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Gynecological Endocrinology Volume 35, 2019 - Issue 1
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RUPTURED TUBAL ECTOPIC PREGNANCY AND METHOTREXATE TREATMENT

Risk factors and human chorionic gonadotropin trends in patients with ruptured tubal ectopic pregnancies despite methotrexate treatment

Anne P. HutchinsonDepartment of Obstetrics and Gynecology, Weill Cornell Medical College, New York, NY, USA;
,
Nigel PereiraThe Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USACorrespondence[email protected]
,
Eric R. ChungThe Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA
,
Nirali J. ShahDepartment of Obstetrics and Gynecology, Weill Cornell Medical College, New York, NY, USA;
,
Megi ZekuThe Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA
,
Pak H. ChungThe Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA
&
Zev RosenwaksThe Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA
 show all
Pages 49-52 | Received 11 Mar 2018, Accepted 14 Jun 2018, Published online: 15 Oct 2018

References

  • American College of Obstetricians and Gynecologists. ACOG practice bulletin No. 94: medical management of ectopic pregnancy. Obstet Gynecol. 2008;111:1479–1485.
  • Barnhart KT. Clinical practice. Ectopic pregnancy. N Engl J Med. 2009;361:379–387.
  • Berg CJ, Callaghan WM, Syverson C, Henderson Z. Pregnancy-related mortality in the United States, 1998 to 2005. Obstet Gynecol. 2010;116:1302–9.
  • Practice Committee of American Society for Reproductive Medicine. Medical treatment of ectopic pregnancy: a committee opinion. Fertil Steril. 2013;100:638–44.
  • Pereira N, Gerber D, Gerber RS, et al. Effect of methotrexate or salpingectomy for ectopic pregnancy on subsequent in vitro fertilization-embryo transfer outcomes. J Minim Invasive Gynecol. 2015;22:870–6.
  • Hajenius PJ, Mol F, Mol BW, et al. Interventions for tubal ectopic pregnancy. Cochrane Database Syst Rev. 2007;1:CD000324.
  • Rodi IA, Sauer MV, Gorrill MJ, et al. The medical treatment of unruptured ectopic pregnancy with methotrexate and citrovorum rescue: preliminary experience. Fertil Steril. 1986;46:811–3.
  • Stovall TG, Ling FW, Buster JE. Outpatient chemotherapy of unruptured ectopic pregnancy. Fertil Steril. 1989;51:435–8.
  • Barnhart KT, Gosman G, Ashby R, Sammel M. The medical management of ectopic pregnancy: a meta-analysis comparing “single dose” and “multidose” regimens. Obstet Gynecol. 2003;101:778–84.
  • van Mello NM, Mol F, Ankum WM, et al. Ectopic pregnancy: how the diagnostic and therapeutic management has changed. Fertil Steril. 2012;98:1066–73.
  • Dudley PS, Heard MJ, Sangi-Haghpeykar H, et al. Characterizing ectopic pregnancies that rupture despite treatment with methotrexate. Fertil Steril. 2004;82:1374–8.
  • Heard K, Kendall J, Abbott J. Rupture of ectopic pregnancy after medical therapy with methotrexate: a case series. J Emerg Med. 1998;16:857–60.
  • Pereira N, Bender JL, Hancock K, et al. Routine monitoring of liver, renal, and hematologic tests after single- or double-dose methotrexate treatment for ectopic pregnancies after in vitro fertilization. J Minim Invasive Gynecol. 2015;22:1266–70.
  • Condous G, Okaro E, Khalid A, et al. The accuracy of transvaginal ultrasonography for the diagnosis of ectopic pregnancy prior to surgery. Hum Reprod. 2005;20:1404–9.
  • Pereira N, Pryor KP, Voskuilen-Gonzalez A, et al. Ovarian response and in vitro fertilization outcomes after salpingectomy: does salpingectomy indication matter? J Minim Invasive Gynecol. 2017;24:446–54.e1.
  • Lipscomb GH, McCord ML, Stovall TG, et al. Predictors of success of methotrexate treatment in women with tubal ectopic pregnancies. N Engl J Med. 1999;341:1974–8.
  • Mol F, Mol BW, Ankum WM, et al. Current evidence on surgery, systemic methotrexate and expectant management in the treatment of tubal ectopic pregnancy: a systematic review and meta-analysis. Hum Reprod Update. 2008;14:309–19.
  • Bonin L, Pedreiro C, Moret S, et al. Predictive factors for the methotrexate treatment outcome in ectopic pregnancy: a comparative study of 400 cases. Eur J Obstet Gynecol Reprod Biol. 2017;208:23–30.
  • Goksedef BP, Kef S, Akca A, et al. Risk factors for rupture in tubal ectopic pregnancy: definition of the clinical findings. Eur J Obstet Gynecol Reprod Biol. 2011;154:96–9.
  • Roussos D, Panidis D, Matalliotakis I, et al. Factors that may predispose to rupture of tubal ectopic pregnancy. Eur J Obstet Gynecol Reprod Biol. 2000;89:15–7.

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