Ocular Inflammatory Responses in the EP₂ and EP₄ Receptor Knockout Mice

REFERENCES

• Bhattacherjee P, Hammond B R. Inhibition of increased permeability of the blood-aqueous barrier by non-steroidal anti-inflammatory compounds as demonstrated by fluorescein angiography. Exp Eye Res 1975; 21(6)499–505, [INFOTRIEVE], [CSA]
   Google Scholar
• Unger W G, Cole D F, Bass M S. Prostaglandin and neurologically mediated ocular response to laser irradiation of the rabbit iris. Exp Eye Res 1977; 25(3)209–220, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Rahi A, Bhattacherjee P, Misra R. Release of prostaglandins in experimental immune complex endophthalmitis and phacoallergic uveitis. Br J Ophthalmol 1978; 62(2)105–109, [CSA]
   Google Scholar
• Miller J D, Eakins K E, Atwal M. The release of PGE2-like activity into aqueous humor after paracentesis and its prevention by aspirin. Invest Ophthalmol 1973; 12(12)939–942, [INFOTRIEVE], [CSA]
   Google Scholar
• Neufeld A H, Jampol L M, Sears M L. Aspirin prevents the disruption of the blood-aqueous barrier in the rabbit eye. Nature 1972; 238(5360)158–159, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Camras C B, Bito L Z, Eakins K E. Reduction of intraocular pressure by prostaglandins applied topically to the eyes of conscious rabbits. Invest Ophthalmol Visual Sci 1977; 16(12)1125–1134, [CSA]
   PubMed Web of Science ®Google Scholar
• Bito L Z, Wallenstein M C. Transport of prostaglandins across the blood-brain and blood-aqueous barriers and the physiological significance of these absorptive transport processes. Exp Eye Res 1977; 25(Suppl.)229–243, [INFOTRIEVE], [CSA]
   Google Scholar
• Stjernschantz J, Selen G, Sjoquist B, Resul B. Preclinical pharmacology of latanoprost, a phenyl-substituted PGF2 alpha analogue. Adv Prostaglandin Thromboxane Leukotr Res 1995; 23: 513–518, [CSA]
   PubMedGoogle Scholar
• Alm A, Villumsen J. PhXA34, a new potent ocular hypotensive drug. A study on dose-response relationship and on aqueous humor dynamics in healthy volunteers. Arch Ophthalmol 1991; 109(11)1564–1568, [PUBMED], [INFOTRIEVE], [CSA]
   Google Scholar
• Alm A, Camras C B, Watson P G. Phase III latanoprost studies in Scandinavia, the United Kingdom and the United States. Surv Ophthalmol 1997; 41(Suppl 2)S105–110, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Hellberg M R, McLaughlin M A, Sharif N A, DeSantis L, Dean T R, Kyba E P, Bishop J E, Klimko P G, Zinke P W, Selliah R D, Barnes G, DeFaller J, Kothe A, Landry T, Sullivan E K, Andrew R, Davis A A, Silver L, Bergamini M V, Robertson S, Weiner A L, Sallee V L. Identification and characterization of the ocular hypotensive efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist, and AL-6598, a DP prostaglandin receptor agonist. Surv Ophthalmol 2002; 47(Suppl 1)S13–33, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Bhattacherjee P, Jacobs N, Coca-Prados M, Paterson C. Identification of prostanoid receptors in rabbit non-pigmented ciliary epithelial cells. Exp Eye Res 1996; 62(5)491–498, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Jumblatt M M, Paterson C A. Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype. Invest Ophthalmol Visual Sci 1991; 32(2)360–365, [CSA]
   Google Scholar
• Jumblatt M M, Neltner A A, Coca-Prados M, Paterson C A. EP2-receptor stimulated cyclic AMP synthesis in cultured human non-pigmented ciliary epithelium. Exp Eye Res 1994; 58(5)563–566, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Csukas S, Bhattacherjee P, Rhodes L, Paterson C A. Prostaglandin E2 binding site distribution and subtype classification in the rabbit iris-ciliary body. Prostaglandins 1992; 44(3)199–208, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Csukas S, Bhattacherjee P, Rhodes L, Paterson C A. Prostaglandin E2 and F2 alpha binding sites in the bovine iris ciliary body. Invest Ophthalmol Visual Sci 1993; 34(7)2237–2245, [CSA]
