Cross-talk between IFN-α and TGF-β₁ signaling pathways in preneoplastic rat liver

References

• Alvarez ML, Quiroga AD, Ronco MT, Parody JP, Ochoa JE, Monti JA, et al. Time-dependent onset of Interferon-alpha2b-induced apoptosis in isolated hepatocytes from preneoplastic rat livers. Cytokine 2006; 36: 245–253
   PubMed Web of Science ®Google Scholar
• Attisano L, Wrana JL. Signal transduction by the TGF-beta superfamily. Science 2002; 296: 1646–1647
   PubMed Web of Science ®Google Scholar
• Biggs JR, Kraft AS. The role of the Smad3 protein in phorbol ester-induced promoter expression. J Biol Chem 1999; 274: 36987–36994
   PubMedGoogle Scholar
• de Lujan AM, Cerliani JP, Monti J, Carnovale C, Ronco MT, Pisani G, et al. The in vivo apoptotic effect of interferon alfa-2b on rat preneoplastic liver involves Bax protein. Hepatology 2002; 35: 824–833
   PubMed Web of Science ®Google Scholar
• de Lujan AM, Ronco MT, Ochoa JE, Monti JA, Carnovale CE, Pisani GB, et al. Interferon alpha-induced apoptosis on rat preneoplastic liver is mediated by hepatocytic transforming growth factor beta(1). Hepatology 2004; 40: 394–402
   PubMed Web of Science ®Google Scholar
• De Duve C, Pressman BC, Gianetto R, Wattiaux R, Ppelmans F. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem J 1955; 60: 604–617
   PubMed Web of Science ®Google Scholar
• Ebisawa T, Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamuta T, et al. Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation. J Biol Chem 2001; 276: 12477–12480
   PubMed Web of Science ®Google Scholar
• Foser S, Redwanz I, Ebeling M, Heizmann CW, Certa U. Interferon-alpha and transforming growth factor-beta co-induce growth inhibition of human tumor cells. Cell Mol Life Sci 2006; 63: 2387–2396
   PubMedGoogle Scholar
• Ghosh AK, Varga J. The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis. J Cell Physiol 2007; 213: 663–671
   PubMed Web of Science ®Google Scholar
• Ghosh AK, Yuan W, Mori Y, Chen S, Varga J. Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivators. J Biol Chem 2001; 276: 11041–11048
   PubMed Web of Science ®Google Scholar
• Gutterman JU. Cytokine therapeutics: Lessons from interferon alpha. Proc Natl Acad Sci USA 1994; 91: 1198–1205
   PubMed Web of Science ®Google Scholar
• Hama K, Ohnishi H, Aoki H, Kita H, Yamamoto H, Osawa H, et al. Angiotensin II promotes the proliferation of activated pancreatic stellate cells by Smad7 induction through a protein kinase C pathway. Biochem Biophys Res Commun 2006; 340: 742–750
   PubMedGoogle Scholar
• Higashi K, Inagaki Y, Fujimori K, Nakao A, Kaneko H, Nakatsuka I. Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3. J Biol Chem 2003; 278: 43470–43479
   PubMed Web of Science ®Google Scholar
• Hortelano S, Dewez B, Genaro AM, az-Guerra MJ, Bosca L. Nitric oxide is released in regenerating liver after partial hepatectomy. Hepatology 1995; 21: 776–786
   PubMed Web of Science ®Google Scholar
• Inagaki Y, Nemoto T, Kushida M, Sheng Y, Higashi K, Ikeda K, et al. Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice. Hepatology 2003; 38: 890–899
   PubMed Web of Science ®Google Scholar
• Isaacs A, Lindenmann J. Virus interference. I. The interferon. Proc R Soc Lond B Biol Sci 1957; 147: 258–267
   PubMed Web of Science ®Google Scholar
• Ishida Y, Kondo T, Takayasu T, Iwakura Y, Mukaida N. The essential involvement of cross-talk between IFN-gamma and TGF-beta in the skin wound-healing process. J Immunol 2004; 172: 1848–1855
   PubMed Web of Science ®Google Scholar
• Jeong WI, Park O, Radaeva S, Gao B. STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity. Hepatology 2006; 44: 1441–1451
   PubMed Web of Science ®Google Scholar
• Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, et al. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. Mol Cell 2000; 6: 1365–1375
   PubMed Web of Science ®Google Scholar
• Kim SJ, Im YH, Markowitz SD, Bang YJ. Molecular mechanisms of inactivation of TGF-beta receptors during carcinogenesis. Cytokine Growth Factor Rev 2000; 11: 159–168
   PubMedGoogle Scholar
• Lei X, Yang J, Nichols RW, Sun LZ. Abrogation of TGFbeta signaling induces apoptosis through the modulation of MAP kinase pathways in breast cancer cells. Exp Cell Res 2007; 313: 1687–1695
   PubMed Web of Science ®Google Scholar
• Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265–275
   PubMed Web of Science ®Google Scholar
• Massague J, Blain SW, Lo RS. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 2000; 103: 295–309
   PubMed Web of Science ®Google Scholar
• Park DY, Lee CH, Sol MY, Suh KS, Yoon SY, Kim JW. Expression and localization of the transforming growth factor-beta type I receptor and Smads in preneoplastic lesions during chemical hepatocarcinogenesis in rats. J Korean Med Sci 2003; 18: 510–519
   PubMedGoogle Scholar
• Parody JP, Alvarez ML, Quiroga A, Ronco MT, Frances D, Carnovale C, et al. Hepatocytes isolated from preneoplastic rat livers are resistant to ethacrynic acid cytotoxicity. Arch Toxicol 2007; 81: 565–573
   PubMed Web of Science ®Google Scholar
• Platanias LC. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 2005; 5: 375–386
   PubMed Web of Science ®Google Scholar
• Quiroga AD, Alvarez ML, Parody JP, Ronco MT, Frances DE, Pisani GB, et al. Involvement of reactive oxygen species on the apoptotic mechanism induced by IFN-alpha2b in rat preneoplastic liver. Biochem Pharmacol 2007; 73: 1776–1785
   PubMed Web of Science ®Google Scholar
• Roberts AB, Wakefield LM. The two faces of transforming growth factor beta in carcinogenesis. Proc Natl Acad Sci USA 2003; 100: 8621–8623
   PubMed Web of Science ®Google Scholar
• Seglen PO. Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion. Exp Cell Res 1973; 82: 391–398
   PubMed Web of Science ®Google Scholar
• Tahashi Y, Matsuzaki K, Date M, Yoshida K, Furukawa F, Sugano Y, et al. Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury. Hepatology 2002; 35: 49–61
   PubMed Web of Science ®Google Scholar
• Tsunobuchi H, Ishisaki A, Imamura T. Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells. Biochem Biophys Res Commun 2004; 316: 712–719
   PubMed Web of Science ®Google Scholar
• Ulloa L, Doody J, Massague J. Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. Nature 1999; 397: 710–713
   PubMed Web of Science ®Google Scholar
• Weng H, Mertens PR, Gressner AM, Dooley S. IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads. J Hepatol 2007; 46: 295–303
   PubMed Web of Science ®Google Scholar
• Williams BR, Haque SJ. Interacting pathways of interferon signaling. Semin Oncol 1997; 24: S9
   Google Scholar
• Yamamoto T, Matsuda T, Muraguchi A, Miyazono K, Kawabata M. Cross-talk between IL-6 and TGF-beta signaling in hepatoma cells. FEBS Lett 2001; 492: 247–253
   PubMed Web of Science ®Google Scholar