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Inhalation Toxicology
International Forum for Respiratory Research
Volume 9, 1997 - Issue 1
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Research Article

BIOCHEMICAL ALTERATIONS IN RAT LUNG LAVAGE FLUID FOLLOWING ACUTE SULFUR MUSTARD INHALATION: II. INCREASES IN PROTEOLYTIC ACTIVITY

Pages 53-61 | Published online: 01 Oct 2008

References

  • All, S. T., and Ray, P. 1996. Identification and partial characterization of mustard stimulated pro-tease in normal human epidermal keratinocytes. Medical Defense Biosci. Rev., USAMRICD, Baltimore, MD, May 12–16, p. 122.
  • Anderson, D. R., Byers, S. L., Clark, C. R., and Schlehr, J. A. 1995. Changes in rat lung lavage fluid following acute sulfur mustard inhalation. FASEBJ. 9(4):A4151.
  • Anderson, D. R., Yourick, J. J., Moeller, R. B., Petrali, J. P., Young, G. D., and Byers, S. L. 1996. Pathologic changes in rat lungs following acute sulfur mustard inhalation. InhaL Toxicol. 8:285–297.
  • Bongiovanni, R., Millard, C. B., Schulz, S. M., and Romano, J. M. 1993. Estimation of neu-trophil infiltration into hairless guinea pig skin treated with 2,2'-dich lorodiethyl sulfide. Proc. 1993 Medical Defense Biosci. Rev., USAMRICD, Aberdeen Proving Ground, MD, May 10–13. Vol. 1, pp. 389–395. ADA2 75667.
  • Calvet, J. H., Jarreau, P. H., Levame, M., D'Ortho, M. P., Lorino, H., Harf, A., and Macquin-Mavier, I. 1994. Acute and chronic respiratory effects of sulfur mustard intoxication in guinea pig.]. AppL PhysioL 76(2):681–688.
  • Casillas, R. P., Smith, K. J., Lee, R. B., Castrejon, L. R., and Stemler, F. W. 1 996. Effect of top-ically applied drugs against HD-induced cutaneous injury in the mouse ear edema model. 1996 Medical Defense Biosci. Rev., USAMRICD, Baltimore, MD, May 12–16, p.135.
  • Chan, I. J., and Tharp, M. D. 1994. Rat mast cell protease I alters cell metabolism.]. Invest. DermatoL 103:84–87.
  • Cirino, G., Cicala, C., Bucci, M. R., Sorrentino, L., Maraganore, J. M., and Stone, S. R. 1996. Thrombin functions as an inflammatory mediator through activation of its receptor. J. Exp. Med. 183:821–827.
  • Cowan, F. M., and Broomfield, C. A. 1993. Putative roles of inflammation in the dermatopathol-ogy of sulfur mustard. Cell Biol. Toxicol. 9(3):201–213.
  • Cowan, F. M., Broomfield, C. A., and Smith, W. J. 1 991. Effect of sulfur mustard on protease activity in human peripheral blood lymphocytes. Cell Biol. Toxicol. 7(3):239–248.
  • Cowan, F. M., Broomfield, C. A., and Smith, W. J. 1992. Inhibition of sulfur mustard-increased protease activity by niacinamide, N-acetyl-L-cysteine or dexamethasone. Cell Biol. Toxicol. 8(2):9–133.
  • Cowan, F. M., Yourick, J. J., Hurst, C. G., Broomfield, C. A., and Smith, W. J. 1993. Sulfur mustard-increased proteolysis following in vitro and in vivo exposures. Cell Biol. Toxicol. 9(3):253–261.
  • Cowan, F. M., Bongiovanni, R., Broomfield, C. A., Schulz, S. M., and Smith, W. J. 1994a. Phenidone and hydroxyurea reduce sulfur mustard-increased proteolysis in hairless guinea pig skin./ Toxicol. Cutaneous Ocular Toxicol. 14(4):265–272.
