329
Views
15
CrossRef citations to date
0
Altmetric
Therapy

Patient‐reported outcomes from a multicenter, randomized, vehicle‐controlled clinical study of MAS063DP (Atopiclair) in the management of mild‐to‐moderate atopic dermatitis in adults

, , , , , , , , & show all
Pages 327-332 | Received 15 May 2008, Accepted 25 May 2008, Published online: 12 Jul 2009

References

  • Su J. C., Kemp A. S., Varigos G. A., Nolan T. M. Atopic eczema: Its impact on the family and financial cost. Arch Dis Child 1997; 76: 159–62
  • Drake L., Prendergast M., Maher R., Breneman D., Korman N., Satoi Y., et al. The impact of tacrolimus ointment on health‐related quality of life of adult and pediatric patients with atopic dermatitis. J Am Acad Dermatol 2001; 44((1 suppl):)s65–72
  • Holm E. A., Esmann S., Jemec G. B. The handicap caused by atopic dermatitis – sick leave and job avoidance. J Eur Acad Dermatol Venereol 2006; 20: 255–9
  • Abramovits W. Atopic dermatitis. J Am Acad Dermatol 2005; 53((1 suppl 1))s86–93
  • Abramovits W. Atopic dermatitis. J Am Acad Dermatol 2005; 53((1 suppl 1))s70–7
  • Tofte S. J., Hanifin J. M. Current management and therapy of atopic dermatitis. J Am Acad Dermatol 2001; 44((1 suppl 1))s13–16
  • Boguniewicz M., Nicol N. Conventional therapy for atopic dermatitis. Immunol Allergy Clin North Am 2002; 22: 107–24
  • Ellis C., Luger T., Abeck D., Allen R., Graham‐Brown R. A., De Prost Y., et al. International Consensus Conference on Atopic Dermatitis II (ICCAD II): Clinical update and current treatment strategies. Br J Dermatol 2003; 148((suppl 63))s3–10
  • Hanifin J. M., Cooper K. D., Ho V. C., Kang S., Krafchik B. R., Margolis D. J., et al. Guidelines of care for atopic dermatitis. J Am Acad Dermatol 2004; 50: 391–404
  • Hengge U. R., Ruzicka T., Schwartz R. A., Cork M. J. Adverse effects of topical glucocorticosteroids. J Am Acad Dermatol 2006; 54: 1–15
  • Fleischer A. Treatment of atopic dermatitis: Role of tacrolimus ointment as a topical noncorticosteroidal therapy. J Allergy Clin Immunol 1999; 104((3 part 3))s126–30
  • Qureshi A. A., Fischer M. A. Topical calcineurin inhibitors for atopic dermatitis: Balancing clinical benefit and possible risks. Arch Dermatol 2006; 142: 633–57
  • Abramovits W., Gover M. D., Gupta A. K. Atopiclair nonsteroidal cream. Skinmed 2005; 4: 369
  • Amagaya S., Sugishita E., Ogihara Y., Ogawa S., Okada K., Aizawa T. Comparative studies of the stereoisomers of glycyrrhetinic acid on anti‐inflammatory activities. J Pharmacobiodyn 1984; 7: 923–8
  • Bombardelli E., Curri S. B., Della Loggia R., Del Negor P., Tubaro A., Gariboldi P. Anti‐inflammatory activity of 18‐β‐glycyrrhetinic acid in Phytosome® form. Fitoterapia 1989; 60((suppl 1))s29–39
  • Monder C., White P. C. 11‐beta‐hydroxysteroid dehydrogenase. Vitam Horm 1993; 47: 187–271
  • MacKenzie M. A., Hoefnagels W. H., Jansen R. W., Benraad T. J., Kloppenborg P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. J Clin Endocrinol Metab 1990; 70: 1637–43
  • Teelucksingh S., Mackie A. D., Burt D., McIntyre M. A., Brett L., Edwards C. R. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. Lancet 1990; 335: 1060–3
