Association of methylenetetrahydrofolate reductase C677T polymorphism with the pre-eclampsia risk in Hakka pregnant women in Southern China

References

• Steegers EA, von Dadelszen P, Duvekot JJ, et al. Pre-eclampsia. Lancet. 2010;376:631–644.
   PubMed Web of Science ®Google Scholar
• Magee LA, Pels A, Helewa M, et al. Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy: executive summary. J Obstet Gynaecol Can. 2014;36:416–441.
   PubMedGoogle Scholar
• Roberts JM, Cooper DW. Pathogenesis and genetics of pre-eclampsia. Lancet. 2001;357:53–56.
   PubMed Web of Science ®Google Scholar
• Dekker GA, de Vries JI, Doelitzsch PM, et al. Underlying disorders associated with severe early-onset preeclampsia. Am J Obstet Gynecol. 1995;173:1042–1048.
   PubMed Web of Science ®Google Scholar
• Powers RW, Evans RW, Majors AK, et al. Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation. Am J Obstet Gynecol. 1998;179(Pt 1):1605–1611.
   PubMed Web of Science ®Google Scholar
• Lopez-Quesada E, Vilaseca MA, Lailla JM. Plasma total homocysteine in uncomplicated pregnancy and in preeclampsia. Eur J Obstet Gynecol Reprod Biol. 2003;108:45–49.
   PubMed Web of Science ®Google Scholar
• Roberts JM, Taylor RN, Goldfien A. Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia. Am J Hypertens. 1991;4:700–708.
   PubMed Web of Science ®Google Scholar
• Cummings AM, Kavlock RJ. Gene-environment interactions: a review of effects on reproduction and development. Crit Rev Toxicol. 2004;34:461–485.
   PubMed Web of Science ®Google Scholar
• Fong FM, Sahemey MK, Hamedi G, et al. Maternal genotype and severe preeclampsia: a HuGE review. Am J Epidemiol. 2014;180:335–345.
   PubMed Web of Science ®Google Scholar
• Fabbro D, D’Elia AV, Spizzo R, et al. Association between plasminogen activator inhibitor 1 gene polymorphisms and preeclampsia. Gynecol Obstet Invest. 2003;56:17–22.
   PubMed Web of Science ®Google Scholar
• Xuan C, Lun LM. Association between the methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to preeclampsia: the need for data clarification in a recent meta-analysis. Hypertens Res. 2013;36:463–464.
   PubMed Web of Science ®Google Scholar
• Yilmaz H, Unlucerci Y, Gurdol F, et al. Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population. Aust N Z J Obstet Gynaecol. 2004;44:423–427.
   PubMed Web of Science ®Google Scholar
• Rajkovic A, Mahomed K, Rozen R, et al. Methylenetetrahydrofolate reductase 677 C –> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe. Mol Genet Metab. 2000;69:33–39.
   PubMed Web of Science ®Google Scholar
• Wang XM, Wu HY, Qiu XJ. Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism and risk of preeclampsia: an updated meta-analysis based on 51 studies. Arch Med Res. 2013;44:159–168.
   PubMed Web of Science ®Google Scholar
• Yong HE, Melton PE, Johnson MP, et al. Genome-wide transcriptome directed pathway analysis of maternal pre-eclampsia susceptibility genes. PLoS One. 2015;10:e0128230.
   PubMed Web of Science ®Google Scholar
• Jaaskelainen E, Keski-Nisula L, Toivonen S, et al. MTHFR C677T polymorphism is not associated with placental abruption or preeclampsia in Finnish women. Hypertens Pregnancy. 2006;25:73–80.
   PubMed Web of Science ®Google Scholar
• Salimi S, Saravani M, Yaghmaei M, et al. The early-onset preeclampsia is associated with MTHFR and FVL polymorphisms. Arch Gynecol Obstet. 2015;291:1303–1312.
   PubMed Web of Science ®Google Scholar
• Sohda S, Arinami T, Hamada H, et al. Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia. J Med Genet. 1997;34:525–526.
   PubMed Web of Science ®Google Scholar
• Aggarwal S, Dimri N, Tandon I, et al. Preeclampsia in North Indian women: the contribution of genetic polymorphisms. J Obstet Gynaecol Res. 2011;37:1335–1341.
   PubMed Web of Science ®Google Scholar
• Grandone E, Margaglione M, Colaizzo D, et al. Factor V Leiden, C > T MTHFR polymorphism and genetic susceptibility to preeclampsia. Thromb Haemost. 1997;77:1052–1054.
