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Psoriasis

Methotrexate versus hydroxycarbamide (hydroxyurea) as a weekly dose to treat moderate‐to‐severe chronic plaque psoriasis: A comparative study

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Pages 295-300 | Received 10 Mar 2007, Accepted 02 Jun 2007, Published online: 12 Jul 2009

References

  • Green M. S., Prystowsky J. H., Cohen S. R., Cohen J. I., Lebwohl M. G. Infectious complications of erythrodermic psoriasis. J Am Acad Dermatol 1996; 34: 911–14
  • Leavell U. W., Mersack I. P., Smith C. Survey of the treatment of psoriasis with hydroxyurea. Arch Dermatol 1973; 107: 467
  • Fredriksson T., Pettersson U. Severe psoriasis – oral therapy with a new retinoid. Dermatologica 1978; 157: 238–44
  • Weinstein G. D., Frost P. Methotrexate for psoriasis: A new therapeutic schedule. Arch Dermatol 1971; 103: 33–8
  • Heydendael V. M. R., Spuls P. I., Opmeer B. C., de Borgie C. A. J. M., Reitsma J. B., Goldschmidt W. F. M., et al. Methotrexate versus cyclosporine in moderate to severe chronic plaque psoriasis. N Engl J Med 2003; 349: 658–65
  • Sharma V. K., Dutta B., Ramam M. Hydroxyurea as an alternative therapy for psoriasis. Indian J Dermatol Venereol Leprol 2004; 70: 13–17
  • Van Dooren‐Greebe R. J., Kuijpers A. L. A., Mulder J., Boo T. D., van de Kerkhof P. C. M. Methotrexate revisited: Effects of long‐term treatment in psoriasis. Br J Dermatol 1994; 130: 204–10
  • Layton A. M., Sheehan‐Dare R. A., Goodfield M. J. D., Cotterill J. A. Hydroxyurea in the management of therapy resistant psoriasis. Br J Dermatol 1989; 121: 647–53
  • Moschella S. L., Greenwald M. A. Psoriasis with hydroxyurea: An 18‐month study of 60 patients. Arch Dermatol 1973; 107: 363–8
  • Haustein U. F., Rytter M. Methotrexate in psoriasis: 26 years experience with low dose long‐term treatment. J Eur Acad Dermatol Venereol 2000; 14: 382–8
  • Kumar B., Saraswat A., Kaur I. Short‐term methotrexate therapy in psoriasis: A study of 197 patients. Int J Dermatol 2002; 41: 444–8
  • Collins P., Rogers S. The efficacy of methotrexate in psoriasis: A review of 40 cases. Clin Exp Dermatol 1992; 17: 257–60
  • Lim J. T., Tham S. N. Methotrexate in the treatment of psoriasis at the National Skin Center, Singapore. Ann Acad Med Singapore 1994; 23: 848–51
  • Sandhu K., Kaur I., Kumar B., Saraswat A. Efficacy and safety of cyclosporine versus methotrexate in severe psoriasis: A study from north India. J Dermatol 2003; 30: 458–63
  • Yarbo J. W. Hydroxyurea in the treatments of refractory psoriasis. Lancet 1969; ii: 846–7
  • Boyd A. S., Neldner K. H. Hydroxyurea therapy. J Am Acad Dermatol 1991; 25: 518–24
  • Stein K. M., Shelly W. B., Winberg R. A. Hydroxyurea in the treatment of pustular psoriasis. Br J Dermatol 1971; 85: 81–5
  • Smith C. H. Use of hydroxyurea in psoriasis. Clin Exp Dermatol 1999; 24: 2–6
  • Hattel T., Søndergaard J. Pustulosis palmaris et plantaris treated with hydroxyurea. Acta Derm Venereol 1974; 54: 152–4
  • Kumar B., Saraswat A., Kaur I. Rediscovering hydroxyurea: Its role in recalcitrant psoriasis. Int J Dermatol 2001; 40: 530–4
  • Duhra P. Treatment of gastrointestinal symptoms associated with methotrexate therapy for psoriasis. J Am Acad Dermatol 1993; 28: 466–9
  • Kumar B., Saraswat A., Kaur I. Mucocutaneous adverse effects of hydroxyurea: A prospective study of 30 psoriasis patients. Clin Exp Dermatol 2002; 27: 8–13

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