Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 20, 2008 - Issue 7
178
Views
21
CrossRef citations to date
0
Altmetric
Research Article

Carbon Monoxide Levels Experienced by Heavy Smokers Impair Aerobic Capacity and Cardiac Contractility and Induce Pathological Hypertrophy

, , , , , , , , , , , , , , , , & show all
Pages 635-646 | Received 04 Dec 2007, Accepted 26 Dec 2007, Published online: 06 Oct 2008

REFERENCES

  • Aparici M., Fernandez Gonzalez A. L., Alegria E. [Aerobic capacity. Differences between smokers and non-smokers. Effects of withdrawal]. Rev. Clin. Esp. 1993; 193: 424–427
  • Astrup P., Kjeldsen K., Wanstrup J. Effects of carbon monoxide exposure on the arterial walls. Ann. NY Acad. Sci. 1970; 174: 294–300
  • Butler R., Morris A. D., Struthers A. D. Cigarette smoking in men and vascular responsiveness. Br. J. Clin. Pharmacol. 2001; 52: 145–149
  • Celermajer D. S., Adams M. R., Clarkson P., Robinson J., McCredie R., Donald A., Deanfield J. E. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N. Engl. J. Med. 1996; 334: 150–154
  • Currie S., Smith G. L. Enhanced phosphorylation of phospholamban and downregulation of sarco/endoplasmic reticulum Ca2 + ATPase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure. Cardiovasc. Res. 1999; 41: 135–146
  • Davis R. J. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 1993; 268: 14553–14556
  • Flesch M., Kilter H., Cremers B., Lenz O., Sudkamp M., Kuhn-Regnier F., Bohm M. Acute effects of nitric oxide and cyclic GMP on human myocardial contractility. J. Pharmacol. Exp. Ther. 1997; 281: 1340–1349
  • Graser T., Vedernikov Y. P., Li D. S. Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein. Biomed. Biochim. Acta 1990; 49: 293–296
  • Hajjar R. J., Schwinger R. H., Schmidt U., Kim C. S., Lebeche D., Doye A. A., Gwathmey J. K. Myofilament calcium regulation in human myocardium. Circulation 2000; 101: 1679–1685
  • Haram P. M., Adams V., Kemi O. J., Brubakk A. O., Hambrecht R., Ellingsen O., Wisloff U. Time-course of endothelial adaptation following acute and regular exercise. Eur. J. Cardiovasc. Prev. Rehab. 2006; 13: 585–591
  • Hirsch G. L., Sue D. Y., Wasserman K., Robinson T. E., Hansen J. E. Immediate effects of cigarette smoking on cardiorespiratory responses to exercise. J. Appl. Physiol. 1985; 58: 1975–1981
  • Houser S. R., Margulies K. B. Is depressed myocyte contractility centrally involved in heart failure?. Circ. Res. 2003; 92: 350–358
  • Huang B., Wang S., Qin D., Boutjdir M., El-Sherif N. Diminished basal phosphorylation level of phospholamban in the postinfarction remodeled rat ventricle: role of beta-adrenergic pathway, G(i) protein, phosphodiesterase, and phosphatases. Circ. Res. 1999; 85: 848–855
  • Hutchison S. J., Sudhir K., Chou T. M., Sievers R. E., Zhu B. Q., Sun Y. P., Deedwania P. C., Glantz S. A., Parmley W. W., Chatterjee K. Testosterone worsens endothelial dysfunction associated with hypercholesterolemia and environmental tobacco smoke exposure in male rabbit aorta. J. Am. Coll. Cardiol. 1997; 29: 800–807
  • Kjeldsen K., Thomsen H. K., Astrup P. Effects of carbon monoxide on myocardium. Ultrastructural changes in rabbits after moderate, chronic exposure. Circ. Res. 1974; 34: 339–348
  • Kumar P. R., Kumar N. V. Effect of cigarette smoking on muscle strength of flexibility of athletes. Indian J. Exp. Biol. 1998; 36: 1144–1146
  • Larsen K. O., Sjaastad I., Svindland A., Krobert K. A., Skjonsberg O. H., Christensen G. Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice. Am. J. Physiol. 2006; 291: H507–516
  • Levy D., Garrison R. J., Savage D. D., Kannel W. B., Castelli W. P. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N. Engl. J. Med. 1990; 322: 1561–1566
  • Loennechen J. P., Beisvag V., Arbo I., Waldum H. L., Sandvik A. K., Knardahl S., Ellingsen O. Chronic carbon monoxide exposure in vivo induces myocardial endothelin-1 expression and hypertrophy in rat. Pharmacol. Toxicol. 1999; 85: 192–197
  • Loennechen J. P., Nilsen O. G., Arbo I., Aadahl P., Nilsen T., Waldum H. L., Sandvik A. K., Ellingsen O. Chronic exposure to carbon monoxide and nicotine: Endothelin ET(A) receptor antagonism attenuates carbon monoxide-induced myocardial hypertrophy in rat. Toxicology Appl. Pharmacol. 2002; 178: 8–14
