Hormone therapy modulates ET_A mRNA expression in the aorta of ovariectomised New Zealand White rabbits

References

• Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E, Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 1998; 280(7)605–613
   PubMed Web of Science ®Google Scholar
• Rossouw J E, Anderson G L, Prentice R L, LaCroix A Z, Kooperberg C, Stefanick M L, Jackson R D, Beresford S A, Howard B V, Johnson K C, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 2002; 288(3)321–333
   PubMed Web of Science ®Google Scholar
• Anderson G L, Limacher M, Assaf A R, Bassford T, Beresford S A, Black H, Bonds D, Brunner R, Brzyski R, Caan B, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA 2004; 291(14)1701–1712
   PubMed Web of Science ®Google Scholar
• Clarkson T B. Progestogens and cardiovascular disease. A critical review. J Reprod Med 1999; 44(2 Suppl)180–184
   Google Scholar
• Koh K K, Sakuma I. Should progestins be blamed for the failure of hormone replacement therapy to reduce cardiovascular events in randomized controlled trials. Arterioscler Thromb Vasc Biol 2004; 24(7)1171–1179
   Google Scholar
• Schiffrin E L. Role of endothelin-1 in hypertension and vascular disease. Am J Hypertens 2001; 14(6 Pt 2)83S–89S
   Google Scholar
• Ylikorkala O, Orpana A, Puolakka J, Pyorala T, Viinikka L. Postmenopausal hormonal replacement decreases plasma levels of endothelin-1. J Clin Endocrinol Metab 1995; 80(11)3384–3387
   Google Scholar
• Webb C M, Ghatei M A, McNeill J G, Collins P. 17beta-estradiol decreases endothelin-1 levels in the coronary circulation of postmenopausal women with coronary artery disease. Circulation 2000; 102(14)1617–1622
   Google Scholar
• Saitta A, Altavilla D, Cucinotta D, Morabito N, Frisina N, Corrado F, D'Anna R, Lasco A, Squadrito G, Gaudio A, et al. Randomized, double-blind, placebo-controlled study on effects of raloxifene and hormone replacement therapy on plasma no concentrations, endothelin-1 levels, and endothelium-dependent vasodilation in postmenopausal women. Arterioscler Thromb Vasc Biol 2001; 21(9)1512–1519
   Google Scholar
• Akishita M, Ouchi Y, Miyoshi H, Orimo A, Kozaki K, Eto M, Ishikawa M, Kim S, Toba K, Orimo H. Estrogen inhibits endothelin-1 production and c-fos gene expression in rat aorta. Atherosclerosis 1996; 125(1)27–38
   PubMed Web of Science ®Google Scholar
• Tan Z, Wang T H, Yang D, Fu X D, Pan J Y. Mechanisms of 17[beta]-estradiol on the production of ET-1 in ovariectomized rats. Life Sciences 2003; 73(21)2665–2674
   Google Scholar
• Lamping K G, Nuno D W. Effects of 17 beta-estradiol on coronary microvascular responses to endothelin-1. Am J Physiol 1996; 271(3 Pt 2)H1117–H1124
   Google Scholar
• Sudhir K, Ko E, Zellner C, Wong H E, Hutchison S J, Chou T M, Chatterjee K. Physiological concentrations of estradiol attenuate endothelin 1-induced coronary vasoconstriction in vivo. Circulation 1997; 96(10)3626–3632
   Google Scholar
• Winkles J A, Alberts G F, Brogi E, Libby P. Endothelin-1 and endothelin receptor mRNA expression in normal and atherosclerotic human arteries. Biochem Biophys Res Commun 1993; 191(3)1081–1088
   Google Scholar
• Seo B, Oemar B S, Siebenmann R, von Segesser L, Luscher T F. Both ETA and ETB receptors mediate contraction to endothelin-1 in human blood vessels. Circulation 1994; 89(3)1203–1208
   Google Scholar
• de Nucci G, Thomas R, D'Orleans-Juste P, Antunes E, Walder C, Warner T D, Vane J R. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. Proc Natl Acad Sci USA 1988; 85(24)9797–9800
   Google Scholar
• Sitruk-Ware R. Progestins and cardiovascular risk markers. Steroids 2000; 65(10–11)651–658
   Google Scholar
• Haarbo J, Christiansen C. The impact of female sex hormones on secondary prevention of atherosclerosis in ovariectomized cholesterol-fed rabbits. Atherosclerosis 1996; 123(1–2)139–144
   Google Scholar
• Svensson L O, Johnson S H, Olsson S E. Plasma concentrations of medroxyprogesterone acetate, estradiol and estrone following oral administration of Klimaxil, Trisequence/Provera and Divina. A randomized, single-blind, triple cross-over bioavailability study in menopausal women. Maturitas 1994; 18(3)229–238
   Google Scholar
• Lewis L K, Elder P A, Barrell G K. An ezyme linked immunosorbent assay (ELISA) for plasma medroxyprogesterone acetate (MPA). J Steroid Biochem Molec Biol 1992; 42(2)179–183
   Google Scholar
• Alexandersen P, Haarbo J, Sandholdt I, Shalmi M, Lawaetz H, Christiansen C. Norethindrone acetate enhances the antiatherogenic effect of 17beta-estradiol: a secondary prevention study of aortic atherosclerosis in ovariectomized cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol 1998; 18(6)902–907