  • Kroes B. H., Beukelman C. J., van den Berg A. J., Wolbink G. J., van Dijk H., Labadie R. P. Inhibition of human complement by beta‐glycyrrhetinic acid. Immunology 1997; 90: 115–20
  • Shin Y. W., Bae E. A., Lee B., Kim J. A., Kim Y. S. In vitro and in vivo antiallergic effects of Glycyrrhiza glabra and its components. Planta Med 2007; 73: 257–61
  • Lee Y. M., Hirota S., Jippo‐Kanemoto T., Kim H. R., Shin T. Y., Yeom Y., et al. Inhibition of histamine synthesis by glycyrrhetinic acid in mast cells cocultured with Swiss 3T3 fibroblasts. Int Arch Allergy Immunol 1996; 110: 272–7
  • Kang O. H., Kim J. A., Choi Y. A., Park H. J., Kim D. K., An Y. H., et al. Inhibition of interleukin‐8 production in the human colonic epithelial cell line HT‐29 by 18 beta‐glycyrrhetinic acid. Int J Mol Med 2005; 15: 981–5
  • Homma M., Minami M., Taniguchi C., Oka K., Morita S., Niitsuma T., et al. Inhibitory effects of lignans and flavonoids in saiboku‐to, a herbal medicine for bronchial asthma, on the release of leukotrienes from human polymorphonuclear leukocytes. Planta Med 2000; 66: 88–91
  • Maffei Facino R., Carini M., Aldini G., Bombardelli E., Morazzoni P., Morelli R. Free radicals scavenging action and anti‐enzyme activities of procyanidines from Vitis vinifera. A mechanism for their capillary protective action. Arzneimittelforschung 1994; 44: 592–601
  • Weindl G., Schaller M., Schäfer‐Korting M., Korting H. C. Hyaluronic acid in the treatment and prevention of skin diseases: Molecular biological, pharmaceutical and clinical aspects. Skin Pharmacol Physiol 2004; 17: 207–13
  • Grassi L., Moretti M., Bisetti A. Un nuovo farmaco mucoattivo con attivita' anti‐proteasica: la Telmesteina. Riv Ital Biol Med 1992; 12: 67–74
  • Data on file Sinclair Pharmaceuticals Ltd, Goldalming, United Kingdom, March 2005
  • Abramovits W., Boguniewicz M. A multicenter, randomized, vehicle‐controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults. J Drugs Dermatol 2006; 5: 236–44
  • Hanifin J. M., Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol. 1980, suppl 92: 44–7
  • Rajka G., Langeland T. Grading of the severity of atopic dermatitis. Acta Derm Venereol Suppl (Stockh) 1989; 144: 13–14
  • Wahlgren C. F. Itch and atopic dermatitis: An overview. J Dermatol 1999; 26: 770–9
  • Abeck D., Strom K. Optimal management of atopic dermatitis. Am J Clin Dermatol 2000; 1: 41–6
  • Kang S., Lucky A. W., Pariser D., Lawrence I., Hanifin J. M. Long‐term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. J Am Acad Dermatol 2001; 44: 58–64
  • Zuberbier T., Orlow S. J., Paller A. S., Taïeb A., Allen R., Hernanz‐Hermosa J. M., et al. Patient perspectives on the management of atopic dermatitis. J Allergy Clin Immunol 2006; 118: 226–32
  • Charman C. R., Morris A. D., Williams H. C. Topical corticosteroid phobia in patients with atopic eczema. Br J Dermatol 2000; 142: 931–6
  • Schiffner R., Schiffner‐Rohe J., Landthaler M., Stolz W. How large is the loss of effectiveness of a treatment modality between ‘theory’ and ‘practice’? An evaluation of health economics factors in a study of 1281 patients treated with ambulatory balneophototherapy. Hautarzt 2002; 53: 22–9
  • Fischer G. Compliance problems in paediatric atopic eczema. Australas J Dermatol 1996; 37: 10–13

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.