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Inhalation Toxicology
International Forum for Respiratory Research
Volume 32, 2020 - Issue 8
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Letter to the Editor

Letter concerning: Clewell (2019) incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene

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Page 327 | Received 02 Apr 2020, Accepted 30 Jul 2020, Published online: 14 Aug 2020

References

  • Boxenmaum  1982. Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics. J Pharmacokinet Biopharm. 10:201–227.
  • Clewell HJ, Campbell JL, Van Landingham C, Franzen A, Yoon M, Dodd DE, Andersen ME, Gentry PR. 2019. Incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene. Inhal Toxicol. 31:468–483.
  • Filser JG, Klein D. 2018. A physiologically based toxicokinetic model for inhaled ethylene and ethylene oxide in mouse, rat and human. Toxicol Lett. 286:54–79.
  • Hattis D. 1987. A pharmacokinetic/mechanism-based analysis of the carcinogenic risk of ethylene oxide. Cambridge (MA): Center for Technology, Policy and Industrial Development, MIT. National Technical Information Service. CTPID 87-1, NTIS/PB88-188784.
  • Spearman John R. 2005. Body size, energy metabolism and lifespan. J Exp Biol. 208:1717–1730.

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