227
Views
2
CrossRef citations to date
0
Altmetric
PC-RCT: Alpha-Lipoic Acid at combination with Mefenamic Acid in primary Dysmenorrhea

Effect of alpha-lipoic acid at the combination with mefenamic acid in girls with primary dysmenorrhea: randomized, double-blind, placebo-controlled clinical trial

, , , &
Pages 782-786 | Received 27 Aug 2018, Accepted 01 Mar 2019, Published online: 07 Apr 2019

References

  • Joshi T, Kural M, Agrawal DP, et al. Primary dysmenorrhea and its effect on quality of life in young girls. Int J Med Sci Public Health. 2015;4:381–385.
  • Akiyama S, Tanaka E, Cristeau O, et al. Evaluation of the treatment patterns and economic burden of dysmenorrhea in Japanese women, using a claims database. CEOR. 2017;9:295.
  • Saei Gharenaz M, Ozgoli M. Effect of medicinal plants in the treatment of primary dysmenorrhea in Iran: a review article. Iran J Obstetr Gynecol Infertil. 2015;18:14–31.
  • Iacovides S, Avidon I, Baker FC. What we know about primary dysmenorrhea today: a critical review. Hum Reprod Update. 2015;21:762–778.
  • Kazemi A, Bokaei M, Shirinkam F. Effect of water load on intensity of primary dysmenorrhea. 2001;11:17–21.
  • Lee H, Choi T-Y, Myung C-S, et al. Herbal medicine Shaofu Zhuyu decoction for primary dysmenorrhea: a systematic review protocol. Syst Rev. 2016;5:9.
  • Tekin YB, Güven ESG, Kirbas A, et al. The role of hypoxia at primary dysmenorrhea, utilizing a novel hypoxia marker scube1. J Pediatr Adolesc Gynecol. 2015;28:63–65.
  • Igwea SE, Tabansi-Ochuogu CS, Abaraogu UO. TENS and heat therapy for pain relief and quality of life improvement in individuals with primary dysmenorrhea: a systematic review. Complement Ther Clin Pract. 2016;24:86–91.
  • Sostres C, Gargallo CJ, Arroyo MT, et al. Adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs, aspirin and coxibs) on upper gastrointestinal tract. Best Pract Res Clin Gastroenterol. 2010;24:121–132.
  • Sadeghi N, Paknezhad F, Rashidi Nooshabadi M, et al. Vitamin E and fish oil, separately or in combination, on treatment of primary dysmenorrhea: a double-blind, randomized clinical trial. Gynecol Endocrinol. 2018;34:804–808.
  • Proctor M, Murphy PA. Herbal and dietary therapies for primary and secondary dysmenorrhoea. Cochrane Database Syst Rev. 2001;97:44.
  • Shay KP, Moreau RF, Smith EJ, et al. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta (BBA)-Gen Subj. 2009;1790:1149–1160.
  • Ziegler D, Low PA, Litchy WJ, et al. Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial. Diabetes Care. 2011;34:2054–2060.
  • Di Geronimo G, Caccese AF, Caruso L, et al. Treatment of carpal tunnel syndrome with alpha-lipoic acid. Eur Rev Med Pharmacol Sci. 2009;13:133–139.
  • Harada T, Momoeda M, Taketani Y, et al. Low-dose oral contraceptive pill for dysmenorrhea associated with endometriosis: a placebo-controlled, double-blind, randomized trial. Fertil Steril. 2008;90:1583–1588.
  • Kashanian M, Lakeh MM, Ghasemi A, et al. Evaluation of the effect of vitamin E on pelvic pain reduction in women suffering from primary dysmenorrhea. J Reprod Med. 2013;58:34–38.
  • Morrow C, Naumburg EH. Dysmenorrhea. Prim Care. 2009;36:19–32.
  • Maia H, Maltez A, Studard E, et al. Effect of the menstrual cycle and oral contraceptives on cyclooxygenase-2 expression in the endometrium. Gynecol Endocrinol. 2005;21:57–61.
  • Ha H, Lee J-H, Kim H-N, et al. alpha-Lipoic acid inhibits inflammatory bone resorption by suppressing prostaglandin E2 synthesis. J Immunol. 2006;176:111–117.
  • Mijnhout G, Alkhalaf A, Kleefstra N, et al. Alpha lipoic acid: a new treatment for neuropathic pain in patients with diabetes. Neth J Med. 2010;68:158–162.
  • Zakrzewska J, Glenny A, Forssell H. Interventions for the treatment of burning mouth syndrome (Cochrane review). Cochrane Database Syst Rev. 2001;50:125–130.
  • Gilron I, Tu D, Holden R, et al. Innovations in the management of musculoskeletal pain with alpha-lipoic acid (IMPALA trial): study protocol for a double-blind, randomized, placebo-controlled crossover trial of alpha-lipoic acid for the treatment of fibromyalgia pain. JMIR Res Protoc. 2017;66:41–45.
  • Murina F, Graziottin A, Felice R, et al. Alpha lipoic acid plus omega-3 fatty acids for vestibulodynia associated with painful bladder syndrome. J Obstetr Gynaecol Canada. 2017;39:131–137.
  • Guo Y, Jones D, Palmer JL, et al. Oral alpha-lipoic acid to prevent chemotherapy-induced peripheral neuropathy: a randomized, double-blind, placebo-controlled trial. Support Care Cancer. 2014;22:1223–1231.
  • Rochette L, Ghibu S, Muresan A, et al. Alpha-lipoic acid: molecular mechanisms and therapeutic potential in diabetes. Can J Physiol Pharmacol. 2015;93:1021–1027.
  • Mahboob A, Farhat SM, Iqbal G, et al. Alpha-lipoic acid-mediated activation of muscarinic receptors improves hippocampus-and amygdala-dependent memory. Brain Res Bull. 2016;122:19–28.
  • Akbari M, Ostadmohammadi V, Tabrizi R, et al. The effects of alpha-lipoic acid supplementation on inflammatory markers among patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trials. Nutr Metabol. 2018;15:39.
  • Carbonelli M, Renzo L, Bigioni M, et al. α-Lipoic acid supplementation: a tool for obesity therapy? CPD. 2010;16:840–846.
  • McNeilly AM, Davison GW, Murphy MH, et al. Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance. Lipids Health Dis. 2011;10:217.
  • Evans JL, Maddux BA, Goldfine ID. The molecular basis for oxidative stress-induced insulin resistance. Antioxid Redox Signal. 2005;7:1040–1052.
  • Zhang W-J, Frei B. α-Lipoic acid inhibits TNF-α-induced NF-κB activation and adhesion molecule expression in human aortic endothelial cells. FASEB J. 2001;15:2423–2432.
  • Paradells-Navarro S, Benlloch-Navarro MS, Almansa Frias MI, et al. Neuroprotection of brain cells by lipoic acid treatment after cellular stress. ACS Chem Neurosci. 2016;8:569–577.
  • Schwartz ES, Kim HY, Wang J, et al. Persistent pain is dependent on spinal mitochondrial antioxidant levels. J Neurosci. 2009;29:159–168.
  • Ziegler D, Nowak H, Kempler P, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant α‐lipoic acid: a meta‐analysis. Diabet Med. 2004;21:114–121.
  • Ziegler D, Ametov A, Barinov A, et al. Oral treatment with α-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care. 2006;29:2365–2370.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.