References
- Lizneva D, Suturina L, Walker W, et al. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016;106:6–15.
- Moghetti P. Insulin resistance and polycystic ovary syndrome. Curr Pharm Des. 2016;22:5526–5534.
- Peng Z, Sun Y, Lv X, et al. Interleukin-6 Levels in women with polycystic ovary syndrome: a systematic review and meta-analysis. PLoS One. 2016;11:e 0148531.
- Boulman N, Levy Y, Leiba R, et al. Increased C-reactive protein levels in the polycystic ovary syndrome: a marker of cardiovascular disease. J Clin Endocrinol Metab. 2004;89:2160–2165.
- Seyam E, Hasan M, Khalifa EM, et al. Evaluation of tumor necrosis factor alpha serum level in obese and lean women with clomiphene citrate-resistant polycystic ovary disease. Gynecol Endocrinol. 2017;33:892–898.
- Adams J, Liu Z, Ren YA, et al. Enhanced inflammatory transcriptome in the granulosa cells of women with polycystic ovarian syndrome. J Clin Endocrinol Metab. 2016;101:3459–3468.
- Lin YS, Tsai SJ, Lin MW, et al. Interleukin-6 as an early chronic inflammatory marker in polycystic ovary syndrome with insulin receptor substrate-2 polymorphism. Am J Reprod Immunol. 2011;66:527–533.
- Kim JH, Bachmann RA, Chen J. Interleukin-6 and insulin resistance. Vitam Horm. 2009;80:613–633.
- Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol. 2005;5:331–342.
- Price JC, Bromfield JJ, Sheldon IM. Pathogen-associated molecular patterns initiate inflammation and perturb the endocrine function of bovine granulosa cells from ovarian dominant follicles via TLR2 and TLR4 pathways. Endocrinology. 2013;154:3377–3386.
- Hardin DS, Leblanc A, Marshall G, et al. Mechanisms of insulin resistance in cystic fibrosis. Am J Physiol Endocrinol Metab. 2001;281:E1022–E1028.
- Berger M. Inflammatory mediators in cystic fibrosis lung disease. Allergy Asthma Proc. 2002;23:19–25.
- Hodges CA, Palmert MR, Drumm ML. Infertility in females with cystic fibrosis is multifactorial: evidence from mouse models. Endocrinology. 2008;149:2790–2797.
- Montanini L, Cirillo F, Smerieri A, et al. HMGB1 Is Increased by CFTR loss of function, is lowered by insulin, and increases in vivo at onset of CFRD. J Clin Endocrinol Metab. 2016;101:1274–1281.
- Wang H, Qu H, Deng H. Plasma HMGB-1 levels in subjects with obesity and type 2 diabetes: a cross-sectional study in China. PLoS One. 2015;10:e0136564.
- Ni XR, Sun ZJ, Hu GH, et al. High concentration of insulin promotes apoptosis of primary cultured rat ovarian granulosa cells via its increase in extracellular HMGB1. Reprod Sci. 2015;22:271–277.
- Smerieri A, Montanini L, Maiuri L, et al. FOXO1 content is reduced in cystic fibrosis and increases with IGF-I treatment. Int J Mol Sci. 2014;15:18000–18022.
- Chen H, Guo JH, Zhang XH, et al. Defective CFTR-regulated granulosa cell proliferation in polycystic ovarian syndrome. Reproduction. 2015;149:393–401.
- Montanini L, Smerieri A, Gullì M, et al. miR-146a, miR-155, miR-370, and miR-708 Are CFTR-dependent, predicted FOXO1 regulators and change at onset of CFRDs. J Clin Endocrinol Metab. 2016;101:4955–4963.
- Aydos A, Gure A, Islakoglu YO, et al. Identification of polycystic ovary syndrome (PCOS) specific genes in cumulus and mural granulosa cells. PLoS One. 2016;11:e0168875.
- Wang HH, Lin M, Xiang GD. Serum HMGB1 levels and its association with endothelial dysfunction in patients with polycystic ovary syndrome. Physiol Res. 2018;67:911–919.
- Dandona P, Ghanim H, Green K, et al. Insulin infusion suppresses while glucose infusion induces Toll-like receptors and high-mobility group-B1 protein expression in mononuclear cells of type 1 diabetes patients. Am J Physiol Endocrinol Metab. 2013;304:E810–E818.
- Hagiwara S, Iwasaka H, Hasegawa A, et al. Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model. Crit Care Med. 2008;36:2407–2413.
- Takikawa S, Iwase A, Goto M, et al. Assessment of the predictive value of follicular fluid insulin, leptin and adiponectin in assisted reproductive cycles. Gynecol Endocrinol. 2010;26:494–499.
- Homburg R. The management of infertility associated with polycystic ovary syndrome. Reprod Biol Endocrinol. 2003;1:109.
- Desai N, Scarrow M, Lawson J, et al. Evaluation of the effect of interleukin-6 and human extracellullar matrix on embryonic development. Hum Reprod. 1999;14:1588–1592.
- Jauniaux E, Gulbis B, Schandene L, et al. Distribution of interleukin-6 in maternal and embryonic tissues during the first trimester. Mol Hum Reprod. 1996;2:239–243.
- Demir B, Guven S, Guven ES, et al. Serum IL-6 level may have role in the pathophysiology of unexplained infertility. Am J Reprod Immunol. 2009;62:261–267.
- Prins JR, Gomez-Lopez N, Robertson SA. Interleukin-6 in pregnancy and gestational disorders. J Reprod Immunol. 2012;95:1–14.
- Li MQ, Jin LP. Ovarian stimulation for in vitro fertilization alters the protein profile expression in endometrial secretion. Int J Clin Exp Pathol. 2013;6:1964–1971.
- Baskind NE, Orsi NM, Sharma V. Impact of exogenous gonadotropin stimulation on circulatory and follicular fluid cytokine profiles. Int J Reprod Med. 2014;2014:1.
- Zhong G, Chen B. Serum and follicular fluid levels of IGF-II, IGF-binding protein-4 and pregnancy-associated plasma protein-A in controlled ovarian hyperstimulation cycle between polycystic ovarian syndrome (PCOS) and non-PCOS women. Gynecol Endocrinol. 2011;27:86–90.