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Research Article

Role of stress responses in human cell survival following exposure to ultraviolet C radiation.

Pages 365-374 | Published online: 03 Jul 2009

  • these pathways are likely to converge to promote cell
  • survival through a common eåector mechanism, or Akimoto, K., Takahashi, R., Moriya, S., Nishioka, N., Takayanagi, J., Kimura, K., Fukui, Y., Osada, S.-I.,
  • whether they elicit separate and complementary Mizuno, K., Hirai, S.-I., Kazlauskas, A. and Ohno, S.,
  • responses. Despite data on the phosphorylation of 1996, EGF or PDGF receptors activate atypical PKCl
  • potential substrates by PKCm in vitro (Dieterich et al. through phosphatidylinositol 3-kinase. EMBO Journal,
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  • For example, this isozyme has been linked to activa-and GF 109203X are equally potent inhibitors of MAPKAP kinase 1ß (Rsk-2) and p70 S6 kinase. FEBS
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  • et al. 1996) and has also been identi? ed as a key Bender, K., Blattner, C., Knebel, A., Iordanov, M.,
  • element of the signalling pathway leading to induc-Herrlich, P. and Rahmsdorf, H. J., 1997, UV-induced
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  • ine kinase inhibitor (PP1) resulted in enhanced sur-Wilkinson, S. E., 1994, Ro 32-0432, a selective and orally active inhibitor of protein kinase-C prevents T-cell
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