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International Journal of Radiation Biology Volume 77, 2001 - Issue 3
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Research Article

Collaborative exercise on the use of FISH chromosome painting for retrospective biodosimetry of Mayak nuclear-industrial personnel

M. Bauchinger GSF-National Research Center for Environment and Health, Institute of Radiobiology, Ingolstäder Landstr. 1, D-85764 Neuherberg, Germany
,
H. Braselmann GSF-National Research Center for Environment and Health, Institute of Radiobiology, Ingolstäder Landstr. 1, D-85764 Neuherberg, Germany
,
J. R. K. Savage MRC, Radiation and Genome Stability Unit, Harwell, Didcot OX11 0RD, UK
,
A. T. Natarajan MGC, University of Leiden, Medical Centre, Wassenaarseweg 72, Leiden 2333 AL, The Netherlands
,
G. I. Terzoudi NCSR-D, National Center for Scientific Research 'Demokritos', Institute of Nuclear Technology and Radiation Protection, Aghia Paraskevi Attikis, GR-15310 Athens, Greece
,
G. E. Pantelias NCSR-D, National Center for Scientific Research 'Demokritos', Institute of Nuclear Technology and Radiation Protection, Aghia Paraskevi Attikis, GR-15310 Athens, Greece
,
F. Darroudi GSF-National Research Center for Environment and Health, Institute of Radiobiology, Ingolstäder Landstr. 1, D-85764 Neuherberg, Germany
,
M. Figgitt MGC, University of Leiden, Medical Centre, Wassenaarseweg 72, Leiden 2333 AL, The Netherlands
,
C. S. Griffin MRC, Radiation and Genome Stability Unit, Harwell, Didcot OX11 0RD, UK
,
S. Knehr MRC, Radiation and Genome Stability Unit, Harwell, Didcot OX11 0RD, UK
,
N. D. Okladnikova GSF-National Research Center for Environment and Health, Institute of Radiobiology, Ingolstäder Landstr. 1, D-85764 Neuherberg, Germany
,
S. Santos FIBI, Public Health Ministry of the Russian Federation, Biophysics Institute Branch N1, Chelyabinsk-65, 456780, Ozyorsk, Russia
&
G. Snigiryova MRIDS, Moscow Research Institute of Diagnostic and Surgery, Department of Medicine, 117837, Moscow, Russia.
 show all
Pages 259-267 | Published online: 03 Jul 2009

  • BAUCHINGER, M., SALASSIDIS, K., BRASELMANN, H., VOZILOVA, A., PRESSL, S., STEPHAN, G., SNIGIRYOVA, G., KOZHEUROV, V. P. and AKLEYEV, A., 1998, FISH-based analysis of stable translocations in a Techa River population. International Journal of Radiation Biology, 73, 605-612.
  • CROW, E. L. and GARDNER, R. S., 1959, Confidence intervals for the expectation of a Poisson variable. Biometrika, 46, 441-453.
  • HANDE, M. P., BOEI, J. J. W. A., GRANATH, F. and NATARAJAN, A. T., 1996, Induction and persistence of cytogenetic damage in mouse splenocytes following whole-body X-irradiation analysed by fluorescence in situ hybridization. International Journal of Radiation Biology, 69, 437-446.
  • ICRP, 1974, Conversion Coefficients for Use in Radiological Protection Against External Radiation. Publication no. 74, Annals of ICRP, 26, 3-4.
  • KOSHURNIKOVA, N. A., BULDAKOV, L. A., BYSOGOLOV, G. D., BOLOTNIKOVA, M. G., KOMLEVA, N. S. and PESTERNIKOVA, V. S., 1994, Mortality from malignancies of the hematopoietic and lymphatic tissues among personnel of the first nuclear plant in the USSR. Science of the Total Environment, 142, 19-23.
  • LLOYD, D. C., MOQUET, J. E., ORAM, S. EDWARDS, A. A. and LUCAS, J. N., 1998, Accidental intake of tritiated water: a cytogenetic follow-up on translocation stability and dose reconstruction. International Journal of Radiation Biology, 73, 543-547.
  • LUCAS, J. N., AWA, A., STRAUME, T., POGGENSEE, M., KODAMA, M., OHTAKI, K., WEIER, D., PINKEL, D. GRAY, J. and LITTLEFIELD, G., 1992, Rapid translocation frequency analysis in humans decades after exposure to ionising radiation. International Journal of Radiation Biology, 62, 53-63.
  • LUCAS, J. N., CHEN, A. M. and SACHS, R. S., 1996a, Theoretical predictions on the equality of radiation-produced dicentrics and translocations detected by chromosome painting. International Journal of Radiation Biology, 69, 145-153.
  • LUCAS, J. N., DENG, W., MOORE, D., HILL, F., WADE, M., LEWIS, A., SAILES, F., KRAMER, C., HSIEH, A. and GALVAN, N., 1999, Background ionizing radiation plays a minor role in the production of chromosome translocations in a control population. International Journal of Radiation Biology, 75, 819-827.
  • LUCAS, J. N., HILL, F. S., BURK, C. E., COX, A. B. and STRAUME, T., 1996b, Stability of the translocation frequency following whole-body irradiation measured in rhesus monkeys. International Journal of Radiation Biology, 70, 309-317.
  • MATSUMOTO, K., RAMSEY, M. J., NELSON, D. O. and TUCKER, J. D., 1998, Persistence of radiation-induced translocations in human peripheral blood determined by chromosome painting. Radiation Research, 149, 602-613.
  • MERKLE, W., 1983, Statistical methods in regression and calibration analysis of chromosome aberration data. Radiation and Environmental Biophysics, 21, 217-233.
  • NAKAMURA, N., MIYAZAWA, C., SAWADA, S. AKIYAMA, M. and AWA, A. A., 1998, A close correlation between electron spin resonance (ESR) dosimetry from tooth enamel and cytogenetic dosimetry from lymphocytes of Hiroshima atomic-bomb survivors. International Journal of Radiation Biology, 73, 619-627.
  • NATARAJAN, A. T., SANTOS, S. J., DARROUDI, F., HADJIDIKOVA, V., VERMEULEN, S., CHATTERJEE, S., V/D BERG, M., GRIGOROVA, M., SAKAMOTO-HOJO, E. T., GRANATH, F., RAMALHO, A. T. and CURADO, M. P., 1998, 137Cs-induced chromosome aberrations analyzed by fluorescence in situ hybridization: eight years follow up of the Goiania radiation accident victims. Mutation Research, 400, 299-312.
  • SALASSIDIS, K., BRASELMANN, H., OKLADNIKOVA, N. D., PRESSL, S., STEPHAN, G., SNIGIRYOVA, G. and BAUCHINGER, M., 1998, Analysis of symmetrical translocations for retrospective biodosimetry in radiation workers of the Mayak nuclear-industrial complex (Southern Urals) using FISH chromosome painting. International Journal of Radiation Biology, 74, 431-439.
  • SALASSIDIS, K., GEORGIADOU-SCHUMACHER, V., BRASELMANN, H., MULLER, P., PETER, R. U. and BAUCHINGER, M., 1995, Chromosome painting in highly irradiated Chernobyl victims: A follow-up study to evaluate the stability of symmetrical translocations and the influence of clonal aberrations for retrospective dose estimation. International Journal of Radiation Biology, 68, 257-262.
  • SALASSIDIS, K., SCHMID, E., PETER, R. U., BRASELMANN, H. and BAUCHINGER, M., 1994, Dicentric and translocation analysis for retrospective dose estimation in humans exposed to ionising radiation during the Chernobyl nuclear power plant accident. Mutation Research, 311, 39-48.
  • SAVAGE, J. R. K. and SIMPSON, P. J., 1994a, On the scoring of FISH-'painted' chromosome exchange aberrations. Mutation Research, 307, 345-353.
  • SAVAGE, J. R. K. and SIMPSON, P. J., 1994b, FISH painting patterns resulting from complex exchanges. Mutation Research, 312, 51-60.
  • SAVAGE, J. R. K., PAPWORTH, D. G., BAUCHINGER, M., NATARAJAN, A. T., PANTELIAS, G. E., GRIFFIN, C. S., FIGGITT, M., KNEHR, S., BRASELMANN, H., DARROUDI, F., SANTOS, S. and TERZOUDI, G. E., 2000, Constructing a 2B calibration curve for retrospective dose reconstruction. Radiation Protection Dosimetry, 88, 69-76.
  • SIMPSON, P. J. and SAVAGE, J. R. K., 1996, Dose-response curves for simple and complex chromosome aberrations induced by X-rays and detected using fluorescence in situ hybridization. International Journal of Radiation Biology, 69, 429-436.
  • SNIGIRYOVA, G., BRASELMANN, H., SALASSIDIS, H., SHEVCHENKO, V. and BAUCHINGER, M. 1997, Retrospective biodosimetry of Chernobyl clean-up workers using chromosome painting and conventional chromosome analysis. International Journal of Radiation Biology, 71, 119-127.
  • SPRUILL, M. D., RAMSEY, M. J. SWIGER, R. R. NATH, J. and TUCKER, J. D., 1996, The persistence of aberrations in mice induced by gamma radiation as measured by chromosome painting. Mutation Research, 356, 135-145.
  • STRAUME, T., LANGLOIS, R. G., LUCAS, J., JENSEN, R. H., BIGBEE, W. L., RAMALHO, A. T. and BRANDAO-MELLO, C. E., 1991, Novel biodosimetry methods applied to victims of the Goiania accident. Health Physics, 60, 71-76.
  • TUCKER, J. D., BRENEMAN, J. W. BRINER, J., EVELETH, G. G., LANGLOIS, R. G. and MOORE, D. H., II, 1997a, The persistence of radiation-induced translocations in rat peripheral blood determined by chromosome painting. Environmental Molecular Mutagenesis, 30, 264-272.
  • TUCKER, J. D., TAWN, E. J., HOLDSWORTH, D., MORRIS, D., LANGLOIS, R., RAMSEY, M. J., KATO, P., BOICE, J. D., JR, TARONE, R. E. and JENSEN, R. H., 1997b, Biological dosimetry of radiation workers at the Sellafield nuclear facility. Radiation Research, 148, 216-226.
  • XIAO, Y., DARROUDI, F., GRIGOROVA, M. and NATARAJAN, A. T., 1999, Induction and persistence of chromosomal exchanges in mouse bone marrow cells following wholebody exposure to X-rays. International Journal of Radiation Biology, 75, 1119-1128.

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