Preliminary Report on Interleukin-22, GM-CSF, and IL-17F in the Pathogenesis of Acute Anterior Uveitis

References

• Nussenblatt RB. The natural history of uveitis. Int Ophthalmol. 1990;14(5–6):303–308. doi:10.1007/BF00163549. Epub 1990/ 10/01.PubMed PMID: 2249907.
   PubMed Web of Science ®Google Scholar
• Gritz DC, Wong IG. Incidence and prevalence of uveitis in Northern California; the Northern California epidemiology of uveitis study. Ophthalmology. 2004;111(3):491–500. discussion Epub 2004/03/17. doi:10.1016/j.ophtha.2003.06.014. PubMed PMID: 15019324.
   PubMed Web of Science ®Google Scholar
• Thorne JE, Suhler E, Skup M, et al. Prevalence of noninfectious uveitis in the United States: a claims-based analysis. JAMA Ophthalmol. 2016;134(11):1237–1245. doi:10.1001/jamaophthalmol.2016.3229. PubMed PMID: 27608193.
   PubMed Web of Science ®Google Scholar
• Brewerton DA, Webley M, Ward AM. Acute anterior uveitis and the fourteenth chromosome. Adv Inflam Res. 1985;9:225–229.
   Google Scholar
• Juanola X, Loza Santamaria E, Cordero-Coma M; Group SW. Description and prevalence of spondyloarthritis in patients with anterior uveitis: the SENTINEL interdisciplinary collaborative project. Ophthalmology. 2016;123(8):1632–1636. doi:10.1016/j.ophtha.2016.03.010. PubMed PMID: 27084561.
   PubMed Web of Science ®Google Scholar
• Robinson PC, Claushuis TA, Cortes A, et al. Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis. Arthritis Rheum. 2015;67(1):140–151. doi:10.1002/art.38873. PubMed PMID: 25200001; PMCID: PMC4302162.
   PubMed Web of Science ®Google Scholar
• Taurog JD. The role of HLA-B27 in spondyloarthritis. J Rheumatol. 2010;37(12):2606–2616. Epub 2010/12/03. doi:10.3899/jrheum.100889. PubMed PMID: 21123333.
   PubMedGoogle Scholar
• Ciccia F, Accardo-Palumbo A, Alessandro R, et al. Interleukin-22 and interleukin-22-producing NKp44+ natural killer cells in subclinical gut inflammation in ankylosing spondylitis. Arthritis Rheum. 2012;64(6):1869–1878. Epub 2012/ 01/04. doi:10.1002/art.34355. PubMed PMID: 22213179.
   PubMed Web of Science ®Google Scholar
• Ciccia F, Guggino G, Rizzo A, et al. Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis. Ann Rheum Dis. 2015;74(9):1739–1747. doi:10.1136/annrheumdis-2014-206323. PubMed PMID: 25902790.
   PubMed Web of Science ®Google Scholar
• Mauro D, Macaluso F, Fasano S, Alessandro R, Ciccia F. ILC3 in axial spondyloarthritis: the gut angle. Curr Rheumatol Rep. 2019;21(7):37. Epub 2019/ 06/15. doi:10.1007/s11926-019-0834-9. PubMed PMID: 31197599.
   PubMed Web of Science ®Google Scholar
• Rudwaleit M, van der Heijde D, Landewe R, et al. The assessment of spondyloArthritis international society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann Rheum Dis. 2011;70(1):25–31. doi:10.1136/ard.2010.133645. PubMed PMID: 21109520.
   PubMed Web of Science ®Google Scholar
• Calin A, Dijkmans B, Emery P, et al. Assessments of disease activity and functionality by enbrel-treated ankylosing spondylitis patients in a multicenter, placebo-controlled trial. Arthritis Rheum. 2003;48:S172.
   Google Scholar
• Rigby RA, Stasinopoulos DM. Generalized additive models for location, scale, and shape. J R Stat Soc, C (Applied Statistics). 2005;54:507–554.
   Web of Science ®Google Scholar
• Rosenbaum JT, Asquith M. The microbiome and HLA-B27-associated acute anterior uveitis. Nat Rev Rheumatol. 2018. Epub 2018/10/12. doi:10.1038/s41584-018-0097-2. PubMed PMID: 30301938.
