Genetic risk for white matter abnormalities in bipolar disorder

References

• Adler CM, Holland SK, Schmithorst V, Wilke M, Weiss KL, Pan H, et al. Abnormal frontal white matter tracts in bipolar disorder: A diffusion tensor imaging study. Bipolar Disorders 2004; 6: 197–203
   PubMed Web of Science ®Google Scholar
• Ahearn EP, Speer MC, Chen YT, Steffens DC, Cassidy F, Van Meter S, Provenzale JM, Weisler RH, Krishnan KR. Investigation of Notch3 as a candidate gene for bipolar disorder using brain hyperintensities as an endophenotype. American Journal of Medical Genetics 2002; 114: 652–658
   PubMedGoogle Scholar
• Angst J. The emerging epidemiology of hypomania and bipolar II disorder. Journal of Affective Disorders 1998; 50: 143–151
   PubMed Web of Science ®Google Scholar
• Bao J, Wolpowitz D, Role LW, Talmage DA. Back signaling by the Nrg-1 intracellular domain 2003; 1133–1141
   Google Scholar
• Bengtsson SL, Nagy Z, Skare S, Forsman L, Forssberg H, Ullen F. Extensive piano practicing has regionally specific effects on white matter development. Natural Neuroscience 2005; 8: 1148–1150
   PubMed Web of Science ®Google Scholar
• Beyer JL, Taylor WD, MacFall JR, Kuchibhatla M, Payne ME, Provenzale JM, Cassidy F, Krishnan KRR. Cortical white matter microstructural abnormalities in bipolar disorder. Neuropsychopharmacology 2005; 30: 2225–2229
   PubMed Web of Science ®Google Scholar
• Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks CA, Harris BC, et al. A functional magnetic resonance imaging study of bipolar disorder - State- and trait-related dysfunction in ventral prefrontal cortices. Archives of General Psychiatry 2003; 60: 601–609
   PubMed Web of Science ®Google Scholar
• Brambilla P, Nicoletti M, Sassi R. B, Mallinger A. G, Frank E, Keshavan MS, et al. Corpus callosum signal intensity in patients with bipolar and unipolar disorder. 2004; 221–225
   Google Scholar
• Canoll PD, Musacchio JM, Hardy R, Reynolds R, Marchionni MA, Salzer JL. GGF/Neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors. Neuron 1996; 17: 229–243
   PubMed Web of Science ®Google Scholar
• Corfas G, Rosen KM, Aratake H, Krauss R, Fischbach GD. Differential expression of ARIA isoforms in the rat brain. Neuron 1995; 14: 103–115
   PubMed Web of Science ®Google Scholar
• Fernandez P-A, Tang DG, Cheng L, Prochiantz A, Mudge AW, Raff MC. Evidence that axon-derived neuregulin promotes oligodendrocyte survival in the developing rat optic nerve. Neuron 2000; 28: 81–90
   PubMedGoogle Scholar
• Fields RD. White matter in learning, cognition and psychiatric disorders. Trends in Neurosciences 2008; 31: 361–370
   PubMed Web of Science ®Google Scholar
• Georgieva L, Dimitrova A, Ivanov D, Nikolov I, Williams NM, Grozeva D, et al. Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia. Biological Psychiatry 2006; 64(5)419–427
   Google Scholar
• Gilad Silberberg ADRP-KRN. The involvement of ErbB4 with schizophrenia:. Association and Expression Studies. American Journal of Human Genetics Part B: Neuropsychiatric Genetics 2006; 40: 712–718
   Google Scholar
• Green EK, Raybould R, MacGregor S, Gordon-Smith K, Heron J, Hyde S, et al. Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Archives of General Psychiatry 2005; 62: 642–648
   PubMed Web of Science ®Google Scholar
• Hall J, Whalley HC, Job DE, Baig BJ, McIntosh AM, Evans KL, et al. A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms. Nature Neuroscience 2006; 9: 1477–1478
   PubMed Web of Science ®Google Scholar
• Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence. Molecular Psychiatry 2005; 10: 804–804
   Google Scholar
