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Research Article

Analysis of radiation-induced chromosomal aberrations using telomeric and centromeric PNA probes

Pages 163-167 | Published online: 03 Jul 2009

  • BOEI, J. J. W. A. and NATARAJAN, A. T., 1998, Combined use of chromosome painting and telomere detection to analyse radiation induced chromosomal aberrations in mouse splenocytes. International Journal of Radiation Biology, 73, 125-133.
  • BOEI, J. J. W. A., VERMEULEN, S., FOMINA, J. and NATARAJAN, A. T., 1998, Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe. International Journal of Radiation Biology, 73, 599-603.
  • BOEI, J. J. W. A., VERMEULEN, S. and NATARAJAN, A. T., 1996, Detection of chromosomal aberrations by fluorescence in situ hybridization in the first three postirradiation divisions of human lymphocytes. Mutation Research, 349, 127-135.
  • DE LANGE, T., 1992, Human telomeres are attached to the nuclear matrix. EMBO Journal, 11, 717-724.
  • FOMINA, J., DARROUDI, F., BOEI, J. J. W. A. and NATARAJAN, A. T., 1999, Discrimination between complete and incomplete chromosome exchanges in X-irradiated human lymphocytes using FISH with pan-centromeric and chromosome specific DNA probes in combination with telomeric PNA probe. International Journal of Radiation Biology (in press).
  • MOYZIS, R. K., BUCKINGHAM, J. M., CRAM, L. S., DANI, M., DEAVEN, L. L., JONES, M. D., MEYNE, J., RATLIFF, R. L. and Wu, J. R., 1988, A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proceedings of the National Academy of Sciences of the United States of America, 85, 6622-6626.
  • WU, H., GEORGE, K. and YANG, T. C., 1998, Estimate of true incomplete exchanges using fluorescence in situ hybridization with telomere probes. International Journal of Radiation Biology, 73, 521-527.

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