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Research Article

Adenovirus-mediated wild-type p53 gene expression radiosensitizes non-small cell lung cancer cells but not normal lung fibroblasts

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Pages 185-194 | Published online: 03 Jul 2009

References

  • BOUVET, M., ELLIS, L.M., NISHIZAKI, M., FUJIWARA, T Liu, W., BUCANA, C. D., FANG, B., LEE, J. J. and ROTH, J. A., 1998, Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expres-sion and inhibits angiogenesis in human colon cancer. Cancer Research, 58, 2288–2292.
  • BOVIATSIS, E. J., CHASE, M., WET, M. X., TAMIYA, T., HURFORD, R. K., JR., KOWALL, N. W., TEPPER, R. I., BREAKEFIELD, X. 0. and CHIOCCA, E. A., 1994, Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors. Human Gene Therapy, 5, 183–191.
  • EL-DEIRY, W. S., TOKINO, T VELCULESCU, V. E., LEVY, D. B., PARSONS, R., TRENT, J. M., UN, D., MERCER, W. E., KINZLER, K. W. and VOGELSTEIN, B., 1993, WAF1, a potential mediator of p53 tumor suppression. Cell, 75, 817–825.
  • FUJIWARA, T., GRIMM, E. A., MUKHOPADHYAY, T., ZHANG, W. W., OWEN-SCHAUB, L. B. and ROTH, J. A., 1994, Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Research, 54, 2287–2291.
  • GALLARDO, D., DRAZAN, K. E. and MCBRIDE, W. H., 1996, Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity. Cancer Research, 56, 4891–4893.
  • GRAHAM, F. L. and PREVEC, L., 1991, Manipulation of adeno-virus vectors. Method in Molecular Biology: Gene Transfer and Expression Protocol, edited by E. J. Murray (New Jersey: The Human Press, Inc.), pp.109–128
  • HARRIS, M. P., SUTJIPTO, S., WILLS, K. N., HANCOCK, W., C ORNELL, D., JOHNSON, D. E., GREGORY, R. J., SHEPARD, H. M. and MANE VAL, D. C., 1996, Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein. Cancer Gene Therapy, 3, 121–130.
  • KANEKO, S., HALLENBECK, P., KOTANI, T NAKABAYASHI, H., MCGARRITY, G., TAMAOKI, T., ANDERSON, W. F. and CHIANG, Y. L., 1995, Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression. Cancer Research, 55, 5283–5287.
  • LANG, F. F., YUNG, W. K., RAJU, U., LIBUNAO, F., TERRY, N. H. and T OFILON, P. J., 1998, Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene. journal of Neurosurgery, 89, 125–132.
  • LEVINE, A. J., 1997, p53, the cellular gatekeeper for growth and division. Cell, 88, 323–331.
  • Li, J. H., LAX, S. A., Kim, J., KLAMUT, H. and Liu, F. F., 1999, The effects of combining ionizing radiation and adenovi-ral p53 therapy in nasopharyngeal carcinoma. International Journal of Radiation, Oncology, Biology, Physics, 43, 607–616.
  • Liu, T. J., ZHANG, W. W., TAYLOR, D. L., ROTH, J. A., GOEPFERT, H. and CLAYMAN, G. L., 1994, Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus. Cancer Research, 54, 3662–3667.
  • MIYASHITA, T. and REED, J. C., 1995, Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell, 80, 293–299.
  • MuKH0EADHYAY, T. and ROTH, J. A., 1993, A codon 248 p53 mutation retains tumor suppressor function as shown by enhancement of tumor growth by antisense p53. Cancer Research, 53, 4362–4366.
  • NISHIO, M., KOSHIKAWA, T KUROISHI, T SUYAMA, M., UCHIDA, K., TAKAGI, Y., WASHIMI, 0., SUGIURA, T ARIYOSHI, Y., TAKAHASHI, T. and UEDA, R., 1996, Prognostic significance of abnormal p53 accumulation in primary, resected non-small-cell lung cancers. journal of Clinical Oncology, 14, 497–502.
  • NISHIZAKI, M., FUJIWARA, T TANIDA, T HiarrA, A., NISHIMORI, H TOKINO, T., NAKAMURA, Y., BOUVET, M., ROTH, J. A. and TANAKA, N., 1999, Recombinant adenovirus expressing wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect. Clinical Cancer Research, 5, 1015–1023.
  • O HSAKI, Y., TOYOSHIMA, E., FUJIUCHI, S., MATSUI, H HIRATA, S., MIYOKAWA, N., KUBO, Y. and KiKucHE K., 1996, bc1-2 and p53 protein expression in non-small cell lung cancers: correlation with survival time. Clinical Cancer Research, 2, 915–920.