  • Cowan, F. M., Bongiovanni, R., Broomfield, C. A., Yourick, J. J., and Smith, W. J. 1 994b. Sulfur mustard increases elastase-like activities in homogenates of hairless guinea pig skin. J. Toxicol. Cutaneous Ocular Toxicol. 13(3):221–229.
  • Cowan, F. M., Broomfield, C. A., and Smith, W. J. 1 996. Enhanced proteolytic activity and Fc receptor expression in human epithelial cells following exposure to sulfur mustard. 1996 Medical Defense Biosci. Rev., USAMRICD, Baltimore, MD, May 12–1 6, p. 138.
  • Friberger, P.1982. Chromogenic peptide substrates. Scand. J. Clin. Lab. Invest. 42\(suppl. 162):1–98. Giuliani, I., Boivieux-Ulrich, E., Houcine, 0., Guennou, C., and Marano, F. 1 994. Toxic effects of mechlorethamine on mammalian respiratory mucociliary epithelium in primary culture.
  • Cell Biol. Toxicol. 10:231–246.
  • Gross, C. L., Innace, J. K., Hovatter, R. C., Meir, H. L., and Smith, W. J. 1993. Biochemical manipulation of intracellular glutathione levels influences cytotoxicity to isolated human lym-phocytes by sulfur mustard. Cell Biol. Toxicol. 9(3):259–268.
  • Higuchi, K., Kajiki, A., Nakamura, M., Harada, S., Pula, P. J., Scott, A. L., and Dannenburg, A. M. 1988. Protease released in organ culture by acute inflammatory lesions produced in vivo in rabbit skin by sulfur mustard: Hydrolysis of synthetic peptide substrates for trypsin-like and chymotrypsin-like enzymes. Inflammation 12:311–334.
  • Hunyadi, J., Simon, M., Jr., and Dobozy, A. 1992. Immune-associated surface markers of human keratinocytes. Immunol. Lett. 31: 209–216.
  • Katayama, H., Hase, T., and Yaoita, H. 1994. Detachment of cultured normal human ker-atinocytes by contact with TNF-stimulated neutrophils in the presence of platelet-activating factor./ Invest. Dermatol. 103:187–190.
  • Lindsay, C. D., Hambrook, J. L., Smith, C. N., and Rice, P. 1996. Histological assessment of the effects of percutaneous exposure of sulfur mustard in an in vitro human skin system and the therapeutic properties of protease inhibitors. 1996 Medical Defense Biosci. Rev., USAMRICD, Baltimore, MD, May 12–16, p. 148.
  • Meier, H. L., Gross, C. L., and Papirmeister, B. 1987. 2,2'-Dichlorodiethyl sulfide (sulfur mustard) decreases NAD+ in human leukocytes. Toxicol. Lett. 39:109–122.
  • Oikarinen, A., Hoyhtha, M., and Jarvineny, M. 1990. Dexamethasone-induced plasminogen activa-tor inhibitor: Characterization, purification, and preparation of monoclonal antibodies. Dermatol. Res. 282:153–158.
  • Papirmeister, B., Gross, C. L., Meier, H. L., Petrali, J. P., and Johnson, J. B. 1985. Molecular basis for mustard-induced vesication. Fundam.AppL Toxicol. 5:S134—S149.
  • Papirmeister, B., Feister, A. J., Robinson, S. I., and Ford, R. D. 1991. Medical defense against mustard gas: Toxic mechanisms and pharmacological implications, pp. 1–359. Boston: CRC Press.
  • Pechura, C. M., and Rall, D. P., eds. 1993. Veterans at risk, the health effects of mustard gas and lewisite. Washington, DC: National Academy Press.
  • Smith, W. J., Cowan, F. M., and Broomfield, C. A. 1991. Increased proteolytic activity in human epithelial cells following exposure to sulfur mustard. FASEB J. 5:A828.

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