258
Views
44
CrossRef citations to date
0
Altmetric
Original

Allopregnanolone decrease with symptom improvement during placebo and gonadotropin-releasing hormone agonist treatment in women with severe premenstrual syndrome

, , , &
Pages 257-266 | Received 16 Aug 2006, Accepted 31 Jan 2007, Published online: 07 Jul 2009

References

  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders4th ed. US Department of Health and Human Services, Washington, DC 1994; 714–718
  • Hammarbäck S, Ekholm U B, Bäckström T. Spontaneous anovulation causing disappearance of cyclical symptoms in women with the premenstrual syndrome. Acta Endocrinol (Copenh) 1991; 125: 132–137
  • Hammarbäck S, Bäckström T. Induced anovulation as treatment of premenstrual tension syndrome. A double-blind cross-over study with GnRH-agonist versus placebo. Acta Obstet. Gynecol. Scand 1988; 67: 159–166
  • Mortola J F, Girton L, Fischer U. Successful treatment of severe premenstrual syndrome by combined use of gonadotropin-releasing hormone agonist and estrogen/progestin. J Clin Endocrinol Metab 1991; 72: 252A–252F
  • Studd J, Leather A T. The need for add-back with gonadotrophin-releasing hormone agonist therapy. Br J Obstet Gynaecol 1996; 103(Suppl 14)1–4
  • Di Carlo C, Palomba S, Tommaselli G A, Guida M, Di Spiezio Sardo A, Nappi C. Use of leuprolide acetate plus tibolone in the treatment of severe premenstrual syndrome. Fertil Steril 2001; 75: 380–384
  • Rubinow D R, Hoban M C, Grover G N, Galloway D S, Roy-Byrne P, Andersen R, Merriam G R. Changes in plasma hormones across the menstrual cycle in patients with menstrually related mood disorder and in control subjects. Am J Obstet Gynecol 1988; 158: 5–11
  • Bäckström T, Sanders D, Leask R, Davidson D, Warner P, Bancroft J. Mood, sexuality, hormones, and the menstrual cycle. II. Hormone levels and their relationship to the premenstrual syndrome. Psychosom Med 1983; 6: 503–507
  • Girdler S S, Pedersen C A, Stern R A, Light K C. Menstrual cycle and premenstrual syndrome: modifiers of cardiovascular reactivity in women. Health Psychol 1993; 12: 180–192
  • Sundström I, Ashbrook D, Bäckström T. Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study. Psychoneuroendocrinology 1997; 22: 25–38
  • Sundström I, Nyberg S, Bäckström T. Patients with premenstrual syndrome have reduced sensitivity to midazolam compared to control subjects. Neuropsychopharmacology 1997; 17: 370–381
  • Sundström I, Andersson A, Nyberg S, Ashbrook D, Purdy R H, Bäckström T. Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects. Neuroendocrinology 1998; 67: 126–138
  • Nyberg S, Wahlström G, Bäckström T, Sundström-Poromaa I. Altered sensitivity to alcohol in the late luteal phase among patients with premenstrual dysphoric disorder. Psychoneuroendocrinology 2004; 29: 767–777
  • Schmidt P, Purdy R, Moore P, Jr, Paul S, Rubinow D. Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects. J Clin Endocrinol Metab 1994; 79: 1256–1260
  • Wang M, Seippel L, Purdy R H, Bäckström T. Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5α-pregnane-3,20-dione and 3α-hydroxy-5α-pregnan-20-one. J Clin Endocrinol Metab 1996; 81: 1076–1082
  • Sundström I, Bäckström T. Patients with premenstrual syndrome have decreased saccadic eye velocity compared to control subjects. Biol Psychiatry 1998; 44: 755–764
