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Uterus

The expression of estrogen receptor isoforms alpha, beta and insulin-like growth factor-I in uterine leiomyoma

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Pages 549-554 | Received 27 Nov 2007, Accepted 27 Jun 2008, Published online: 07 Jul 2009

References

  • Ogawa S, Inoue S, Watanabe T, Orimo A, Hosoi T, Ouchi Y, Muramatsu M. Molecular cloning and characterization of human estrogen receptor βcx: a potential inhibitor of estrogen action in human. Nucleic Acids Res 1998; 26: 3505–3512
  • Enmark E, Gustafsson J-Å. Oestrogen receptors – an overview. J Intern Med 1999; 246: 133–138
  • Andersen J. Growth factors and cytokines in uterine leiomyomas. Semin Reprod Endocrinol 1996; 14: 269–282
  • Murphy L J, Murphy L C, Friesen H G. Estrogen induces insulin-like growth factor-I expression in the rat uterus. Mol Endocrinol 1987; 1: 445–450
  • Swartz C D, Afshari C A, Yu L, Hall K E, Dixon D. Estrogen-induced changes in IGF-I, Myb family and MAP kinase pathway genes in human uterine leiomyoma and normal uterine smooth muscle cell lines. Mol Hum Reprod 2005; 11: 441–450
  • Welle S, Thornton C. Insulin-like growth factor-1, actin and myosin heavy chain messenger RNAs in skeletal muscle after an injection of growth hormone in subjects over 60 years old. J Endocrinol 1997; 155: 93–97
  • Liu W, Saint D A. A new quantitative method of real time reverse transcription polymerase chain reaction assay based on simulation of polymerase chain reaction kinetics. Anal Biochem 2002; 302: 52–59
  • Barbarisi A, Petillo O, Di Lieto A, Melone M AB, Margarucci S, Cannas M, Peluso G. 17-β Estradiol elicits an autocrine leiomyoma cell proliferation: evidence for a stimulation of protein kinase-dependent pathway. J Cell Physiol 2001; 186: 414–424
  • Yamada T, Nakago S, Kurachi O, Wang J, Takekida S, Matsuo H, Maruo T. Progesterone down-regulates insulin-like growth factor-I expression in cultured human uterine leiomyoma cells. Hum Reprod 2004; 19: 815–821
  • He H, Nie H X, Moore A B, Richards R G, Dixon D. Overexpression of insulin-like growth factor 1(IGF-I) with IGF-I receptor signaling and mitogen activated protein kinase (MAPK) activation in human uterine leiomyoma. Toxicologist 2002; 1–5: 375
  • Volmat V, Camps M, Arkinstall S, Pouyssegur J, Lenormand P. The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases. J Cell Sci 2001; 114: 3433–3443
  • Umayahara Y, Kawamori R, Watada H, Imano E, Iwama N, Morishima T, Yamasaki Y, Kajimoto Y, Kamada T. Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. J Biol Chem 1994; 269: 16433–16442
  • Paech K, Webb P, Kuiper G G, Nilsson S, Gustafsson S, Gustafsson J. Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science 1997; 277: 1508–1510
  • Weihua Z, Saji S, Mäkinen S, Cheng G, Jensen E V, Warner M, Gustafsson J A. Estrogen receptor (ER) β, a modulator of ERα in the uterus. Proc Natl Acad Sci U S A 2000; 97: 5936–5941
  • Herynk M H, Fuqua S A. Estrogen receptor mutations in human disease. Endocr Rev 2004; 25: 869–898
  • Bardin A, Hoffman P, Boulle N, Katsaros D. Involvement of estrogen receptor β in ovarian carcinogenesis. Cancer Res 2004; 64: 5861–5869
  • Lazennec G, Bresson D, Lucas A, Chauveau C, Vignon F. ERβ inhibits proliferation and invasion of breast cancer cells. Endocrinology 2001; 142: 4120–4130
  • Hall J M, McDonnell D P. The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogen and antiestrogens. Endocrinology 1999; 140: 5566–5578
  • Fournier B, Gutzwiller S, Dittmar T, Matthias G, Steenbergh P, Matthias P. Estrogen receptor(ER)-α, but not ER-β, mediates regulations of the insulin-like growth factor 1 gene by antiestrogen. J Biol Chem 2001; 276: 35444–35449
  • Russell K S, Haynes M P, Sinha D, Clerisme E, Bender J R. Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. Proc Natl Acad Sci U S A 2000; 97: 5930–5935
  • Jakimiuk A J, Bogusiewicz M, Tarkowski R, Dziduch P, Adamiak A, Wróbel A, Haczyński J, Magoffin D A, Jakowicki J A. Estrogen receptor α and β expression in uterine leiomyomas from premenopausal women. Fertil Steril 2004; 82: 1244–1249
  • Wang H, Wu X, Englund K, Masironi B, Eriksson H, Sahlin L. Differential expression of estrogen receptor α and β in human myometrium and leiomyoma during the proliferative phase of the menstrual cycle and after GnRHa treatment. Gynecol Endocrinol 2001; 15: 443–452
  • Roan C J, Chuang J H, Hsu T Y, Tsai H Y, Pan L L, Cheng J T. Estrogen receptor β is not increasingly expressed in leiomyoma nodules which show no progressive enlargement in premenopausal women. J Formos Med Assoc 2005; 104: 920–925

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