   PubMed Web of Science ®Google Scholar
• Dzutsev A, Hogg A, Sui Y, et al. Differential T cell homing to colon vs. small intestine is imprinted by local CD11c(+) APCs that determine homing receptors. J Leukoc Biol. 2017;102(6):1381–1388. Epub 2017/ 09/28. doi:10.1189/jlb.1A1116-463RR. PubMed PMID: 28951425; PMCID: PMC5669635.
   PubMed Web of Science ®Google Scholar
• Krabbendam L, Nagasawa M, Spits H, Bal SM. Isolation of human innate lymphoid cells. Curr Protoc Immunol. 2018:e55. Epub 2018/06/30. doi:10.1002/cpim.55. PubMed PMID: 29957859.
   PubMedGoogle Scholar
• Ouyang W, O’Garra A. IL-10 family cytokines IL-10 and IL-22: from basic science to clinical translation. Immunity. 2019;50(4):871–891. Epub 2019/04/18. doi:10.1016/j.immuni.2019.03.020. PubMed PMID: 30995504.
   PubMed Web of Science ®Google Scholar
• Sugita S, Kawazoe Y, Imai A, et al. Role of IL-22- and TNF-alpha-producing Th22 cells in uveitis patients with Behcet’s disease. J Immunol. 2013;190(11):5799–5808. Epub 2013/05/01. doi:10.4049/jimmunol.1202677. PubMed PMID: 23630362; PMCID: PMC3659956.
   PubMed Web of Science ®Google Scholar
• Kim Y, Kim TW, Park YS, et al. The role of interleukin-22 and its receptor in the development and pathogenesis of experimental autoimmune uveitis. PLoS One. 2016;11(5):e0154904. Epub 2016/05/12. doi:10.1371/journal.pone.0154904. PubMed PMID: 27166675; PMCID: PMC4864334.
   PubMed Web of Science ®Google Scholar
• Bhuyan ZA, Asanoma M, Iwata A, et al. Abrogation of Rbpj attenuates experimental autoimmune uveoretinitis by inhibiting IL-22-producing CD4+ T cells. PLoS One. 2014;9(2):e89266. Epub 2014/ 03/04. doi:10.1371/journal.pone.0089266. PubMed PMID: 24586644; PMCID: PMC3938452.
   PubMed Web of Science ®Google Scholar
• Sugita S, Kawazoe Y, Imai A, Usui Y, Takahashi M, Mochizuki M. Suppression of IL-22-producing T helper 22 cells by RPE cells via PD-L1/PD-1 interactions. Invest Ophthalmol Vis Sci. 2013;54(10):6926–6933. Epub 2013/09/26. doi:10.1167/iovs.13-12703. PubMed PMID: 24065812.
   PubMed Web of Science ®Google Scholar
• Chen W, Zhao B, Jiang R, et al. Cytokine expression profile in aqueous humor and sera of patients with acute anterior uveitis. Curr Mol Med. 2015;15:(6):543–549. doi:10.2174/1566524015666150731100012. Epub 2015/08/05.PubMed PMID: 26238370.
   PubMed Web of Science ®Google Scholar
• Abu El-Asrar AM, Berghmans N, Al-Obeidan SA, et al. Expression of interleukin (IL)-10 family cytokines in aqueous humour of patients with specific endogenous uveitic entities: elevated levels of IL-19 in human leucocyte antigen-B27-associated uveitis. Acta Ophthalmol. 2019;97(5):e780–e4. Epub 2019/ 02/15. doi:10.1111/aos.14039. PubMed PMID: 30761764.
   PubMed Web of Science ®Google Scholar
• Baeten D, Baraliakos X, Braun J, et al. Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial. Lancet. 2013;382(9906):1705–1713. doi:10.1016/S0140-6736(13)61134-4. PubMed PMID: 24035250.
   PubMed Web of Science ®Google Scholar
• Kezic JM, Glant TT, Rosenbaum JT, Rosenzweig HL. Neutralization of IL-17 ameliorates uveitis but damages photoreceptors in a murine model of spondyloarthritis. Arthritis Res Ther. 2012;14(1):R18. Epub 2012/ 01/25. ar3697 [pii]. doi:10.1186/ar3697. PubMed PMID: 22269151; PMCID: PMC3392808.
