Transplantation of apoptosis-resistant embryonic stem cells into the injured rat spinal cord

References

• Adams LD, Choi L, Xian HQ, Yang A, Sauer B, Wei L, Gottlieb DI. 2003. Double lox targeting for neural cell transgenesis. Brain Research Molecular Brain Research 110:220–233.
   PubMedGoogle Scholar
• Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI. 1995. Embryonic stem cells express neuronal properties in vitro. Development Biology 168:342–357.
   PubMed Web of Science ®Google Scholar
• Beddington RS, Robertson EJ. 1989. An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo. Development 105:733–737.
   PubMed Web of Science ®Google Scholar
• Blight AR. 1985. Delayed demyelination and macrophage invasion: A candidate for secondary cell damage in spinal cord injury. Central Nervous System Trauma 2:299–315.
   PubMedGoogle Scholar
• Bradley A, Evans M, Kaufman MH, Robertson E. 1984. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309:255–256.
   PubMed Web of Science ®Google Scholar
• Bunge RP, Puckett WR, Becerra JL, Marcillo A, Quencer RM. 1993. Observations on the pathology of human spinal cord injury. A review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination. Advances in Neurology 59:75–89.
   PubMedGoogle Scholar
• Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS. 1997. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nature Medicine 3:73–76.
   PubMed Web of Science ®Google Scholar
• Doetschman TC, Eistetter H, Katz M, Schmidt W, Kemler R. 1985. The in vitro development of blastocyst-derived embryonic stem cell lines: Formation of visceral yolk sac, blood islands and myocardium. Journal of Embryology Experimental Morphology 87:27–45.
   PubMedGoogle Scholar
• Evans MJ, Kaufman MH. 1981. Establishment in culture of pluripotential cells from mouse embryos. Nature 292:154–156.
   PubMed Web of Science ®Google Scholar
• Hadjantonakis A, Papaioannou V. 2001. The stem cells of early embryos. Differentiation 68:159–166.
   PubMedGoogle Scholar
• Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, Verfaillie CM. 2002. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418:41–49.
   PubMed Web of Science ®Google Scholar
• Koh CJ, Atala A. 2004. Tissue engineering, stem cells, and cloning: Opportunities for regenerative medicine. Journal of American Society of Nephrology 15:1113–1125.
   PubMed Web of Science ®Google Scholar
• Liu XZ, Xu XM, Hu R, Du C, Zhang SX, McDonald JW, Dong HX, Wu YJ, Fan GS, Jacquin MF, Hsu CY, Choi DW. 1997. Neuronal and glial apoptosis after traumatic spinal cord injury. Journal of Neuroscience 17:5395–5406.
   PubMed Web of Science ®Google Scholar
• Martin GR. 1981. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proceedings of the National Academy of Sciences of the United State of America 78:7634–7638.
   PubMed Web of Science ®Google Scholar
• McDonald JW, Liu XZ, Qu Y, Liu S, Mickey SK, Turetsky D, Gottlieb DI, Choi DW. 1999. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nature Medicine 5:1410–1412.
   PubMed Web of Science ®Google Scholar
• McDonald JW, Howard MJ. 2002. Repairing the damaged spinal cord: A summary of our early success with embryonic stem cell transplantation and remyelination. Progress in Brain Research 137:299–309.
   PubMed Web of Science ®Google Scholar
• McDonald JW, Becker D, Holekamp TF, Howard M, Liu S, Lu A, Lu J, Platik MM, Qu Y, Stewart, T, Vadivelu S. 2004. Repair of the injured spinal cord and the potential of embryonic stem cell transplantation. Journal of Neurotrauma 21:383–393.
   PubMed Web of Science ®Google Scholar
• Murray M. 2004. Cellular transplants: Steps toward restoration of function in spinal injured animals. Progress in Brain Research 143:133–146.
   PubMed Web of Science ®Google Scholar
• Norenberg MD, Smith J, Marcillo A. 2004. The pathology of human spinal cord injury: Defining the problems. Journal of Neurotrauma 21:429–440.
   PubMed Web of Science ®Google Scholar
• Rippon HJ, Bishop AE. 2004. Embryonic stem cells. Cell Proliferation 37:23–34.
   PubMed Web of Science ®Google Scholar
• Shuman SL, Bresnahan JC, Beattie MS. 1997. Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats. Journal of Neuroscience Research 50:798–808.
   PubMed Web of Science ®Google Scholar
• Snyder EY, Kim SU. 1979. Hormonal requirements for neuronal survival in culture. Neuroscience Letters 13:225–230.
   PubMedGoogle Scholar
• Snyder EY, Daley GQ, Goodell M. 2004. Taking stock and planning for the next decade: Realistic prospects for stem cell therapies for the nervous system. Journal of Neuroscience Research 76:157–168.
   PubMedGoogle Scholar
• Sylvester KG, Longaker MT. 2004. Stem cells: Review and update. Archives of Surgery 139:93–99.
   PubMedGoogle Scholar
• Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. 1998. Embryonic stem cell lines derived from human blastocysts. Science 282:1145–1147.
   PubMed Web of Science ®Google Scholar
• Waxman SG. 1989. Demyelination in spinal cord injury. Journal of the Neurological Sciences 91:1–14.
   PubMed Web of Science ®Google Scholar
• Waxman SG. 1992. Demyelination in spinal cord injury and multiple sclerosis: What can we do to enhance functional recovery? Journal of Neurotrauma 9(Suppl 1):S105–S117.
   Google Scholar
• Waxman SG, Utzschneider DA, Kocsis JD. 1994. Enhancement of action potential conduction following demyelination: Experimental approaches to restoration of function in multiple sclerosis and spinal cord injury. Progress in Brain Research 100:233–243.
   PubMedGoogle Scholar
• Wurmser AE, Gage FH. 2002. Stem cells: Cell fusion causes confusion. Nature 416:485–487.
   PubMed Web of Science ®Google Scholar