ILK enhances migration and invasion abilities of human endometrial stromal cells by facilitating the epithelial–mesenchymal transition

References

• Culley L, Law C, Hudson N, et al. The social and psychological impact of endometriosis on women’s lives: a critical narrative review. Hum Reprod Update. 2013;19:625–639.
   PubMed Web of Science ®Google Scholar
• Vigano P, Parazzini F, Somigliana E, et al. Endometriosis: epidemiology and aetiological factors. Best Pract Res Clin Obstet Gynaecol. 2004;18:177–200.
   PubMed Web of Science ®Google Scholar
• Sampson J. Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol. 1927;14:422–469.
   Google Scholar
• Yeung KT, Yang J. Epithelial-mesenchymal transition in tumor metastasis. Mol Oncol. 2017;11:28–39.
   PubMed Web of Science ®Google Scholar
• Wei SC, Yang J. Forcing through tumor metastasis: the interplay between tissue rigidity and epithelial-mesenchymal transition. Trends Cell Biol. 2016;26:111–120.
   PubMed Web of Science ®Google Scholar
• Matsuzaki S, Darcha C. Epithelial to mesenchymal transition-like and mesenchymal to epithelial transition-like processes might be involved in the pathogenesis of pelvic endometriosis. Hum Reprod. 2012;27:712–721.
   PubMed Web of Science ®Google Scholar
• Proestling K, Birner P, Gamperl S, et al. Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis. Reprod Biol Endocrinol. 2015;13:75.
   PubMed Web of Science ®Google Scholar
• Zheng Q, Xu Y, Lu J, et al. Emodin inhibits migration and invasion of human endometrial stromal cells by facilitating the mesenchymal-epithelial transition through targeting ILK. Reprod Sci. 2016;23:1526–1535.
   PubMed Web of Science ®Google Scholar
• Zheng QM, Lu JJ, Zhao J, et al. Periostin facilitates the epithelial-mesenchymal transition of endometrial epithelial cells through ILK-Akt signaling pathway. Biomed Res Int. 2016;2016:1.
   Web of Science ®Google Scholar
• Wu C, Dedhar S. Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. J Cell Biol. 2001;155:505–510.
   PubMed Web of Science ®Google Scholar
• McDonald PC, Fielding AB, Dedhar S. Integrin-linked kinase–essential roles in physiology and cancer biology. J Cell Sci. 2008;121:3121–3132.
   PubMed Web of Science ®Google Scholar
• Zhuang X, Lv M, Zhong Z, et al. Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways. J Exp Clin Cancer Res. 2016;35:130.
   PubMed Web of Science ®Google Scholar
• Chen D, Zhang Y, Zhang X, et al. Overexpression of integrin-linked kinase correlates with malignant phenotype in non-small cell lung cancer and promotes lung cancer cell invasion and migration via regulating epithelial-mesenchymal transition (EMT)-related genes. Acta Histochem. 2013;115:128–136.
   PubMed Web of Science ®Google Scholar
• Yan Z, Yin H, Wang R, et al. Overexpression of integrin-linked kinase (ILK) promotes migration and invasion of colorectal cancer cells by inducing epithelial-mesenchymal transition via NF-kappaB signaling. Acta Histochem. 2014;116:527–533.
   PubMed Web of Science ®Google Scholar
• Gil D, Ciołczyk-Wierzbicka D, Dulińska-Litewka J, et al. Integrin-linked kinase regulates cadherin switch in bladder cancer. Tumor Biol. 2016;37:15185–15191.
   PubMedGoogle Scholar
• Xing Y, Qi J, Deng S, et al. Small interfering RNA targeting ILK inhibits metastasis in human tongue cancer cells through repression of epithelial-to-mesenchymal transition. Exp Cell Res. 2013;319:2058–2072.
   PubMed Web of Science ®Google Scholar
• Xu X, Zheng Q, Zhang Z, et al. Periostin enhances migration, invasion, and adhesion of human endometrial stromal cells through integrin-linked kinase 1/Akt signaling pathway. Reprod Sci. 2015;22:1098–1106.
   PubMed Web of Science ®Google Scholar
• Liu H, Zhang Z, Xiong W, et al. Hypoxia-inducible factor-1alpha promotes endometrial stromal cells migration and invasion by upregulating autophagy in endometriosis. Reproduction. 2017;153:809–820.
