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Gynecological Endocrinology Volume 36, 2020 - Issue 12
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OSTEOPOROSIS

Single-nucleotide polymorphism rs10036727 in the SLIT3 gene is associated with osteoporosis at the femoral neck in older Mexican postmenopausal women

Alberto Hidalgo-Bravoa Department of Genetics, National Institute of Rehabilitation, Mexico City, MexicoORCID Iconhttps://orcid.org/0000-0003-2506-8784View further author information
ORCID Icon,
Cristina Hernández-Medranoa Department of Genetics, National Institute of Rehabilitation, Mexico City, MexicoView further author information
,
Rosalba Sevilla-Montoyab Department of Genetics and Human Genomics, National Institute of Perinatology, Mexico City, MexicoORCID Iconhttps://orcid.org/0000-0002-5658-4661View further author information
ORCID Icon,
Berenice Rivera-Paredezc Research Center in Policies, Population and Health, School of Medicine, National Autonomous University of Mexico, Mexico City, MexicoORCID Iconhttps://orcid.org/0000-0002-9845-024XView further author information
ORCID Icon,
Eric Gustavo Ramirez-Salazard CONACYT-National Institute of Genomic Medicine (INMEGEN), Mexico City, MexicoORCID Iconhttps://orcid.org/0000-0002-0767-9357View further author information
ORCID Icon,
Jeny Flores-Moralese Genomics of Bone Metabolism Laboratory, National Institute of Genomic Medicine (INMEGEN), Mexico City, MexicoORCID Iconhttps://orcid.org/0000-0001-9082-3972View further author information
ORCID Icon,
Nelly Patiñof Subdirection of Development of Clinical Applications, National Institute of Genomic Medicine (INMEGEN), Mexico City, MexicoORCID Iconhttps://orcid.org/0000-0003-3293-2294View further author information
ORCID Icon,
Jorge Salmeronc Research Center in Policies, Population and Health, School of Medicine, National Autonomous University of Mexico, Mexico City, MexicoORCID Iconhttps://orcid.org/0000-0002-5113-299XView further author information
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Margarita Valdés-Floresa Department of Genetics, National Institute of Rehabilitation, Mexico City, MexicoCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5848-0607View further author information
ORCID Icon &
Rafael Velázquez-Cruze Genomics of Bone Metabolism Laboratory, National Institute of Genomic Medicine (INMEGEN), Mexico City, MexicoCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4515-0777View further author information
ORCID Icon show all
Pages 1096-1100 | Received 23 Mar 2020, Accepted 23 Jun 2020, Published online: 07 Aug 2020

References

  • Ma HJ, Fu SC, Xiao A, et al. The associations of cyp19a1 rs700518 polymorphism with bone mineral density and risk of osteoporosis: a meta-analysis. Gynecol.Endocrinol. 2020;36(7):626–631.
  • Gomez Dantes O, Sesma S, Becerril VM, et al. The health system of Mexico. Salud Publica Mex. 2011;53(Suppl 2):S220–S32.
  • Kanis JA, McCloskey EV, Johansson H, et al. A reference standard for the description of osteoporosis. Bone. 2008;42(3):467–475.
  • Kanis JA, Melton LJ, Christiansen C, et al. The diagnosis of osteoporosis. J Bone Miner Res. 1994;9(8):1137–1141.
  • Koromani F, Trajanoska K, Rivadeneira F, et al. Recent advances in the genetics of fractures in osteoporosis. Front Endocrinol. 2019;10:337.
  • Burge R, Dawson-Hughes B, Solomon DH, et al. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res. 2007;22(3):465–475.
  • Aziziyeh R, Amin M, Habib M, et al. The burden of osteoporosis in four Latin American Countries: Brazil, Mexico, Colombia, and Argentina. J Med Econ. 2019;22(7):638–644.
  • Peacock M, Turner CH, Econs MJ, et al. Genetics of osteoporosis. Endocr Rev. 2002;23(3):303–326.
  • Kassam S, Meyer P, Corfield A, et al. Single Nucleotide Polymorphisms (SNPs): history. CPG. 2005;3(3):237–245.
  • Gorlov IP, Gorlova OY, Sunyaev SR, et al. Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms. Am.J.Hum.Genet. 2008;82(1):100–112.
  • Yang TL, Shen H, Liu A, et al. A road map for understanding molecular and genetic determinants of osteoporosis. Nat Rev Endocrinol. 2020;16(2):91–103.
  • Estrada K, Styrkarsdottir U, Evangelou E, et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet. 2012;44(5):491–501.
  • Villalobos-Comparan M, Jimenez-Ortega RF, Estrada K, et al. A pilot genome-wide association study in postmenopausal Mexican-mestizo women implicates the rmnd1/ccdc170 locus is associated with bone mineral density. Int.J.Genomics. 2017;2017:1–13.
  • Kim BJ, Lee YS, Lee SY, et al. Osteoclast-secreted slit3 coordinates bone resorption and formation. J Clin Invest. 2018;128(4):1429–1441.
  • Kim H, Choi YJ, Lee YS, et al. SLIT3 regulates endochondral ossification by β-catenin suppression in chondrocytes. Biochem Biophys Res Commun. 2018;506(4):847–853.
  • Li N, Inoue K, Sun J, et al. Osteoclasts are not a source of SLIT3. Bone Res. 2020;8(1):11-020-0086-3. eCollection 2020.
  • Correa-Rodriguez M, Schmidt-RioValle J, Rueda-Medina B. SOX6 rs7117858 polymorphism is associated with osteoporosis and obesity-related phenotypes. Eur J Clin Invest. 2018;48(10):e13011.
  • Trajanoska K, Rivadeneira F. The genetic architecture of osteoporosis and fracture risk. Bone. 2019;126:2–10.
  • Greene CS, Penrod NM, Williams SM, et al. Failure to replicate a genetic association may provide important clues about genetic architecture. PLoS One. 2009;4(6):e5639.

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