   Google Scholar
• Dalsgaard T, Larsen C R, Mortensen A, Larsen J J, Ottesen B. New animal model for the study of postmenopausal coronary and cerebral artery function: the Watanabe heritable hyperlipidemic rabbit fed on a diet avoiding phytoestrogens. Climacteric 2002; 5(2)178–189
   PubMedGoogle Scholar
• Mulvany M J, Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 1977; 41(1)19–26
   PubMed Web of Science ®Google Scholar
• Haarbo J. Hormone replacement therapy and cardiovascular disease: the rabbit model. Br J Obstet Gynaecol 1996; 103(Suppl 13)49–52
   Google Scholar
• Wang T H, Tan Z, Liu P Q, Lu W, Yang D, Pan J Y. [Down-regulation of ETA receptor of vascular smooth muscle cells by 17 beta-estradiol]. Sheng Li Xue Bao (Acta Physiologica Sinica) 2001; 53(5)380–384
   Google Scholar
• Telemaque-Potts S, Kuc R E, Maguire J J, Ohlstein E, Yanagisawa M, Davenport A P. Elevated systemic levels of endothelin-1 and blood pressure correlate with blunted constrictor responses and downregulation of endothelin(A), but not endothelin(B), receptors in an animal model of hypertension. Clin Sci (Lond) 2002; 103(Suppl 48)357S–362S
   Google Scholar
• Pedersen N G, Pedersen S H, Dalsgaard T, Lund C O, Nilas L, Ottesen B. Progestins used in hormonal replacement therapy display different effects in coronary arteries from New Zealand white rabbits. Maturitas 2004; 49(4)304–314
   Google Scholar
• Pedersen S H, Pedersen N G, Dalsgaard T, Lund C O, Nilas L, Ottesen B. Different cerebrovascular effects of medroxyprogesterone acetate and norethisterone acetate in the New Zealand White rabbit. Climacteric 2004; 7(1)12–22
   PubMed Web of Science ®Google Scholar
• Pedersen S H, Nielsen L B, Mortensen A, Sheykhzade M, Nilas L, Ottesen B. Medroxyprogesterone acetate attenuates long-term effects of 17beta-estradiol in coronary arteries from hyperlipidemic rabbits. Steroids 2006; 71(9)834–842
   Google Scholar
• Pedersen S H, Nielsen L B, Mortensen A, Nilas L, Ottesen B. Progestins oppose the effects of estradiol on the endothelin-1 receptor type B in coronary arteries from ovariectomized hyperlipidemic rabbits. Menopause – J North Am Menopause Soc 2008; 15(3)503–510
   Google Scholar
• David F L, Montezano A C, Reboucas N A, Nigro D, Fortes Z B, Carvalho M H, Tostes R C. Gender differences in vascular expression of endothelin and ET(A)/ET(B) receptors, but not in calcium handling mechanisms, in deoxycorticosterone acetate-salt hypertension. Braz J Med Biol Res 2002; 35(9)1061–1068
   Google Scholar
• David F L, Carvalho M H, Cobra A L, Nigro D, Fortes Z B, Reboucas N A, Tostes R C. Ovarian hormones modulate endothelin-1 vascular reactivity and mRNA expression in DOCA-salt hypertensive rats. Hypertension 2001; 38(3 Pt 2)692–696
   Google Scholar
• Akishita M, Kozaki K, Eto M, Yoshizumi M, Ishikawa M, Toba K, Orimo H, Ouchi Y. Estrogen attenuates endothelin-1 production by bovine endothelial cells via estrogen receptor. Biochem Biophys Res Commun 1998; 251(1)17–21
   Google Scholar
• Rodrigo M C, Martin D S, Eyster K M. Vascular ECE-1 mRNA expression decreases in response to estrogens. Life Sci 2003; 73(23)2973–2983
   Google Scholar
• Gray G A, Mickley E J, Webb D J, McEwan P E. Localization and function of ET-1 and ET receptors in small arteries post-myocardial infarction: upregulation of smooth muscle ET(B) receptors that modulate contraction. Br J Pharmacol 2000; 130(8)1735–1744
   Google Scholar
• Hong H J, Liu J C, Chan P, Juan S H, Loh S H, Lin J G, Cheng T H. 17beta-estradiol downregulates angiotensin-II-induced endothelin-1 gene expression in rat aortic smooth muscle cells. J Biomed Sci 2004; 11(1)27–36
   Google Scholar
• Smith P JW, Ornatsky O, Stewart D J, Picard P, Dawood F, Wen W H, Liu P P, Webb D J, Monge J C. Effects of estrogen replacement on infarct size, cardiac remodeling, and the endothelin system after myocardial infarction in ovariectomized rats. Circulation 2000; 102(24)2983–2989
   Google Scholar
• Vikman P, Edvinsson L. Gene expression profiling in the human middle cerebral artery after cerebral ischemia. Eur J Neurol 2006; 13(12)1324–1332
   Google Scholar
• David F L, Carvalho M H, Cobra A L, Nigro D, Fortes Z B, Reboucas N A, Tostes R C. Ovarian hormones modulate endothelin-1 vascular reactivity and mRNA expression in DOCA-salt hypertensive rats. Hypertension 2001; 38(3 Pt 2)692–696
   Google Scholar
• Hansen V B, Skajaa K, Aalkjaer C, Oxlund H, Glavind E B, Petersen O B, Forman A. The effect of oophorectomy on mechanical properties of rabbit cerebral and coronary isolated small arteries. Am J Obstet Gynecol 1996; 175(5)1272–1280
   Google Scholar