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Journal of Dermatological Treatment Volume 34, 2023 - Issue 1
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Brief Report

Upadacitinib for the treatment of concomitant psoriasis and atopic dermatitis: a case series

Luigi Gargiuloa Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy;b Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, MI, ItalyView further author information
,
Luciano Ibbaa Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy;b Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, MI, ItalyCorrespondence[email protected]
View further author information
,
Giulia Paviaa Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy;b Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, MI, ItalyView further author information
,
Jessica Avaglianob Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, MI, ItalyView further author information
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Andrea Cortesea Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy;b Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, MI, ItalyView further author information
,
Antonio Costanzoa Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy;b Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, MI, ItalyView further author information
&
Alessandra Narcisib Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, MI, ItalyView further author information
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Article: 2183729 | Received 03 Feb 2023, Accepted 16 Feb 2023, Published online: 27 Feb 2023

References

  • Barry K, Zancanaro P, Casseres R, et al. Concomitant atopic dermatitis and psoriasis - a retrospective review. J Dermatolog Treat. 2021;32(7):716–720.
  • Guttman-Yassky E, Krueger JG. Atopic dermatitis and psoriasis: two different immune diseases or one spectrum? Curr Opin Immunol. 2017;48:68–73.
  • Blauvelt A, Teixeira HD, Simpson EL, et al. Efficacy and safety of upadacitinib vs dupilumab in adults with moderate-to-severe atopic dermatitis: a randomized clinical trial. JAMA Dermatol. 2021;157(9):1047–1055.
  • Mease PJ, Lertratanakul A, Papp KA, et al. Upadacitinib in patients with psoriatic arthritis and inadequate response to biologics: 56-week data from the randomized controlled phase 3 SELECT-PsA 2 study. Rheumatol Ther. 2021;8(2):903–919.
  • He H, Bissonnette R, Wu J, et al. Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis. J Allergy Clin Immunol. 2021;147(1):199–212.
  • Brunner PM, Guttman-Yassky E, Leung DY. The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies. J Allergy Clin Immunol. 2017;139(4S):S65–S76.
  • Guttman-Yassky E, Krueger JG, Lebwohl MG. Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment. Exp Dermatol. 2018;27(4):409–417. Epub 2017 May 9. PMID: 28266782.
  • Barry K, Zancanaro P, Casseres R, et al. A retrospective review of dupilumab and psoriasis biologic combination therapy. J Dermatolog Treat. 2021;32(4):438–439.
  • Chiricozzi A, Gori N, Narcisi A, ACCURATE Group, et al. Effectiveness and safety of upadacitinib in the treatment of moderate-severe atopic dermatitis: a multicentric, prospective, real-world, cohort study. Drugs R D. 2022;22(3):245–252.
  • Gargiulo L, Ibba L, Cortese A, et al. Real-life effectiveness and safety of upadacitinib in adults and adolescents with moderate-to-severe atopic dermatitis: a single-center 16-week study. Dermatol Ther. 2023;13(2):651–660.

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