296
Views
12
CrossRef citations to date
0
Altmetric
Original

Valproate and neuroprotective effects for bipolar disorder

, MD
Pages 410-413 | Published online: 16 Sep 2009

References

  • Asghari V, Wang JF, Reiach JS, Young LT. Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY-5Y cells. Molecular Brain Research 1999; 58: 95–102
  • Atmaca M, Yildirim H, Ozdemir H, Ogur E, Tezcan E. Hippocampal 1H MRS in patients with bipolar disorder taking valproate versus valproate plus quetiapine. Psychological Medicine 2007; 37: 121–129
  • Atmaca M, Ozdemir H, Cetinkaya S, Parmaksiz S, Belli H, Poyraz K, et al. Cingulate gyrus volumetry in drug free bipolar patients and patients treated with valproate or valproate and quetiapine. Journal of Psychiatric Research 2007; 41: 821–827
  • Baxter LR, Schwartz JM, Phelps ME, Mazziotta JC, Guze BH, Selin CE, et al. Reduction of prefrontal cortex glucose metabolism common to three types of depression. Archives of General Psychiatry 1989; 46: 243–250
  • Bertolino A, Frye M, Callicott JH, Mattay VS, Rakow R, Shelton-Repella J, et al. Neuronal pathology in the hippocampal area of patients with bipolar disorder: A study with proton magnetic resonance spectroscopic imaging. Biological Psychiatry 2003; 53: 906–913
  • Bowden CL. Dosing strategies and time course of response to antimanic drugs. Journal of Clinical Psychiatry 1996; 57(Suppl.13)4–9
  • Bown CD, Wang JF, Chen B, Young LT. Regulation of ER stress proteins by valproate: Therapeutic implications. Bipolar Disorders 2002; 4: 145–151
  • Bown CD, Wang JF, Chen B, Young LT. Regulation of ER stress proteins by valproate: Therapeutic implications. Bipolar Disorders 2002; 4: 145–151
  • Cendes F, Andermann F, Dubeau F, Matthews PM, Arnold DL. Normalization of neuronal metabolic dysfunction after surgery for temporal lobe epilepsy. Evidence from proton MR spectroscopic imaging. Neurology 1997; 49: 1525–1533
  • Chang KD, Adleman N, Dienes K, Barnea-Goraly N, Reiss A, Ketter T. Decreased N-acetylaspartate in children with familial bipolar disorder. Biological Psychiatry 2003; 53: 1059–1065
  • Chen G, Hasanat KA, Bebchuk JM, Moore GJ, Glitz D, Manji HK. Regulation of signal transduction pathways and gene expression by mood stabilizers and antidepressants. Psychosomatic Medicine 1999; 61: 599–617
  • Chen G, Zeng WZ, Yuan PX, Huang LD, Jiang YM, Zhao ZH, et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. Journal of Neurochemistry 1999; 72: 879–882
  • Chuang DM. The antiapoptotic actions of mood stabilizers: Molecular mechanisms and therapeutic potentials. Annals of the NewYork Academy of Science 2005; 1053: 195–204
  • Cui J, Shao L, Young LT, Wang JF. Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate. Neuroscience 2007; 144: 1447–1453
  • Dando TM, Keating GM. Quetiapine: A review of its use in acute mania and depression associated with bipolar disorder. Drugs 2005; 65: 2533–2551
  • De Sarno P, Li X, Jope RS. Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium. Neuropharmacology 2002; 43: 1158–1164
  • Deicken RF, Pegues MP, Anzalone S, Feiwell R, Soher B. Lower concentration of hippocampal N-acetylaspartate in familial bipolar I disorder. American Journal of Psychiatry 2003; 160: 873–882
  • Drevets WC. Prefrontal cortical-amygdalar metabolism in major depression. Annals of New York Academy of Science 1999; 877: 614–637
  • Drevets WC. Neuroimaging studies of mood disorders. Biological Psychiatry 2000; 48: 813–829
  • Dringen R, Hirrlinger J. Glutathione pathways in the brain. Biological Chemistry 2003; 384: 505–516
  • Fukumoto T, Morinobu S, Okamoto Y, Kagay A, Yamawaki S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology 2001; 158: 100–106
  • Gao K, Calabrese JR. Newer treatment studies for bipolar depression. Bipolar Disord 2005; 7: 13–23
  • Gottlicher M, Minucc S, Zhu P, Kramer OH, Schimpf A, Giavara S, et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO Journal 2001; 20: 6969–6978
  • Hamakawa H, Kato T, Shioiri T, Inubushi T, Kato N. Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder. Psychological Medicine 1999; 29: 639–644
  • Hao Y, Creson T, Zhang L, Li P, Du F, Yuan P, et al. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. Journal of Neuroscience 2004; 24: 6590–6599
  • Hiroi T, Wei H, Hough C, Leeds P, Chuang D-M. Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: Roles of intracellular calcium, GRP78 and Bcl-2. Pharmacogenomics Journal 2005; 5: 102–111
  • Hyman SE, Nestler EJ. Initiation and adaptation: A paradigm for understanding psychotropic drug action. American Journal of Psychiatry 1996; 153: 151–162
  • Jenkins BG, Klivenyi P, Kustermann E, Andreassen OA, Ferrante RJ, Rosen BR, et al. Non-linear decrease over time in N-acetylaspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice. Journal of Neurochemistry 2000; 74: 2108–2119
  • Kanai H, Sawa A, Chen RW, Leeds P, Chuang DM. Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons. Pharmacogenomics Journal 2004; 4: 336–344
  • Lenox RH, Mcnamara RK, Papke RL, Manji HK. Neurobiology of lithium: An update. Journal of Clinical Psychiatry 1998; 59(Suppl.6)S37–47
  • Manji HK, Potter WZ, Lenox RH. Signal transduction pathways: Molecular targets for lithium's action. Archives of General Psychiatry 1995; 52: 531–543
  • McElroy SL, Keck Jr PE, Pope Jr HG, Hudson JI. Valproate in the treatment of bipolar disorder: Literature review and clinical guidelines. Journal of Clinical Psychopharmacology 1992; 12(Suppl.)S42–51
  • McIntyre RS, Brecher M, Paulsson B, Huizar K, Mullen J. Quetiapine or haloperidol as monotherapy for bipolar mania: A 12-week, double-blind, randomised, parallel-group, placebo-controlled trial. European Neuropsychopharmacology 2005; 15: 573–585
  • Moffett JR, Namboodiri MA. Differential distribution of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat forebrain. Journal of Neurocytology 1995; 24: 409–433
  • Moore GJ, Bebchuk JM, Hasanat K, Chen G, Seraji-Bozorgzad N, Wilds IB, et al. Lithium increases N-acetyl-aspartate in the human brain: In vivo evidence in support of Bcl-2's neurotrophic effects?. Biological Psychiatry 2000; 48: 1–8
  • Ozaki N, Chuang DM. Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain. Journal of Neurochemistry 1997; 69: 2336–2344
  • Petroff OA, Errante LD, Rothman DL, Kim JH, Spencer DD. Neuronal and glial metabolite content of the epileptogenic human hippocampus. Annals of Neurology 2002; 52: 635–642
  • Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. Journal of Biologcal Chemistry 2001; 276: 36734–36741
  • Post RM. Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. American Journal of Psychiatry 1992; 149: 999–1010
  • Rajkowska G, Halaris D, Selemon LD. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biological Psychiatry 2001; 49: 741–752
  • Ren M, Leng Y, Jeong M, Leeds PR, Chuang DM. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: Potential roles of histone deacetylase inhibition and heat shock protein induction. Journal of Neurochemistry 2004; 89: 1358–1367
  • Richards TL. Proton MR spectroscopy in multiple sclerosis: Value in establishing diagnosis, monitoring progression and evaluating therapy. American Journal of Radiolog 1991; 157: 1073–1078
  • Urenjak J, Williams SR, Gadian DG, Noble M. Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. Journal of Neuroscience 1993; 13: 981–989
  • Wang JF, Bown C, Young LT. Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78. Molecular Pharmacology 1999; 55: 521–527
  • Winsberg ME, Sachs N, Tate DL, Adalsteinsson E, Spielman D, Ketter TA. Decreased dorsolateral prefrontal N-acetylaspartate in bipolar disorder. Biological Psychiatry 2000; 47: 475–481
  • Yuan PX, Huang LD, Jiang YM, Gutkind JS, Manji HK, Chen G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. Journal of Biological Chemistry 2001; 276: 31674–31683

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.