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Original Article

Effects of Local Application of Growth and Differentiation Factor-5 (GDF-5) in a Full-thickness Cartilage Defect Model

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Pages 35-43 | Published online: 07 Aug 2009

References

  • Altman, R.D., Kates, J., Chun, L.E., Dean, D.D. and Eyre, D. (1992) "Preliminary observations of chondral abrasion in a canine model", Ann. Rheum. Dis. 51, 1056-1062.
  • Bailey, A.J. and Mansell, J.P. (1997) "Do subchondral bone changes exacerbate or precede articular cartilage destruction in osteoarthritis of the elderly?", Gerontology 43(5), 296-304.
  • Bert, J.M. and Maschka, K. (1989) "The arthroscopic treatment of unicompartmental gonarthrosis: a five-year follow-up study of abrasion arthroplasty plus arthroscopic debridement and arthroscopic debridement alone", Arthroscopy 5(1), 25-32.
  • Burr, D.B. and Schaffler, M.B. (1997) "The involvement of subchondral mineralized tissues in osteoarthrosis: quantitative microscopic evidence", Microsc. Res. Tech. 37(4), 343-357.
  • Buxton, P., Edwards, C., Archer, C.W. and Francis-West, P. (2001) "Growth/differentiation factor-5 (GDF-5) and skeletal development", J. Bone Joint Surg. Am. 83-A (Suppl. 1)(Pt 1), S23-S30.
  • Chang, S.C., Hoang, B., Thomas, J.T., Vukicevic, S., Luyten, F.P., Ryba, N.J., Kozak, C.A., Reddi, A.H. and Moos, M. (1994) "Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development", J. Biol. Chem. 269(45), 28227-28234.
  • Conn, H.J. and Lillie, R.D. (1977) Biological Stains, 9th Edn. (Waverly Press, Baltimore), p. 387.
  • Ehemann, V., Hashemi, B., Lange, A. and Otto, H.F. (1999) "Flow cytometric DNA analysis and chromosomal aberrations in malignant glioblastomas", Cancer Lett. 138, 101-106.
  • Ehemann, V., Sykora, J., Vera-Delgado, J., Lange, A. and Otto, H.F. (2003) "Flow cytometric detection of spontaneous apoptosis in human breast cancer using TUNEL-technique", Cancer Lett. 194, 125-131.
  • Erggelet, C., Mandelbaum, B. and Lahm, A. (2000) "Der Knorpelscha-den als therapeutische Aufgabe-Klinische Grundlagen", Dtsch. Z. Sportmed. 51(2), 48-54.
  • Erlacher, L., Ng, C.K., Ullrich, R., Krieger, S. and Luyten, F.P. (1998) "Presence of cartilage-derived morphogenetic proteins in articular cartilage and enhancement of matrix replacement in vitro", Arthritis Rheum. 41(2), 263-273.
  • Gavrieli, Y., Sherman, Y. and Ben-Sasson, S.A. (1992) "Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation", J. Cell. Biol. 119(3), 493-501.
  • Hotten, G.C., Matsumoto, T., Kimura, M., Bechtold, R.F., Kron, R., Ohara, T., Tanaka, H., Satoh, Y., Okazaki, M., Shirai, T., Pan, H., Kawai, S., Pohl, J.S. and Kudo, A. (1996) "Recombinant human growth/differentiation factor 5 stimulates mesenchyme aggregation and chondrogenesis responsible for the skeletal development of limbs", Growth Factors 13(1-2), 65-74.
  • Hunziker, E.B. and Kapfinger, E. (1998) "Removal of proteoglycans from the surface of defects in articular cartilage transiently enhances coverage by repair cells", J. Bone Joint Surg. Br. 80(1), 144-150.
  • Hunzinger, E.B. (2001) "Growth factor induced healing of partial thickness defects in adult articular cartilage", Osteoarthritis Cartilage 9, 22-32.
  • King, J.A., Storm, E.E., Marker, P.C., Dileone, R.J. and Kingsley, D.M. (1996) "The role of BMPs and GDFs in development of region-specific skeletal structures", Ann. N. Y. Acad. Sci. 8(785), 70-79.
  • Kirker-Head, C.A., Gerhart, T.N., Schelling, S.H., Hennig, G.E., Wang, E. and Holtrop, M.E. (1995) "Long-term healing of bone using recombinant human bone morphogenetic protein 2", Clin. Orthop. 318, 222-230.
  • Luyten, F.P. (1995) "Cartilage-derived morphogenetic proteins. Key regulators in chondrocyte differentiation?", Acta Orthop. Scand. Suppl. 266, 51-54.
  • Meachim, G. and Roberts, C. (1971) "Repair of the joint surface from subarticular tissue in the rabbit knee", J. Anat. 109, 317-327.
  • Mitchell, N. and Shepard, N. (1976) "The resurfacing of adult rabbit articular cartilage by multiple perforations through the subchondral bone", J. Bone Joint Surg. Am. 58(2), 230-233.
  • Mundy, G.R. (1995) "Local control of bone formation by osteoblasts", Clin. Orthop. 313, 19-26.
  • Nishitoh, H., Ichijo, H., Kimura, M., Matsumoto, T., Makishima, F., Yamaguchi, A., Yamashita, H., Enomoto, S. and Miyazono, K. (1996) "Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5", J. Biol. Chem. 271(35), 21345-21352.
  • O'Driscoll, S.W. (1998) "The healing and regeneration of articular cartilage", J. Bone Joint Surg. Am. 80(12), 1795-1812.
  • Otto, F.J. (1998) "High resolution analysis of unclear DNA employing the fluorochrome DAPI", Meth. Cell Biol. 41, 211-217.
  • Pineda, S., Pollack, A., Stevenson, S., Goldberg, V. and Caplan, A. (1992) "A semiquantitative scale for histologic grading of articular cartilage repair", Acta Anat. (Basel) 143(4), 335-340.
  • Rosenberg, L. and Hunzinger, E.B. (1994) "Cartilage repair in osteoarthritis. The role of the dermatan sulfate proteoglycanes", In: Kuettner, K.E. and Goldberg, V., eds, Osteoarthritis Disorder (The American Academy of Orthopedic Surgeons, Park Ridge, IL), pp. 341-356.
  • Sellers, R.S., Peluso, D. and Morris, E.A. (1997) "The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage", J. Bone Joint Surg. Am. 79(10), 1452-1463.
  • Sergi, C., Kahl, P. and Otto, H.F. (2000) "Contribution of apoptosis and apoptosis-related proteins to the malformation of the primitive intrahepatic biliary system in Meckel syndrome", Am. J. Pathol. 156(5), 1589-1598.
  • Shapiro, F., Koide, S. and Glimcher, M.J. (1993) "Cell origin and differentiation in the repair of full-thickness defects of articular cartilage", J. Bone Joint Surg. 75(A), 532-553.
  • Steadman, J.R., Rodkey, W.G., Briggs, K.K. and Rodrigo, J.J. (1999) "The microfracture technic in the management of complete cartilage defects in the knee joint", Orthopade 28(1), 26-32.
  • Uludag, H., Gao, T., Porter, T.J., Friess, W. and Wozney, J.M. (2001) "Delivery systems for BMPs: factors contributing to protein retention at an application site", J. Bone Joint Surg. Am. 83-A Suppl. 1(Pt 2), S128-S135.
  • Vachon, A., Bramlage, L.R., Gabel, A.A. and Weisbrode, S. (1986) "Evaluation of the repair process of cartilage defects of the equine third carpal bone with and without subchondral bone perforation", Am. J. Vet. Res. 47(12), 2637–2645.

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