   PubMed Web of Science ®Google Scholar
• Kaufmann U, Diedrichs-Mohring M, Wildner G. Dynamics of intraocular IFN-gamma, IL-17 and IL-10-producing cell populations during relapsing and monophasic rat experimental autoimmune uveitis. PLoS One. 2012;7(11):e49008. doi:10.1371/journal.pone.0049008. PubMed PMID: 23155443; PMCID: 3498374.
   PubMed Web of Science ®Google Scholar
• Letko E, Yeh S, Foster CS, Pleyer U, Brigell M, Grosskreutz CL; Group AAS. Efficacy and safety of intravenous secukinumab in noninfectious uveitis requiring steroid-sparing immunosuppressive therapy. Ophthalmology. 2015;122(5):939–948. doi:10.1016/j.ophtha.2014.12.033. PubMed PMID: 25638011.
   PubMed Web of Science ®Google Scholar
• Dick AD, Tugal-Tutkun I, Foster S, et al. Secukinumab in the treatment of noninfectious uveitis: results of three randomized, controlled clinical trials. Ophthalmology. 2013;120(4):777–787. Epub 2013/ 01/08. doi:10.1016/j.ophtha.2012.09.040. PubMed PMID: 23290985.
   PubMed Web of Science ®Google Scholar
• Reis J, Vender R, Torres T. Bimekizumab: the first dual inhibitor of interleukin (IL)-17A and IL-17F for the treatment of psoriatic disease and ankylosing spondylitis. BioDrugs. 2019. Epub 2019/ 06/07. doi:10.1007/s40259-019-00361-6. PubMed PMID: 31172372.
   PubMed Web of Science ®Google Scholar
• Taylor PC, Saurigny D, Vencovsky J, et al. Efficacy and safety of namilumab, a human monoclonal antibody against granulocyte-macrophage colony-stimulating factor (GM-CSF) ligand in patients with rheumatoid arthritis (RA) with either an inadequate response to background methotrexate therapy or an inadequate response or intolerance to an anti-TNF (tumour necrosis factor) biologic therapy: a randomized, controlled trial. Arthritis Res Ther. 2019;21(1):101. doi:10.1186/s13075-019-1879-x. PubMed PMID: 30999929; PMCID: PMC6471864.
   PubMed Web of Science ®Google Scholar
• Crotti C, Biggioggero M, Becciolini A, Agape E, Favalli EG. Mavrilimumab: a unique insight and update on the current status in the treatment of rheumatoid arthritis. Expert Opin Investig Drugs. 2019;28(7):573–581. Epub 2019/06/19. doi:10.1080/13543784.2019.1631795. PubMed PMID: 31208237.
   PubMed Web of Science ®Google Scholar
• Meermeier EW, Harriff MJ, Karamooz E, Lewinsohn DM. MAIT cells and microbial immunity. Immunol Cell Biol. 2018;96(6):607–617. Epub 2018/02/17. doi:10.1111/imcb.12022. PubMed PMID: 29451704; PMCID: PMC6045460.
   PubMed Web of Science ®Google Scholar
• Rosenbaum JT, Dick AD. The eyes have it: a rheumatologist’s view of uveitis. Arthritis Rheum. 2018;70(10):1533–1543. Epub 2018/ 05/24. doi:10.1002/art.40568. PubMed PMID: 29790291; PMCID: PMC6160350.
   Web of Science ®Google Scholar
• Verhagen FH, Hiddingh S, Rijken R, et al. High-dimensional profiling reveals heterogeneity of the Th17 subset and its association with systemic immunomodulatory treatment in non-infectious uveitis. Front Immunol. 2018;9:2519. Epub 2018/11/16. doi:10.3389/fimmu.2018.02519. PubMed PMID: 30429855; PMCID: PMC6220365.
   PubMed Web of Science ®Google Scholar
• Chateau T, Bonovas S, Le Berre C, Mathieu N, Danese S, Peyrin-Biroulet L. Vedolizumab treatment in extra-intestinal manifestations in inflammatory bowel disease: a systematic review. J Crohn’s & colitis. 2019. Epub 2019/05/12. doi:10.1093/ecco-jcc/jjz095. PubMed PMID: 31076751.
   PubMedGoogle Scholar