  • Rapkin A J, Morgan M, Goldman L, Brann D W, Simone D, Mahesh V B. Progesterone metabolite allopregnanolone in women with premenstrual syndrome. Obstet Gynecol 1997; 90: 709–714
  • Bicikova M, Dibbelt L, Hill M, Hampl R, Starka L. Allopregnanolone in women with premenstrual syndrome. Horm Metab Res 1998; 30: 227–230
  • Monteleone P, Luisi S, Tonetti A, Bernardi F, Genazzani A D, Luisi M, Petraglia F, Genazzani A R. Allopregnanolone concentrations and premenstrual syndrome. Eur J Endocrinol 2000; 142: 269–273
  • Lombardi I, Luisi S, Quirici B, Monteleone P, Bernardi F, Liut M, Casarosa E, Palumbo M, Petraglia F, Genazzani A R. Adrenal response to adrenocorticotropic hormone stimulation in patients with premenstrual syndrome. Gynecol Endocrinol 2004; 18: 79–87
  • Nyberg S, Andersson A, Zingmark E, Wahlström G, Bäckström T, Sundström-Poromaa I. The effect of a low dose of alcohol on allopregnanolone serum concentrations across the menstrual cycle in women with severe premenstrual syndrome and controls. Psychoneuroendocrinology 2005; 30: 892–901
  • Girdler S S, Straneva P A, Light K C, Pedersen C A, Morrow A L. Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder. Biol Psychiatry 2001; 49: 788–797
  • Freeman E W, Frye C A, Rickels K, Martin P A, Smith S S. Allopregnanolone levels and symptom improvement in severe premenstrual syndrome. J Clin Psychopharmacol 2002; 22: 516–520
  • Andréen L, Sundström-Poromaa I, Bixo M, Andersson A, Nyberg S, Bäckström T. Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone. Psychoneuroendocrinology 2005; 30: 212–224
  • Sundström I, Nyberg S, Bixo M, Hammarbäck S, Bäckström T. Treatment of premenstrual syndrome with gonadotropin-releasing hormone agonist in a low dose regimen. Acta Obstet Gynecol Scand 1999; 78: 891–899
  • Ottander U, Poromaa I S, Bjurulf E, Skytt A, Bäckström T, Olofsson J I. Allopregnanolone and pregnanolone are produced by the human corpus luteum. Mol Cell Endocrinol 2005; 239: 37–44
  • Hammarbäck S, Bäckström T, MacGibbon Tayler B. Diagnosis of premenstrual tension syndrome: description and evaluation of a procedure for diagnosis and differential diagnosis. J Psychosom Obstet Gynecol 1989; 10: 25–42
  • Purdy R H, Moore P H, Jr, Rao P N, Hagino N, Yamaguchi T, Schmidt P, Rubinow D R, Morrow A L, Paul S M. Radioimmunoassay of 3α-hydroxy-5α-pregnan-20-one in rat and human plasma. Steroids 1990; 55: 290–296
  • Timby E, Balgard M, Nyberg S, Spigset O, Andersson A, Porankiewicz-Asplund J, Purdy R H, Zhu D, Bäckström T, Poromaa I S. Pharmacokinetic and behavioral effects of allopregnanolone in healthy women. Psychopharmacology (Berl) 2005; 186: 1–11
  • Türkmen S, Löfgren M, Birzniece V, Bäckström T, Johansson I M. Tolerance development to Morris water maze test impairments induced by acute allopregnanolone. Neuroscience 2006; 139: 651–659
  • Zhu D, Birzniece V, Bäckström T, Wahlström G. Dynamic aspects of acute tolerance to allopregnanolone evaluated using anaesthesia threshold in male rats. Br J Anaesth 2004; 93: 560–567
  • Bäckström T, Andréen L, Birzniece V, Björn I, Johansson I M, Nordenstam-Haghjo M, Nyberg S, Sundström-Poromaa I, Wahlström G, Wang M, et al. The role of hormones and hormonal treatment in premenstrual syndrome. CNS Drugs 2003; 17: 325–342
  • Andréen L, Sundström-Poromaa I, Bixo M, Nyberg S, Bäckström T. Allopregnanolone concentration and mood – a bimodal association in postmenopausal women treated with oral progesterone. Psychopharmacology (Berl) 2006; 187: 209–221
