Effect of sulpiride on menopausal hot flashes: a randomized, double-blind, placebo-controlled clinical trial

References

• Avis NE, Crawford SL, Greendale G, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015;175:531–539.
   PubMed Web of Science ®Google Scholar
• Sturdee DW, Hunter MS, Maki PM, et al. The menopausal hot flush: a review. Climacteric. 2017;20:296–305.
   PubMed Web of Science ®Google Scholar
• Sriprasert I, Pantasri T, Piyamongkol W, et al. An international menopause society study of vasomotor symptoms in Bangkok and Chiang Mai, Thailand. Climacteric. 2017;20:171–177.
   PubMed Web of Science ®Google Scholar
• Santoro N, Epperson CN, Mathews SB. Menopausal symptoms and their management. Endocrinol Metab Clin North Am. 2015;44:497–515.
   PubMed Web of Science ®Google Scholar
• Hill DA, Crider M, Hill SR. Hormone therapy and other treatments for symptoms of menopause. Am Fam Physician. 2016;94:884–889.
   PubMed Web of Science ®Google Scholar
• Rindner L, Strömme G, Nordeman L, et al. Reducing menopausal symptoms for women during the menopause transition using group education in a primary health care setting-a randomized controlled trial. Maturitas. 2017;98:14–19.
   PubMed Web of Science ®Google Scholar
• Daley A, Stokes-Lampard H, Thomas A, et al. Exercise for vasomotor menopausal symptoms. Cochrane Database Syst Rev. 2014;11:CD006108.
   PubMed Web of Science ®Google Scholar
• Marjoribanks J, Farquhar C, Roberts H, et al. Long-term hormone therapy for perimenopausal and postmenopausal women. Cochrane Database Syst Rev. 2017;1:CD004143.
   PubMed Web of Science ®Google Scholar
• Langer RD. The evidence base for HRT: what can we believe? Climacteric. 2017;20:91–96.
   PubMed Web of Science ®Google Scholar
• Goldstein KM, McDuffie JR, Shepherd-Banigan M, et al. Nonpharmacologic, nonherbal management of menopause-associated vasomotor symptoms: an umbrella systematic review (protocol). Syst Rev. 2016;5:56.
   PubMed Web of Science ®Google Scholar
• Lethaby A, Marjoribanks J, Kronenberg F, et al. Phytoestrogens for menopausal vasomotor symptoms. Cochrane Database of Syst Rev. 2013;12:CD001395.
   Google Scholar
• Nelson HD, Vesco KK, Haney E, et al. Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis. JAMA. 2006;295:2057–2071.
   PubMed Web of Science ®Google Scholar
• Pinkerton JV, Joffe H, Kazempour K, et al. Low-dose paroxetine (7.5 mg) improves sleep in women with vasomotor symptoms associated with menopause. Menopause. 2015;22:50–58.
   PubMed Web of Science ®Google Scholar
• Stearns V, Beebe KL, Iyengar M, et al. Paroxetine controlled release in the treatment of menopausal hot flashes: a randomized controlled trial. JAMA. 2003;289:2827–2834.
   PubMed Web of Science ®Google Scholar
• Abbas AI, Hedlund PB, Huang XP, et al. Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo. Psychopharmacology (Berl). 2009;205:119–128.
   PubMed Web of Science ®Google Scholar
• World Medical Association. World medical association declaration of Helsinki ethical principles for medical research involving human subjects. JAMA. 2013;310:2191–2194.
   PubMed Web of Science ®Google Scholar
• Abramson JH. WINPEPI (PEPI-for-Windows): computer programs for epidemiologists. Epidemiol Perspect Innov. 2004;1:6.
   PubMedGoogle Scholar
• Simon JA, Chandler J, Gottesdiener K, et al. Diary of hot flashes reported upon occurrence: results of a randomized double-blind study of raloxifene, placebo, and paroxetine. Menopause. 2014;21:938–944.
   PubMed Web of Science ®Google Scholar
• Carpenter JS, Guthrie KA, Larson JC, et al. Effect of escitalopram on hot flash interference: a randomized, controlled trial. Fertil Steril. 2012;97:1399–1404.e1.
   PubMed Web of Science ®Google Scholar
• Deeks JJ, Higgins JPT, on behalf of the Statistical methods group of the Cochrane collaboration. Statistical algorithms in review manager5. 2010;5: 3–10.
   Google Scholar
• Schulz KF, Altman DG, Moher D, et al. CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Obstet Gynecol. 2010;115:1063–1070.
   PubMed Web of Science ®Google Scholar
• Linquette M, Rivière J, Vague J. [Non-hormonal therapy for menopausal disorders: results of a multicentric double-blind trial (author’s transl)]. Sem Hop. 1980;56:1445–1448.
   PubMedGoogle Scholar
• Carretti N, Florio P, Reis FM, et al. Reduction of serum serotonin precursors after veralipride treatment for postmenopausal hot flushes. Climacteric. 2010;13:141–146.
   PubMed Web of Science ®Google Scholar
• Carranza-Lira S. Actual status of veralipride use. Clin Interv Aging. 2010;5:271–276.
   PubMed Web of Science ®Google Scholar
• Valencia MH, Arias MJ, González CC, et al. Safety of veralipride for the treatment of vasomotor symptoms of menopause. Menopause. 2014;21:484–492.
   PubMed Web of Science ®Google Scholar
• Pachman DR, Jones JM, Loprinzi CL. Management of menopause-associated vasomotor symptoms: current treatment options, challenges and future directions. Int J Womens Health. 2010;2:123–135.
   PubMedGoogle Scholar
• Oakley AE, Steiner RA, Chavkin C, et al. κ Agonists as a novel therapy for menopausal hot flashes. Menopause. 2015;22:1328–1334.
   PubMed Web of Science ®Google Scholar
• Cesarani A, Alpini D, Monti B, ENT Department, University of Milan, Milan, Italy, et al. The treatment of acute vertigo. Neurol Sci. 2004;25:S26–S30.
   PubMed Web of Science ®Google Scholar
• Pérez-López FR, Abós MD. Pituitary hormonal response to the orthopramides clebopride, bromopride, metoclopramide, and sulpiride. Fertil Steril. 1982;37:445–448.
   PubMed Web of Science ®Google Scholar
• Rance NE, Dacks PA, Mittelman-Smith MA, et al. Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: a novel hypothesis on the mechanism of hot flushes. Front Neuroendocrinol. 2013;34:211–227.
   PubMed Web of Science ®Google Scholar
• Skorupskaite K, George JT, Anderson RA. The kisspeptin-GnRH pathway in human reproductive health and disease. Hum Reprod Update. 2014;20:485–500.
   PubMed Web of Science ®Google Scholar
• Li L, Xu L, Wu J, et al. Quantitative analysis of placebo response and factors associated with menopausal hot flashes. Menopause. 2017;24:932–937.
   PubMed Web of Science ®Google Scholar