   Google Scholar
• Liu L, Eta E, Bhattacherjee P, Paterson C A. Comparative studies on prostanoid receptors in human non-pigmented ciliary epithelial and mouse fibroblast cell lines. Prostaglandins Leukotr Essent Fatty Acids 1996; 55(4)231–240, [CROSSREF], [CSA]
   Google Scholar
• Chen W, Bhattacherjee P, Paterson C A. Mobilization of intracellular calcium by prostaglandins in human ciliary muscle cells and NIH 3T3 cell line. Invest Ophthalmol Visual Sci 1996; 37: S838, [CSA]
   Google Scholar
• Mukhopadhyay P, Geoghegan T E, Patil R V, Bhattacherjee P, Paterson C A. Detection of EP2, EP4, and FP receptors in human ciliary epithelial and ciliary muscle cells. Biochem Pharmacol 1997; 53(9)1249–1255, [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Mukhopadhyay P, Bhattacherjee P, Andom T, Geoghegan T E, Andley U P, Paterson C A. Expression of prostaglandin receptors EP4 and FP in human lens epithelial cells. Invest Ophthalmol Visual Sci 1999; 40(1)105–112, [CSA]
   Google Scholar
• Mukhopadhyay P, Bian L, Yin H, Bhattacherjee P, Paterson C. Localization of EP(1) and FP receptors in human ocular tissues by in situ hybridization. Invest Ophthalmol Visual Sci 2001; 42(2)424–428, [CSA]
   PubMed Web of Science ®Google Scholar
• Yin H, Bian L, Mukhopadhyay P, Bhattacherjee P, Paterson C. Localization of EP1 and FP receptor mRNAs in human ocular tissues. Invest Ophthalmol Visual Sci 1999; 40(4)S502, [CSA]
   Google Scholar
• Biswas (Das) S, Bhattacherjee P, Paterson C A. Prostaglandin E2 receptor subtypes, EP1, EP2, EP3 and EP4 in human and mouse ocular tissues—a comparative immunohistochemical study. Prostaglandins Leukotr Essent Fatty Acids 2004, 77: 277–288, [CROSSREF], [CSA]
   Google Scholar
• Regan J W. EP2 and EP4 prostanoid receptor signaling. Life Sci 2003; 74(2–3)143–153, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Narumiya S. Prostanoids in immunity: roles revealed by mice deficient in their receptors. Life Sci 2003; 74(2–3)391–395, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Kabashima K, Saji T, Murata T, Nagamachi M, Matsuoka T, Segi E, Tsuboi K, Sugimoto Y, Kobayashi T, Miyachi Y, Ichikawa A, Narumiya S. The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut. J Clin Invest 2002; 109(7)883–893, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Kabashima K, Sakata D, Nagamachi M, Miyachi Y, Inaba K, Narumiya S. Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. Nat Med 2003; 9(6)744–749, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Kabashima K, Narumiya S. The DP receptor, allergic inflammation and asthma. Prostaglandins Leukotr Essent Fatty Acids 2003; 69(2–3)187–194, [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Xiao C Y, Yuhki K, Hara A, Fujino T, Kuriyama S, Yamada T, Takayama K, Takahata O, Karibe H, Taniguchi T, Narumiya S, Ushikubi F. Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4. Circulation 2004; 109(20)2462–2468, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Araki H, Ukawa H, Sugawa Y, Yagi K, Suzuki K, Takeuchi K. The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach. Aliment Pharmacol Ther 2000; 14(Suppl 1)116–124, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Vegge T, Neufeld A H, Sears M L. Morphology of the breakdown of the blood-aqueous barrier in the ciliary processes of the rabbit eye after prostaglandin E2. Invest Ophthalmol 1975; 14(1)33–36, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Bhattacherjee P, Hammond B R. Effect of indomethacin on the ocular hypotensive action of adrenaline in the rabbit. Exp Eye Res 1977; 24(3)307–313, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Bhattacherjee P. Prostaglandins and inflammatory reactions in the eye. Methods Findings Exp Clin Pharmacol 1980; 2(1)17–31, [CSA]