  • Mery P. F., Pavoine C., Belhassen L., Pecker F., Fischmeister R. Nitric oxide regulates cardiac Ca2 + current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation. J. Biol. Chem. 1993; 268: 26286–26295
  • Mirza A., Eder V., Rochefort G. Y., Hyvelin J. M., Machet M. C., Fauchier L., Bonnet P. CO inhalation at dose corresponding to tobacco smoke worsens cardiac remodeling after experimental myocardial infarction in rats. Toxicol. Sci. 2005; 85: 976–982
  • Molkentin J. D., Lu J. R., Antos C. L., Markham B., Richardson J., Robbins J., Grant S. R., Olson E. N. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 1998; 93: 215–228
  • Otterbein L. E., Mantell L. L., Choi A. M. Carbon monoxide provides protection against hyperoxic lung injury. Am. J. Physiol. 1999; 276: L688–694
  • Pei J. M., Kravtsov G. M., Wu S., Das R., Fung M. L., Wong T. M. Calcium homeostasis in rat cardiomyocytes during chronic hypoxia: A time course study. Am. J. Physiol. Cell Physiol. 2003; 285: C1420–1428
  • Pei J. M., Yu X. C., Fung M. L., Zhou J. J., Cheung C. S., Wong N. S., Leung M. P., Wong T. M. Impaired G(s)alpha and adenylyl cyclase cause beta-adrenoceptor desensitization in chronically hypoxic rat hearts. Am. J. Physiol. Cell Physiol. 2000; 279: C1455–1463
  • Penn A., Currie J., Snyder C. Inhalation of carbon monoxide does not accelerate arteriosclerosis in cockerels. Eur. J. Pharmacol. 1992; 228: 155–164
  • Penney D. G., Howley J. W. Is there a connection between carbon monoxide exposure and hypertension?. Environ. Health Perspect. 1991; 95: 191–198
  • Peterson J. E., Stewart R. D. Absorption and elimination of carbon monoxide by inactive young men. Arch. Environ. Health 1970; 21: 165–171
  • Quinn F. R., Currie S., Duncan A. M., Miller S., Sayeed R., Cobbe S. M., Smith G. L. Myocardial infarction causes increased expression but decreased activity of the myocardial Na+-Ca2 + exchanger in the rabbit. J. Physiol. 2003; 553: 229–242
  • Rehder K. A. I., Roth G. M. Effect of smoking on the fasting blood sugar and pressor amines. Circulation 1959; 20: 224–228
  • Ronnemaa E. M., Ronnemaa T., Utriainen T., Raitakari M., Laine H., Takala T., Pitkanen O. P., Kirvela O., Knuuti J., Nuutila P. Decreased blood flow but unaltered insulin sensitivity of glucose uptake in skeletal muscle of chronic smokers. Metab. Clin. Exp. 1999; 48: 239–244
  • Sorhaug S., Steinshamn S., Nilsen O. G., Waldum H. L. Chronic inhalation of carbon monoxide: Effects on the respiratory and cardiovascular system at doses corresponding to tobacco smoking. Toxicology 2006; 228: 280–290
  • Stupfel M., Bouley G. Physiological and biochemical effects on rats and mice exposed to small concentrations of carbon monoxide for long periods. Ann. NY Acad. Sci. 1970; 174: 342–368
  • Turner D. M., Lee P. N., Roe F. J., Gough K. J. Atherogenesis in the White Carneau pigeon. Further studies of the role of carbon monoxide and dietary cholesterol. Atherosclerosis 1979; 34: 407–417
  • Ventura-Clapier R., Garnier A., Veksler V. Energy metabolism in heart failure. J. Physiol. 2004; 555: 1–13
  • Wilkins B. J., Dai Y. S., Bueno O. F., Parsons S. A., Xu J., Plank D. M., Jones F., Kimball T. R., Molkentin J. D. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ. Res. 2004; 94: 110–118
  • Wisloff U., Helgerud J., Kemi O. J., Ellingsen O. Intensity-controlled treadmill running in rats: VO(2 max) and cardiac hypertrophy. Am. J. Physiol. 2001; 280: H1301–1310
  • Wisloff U., Loennechen J. P., Currie S., Smith G. L., Ellingsen O. Aerobic exercise reduces cardiomyocyte hypertrophy and increases contractility, Ca2 + sensitivity and SERCA-2 in rat after myocardial infarction. Cardiovasc. Res. 2002; 54: 162–174
  • Yandle T. G., Richards A. M., Gilbert A., Fisher S., Holmes S., Espiner E. A. Assay of brain natriuretic peptide (BNP) in human plasma: Evidence for high molecular weight BNP as a major plasma component in heart failure. J. Clin. Endocrinol. Metab. 1993; 76: 832–838
  • Zeiher A. M., Schachinger V., Minners J. Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function. Circulation 1995; 92: 1094–1100

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.