  • Carl P, Hogskilde S, Nielsen J W, Sorensen M B, Lindholm M, Karlen B, Bäckström T. Pregnanolone emulsion. A preliminary pharmacokinetic and pharmacodynamic study of a new intravenous anaesthetic agent. Anaesthesia 1990; 45: 189–197
  • Bäckström T, Andersson A, Andréen L, Birzniece V, Bixo M, Björn I, Haage D, Isaksson M, Johansson I M, Lindblad C, et al. Pathogenesis in menstrual cycle-linked CNS disorders. Ann NY Acad Sci 2003; 1007: 42–53
  • Lee G P, Loring D W, Meador K J, Flanigin H F, Brooks B S. Severe behavioral complications following intracarotid sodium amobarbital injection: implications for hemispheric asymmetry of emotion. Neurology 1988; 38: 1233–1236
  • Cherek D R, Spiga R, Egli M. Effects of response requirement and alcohol on human aggressive responding. J Exp Anal Behav 1992; 58: 577–587
  • Dougherty D M, Cherek D R, Bennett R H. The effects of alcohol on the aggressive responding of women. J Stud Alcohol 1996; 57: 178–186
  • Beauchamp M H, Ormerod B K, Jhamandas K, Boegman R J, Beninger R. J. Neurosteroids and reward: allopregnanolone produces a conditioned place aversion in rats. Pharmacol Biochem Behav 2000; 67: 29–35
  • Masia S L, Perrine K, Westbrook L, Alper K, Devinsky O. Emotional outbursts and post-traumatic stress disorder during intracarotid amobarbital procedure. Neurology 2000; 54: 1691–1693
  • Ben-Porath D D, Taylor S P. The effects of diazepam (valium) and aggressive disposition on human aggression: an experimental investigation. Addict Behav 2002; 27: 167–177
  • Wenzel R R, Bartel T, Eggebrecht H, Philipp T, Erbel R. Central-nervous side effects of midazolam during transesophageal echocardiography. J Am Soc Echocardiogr 2002; 15: 1297–1300
  • Miczek K A, Fish E W, De Bold J F. Neurosteroids, GABAA receptors, and escalated aggressive behavior. Horm Behav 2003; 44: 242–257
  • Björn I, Bixo M, Nöjd K S, Collberg P, Nyberg S, Sundström-Poromaa I, Bäckström T. The impact of different doses of medroxyprogesterone acetate on mood symptoms in sequential hormonal therapy. Gynecol Endocrinol 2002; 16: 1–8
  • Andréen L, Bixo M, Nyberg S, Sundström-Poromaa I, Bäckström T. Progesterone effects during sequential hormone replacement therapy. Eur J Endocrinol 2003; 148: 571–577
  • Wang M, Hammarbäck S, Lindhe B A, Bäckström T. Treatment of premenstrual syndrome by spironolactone: a double-blind, placebo-controlled study. Acta Obstet Gynecol Scand 1995; 74: 803–808
  • Freeman E W, Rickels K. Characteristics of placebo responses in medical treatment of premenstrual syndrome. Am J Psychiatry 1999; 156: 1403–1408
  • Yonkers K A, Clark R H, Trevedi M H. The psychopharmacological treatment of non major mood disorders. Modern problems in pharmacopsychiatry, A J Rush. Karger, Basel 1997; 25: 146–166
  • Magos A L, Brincat M, Studd J W. Treatment of the premenstrual syndrome by subcutaneous estradiol implants and cyclical oral norethisterone: placebo controlled study. Br Med J (Clin Res Ed) 1986; 292: 1629–1633
  • Benedetti F, Amanzio M, Maggi G. Potentiation of placebo analgesia by proglumide. Lancet 1995; 346: 1231
  • Sher L. The placebo effect on mood and behavior: the role of the endogenous opioid system. Med Hypotheses 1997; 48: 347–349

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.