   Google Scholar
• Biswas S, Bhattacherjee P, Paterson C A. Prostaglandin E2 receptor subtypes, EP1, EP2, EP3 and EP4 in human and mouse ocular tissues—a comparative immunohistochemical study. Prostaglandins Leukotr Essent Fatty Acids 2004; 71(5)277–288, [CROSSREF], [CSA]
   Google Scholar
• Lowry O H, Rosebrough N J, Fan A L, Randall R J. Protein measurement with the folin phenol reagant. J Biol Chem 1951; 193: 265–275, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Bhattacherjee P, Mukhopadhyay P, Tilley S L, Koller B H, Geoghgan T, Paterson C A. Blood-aqueous barrier in prostaglandin EP2 receptor knockout mice. Ocul Immunol Inflamm 2002; 10(3)187–196, [INFOTRIEVE], [CROSSREF], [CSA]
   Web of Science ®Google Scholar
• Beitch B R, Eakins K E. The effects of prostaglandins on the intraocular pressure of the rabbit. Br J Pharmacol 1969; 37(1)158–167, [INFOTRIEVE], [CSA]
   Google Scholar
• Tilley S L, Audoly L P, Hicks E H, Kim H S, Flannery P J, Coffman T M, et al. Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor. J Clin Invest 1999; 103(11)1539–1545, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Tilley S L, Hartney J M, Erikson C J, Jania C, Nguyen M, Stock J, McNeisch J, Valancius C, Panettieri R A, jr, Penn R B, Koller B H. Receptors and pathways mediating the effects of prostaglandin E2 on airway tone. Am J Physiol Lung Cell Mol Physiol 2003; 284(4)L599–606, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lazzeri N, Belvisi M G, Patel H J, Chung K F, Yacoub M H, Mitchell J A. RANTES release by human airway smooth muscle: effects of prostaglandin E(2) and fenoterol. Eur J Pharmacol 2001; 433(2–3)231–235, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Jing H, Vassiliou E, Ganea D. Prostaglandin E2 inhibits production of the inflammatory chemokines CCL3 and CCL4 in dendritic cells. J Leukoc Biol 2003; 74(5)868–879, [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Tavares E, Minano F J. RANTES: a new prostaglandin dependent endogenous pyrogen in the rat. Neuropharmacology 2000; 39(12)2505–2513, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Vassiliou E, Jing H, Ganea D. Prostaglandin E2 inhibits TNF production in murine bone marrow-derived dendritic cells. Cell Immunol 2003; 223(2)120–132, [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Scandella E, Men Y, Legler D F, Gillessen S, Prikler L, Ludewig B, Groettrup M. CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2. Blood 2004; 103(5)1595–1601, [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Akaogi J, Yamada H, Kuroda Y, Nacionales D C, Reeves W H, Satoh M. Prostaglandin E2 receptors EP2 and EP4 are up-regulated in peritoneal macrophages and joints of pristane-treated mice and modulate TNF-alpha and IL-6 production. J Leukoc Biol 2004; 76(1)227–236, [INFOTRIEVE], [CROSSREF], [CSA]
   Google Scholar
• Luster A D, Tager A M. T-cell trafficking in asthma: lipid mediators grease the way. Nat Rev Immunol 2004; 4(9)711–724, [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Shinomiya S, Naraba H, Ueno A, Utsunomiya I, Maruyama T, Ohuchida S, Ushikubi F, Yuki K, Narumiya S, Sugimoto Y, Ichikawa A, Oh-ishi S. Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists. Biochem Pharmacol 2001; 61(9)1153–1160, [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar