37
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Investigation of G2-phase chromosomal radiosensitivity in hereditary non-polyposis colorectal cancer cells

, , , &
Pages 773-780 | Published online: 03 Jul 2009

  • BENDER, M. A., RARY, J. M. and KALE, R. P., 1985, G2 chromosomal radiosensitivity in ataxia telangiectasia lymphocytes. Mutation Research, 152, 39-47.
  • BENDER, M. A., VIOLA, M. V., FIORE, J., THOMPSON, M. H. and LEONARD, R. C., 1988, Normal G2 chromosomal radiosensitivity and cell survival in the cancer family syndrome. Cancer Research, 48, 2579-2584.
  • BIGELOW, S. B., RARY, J. M. and BENDER, M. A., 1979, G2 chromosomal radiosensitivity in Fanconi's anemia. Mutation Research, 63, 189-199.
  • BODMER, W., BISHOP, T. and KARRAN, P., 1994, Genetic steps in colorectal cancer. Nature Genetics, 6, 217-219.
  • BRONNER, C. E., BAKER, S. M., MORRISON, P. T., WARREN, G., SMITH, L. G., LESCOE, M. K., KANE, M., EARABIND, C., LIPFORD, J. and LINDBLOM, A., 1994, Mutation in the DNA mismatch repair gene homologue hMLHl is associated with hereditary non-polyposis colon cancer. Nature, 368, 258-261.
  • CHEN, W. and JINKS-ROBERTSON, S., 1998, Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast. Molecular and Cellular Biology, 18, 6525-6537.
  • DARROUDI, F., VYAS, R. C., VERMEULEN, S. and NATARAJAN, A. T., 1995, G2 radiosensitivity of cells derived from cancer-prone individuals. Mutation Research, 328, 83-90.
  • DATTA, A., ADJIRI, A., NEW, L., CROUSE, G. F. and JINKSROBERTSON, S., 1996, Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces ceresisiae. Molecular and Cellular Biology, 16, 1085-1093.
  • DE ANGELIS, P. M., CLAUSEN, O. P., SCHJOLBERG, A. and STOKKE, T., 1999, Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes. British Journal of Cancer, 80, 526-535.
  • DE WIND, N., DEKKER, M., CLAIJ, N., JANSEN, L., VANKLINK, Y., RADMAN, M., RIGGINS, G., VAN DER VALK, M., VANY WOUT, K. and TE RIELE, H., 1999, HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nature Genetics, 23, 359-362.
  • DUCKWORTH-RYSIECKI, G. and TAYLOR, A. M., 1985, Effects of ionizing radiation on cells from Fanconi's anemia patients. Cancer Research, 45, 416-420.
  • EVANS, E., SUGAWARA, N., HABER, J. E. and ALANI, E., 2000, The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in moo. Molecular CeU, 5, 789-799.
  • FISHEL, R., LESCOE, M. K., RAO, M. R., COPELAND, N. G., JENKINS, N. A., GARBER, J., KANE, M. and KOLODNER, R., 1993, The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. CeU, 75, 1027-1038.
  • HEMMINKI, A., PELTOMAKI, P., MECKLIN, J. P., JARVINEN, H., SALOVAARA, R., NYSTROM-LAHTI, M., DE LA CHAPELLE, A. and AALTONEN, L. A., 1994, Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nature Genetics, 8, 405-410.
  • HENDERSON, G. and SIMONS, J. P., 1997, Processing of DNA prior to illegitimate recombination in mouse cells. Molecular and Cellular Biology, 17, 3779-3785.
  • INBAR, O. and KUPIEC, M., 1999, Homology search and choice of homologous partner during mitotic recombination. Molecular and Cellular Biology, 19, 4134-4142.
  • KOLODNER, R., 1996, Biochemistry and genetics of eukaryotic mismatch repair. Genes and Development, 10, 1433-1442.
  • KUHN, E. M., 1980, Effects of X-irradiation in Gl and G2 on Bloom's Syndrome and normal chromosomes. Human Genetics, 54, 335-341.
  • LEACH, F. S., NICOLAIDES, N. C., PAPADOPOULOS, N., LIU, B., JEN, J., PARSONS, R., PELTOMAKI, P., SISTONEN, P., AALTONEN, L. A. and NYSTROM-LAHTI, M., 1993, Mutations of a mutS homologue in hereditary nonpolyposis colorectal cancer. Cell, 75, 1215-1225.
  • LENGAUER, C., KINZLER, K. W. and VOGELSTEIN, B., 1997, Genetic instability in colorectal cancers. Nature, 386, 623-627.
  • LIU, B., PARSONS, R., PAPADOPOULOS, N., NICOLAIDES, N. C., LYNCH, H. T., WATSON, P., JASS, J. R., DUNLOP, M., WYLLIE, A., PELTOMAKI, P., DE LA CHAPELLE, A., HAMILTON, S. R., VOGELSTEIN, B. and KINZLER, K. W., 1996, Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nature Medicine, 2, 169-174.
