Ligands to FGF receptor 2-IIIb induce proliferation, motility, protection from cell death and cytoskeletal rearrangements in epithelial ovarian cancer cell lines

References

• Auersperg N, Wong WST, Choi KC, Kang SK, Leung PCK. Ovarian surface epithelium: Biology, endocrinology and pathology. Endocr Rev 2001; 22: 255–288
   PubMed Web of Science ®Google Scholar
• Basilico C, Moscatelli D. The FGF family of growth factors and oncogenes. Adv Cancer Res 1992; 59: 115–165
   PubMed Web of Science ®Google Scholar
• Beiman M, Shilo BZ, Volk T. Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. Genes Dev 1996; 10: 2993–3002
   PubMed Web of Science ®Google Scholar
• Buckley S, Barsky L, Driscoll B, Weinberg K, Anderson KD, Warburton D. Apoptosis and DNA damage in type 2 alveolar epithelial cells cultured from hyperoxic rats. Am J Physiol 1998; 274: L714–L720
   Google Scholar
• Crickard K, Gross JL, Crickard U, Yoonessi M, Lele S, Herblin WF, Eidsvoog K. Basic fibroblast growth factor and receptor expression in human ovarian cancer. Gynecol Oncol 1994; 55: 277–284
   PubMed Web of Science ®Google Scholar
• Cohen MM. Neoplasms associated with alterations in fibroblastgrowth factor receptors. Am J Med Genet 2003; 119A: 97–100
   PubMed Web of Science ®Google Scholar
• Davies BR, Steele IA, Edmondson RJ, Zwolinski SA, Saretzki G, Von Zglinicki T, O'Hare MJ. Immortalisation of human ovarian surface epithelium with telomerase and temperature-sensitive SV40 large T antigen. Exp Cell Res 2003; 288: 390–402
   PubMed Web of Science ®Google Scholar
• Di Blasio AM, Cremonesi L, Vigano P, Ferrari M, Gospodarowicz D, Vignali M, Jaffe RB. Basic fibroblast growth factor and its receptor messenger ribonucleic acids are expressed in human ovarian epithelial neoplasms. Am J Obstet Gynecol 1993; 169: 1517–1523
   PubMed Web of Science ®Google Scholar
• Farrell CL, Bready JV, Rex KL, Chen JN, DiPalma CR, Whitcomb KL, Yin S, Hill DC, Wiemann B, Starnes CO, et al. Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality. Cancer Res 1998; 58: 933–939
   PubMed Web of Science ®Google Scholar
• Finch PW, Rubin JS, Miki T, Ron D, Aaronson SA. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science 1989; 245: 752–755
   PubMed Web of Science ®Google Scholar
• Galzie Z, Kinsella AR, Smith JA. Fibroblast growth factors and their receptors. Biochem Cell Biol 1997; 75: 669–685
   PubMed Web of Science ®Google Scholar
• Gisselbrecht S, Skeath JB, Doe CQ, Michelson AM. Heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo. Genes Dev 1996; 10: 3003–3017
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57–70
   PubMed Web of Science ®Google Scholar
• Jouanneau J, Gavrilovic J, Caruelle D, Jaye M, Moens G, Caruelle JP, Thiery JP. Secreted or nonsecreted forms of acidic fibroblast growth factor produced by transfected epithelial cells influence cell morphology, motility, and invasive potential. Proc Natl Acad Sci USA 1991; 88: 2893–2897
   PubMed Web of Science ®Google Scholar
• Khan WB, Shui C, Ning S, Knox SJ. Enhancement of murine intestinal stem cell survival after irradiation by keratinocyte growth factor. Radiat Res 1997; 148: 248–253
   PubMed Web of Science ®Google Scholar
• Kruk PA, Maines-Bandiera SL, Auersperg N. A simplified method to culture human ovarian surface epithelium. Lab Investig 1990; 63: 132–136
   PubMed Web of Science ®Google Scholar
• Kruk PA, Uitto VJ, Firth JD, Dedhar S, Auersperg N. Reciprocal interactions between human ovarian surface epithelial cells and adjacent extracellular matrix. Exp Cell Res 1994; 215: 97–108
   PubMed Web of Science ®Google Scholar
• La Vallee TM, Prudovsky IA, McMahon GA, Hu X, Maciag T. Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration. J Cell Biol 1998; 141: 1647–1658
   PubMed Web of Science ®Google Scholar
• Li S, Muneoka K. Cell migration and chick limb development: Chemotactic action of FGF-4 and the AER. Dev Biol 1999; 211: 335–347
   PubMedGoogle Scholar
• Lu W, Luo Y, Kan M, McKeehan WL. Fibroblast growth factor-10. A second candidate stromal to epithelial cell andromedin in prostate. J Biol Chem 1999; 274: 12827–12834, [published erratum appears in J Biol Chem 1999 Sep 24;274(39):28058]
   PubMed Web of Science ®Google Scholar
• Maher P. p38 Mitogen-activated protein kinase activation is required for fibroblast growth factor-2-stimulated cell proliferation but not differentiation. J Biol Chem 1999; 274: 17491–17498