• Haznedar MM, Roversi F, Pallanti S, Baldini-Rossi N, Schnur DB, LiCalzi EM, et al. Fronto-thalamo-striatal gray and white matter volumes and anisotropy of their connections in bipolar spectrum illnesses. Biological Psychiatry 2005; 57: 733–742
   PubMed Web of Science ®Google Scholar
• Houenou J, Wessa M, Douaud G, Leboyer M, Chanraud S, Perrin M, et al. Increased white matter connectivity in euthymic bipolar patients: Diffusion tensor tractography between the subgenual cingulate and the amygdalo-hippocampal complex. Molecular Psychiatry 2007; 12: 1001–1010
   PubMed Web of Science ®Google Scholar
• Iwamoto K, Kakiuchi C, Bundo M, Ikeda K, Kato T. Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders. Molecular Psychiatry 2004; 9: 406–416
   PubMed Web of Science ®Google Scholar
• Joffe RT, Lippert GP, Gray TA, Sawa G, Horvath Z. Mood disorder and multiple sclerosis. Archives of Neurology 1987; 44(4)376–378
   PubMedGoogle Scholar
• Konrad A, Vucurevic G, Stoeter P, Dahmen N, Musso F, Winterer G. ERBB4 genotype effects on human brain structure. Schizophrenia Research 2008; 98: 128–128
   Google Scholar
• Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, et al. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease. Proceedings of the National Academy of Sciences of the United States of America 2006; 103: 6747–6752
   PubMed Web of Science ®Google Scholar
• Law AJ, Shannon Weickert C, Hyde TM, Kleinman JE, Harrison PJ. Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain. Neuroscience 2004; 127: 125–136
   PubMedGoogle Scholar
• Lopez-Bendito G, Cautinat A, Sanchez JA, Bielle F, Flames N, Garratt AN, et al. Tangential neuronal migration controls axon guidance: A role for neuregulin-1 in thalamocortical axon navigation. Cell 2006; 125: 127–42
   PubMed Web of Science ®Google Scholar
• McDonald C, Bullmore ET, Sham PC, Chitnis X, Wickham H, Bramon E, et al. Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. Archives of General Psychiatry 2004; 61: 974–984
   PubMed Web of Science ®Google Scholar
• McIntosh AM, Job D, Moorhead TWJ, Harrison LK, Whalley HC, et al. Genetic liability to schizophrenia or bipolar disorder and its relationship to brain structure. American Journal of Medical Genetics 2006; 141B: 76–83
   PubMedGoogle Scholar
• McIntosh AM, Job DE, Moorhead TW, Harrison LK, Lawrie SM, Johnstone EC. White matter density in patients with schizophrenia, bipolar disorder and their unaffected relatives. Biological Psychiatry 2005; 58: 254–257
   PubMed Web of Science ®Google Scholar
• McIntosh AM, Whalley HC, McKirdy J, Hall J, Sussmann JE, Johnstone EC, et al. Prefrontal function and activation in bipolar disorder and schizophrenia. American Journal of Psychiatry 2008; 165: 378–384
   PubMed Web of Science ®Google Scholar
• Mechelli A, Prata DP, Fu CHY, Picchioni M, Kane F, Kalidindi S, et al. The effects of neuregulin1 on brain function in controls and patients with schizophrenia and bipolar disorder. NeuroImage, In Press, Corrected Proof
   Google Scholar
• Mei L, Xiong W-C. Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. National Review of Neuroscience 2008; 9: 437–452
   PubMed Web of Science ®Google Scholar
• Michailov GV, Sereda MW, Brinkmann BG, Fischer TM, Haug B, Birchmeier C, et al. Axonal Neuroimage 2004; 42(2)817–826
   Google Scholar
• Norton N, Moskvina V, Morris DW, Bray NJ, Zammit S, Williams NM, Williams HJ, Preece AC, Dwyer S, Wilkinson JC, Spurlock G, Kirov G, Buckland P, Waddington JL, Gill M, Corvin AP, Owen MJ, O'Donovan MC. Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 141B(1)96–101
   PubMedGoogle Scholar
• Rajkowska G, Halaris A, Selemon LD. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biological Psychiatry 2001; 49: 741–752
