References
- Zhou Y, Rui L. Leptin signaling and leptin resistance. Front Med. 2013;7:207–222.
- Bates SH, Myers MG Jr. The role of leptin receptor signaling in feeding and neuroendocrine function. Trends Endocrinol Metab. 2003;14:447–452.
- Jiang L, You J, Yu X, et al. Tyrosine-dependent and -independent actions of leptin receptor in control of energy balance and glucose homeostasis. Proc Natl Acad Sci USA. 2008;105:18619–18624.
- Tu X, Kuang Z, Gong X, et al. The influence of LepR tyrosine site mutations on mouse ovary development and related gene expression changes. PLoS One. 2015;10:e0141800.
- Adhikari D, Liu K. Molecular mechanisms underlying the activation of mammalian primordial follicles. Endocr Rev. 2009;30:438–464.
- Sengupta S, Peterson TR, Sabatini DM. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell. 2010;40:310–322.
- Holz MK, Ballif BA, Gygi SP, et al. mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell. 2005;123:569–580.
- Shahbazian D, Roux PP, Mieulet V, et al. The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. EMBO J. 2006;25:2781–2791.
- Guertin DA, Stevens DM, Thoreen CC, et al. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev Cell. 2006;11:859–871.
- Wen R, Hu S, Xiao Q, et al. Leptin exerts proliferative and anti-apoptotic effects on goose granulosa cells through the PI3K/Akt/mTOR signaling pathway. J Steroid Biochem Mol Biol. 2015;149:70–79.
- Cheng Y, Kim J, Li XX, et al. Promotion of ovarian follicle growth following mTOR activation: synergistic effects of AKT stimulators. PLoS One. 2015;10:e0117769.
- Reddy P, Liu L, Adhikari D, et al. Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science 2008;319:611–613.
- Li J, Kawamura K, Cheng Y, et al. Activation of dormant ovarian follicles to generate mature eggs. Proc Natl Acad Sci USA. 2010;107:10280–10284.
- Könner A, Brüning J. Selective insulin and leptin resistance in metabolic disorders. Cell Metab. 2012;16:144–152.
- Hiney JK, Srivastava V, Nyberg CL, et al. Insulin-like growth factor I of peripheral origin acts centrally to accelerate the initiation of female puberty. Endocrinol. 1996;137:3717–3728.
- Varela L, Horvath TL. Leptin and insulin pathways in POMC and AgRP neurons that modulate energy balance and glucose homeostasis. EMBO Rep. 2012;13:1079–1086.
- Gonzalez G. Determining the stage of the estrous cycle in female mice by vaginal smear. Cold Spring Harb Protoc. 2016;2016:8.
- Schedin P, Mitrenga T, Kaeck M. Estrous cycle regulation of mammary epithelial cell proliferation, differentiation, and death in the Sprague–Dawley rat: a model for investigating the role of estrous cycling in mammary carcinogenesis. J Mammary Gland Biol Neoplasia. 2000;5:211–225.
- Myers M, Britt KL, Wreford NG, et al. Methods for quantifying follicular numbers within the mouse ovary. Reproduction 2004;127:569–580.
- Mircea CN, Lujan ME, Jaiswal RS, et al. Ovarian imaging in the mouse using ultrasound biomicroscopy (UBM): a validation study. Reprod Fertil Dev. 2009;21:579–586.
- Pankhurst MW. A putative role for anti-Müllerian hormone (AMH) in optimising ovarian reserve expenditure. J Endocrinol. 2017;233:R1–R13.
- Richards JS, Pangas SA. New insights into ovarian function. Handb Exp Pharmacol. 2010;198:3–27.
- Steiner AZ. Biomarkers of ovarian reserve as predictors of reproductive potential. Semin Reprod Med. 2013;31:437–442.
- Reddy P, Zheng W, Liu K. Mechanisms maintaining the dormancy and survival of mammalian primordial follicles. Trends Endocrinol Metab. 2010;21:96–103.
- Wang N, Luo LL, Xu JJ, et al. Obesity accelerates ovarian follicle development and follicle loss in rats. Metab Clin Exp. 2014;63:94–103.