   PubMed Web of Science ®Google Scholar
• Matzinger P. The JAM test. A simple assay for DNA fragmentation and cell death. J Immunol Methods 1991; 145: 185–192
   PubMed Web of Science ®Google Scholar
• Mehta PB, Robson CN, Neal DE, Leung HY. Keratinocyte growth factor activates p38 MAPK to induce stress fibre formation in human prostate DU145 cells. Oncogene 2001; 20: 5359–5365
   PubMed Web of Science ®Google Scholar
• Miki T, Bottaro DP, Fleming TP, Smith CL, Burgess WH, Chan AM, Aaronson SA. Determination of ligand-binding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci USA 1992; 89: 246–250
   PubMed Web of Science ®Google Scholar
• Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55–63
   PubMed Web of Science ®Google Scholar
• Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M. Receptor specificity of the fibroblast growth factor family. J Biol Chem 1996; 271: 15292–15297
   PubMed Web of Science ®Google Scholar
• Peters K, Werner S, Liao X, Wert S, Whitsett J, Williams L. Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. Embo J 1994; 13: 3296–3301
   PubMed Web of Science ®Google Scholar
• Post M, Souza P, Liu J, Tseu I, Wang J, Kuliszewski M, Tanswell AK. Keratinocyte growth factor and its receptor are involved in regulating early lung branching. Development 1996; 122: 3107–3115
   PubMed Web of Science ®Google Scholar
• Renaud F, Desset S, Oliver L, Gimenez-Gallego G, Van Obberghen E, Courtois Y, Laurent M. The neurotrophic activity of fibroblast growth factor 1 (FGF1) depends on endogenous FGF1 expression and is independent of the mitogen-activated protein kinase cascade pathway. J Biol Chem 1996; 271: 2801–2811
   PubMed Web of Science ®Google Scholar
• Robinson CJ. Growth factors: Therapeutic advances in wound healing. Ann Med 1993; 25: 535–538
   PubMed Web of Science ®Google Scholar
• Rubin JS, Osada H, Finch PW, Taylor WG, Rudikoff S, Aaronson SA. Purification and characterisation of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci USA 1989; 86: 802–806
   PubMed Web of Science ®Google Scholar
• Song S, Guillaume Wientjes M, Gan Y, Au JL-S. Fibroblast growth factors: An epigenetic mechanism of broad specrum resistance to anticancer drugs. Proc Natl Acad Sci USA 2000; 97: 8658–8663
   PubMed Web of Science ®Google Scholar
• Steele IA, Edmondson RJ, Bulmer JN, Bolger BS, Leung HY, Davies BR. Induction of FGF receptor 2-IIIb expression and response to its ligands in epithelial ovarian cancer. Oncogene 2001; 20: 5878–5887
   PubMed Web of Science ®Google Scholar
• Sun X, Meyers EN, Lewandoski M, Martin GR. Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev 1999; 13: 1834–1846
   PubMed Web of Science ®Google Scholar
• Taniguchi F, Harada T, Sakamoto Y, Yamauchi N, Yoshida S, Iwabe T, Terakawa N. Activation of mitogen-activated protein kinase pathway by keratinocyte growth factor or fibroblast growth factor-10 promotes cell proliferation in human endometrial carcinoma cells. J Clin Endocrinol Metab 2003; 88: 773–780
   PubMed Web of Science ®Google Scholar
• Tsuboi R, Sato Y, Rifkin DB. Correlation of cell migration, cell invasion, receptor number, proteinase production, and basic fibroblast growth factor levels in endothelial cells. J Cell Biol 1990; 110: 511–517
   PubMed Web of Science ®Google Scholar
• Valve E, Martikainen P, Seppanen J, Oksjoki S, Hinkka S, Antilla L, Grenman S, Klemi P, Harkonen P. Expression of fibroblast growth factor (FGF)-8 isoforms and FGF receptors in human ovarian tumours. Int J Cancer 2000; 88: 718–725
   PubMed Web of Science ®Google Scholar
• Werner S, Peters KG, Longaker MT, Fuller-Pace F, Banda MJ, Williams LT. Large induction of keratinocyte growth factor expression in the dermis during wound healing. Proc Natl Acad Sci USA 1992; 89: 6896–6900
   PubMed Web of Science ®Google Scholar
• Zang XP, Pento JT. Keratinocyte growth factor-induced motility of breast cancer cells. Clin Exp Metastasis 2001; 18: 573–580
   Web of Science ®Google Scholar
• Zhang Y, Wang H, Toratani S, Denry Sato J, Kan M, McKeehan WL, Okamoto T. Growth inhibition by keratinocyte growth factor receptor of human salivary adenocarcinoma cells through induction of differentiation and apoptosis. Proc Natl Acad Sci USA 2001; 98: 11336–11340
   PubMed Web of Science ®Google Scholar