   PubMed Web of Science ®Google Scholar
• Zhan H, Ma J, Ruan F, et al. Elevated phosphatase of regenerating liver 3 (PRL-3) promotes cytoskeleton reorganization, cell migration and invasion in endometrial stromal cells from endometrioma. Hum Reprod. 2016;31:723–733.
   PubMed Web of Science ®Google Scholar
• Liu H, Jiang Y, Jin X, et al. CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity. Reprod Biol Endocrinol. 2013;11:64.
   PubMed Web of Science ®Google Scholar
• Guan YT, Huang YQ, Wu JB, et al. Overexpression of chloride channel-3 is associated with the increased migration and invasion ability of ectopic endometrial cells from patients with endometriosis. Hum Reprod. 2016;31:986–998.
   PubMed Web of Science ®Google Scholar
• Zhao M, Gao Y, Wang L, et al. Overexpression of integrin-linked kinase promotes lung cancer cell migration and invasion via NF-kappaB-mediated upregulation of matrix metalloproteinase-9. Int J Med Sci. 2013;10:995–1002.
   PubMed Web of Science ®Google Scholar
• Piao Z, Hong CS, Jung MR, et al. Thymosin beta4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/beta-catenin signaling pathway. Biochem Biophys Res Commun. 2014;452:858–864.
   PubMed Web of Science ®Google Scholar
• Shirley LA, McCarty S, Yang MC, et al. Integrin-linked kinase affects signaling pathways and migration in thyroid cancer cells and is a potential therapeutic target. Surgery. 2016;159:163–170.
   PubMed Web of Science ®Google Scholar
• Ito R, Oue N, Zhu X, et al. Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma. Virchows Arch. 2003;442:118–123.
   PubMed Web of Science ®Google Scholar
• Ahmed N, Riley C, Oliva K, et al. Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid. J Pathol. 2003;201:229–237.
   PubMed Web of Science ®Google Scholar
• Liang F, Zhang S, Wang B, et al. Overexpression of integrin-linked kinase (ILK) promotes glioma cell invasion and migration and down-regulates E-cadherin via the NF-kappaB pathway. J Mol Hist. 2014;45:141–151.
   PubMed Web of Science ®Google Scholar
• Xing Y, Cui L, Kang Q. Silencing of ILK attenuates the abnormal proliferation and migration of human Tenon’s capsule fibroblasts induced by TGF-beta2. Int J Mol Med. 2016;38:407–416.
   PubMed Web of Science ®Google Scholar
• Zhu XY, Liu N, Liu W, et al. Silencing of the integrin-linked kinase gene suppresses the proliferation, migration and invasion of pancreatic cancer cells (Panc-1). Genet Mol Biol. 2012;35:538–544.
   PubMed Web of Science ®Google Scholar
• Yang YM, Yang WX. Epithelial-to-mesenchymal transition in the development of endometriosis. Oncotarget. 2017;8:41679–41689.
   PubMedGoogle Scholar
• Zhang Q, Duan J, Olson M, et al. Cellular changes consistent with epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation in the progression of experimental endometriosis in baboons. Reprod Sci. 2016;23:1409–1421.
   PubMed Web of Science ®Google Scholar
• Matsuzaki S, Darcha C, Pouly JL, et al. Effects of matrix stiffness on epithelial to mesenchymal transition-like processes of endometrial epithelial cells: Implications for the pathogenesis of endometriosis. Sci Rep. 2017;7:44616.
   PubMed Web of Science ®Google Scholar
• Shen H, Ma JL, Zhang Y, et al. Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kappaB signaling in colorectal cancer cells. World J Gastroenterol. 2016;22:3969–3977.
   PubMed Web of Science ®Google Scholar
• Han KS, Li N, Raven PA, et al. Targeting integrin-linked kinase suppresses invasion and metastasis through downregulation of epithelial-to-mesenchymal transition in renal cell carcinoma. Mol Cancer Ther. 2015;14:1024–1034.
   PubMed Web of Science ®Google Scholar
• Zhu J, Pan X, Zhang Z, et al. Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells. Cell Signal. 2012;24:1323–1332.
   PubMed Web of Science ®Google Scholar