   PubMed Web of Science ®Google Scholar
• Coral-Vazquez RM, Romero Arauz JF, Canizales-Quinteros S, et al. Analysis of polymorphisms and haplotypes in genes associated with vascular tone, hypertension and oxidative stress in Mexican-Mestizo women with severe preeclampsia. Clin Biochem. 2013;46:627–632.
   PubMed Web of Science ®Google Scholar
• Williams MA, Sanchez SE, Zhang C, et al. Methylenetetrahydrofolate reductase 677 C–>T polymorphism and plasma folate in relation to pre-eclampsia risk among Peruvian women. J Matern Fetal Neonatal Med. 2004;15:337–344.
   PubMedGoogle Scholar
• Davalos IP, Moran MC, Martinez-Abundis E, et al. Methylenetetrahydrofolate reductase C677T polymorphism and Factor V Leiden variant in Mexican women with preeclampsia/eclampsia. Blood Cells Mol Dis. 2005;35:66–69.
   PubMed Web of Science ®Google Scholar
• Prasmusinto D, Skrablin S, Fimmers R, et al. Ethnic differences in the association of factor V Leiden mutation and the C677T methylenetetrahydrofolate reductase gene polymorphism with preeclampsia. Eur J Obstet Gynecol Reprod Biol. 2004;112:162–169.
   PubMed Web of Science ®Google Scholar
• Zhou L, Cheng L, He Y, et al. Association of gene polymorphisms of FV, FII, MTHFR, SERPINE1, CTLA4, IL10, and TNFalpha with pre-eclampsia in Chinese women. Inflamm Res. 2016;65:717–724.
   PubMed Web of Science ®Google Scholar
• Al-Shahrani H, Al-Dabbagh N, Al-Dohayan N, et al. Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population. BMC Ophthalmol. 2016;16:156.
   PubMed Web of Science ®Google Scholar
• Mao R, Fan Y, Chen F, et al. Methylenetetrahydrofolate reductase gene polymorphisms in 13 Chinese ethnic populations. Cell Biochem Funct. 2008;26:352–358.
   PubMed Web of Science ®Google Scholar
• Canto P, Canto-Cetina T, Juarez-Velazquez R, et al. Methylenetetrahydrofolate reductase C677T and glutathione S-transferase P1 A313G are associated with a reduced risk of preeclampsia in Maya-Mestizo women. Hypertens Res. 2008;31:1015–1019.
   PubMed Web of Science ®Google Scholar
• Aubard Y, Darodes N, Cantaloube M, et al. [Hyperhomocysteinemia and pregnancy: a dangerous association]. J Gynecol Obstet Biol Reprod (Paris). 2000;29:363–372.
   PubMedGoogle Scholar
• van der Put NM, Steegers-Theunissen RP, Frosst P, et al. Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida. Lancet. 1995;346:1070–1071.
   PubMed Web of Science ®Google Scholar
• Kluijtmans LA, van den Heuvel LP, Boers GH, et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet. 1996;58:35–41.
   PubMed Web of Science ®Google Scholar
• Aubard Y, Darodes N, Cantaloube M. Hyperhomocysteinemia and pregnancy-review of our present understanding and therapeutic implications. Eur J Obstet Gynecol Reprod Biol. 2000;93:157–165.
   PubMed Web of Science ®Google Scholar
• Tsai MY. Laboratory assessment of mild hyperhomocysteinemia as an independent risk factor for occlusive vascular diseases. Clin Chem. 1996;42:492–493.
   PubMed Web of Science ®Google Scholar
• Klai S, Fekih-Mrissa N, El Housaini S, et al. Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathies. Blood Coagul Fibrinolysis. 2011;22:374–378.
   PubMed Web of Science ®Google Scholar
• van Pampus MG, Dekker GA, Wolf H, et al. High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia. Am J Obstet Gynecol. 1999;180:1146–1150.
   PubMed Web of Science ®Google Scholar
• Hekmati Azar Mehrabani Z, Ghorbanihaghjo A, Sayyah Melli M, et al. Effects of folic acid supplementation on serum homocysteine and lipoprotein (a) levels during pregnancy. Bioimpacts. 2016;5:177–182.
   Web of Science ®Google Scholar
• Falcao S, Bisotto S, Gutkowska J, et al. Hyperhomocysteinemia is not sufficient to cause preeclampsia in an animal model: the importance of folate intake. Am J Obstet Gynecol. 2009;200:198 e1–5.
   PubMed Web of Science ®Google Scholar
• Taruscio D, Carbone P, Granata O, et al. Folic acid and primary prevention of birth defects. Biofactors. 2011;37:280–284.
   PubMed Web of Science ®Google Scholar