265
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Treatment of Refractory Cystoid Macular Edema with Pegylated Interferon Alfa-2A: A Retrospective Chart Review

, MD, , MD, PhD, , MD, , MD, , MD & , MD, MPH
Pages 566-571 | Received 16 Nov 2018, Accepted 28 Oct 2019, Published online: 19 Nov 2019

References

  • Lardenoye C, Van Kooij B, Rothova A. Impact of macular edema on visual acuity in uveitis. Ophthalmology. 2006;113:1446–1449. doi:10.1016/j.ophtha.2006.03.027.
  • Yalçindağ FN, Uzun A. Results of interferon alpha-2a therapy in patients with Behcet’s disease. J Ocul Pharmacol Ther. 2012;28(4):439–443. doi:10.1089/jop.2011.0238.
  • Onal S, Kazokoglu H, Koc A, et al. Long-term efficacy and safety of low-dose and dose-escalating interferon alfa-2a therapy in refractory Behçet uveitis. Arch Ophthalmol. 2011;129(3):288–294. doi:10.1001/archophthalmol.2011.3.
  • Plskova J, Greiner K, Forrester JV. Interferon-alpha as an effective treatment for noninfectious posterior uveitis and panuveitis. Am J Ophthalmol. 2007;144:55–61. doi:10.1016/j.ajo.2007.03.050.
  • Fardeau C, Simon A, Rodde B, et al. Interferon-alpha2a and systemic corticosteroid in monotherapy in chronic uveitis: results of the randomized controlled BIRDFERON study. Am J Ophthalmol. 2017;177:182–194. doi:10.1016/j.ajo.2017.03.001.
  • Deuter C, Kotter I, Gunaydin I. Efficacy and tolerability of interferon alpha treatment in patients with chronic cystoid macular oedema due to non-infectious uveitis. Br J Ophthalmol. 2009;93:906–913. doi:10.1136/bjo.2008.153874.
  • Deuter C, Kotter I, Gunaydin I, et al. Interferon alfa-2a: A new treatment option for long lasting refractory cystoid macular edema in uveitis? A pilot study. Retina. 2006;26:786–791. doi:10.1097/01.iae.0000244265.75771.71.
  • Lightman S, Taylor SRJ, Bunce C, et al. Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet’s disease with upregulation of circulating regulatory T cells and reduction of Th17. Ann Rheum Dis. 2015;74(6):1138–1144. doi:10.1136/annrheumdis-2014-205571.
  • Bielefeld P, Devilliers H, Deschasse C, et al. Potential of pegylated interferon alpha-2a in Behçet uveitis: a report of five cases. Ocul Immunol Inflamm. 2015;24:1–4. doi:10.3109/09273948.2015.1010652.
  • Bodaghi B, Gendron G, Wechsler B, et al. Efficacy of interferon alpha in the treatment of refractory and sight threatening uveitis: a retrospective monocentric study of 45 patients. Br J Ophthalmol. 2007;91:335–339. doi:10.1136/bjo.2006.101550.
  • Mackensen F, Jakob E, Springer C, et al. Interferon versus methotrexate in intermediate uveitis with macular edema: results of a randomized controlled clinical trial. Am J Ophthalmol. 2013;156(3):478–486. doi:10.1016/j.ajo.2013.05.002.
  • Taraborelli M, Cavazzana I, Fredi M, et al. Treatment and functional outcome of patients with cystoid macular edema: a single-center experience. Clin Rheumatol. 2015;34(4):791–794. doi:10.1007/s10067-014-2694-z.
  • Levin MH, Pistilli M, Daniel E, et al. Incidence of visual improvement in uveitis cases with visual impairment caused by macular edema. Ophthalmology. 2014;121(2):588–595. doi:10.1016/j.ophtha.2013.09.023.
  • Tranos PG, Tsaousis KT, Vakalis AN, et al. Long-term follow-up of inflammatory cystoid macular edema. Retina. 2012;32(8):1624–1628. doi:10.1097/IAE.0b013e3182483348.
  • Deuter C, Zierhut M, Mohle A, et al. Long-term remission after cessation of interferon-alpha treatment in patients with severe uveitis due to Behcet’s disease. Arthritis Rheum. 2010;62:2796–2805. doi:10.1002/art.27581.
  • Agarwal SK, Bhowmik D, Mahajan S, et al. Pegylated interferon monotherapy for hepatitis C virus infection in patients on hemodialysis: A single center study. Indian J Nephrol. 2016;26(4):244–251. doi:10.4103/0971-4065.172228.
  • Liu CH, Liang CC, Lin JW, et al. Pegylated interferon alpha-2a versus standard interferon alpha-2a for treatment-naive dialysis patients with chronic hepatitis C: a randomized study. Gut. 2008;57:525–530. doi:10.1136/gut.2007.133884.
  • Goncalves LL, Farias AQ, Goncalves PL, et al. Branch retinal vein thrombosis and visual loss probably associated with pegylated intereferon therapy of chronic hepatitis C. World J Gastroenterol. 2006;12(28):4602–4603. doi:10.3748/wjg.v12.i28.4602.
  • Manesis EK, Petrou C, Brouzas D, et al. Optic tract neuropathy complicating low-dose interferon treatment. J Hepatol. 1994;21:474–477. doi:10.1016/S0168-8278(05)80331-9.
  • Ayaki M. Development of neovascular glaucoma in the course of interferon alfa therapy for hepatitis type C. Br J Ophthalmol. 1994;78(3):238. doi:10.1136/bjo.78.3.238-a.
  • Panetta JD, Gilani N. Interferon-induced retinopathy and its risk in patients with diabetes and hypertension undergoing treatment for chronic hepatitis C virus infection. Ailment Pharmacol Ther. 2009;30(6):597–602. doi:10.1111/apt.2009.30.issue-6.
  • Soushi S, Kobayashi F, Obazawa H, et al. Evaluation of risk factors of interferon-associated retinopathy in patients with type C chronic active hepatitis. J Jpn Ophthalmol Soc. 1996;100(1):69–76.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.