- BOEHM, T., FOLKMAN, J., BRODER, T. and O'REILLY, M. S., 1997, Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature, 390, 404-407.
- CHAPLIN, D. J. and DOUGHERTY, G. J., 1999, Tumour vasculature as a target for cancer therapy. British Journal of Cancer, 80 (Suppl. 1), 57-64.
- CHAPLIN, D. J., PETTIT, G. R. and HILL, S. A., 1999, Antivascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate. Anticancer Research, 19, 189-196.
- CHAPLIN, D. J., PETTIT, G. R., PARKINS, C. S. and HILL, S. A., 1996, Antivascular approaches to solid tumour therapy: evaluation of tubulin binding agents. British Journal of Cancer, 74 (Suppl. XXVII), S86-S88.
- CHING, L.-M., JOSEPH, W. R., CROSIER, K. E. and BAGULEY, B. C., 1994, Induction of tumor necrosis factor-a messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488). Cancer Research, 54, 870-872.
- CLIFFE, S., TAYLOR, M. L., RUTLAND, M., BAGULEY, B. C., HILL, R. P. and WILSON, W. R., 1994, Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid. International Journal of Radiation Oncology, Biology, Physics, 29, 373-377.
- DARK, G. G., HILL, S. A., PRISE, V. E., TOZER, G. M., PETTIT, G. R. and CHAPLIN, D. J., 1997, Combretastatin A-4, an agent that displays potent and selective toxicity toward tumour vasculature. Cancer Research, 57, 1829-1834.
- DENEKAMP, J. and HILL, S. A., 1991, Angiogenic attack as a therapeutic strategy for cancer. Radiotherapy and Oncology, 20, 103-112.
- DENEKAMP, J., HILL, S. A. and HOBSON, B., 1983, Vascular occlusion and tumour cell death. European Journal of Cancer, 19, 271-275.
- FOLKMAN, J., 1997, Antiangiogenic Therapy. In: Cancer: Principles & Practice of Oncology, edited by V. T. Jr Devita, S. Hellman and S. A. Rosenberg (Philadelphia, PA: Lippincott-Raven Publishers), pp. 3075-3085.
- GROSIOS, K., HOLWELL, S. E., McGOWN, A. T., PETTIT, G. R. and BlBBY, M. C., 1999, In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug. British Journal of Cancer, 81, 1318-1327.
- HORSMAN, M. R., CHRISTENSEN, K. L. and OVERGAARD, J., 1989, Hydralazine-induced enhancement of hyperthermic damage in a C3H mammary carcinoma in vino. International Journal of Hyperthermia, 5, 123-136.
- HORSMAN, M. R., EHRNROOTH, E., LADEKARL, M. and OVERGAARD, J., 1998, The efiect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors. International Journal of Radiation Oncology, Biology, Physics, 42, 895-898.
- HORSMAN, M. R., MURATA, R., BREIDAHL, T., NIELSEN, F. U., MAXWELL, R. J., STØDKILDE-JØRGENSEN, H. and OVERGAARD, J., 2000, Combretastatins: novel vascular targeting drugs for improving anti-cancer therapy. In: Angiogmesis: From Molecular to Integrative Pharmacology, edited by M. E. Maragoudakis (New York: Kluwer Academic/ Plenum Publishers), pp. 311-323.
- HORSMAN, M. R., SAMPSON, L. E., CHAPLIN, D. J. and OVERGAARD, J., 1996, The in vivo interaction between flavone acetic acid and hyperthermia. International Journal of Hyperthermia, 12, 779-789.
- IYER, S., CHAPLIN, D. J., ROSENTHAL, D. S., BOULARES, A. H., Ll, L.-Y. and SMULSON, M. E., 1998, Induction of apoptosis in proliferating human endothelial cells by the tumor-specific antiangiogenesis agent combretastatin A-4. Cancer Research, 58, 4510-4514.
- JOSEPH, W. R., CAO, Z., MOUNTJOY, K. G., MARSHALL, E. S., BAGULEY, B. C. and CHING, L.-M., 1999, Stimulation of tumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: a novel approach to cancer therapy. Cancer Research, 59, 633-638.
- LASH, C. J., LI, A. E., RUTLAND, M., BAGULEY, B. C., ZWI, L. J. and WILSON, W. R., 1998, Enhancement of the antitumour effects of the antivascular agent 5,6-dimethylxan-thenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs. British Journal of Cancer, 78, 439-445.
- LAWS, A. L., MATTHEW, A. M., DOUBLE, J. A. and BIBBY, M. C., 1995, Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid. British Journal of Cancer, 71, 1204-1209.
- Li, L., ROJIANI, A. and SIEMANN, D. W., 1998, Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy. International Journal of Radiation Oncology, Biology, Physics, 42, 899-903.
- MAXWELL, R. J., NIELSEN, F. U., BREIDAHL, T., STØDKILDE-JØRGENSEN, H. and HORSMAN, M. R., 1998, Effects of combretastatin on m urine tumours monitored by 31P MRS, 'H MRS and 'H MRI. International Journal of Radiation Oncology, Biology, Physics, 42, 891-894.
- OVERGAARD, J., 1980, Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo. International Journal of Radiation Oncology, Biology, Physics, 6, 1507-1517.
- PHILPOTT, M., JOSEPH, W. R., CROSIER, K. E., BAGULEY, B. C. and CHING, L.-M., 1997, Production of tumour necrosis factor-a by cultured human peripheral blood leucocytes in response to the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (NSC 640488). British Journal of Cancer, 76, 1586-1591.
- REWCASTLE, G. W., ATWELL, G. J., ZHUANG, L., BAGULEY, B. C. and DENNY, W. A., 1991, Potential antitumor agents 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids. Journal of Medicinal Chemistry, 34, 217-222.
- SAPIRSTEIN, L. A., 1958, Regional blood flow by fractional distribution of indicators. American Journal of Physiology, 193, 161-168.
- TOZER, G. M., PRISE, V. E., WILSON, J., LOCKE, R. J., VOJNOVIC, B., STRATFORD, M. R. L., DENNIS, M. F. and CHAPLIN, D. J., 1999, Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues. Cancer Research, 59, 1626-1634.
- WILSON, W. R., Li, A. E., COWAN, D. S. M. and SUM, B. G., 1998, Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. International Journal of Radiation Oncology, Biology, Physics, 42, 905-908.
- Zwi, L. J., BAGULEY, B. C., GAVIN, J. B. and WILSON, W. R., 1990, Necrosis in non-tumour tissues caused by flavone acetic acid and 5,6-dimethylxanthenone acetic acid. British Journal of Cancer, 62, 932-934.
Comparative effects of combretastatin A-4 disodium phosphate and 5,6-dimethylxanthenone-4-acetic acid on blood perfusion in a murine tumour and normal tissues
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