   PubMed Web of Science ®Google Scholar
• Regenold WT, Phatak P, Marano CM, Gearhart L, Viens CH, Hisley KC. Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depression. Psychiatry Research 2007; 151: 179–188
   PubMed Web of Science ®Google Scholar
• Rio C, Rieff HI, Qi P, Corfas G. Neuregulin and erbB receptors play a critical role in neuronal migration. Neuron 1997; 19: 39–50
   PubMed Web of Science ®Google Scholar
• Ryan MM, Lockstone HE, Huffaker SJ, Wayland MT, Webster MJ, Bahn S. Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes. Molecular Psychiatry 2006; 11: 965–978
   PubMedGoogle Scholar
• Shao L, Vawter MP. Shared gene expression alterations in schizophrenia and bipolar disorder. Biological Psychiatry 2008; 64: 89–97
   PubMed Web of Science ®Google Scholar
• Stefansson H, Sigurdsson E, Steinthorsdottir V, Bjornsdottir S, Sigmundsson T, Brynjolfsson J, et al. Neuregulin 1 and susceptibility to schizophrenia. American Journal of Human Genetics 2002; 71: 185–185
   Google Scholar
• Strakowski SM, Adler CM, Holland SK, Mills N, DelBello MP. A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder. Neuropsychopharmacology 2004a; 29: 1734–40
   PubMed Web of Science ®Google Scholar
• Strakowski SM, DelBello MP, Adler CM. The functional neuroanatomy of bipolar disorder: A review of neuroimaging findings. Molecular Psychiatry 2004b; 10: 105–116
   Google Scholar
• Sussman CR, Vartanian T, Miller RH. The ErbB4 neuregulin receptor mediates suppression of oligodendrocyte maturation. Journal of Neuroscience 2005; 24(5)5757–5762
   Google Scholar
• Sussmann JE, Lymer GKS, McKirdy J, Moorhead TWJ, Maniega SM, Job D, et al. White matter abnormalities in bipolar disorder detected using diffusion tensor magnetic resonance imaging. Bipolar Disorders 2007; 9: 504–512
   PubMedGoogle Scholar
• Tan W, Wang Y, Gold B, Chen J, Dean M, Harrison PJ, et al. Molecular cloning of a brain-specific, developmentally regulated Neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia. Journal of Biological Chemistry 2007; 282(33)24343–24351
   PubMedGoogle Scholar
• Taveggia C, Zanazzi G, Petrylak A, Yano H, Rosenbluth J, Einheber S, et al. Neuregulin-1 Type III Determines the Ensheathment Fate of Axons. Neuron 2005; 47: 681–694
   PubMed Web of Science ®Google Scholar
• Thomson PA, Christoforou A, Morris SW, Adie E, Pickard BS, Porteous DJ, et al. Association of Neuregulin 1 with schizophrenia and bipolar disorder in a second cohort from the Scottish population. Molecular Psychiatry 2007; 12: 94–104
   PubMedGoogle Scholar
• Tkachev D, Mimmack ML, Ryan MM, Wayland M, Freeman T, Jones PB, et al. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder [comment]. Lancet 2003; 362: 798–805
   PubMed Web of Science ®Google Scholar
• Vartanian T, Fischbach G, Miller R. Failure of spinal cord oligodendrocyte development in mice lacking neuregulin. Proceedings of the National Academy of Sciences of the USA 1999; 731–735
   PubMedGoogle Scholar
• Videbech P. MRI findings in patients with affective disorder: A meta-analysis. Acta Psychiatrica Scandinavica 1997; 96: 157–168
   PubMed Web of Science ®Google Scholar
• Winterer G, Konrad A, Vucurevic G, Musso F, Stoeter P, Dahmen N. Association of 5′ end neuregulin-1 (NRG1) gene variation with subcortical medial frontal microstructure in humans. NeuroImage 2008; 40: 712–718
   PubMedGoogle Scholar
• Wobrock T, Kamer T, Roy A, Vogeley K, Schneider-Axmann T, Wagner M, et al. Reduction of the internal capsule in families affected with schizophrenia. Biological Psychiatry 2008; 63: 65–71
   PubMedGoogle Scholar