70
Views
3
CrossRef citations to date
0
Altmetric
Breast

Effects of pre- and postmenopausal use of exogenous hormones on receptor content in normal human breast tissue: A randomized study

, , &
Pages 475-480 | Received 20 Feb 2008, Accepted 29 May 2008, Published online: 07 Jul 2009

References

  • Colditz G A. Relationship between estrogen levels, use of hormone replacement therapy, and breast cancer. J Natl Cancer Inst 1998; 90: 814–823
  • Anderson E, Clarke R B. Steroid receptors and cell cycle in normal mammary epithelium. J Mammary Gland Biol Neoplasia 2004; 9: 3–13
  • Collaborative Group in Hormonal Factors in Breast Cancer. Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies. Lancet 1996; 347: 1713–1727
  • Lund E, Bakken K, Dumeaux V, Andersen V, Kumle M. Hormone replacement therapy and breast cancer in former users of oral contraceptives. The Norwegian Women and Cancer study. Int J Cancer 2007; 121: 645–648
  • Magnusson C, Persson R I, Baron A J, Correia N, Bergström R, Adami H-O. Breast cancer risk following long-term oestrogen and oestrogen–progestogen replacement therapy. Int J Cancer 1999; 81: 339–344
  • Bradford M M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248–254
  • Conover W J. Practical non parametric statistics. John Wiley & Sons, New York 1999
  • Altman D G. Practical statistics for medical research. Chapman & Hall, London 1991
  • Battersby S, Robertson B J, Anderson T J, King R JB, McPherson K. Influence of menstrual cycle, parity and oral contraceptive use on steroid hormone receptors in normal breast. Br J Cancer 1992; 65: 601–607
  • Eigeliene N, Härkönen P, Erkkola R. Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures. BMC Cancer 2006; 6: 246
  • Isaksson E, Sahlin L, Söderqvist G, von Schoultz E, Masironi B, Wickman M, Wilking N, von Schoultz B, Skoog L. Expression of sex steroid receptors and IGF-1 mRNA in breast tissue – effects of hormonal treatment. J Steroid Biochem Mol Biol 1999; 70: 257–262
  • Markopoulos C, Berger U, Wilson P, Gazet J-C, Coombes R C. Oestrogen receptor content of normal breast cells and breast carcinomas throughout the menstrual cycle. BMJ 1988; 296: 1349–1351
  • Cheng G, Li Y, Omoto Y, Wang Y, Berg T, Nord M, Vikho P, Warner M, Piao Y S, Gustafsson J A. Differential regulation of estrogen receptor (ER) α and ERβ in primate mammary gland. J Clin Endocrinol Metab 2005; 90: 435–444
  • Khan S A, Rogers M AM, Khurana K K, Meguid M M, Numann P J. Estrogen receptor expression in benign breast epithelium and breast cancer risk. J Natl Cancer Inst 1998; 90: 37–42
  • Söderqvist G, von Schoultz B, Tani E, Skoog L. Estrogen and progesterone receptor content in breast epithelial cells from healthy women during the menstrual cycle. Am J Obstet Gynecol 1993; 168: 874–887
  • Cline J M, Söderqvist G, von Schoultz B, Skoog L, von Schoultz E. Effects of hormone replacement therapy on the mammary gland of surgically postmenopausal macaques. Am J Obstet Gynecol 1996; 174: 93–100
  • Hofseth L J, Raafat A M, Ouch J R, Pathak D R, Slomski C A, Haslam S Z. Hormone replacement therapy with estrogen or estrogen plus medroxyprogesterone acetate is associated with increased epithelial proliferation in the normal postmenopausal breast. J Clin Endocrinol Metab 1999; 84: 4559–4565
  • Hargreaves D F, Knox F, Swindell R, Potten C S, Bundred N J. Epithelial proliferation and hormone receptor status in the normal postmenopausal breast and the effects of hormone replacement therapy. Br J Cancer 1998; 78: 945–949
  • Isaksson E, von Schoultz E, Odlind V, Söderqvist G, Csemiczky G, Carlström K, Skoog L, von Schoultz B. Effects of oral contraceptives on breast proliferation. Breast Cancer Res Treat 2001; 65: 163–169
  • Lawson J S, Field A S, Champion S, Tran D, Ishikura H, Trichopoulos D. Low oestrogen receptor α expression in normal breast tissue underlies low breast cancer incidence in Japan. Lancet 1999; 354: 1787–1788
  • Shoker B S, Jarvis C, Clarke R B, Anderson E, Hewlett J, Davies M P, Sibson D R, Sloane J P. Estrogen receptor-positive proliferating cells in the normal and precancerous breast. Am J Pathol 1999; 155: 1811–1815
  • Zeps N, Bentel J M, Papadimitriou J M, D'Antuono M F, Dawkins H J. Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth. Differentiation 1998; 62: 221–226
  • Clarke R B, Howell A, Potten C S, Anderson E. Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 1997; 57: 4987–4991
  • Clarke R B, Howell A, Anderson E. Estrogen sensitivity of normal human breast tissue in vivo and implanted into athymic nude mice: analysis of the relationship between estrogen-induced proliferation and progesterone receptor expression. Breast Cancer Res Treat 1997; 45: 121–133
  • Söderqvist G, Isaksson E, von Schoultz B, Carlström K, Tani E, Skoog L. Proliferation on breast epithelial cells in healthy women during the menstrual cycle. Am J Obstet Gynecol 1997; 176: 123–128
  • Clarke R B. Human breast cell proliferation and its relationship to steroid receptor expression. Climacteric 2004; 7: 129–137
  • Ronnov-Jessen L, Petersen O W, Bissell M J. Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol Rev 1996; 76: 69–125
  • Smith R A, Lea R A, Weinstein S R, Griffiths L R. Progesterone, glucocorticoid, but not estrogen receptor mRNA is altered in breast cancer stroma. Cancer Lett 2007; 255: 77–84
  • Krämer E A, Seeger H, Krämer B, Wallwiener D, Mueck A O. The effect of progesterone, testosterone and synthetic progestogens on growth factor and estradiol treated human cancerous and benign breast cells. Eur J Obstet Gynecol Reprod Biol 2006; 129: 77–83

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.