanscheeuwijck P. M., Teredesai A., Terpstra P. M., Verbeeck J., Kuhl P., Gerstenberg B., Gebel S., Carmines E. L. Evaluation of the potential effects of ingredients added to cigarettes. Part 4: Subchronic inhalation toxicity. Food Chem. Toxicol. 2002; 40: 113–131
  • Weibel E. R. Morphometry of the human lung: The state of the art after two decades. Bull. Eur. Physiopathol. Respir. 1979; 15: 999–1013
  • Willemse B. W., Ten Hacken N. T., Rutgers B., Postma D. S.m, Timens W. Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers. Respir. Res. 2005; 6: 38
  • Young J. T. Histopathologic examination of the rat nasal cavity. Fundam. Appl. Toxicol. 1981; 1: 309–312

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.