  • PARKER, S. L., TONG, T., BOLDEN, S. and WINGO, P. A., 1997, Cancer statistics, 1997 [published erratum appears in CA Cancer J Clin 1997 Mar-Apr;47(2):68]. CAA Cancerjournal for Clinicians, 47, 5–27.
  • PIROLLO, K. F., H AO, Z., RAIT, A., JANG, Y. J., FEE, W. E., JR., RYAN, P., CHIANG, Y. and CHANG, E. H., 1997, p53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy. International journal of Cancer, 73, 367–370.
  • QUINLAN, D. C., DAVIDSON, A. G., SUMMERS, C. L., WARDEN, H. E. and DOSHI, H. M., 1992, Accumulation of p53 protein correlates with a poor prognosis in human lung cancer. Cancer Research, 52, 4828–4831.
  • RICCIONE, T CIRIELLI, C., WANG, X., PASSANITI, A. and CAPOGROSSI, M. C., 1998, Adenovirus-mediated wild-type p53 overexpression inhibits endothelial cell differen-tiation in vitro and angiogenesis in vivo. Gene Therapy, 5, 747–754.
  • ROTH, J. A., 1996, Modification of tumor suppressor gene expression and induction of apoptosis in non-small cell lung cancer (NSCLC) with an adenovirus vector expressing wildtype p53 and cisplatin. Human Gene Therapy, 7, 1013–1030.
  • SCHULER, M., ROCHLITZ, C., HOROWITZ, J. A., SCHLEGEL, J., PERRUCHOUD, A. P., Kommoss, F., BOLLIGER, C. T., KAUCZOR, H. U., DALQUEN, P., FRITZ, M. A., SWANSON, S., HERRMANN, R. and HUBER, C., 1998, A phase I study of adenovirus-mediated wild-type p53 gene transfer in patients with advanced non-small cell lung cancer. Human Gene Therapy, 9, 2075–2082.
  • SPITZ, F. R., NGUYEN, D., SKIBBER, J. M., CUSACK, J., ROTH, J. A. and CRISTIANO, R. J., 1996a, In vivo adeno-virus-mediated p53 tumor suppressor gene therapy for colorectal cancer. Anticancer Research, 16, 3415–3422.
  • SPITZ, F. R., NGUYEN, D., SKIBBER, J. M., MEYN, R. E., CRISTIANO, R. J. and ROTH, J. A., 1996b, Adenoviral-mediated wild-type p53 gene expression sensitizes colorec-tal cancer cells to ionizing radiation. Clinical Cancer Research, 2, 1665–1671.
  • SWISHER, S. G., ROTH, J. A., NEMUNAITIS, J., LAWRENCE, D. D., KEMP, B. L., CARRASCO, C. H., CONNORS, D. G., EL-NAGGAR, A. K., FOSSELLA, F., GLISSON, B. S., HONG, W. K., KHURI, F. R., KURIE, J. M., LEE, J. J., LEE, J. S., MACK, M., MERRITT, J. A., NGUYEN, D. M., NESBITT, J. C., PEREZ-SOLER, R. W., PISTERS, K. M., PUTNAM, J., J. B., RICHLI, W. R., SAWN, M., SCHRUMP, D. S., SHIN, D. M., SHULKIN, A., WALSH, G. L., WAIT, J., WEILL, D. and WAUGH, M. K. A., 1999, Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. Journal of National Cancer Institute, 91, 763–771.
  • TAKAHASHI, T NAU, M. M., CHIBA, I., BIRRER, M. J., ROSENBERG, R. K., VINOCOUR, M., LEVITT, M., PASS, H GAZDAR, A. F. and MINNA, J. D., 1989, p53: a frequent target for genetic abnormalities in lung cancer. Science, 246, 491–494.
  • TANG, D. C., JOHNSTON, S. A. and CARBONE, D. P., 1994, Butyrate-inducible and tumor-restricted gene expression by adenovirus vectors. Cancer Gene Therapy, 1, 15–20.
  • XU, H. J., ZHOU, Y., SEIGNE, J., PERNG, G. S., MIXON, M., ZHANG, C., LI, J., BENEDICT, W. F. and Hu, S. X., 1996, Enhanced tumor suppressor gene therapy via replication-deficient adenovirus vectors expressing an N-terminal truncated retinoblastoma protein. Cancer Research, 56, 2245–2249.
  • ZHANG, W. W., FANG, X., BRANCH, C. D., MAZUR, W., FRENCH, B. A. and ROTH, J. A., 1993, Generation and identification of recombinant adenovirus by liposome- mediated trans-fection and PCR analysis. Biotechniques, 15, 868–872.
  • ZHANG, W. W., FANG, X., MAZUR, W., FRENCH, B. A., GEORGES, R. N. and ROTH, J. A., 1994, High-efficiency gene transfer and high-level expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus. Cancer Gene Therapy, 1, 5–13.

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