  • MARSISCHKY, G. T., FILOSI, N., KANE, M. F. and KOLODNER, R., 1996, Redundancy of Saccharamyces cerninae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes and Development, 10, 407-420.
  • MIYAZAKI, M., FURUYA, T., SHIRAKI, A., SATO, T., OGA, A. and SASAKI, K., 1999, The relationship of DNA ploidy to chromosomal instability in primary human colorectal cancers. Cancer Research, 59, 5283-5285.
  • NATARAJAN, A. T., VOSSEN, J. M. J. J. and VAN WEELSIPMAN, M. H., 1989, Aplastic anemia and Fanconi anemia: response of lymphocytes to X-rays and mitomycin C. In Fanconi anaemia, edited by T. M. SchroederKurth and A. D. Auerbach (Berlin: Spriger-Verlag), pp. 100-104.
  • NICHOLSON, A., HENDRIX, M., JINKS-ROBERTSON, S. and GROUSE, G. F., 2000, Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes. Genetics, 154, 133-146.
  • NICOLAIDES, N. C., PAPADOPOULOS, N., LIU, B., WEI, Y. F., CARTER, K. C., RUBEN, S. M., ROSEN, C. A., HASELTINE, W. A., FLEISCHMANN, R. D., FRASER, C. M, ADAMS, M. D., VENTER, J. C., DUNLOP, M. G., HAMILTON, S. R., PETERSEN, G. M., DE LA CHAPELLE, A., VOGELSTEIN, B. and KINZLER, K. W., 1994, Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature, 371, 75-80.
  • PALITTI, F., PICHIERRI, P., FRANCHITTO, A., PROIETTI DE SANTIS, L. and MOSESSO, P., 1999, Chromosome radiosensitivity in human G2 lymphocytes and cell-cycle progression. International Journal of Radiation Biology, 75, 621-627.
  • PAPADOPOULOS, N., NICOLAIDES, N. C., LIU, B., PARSONS, R., LENGAUER, C., PALOMBO, F., D'ARRIGO, A., MARKOWITZ, S., WILLSON, J. K., KINZLER, K. W., JIRICNY, J. and VOGELSTEIN, B., 1995, Mutations of GTBP in genetically unstable cells. Science, 268, 1915-1917.
  • PARSHAD, R., PRICE, F. M., PIROLLO, K. F., CHANG, E. H. and SANFORD, K. K., 1993, Cytogenetic response to G2-phase X irradiation in relation to DNA repair and radiosensitivity in a cancer-prone family with Li-Fraumeni syndrome. Radiation Research, 136, 236-240.
  • PARSHAD, R., SANFORD, K. K. and JONES, G. M., 1983, Chromarid damage after G2 phase x-irradiation of cells from cancer-prone individuals implicates deficiency in DNA repair. Proceedings of the National Academy of Sciences of the United States of America, 80, 5612-5616.
  • PARSHAD, R., SANFORD, K. K., JONES, G. M. and TARONE, R. E., 1985, G2 chromosomal radiosensitivity of ataxiatelangiectasia heterozygotes. Cancer Genetics and Cytogenetics, 14, 163-168.
  • PETERS, L. J., 1990a, Regaud lecture: inherent radiosensitivity of tumour and normal tissue cells as a predictor of human tumour response. Radiotherapy and Oncology, 17, 177-190.
  • PETERS, L. J., 1990b, Significance of genetic variability in radiosensitivity in clinical radiotherapy. Journal of the Japanese Society of Therapy Radiology and Oncology, 2,247-253.
  • RISINGER, J. I., UMAR, A., BOYD, J., BERCHUCK, A., KUNKEL, T. A. and BARRETT, J. C., 1996, Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair. Nature Genetics, 14, 102-105.
  • SANFORD, K. K., PARSHAD, R., GANTT, R., TARONE, R. E., JONES, G. M. and PRICE, F. M., 1989, Factors affecting and significance of G2 chromatin radiosensitivity in predisposition to cancer. International Journal of Radiation Biology, 55, 963-981.
  • SANFORD, K. K., PARSHAD, R., PRICE, F. M., JONES, G. M., TARONE, R. E., EIERMAN, L., HALE, P. and WALDMANN, T. A., 1990, Enhanced chromatid damage in blood lymphocytes after G2 phase x irradiation, a marker of the ataxia-telangiectasia gene. Journal of the National Cancer Institute, 82, 1050-1054.
  • SCOTT, D., BARBER, J. B., LEVINE, E. L., BURRILL, W. and ROBERTS, S. A., 1998, Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposition? British Journal of Cancer, 77, 614-620.
  • SCOTT, D., BARBER, J. B., SPREADBOROUGH, A. R., BURRILL, W. and ROBERTS, S. A., 1999, Increased chromosomal radiosensitivity in breast cancer patients: a comparison of two assays. International Journal of Radiation Biology, 75, 1-10.
  • SCOTT, D., SPREADBOROUGH, A. R., JONES, L. A., ROBERTS, S. A. and MOORE, C. J., 1996, Chromosomal radiosensitivity in G2-phase lymphocytes as an indicator of cancer predisposition. Radiation Research, 145, 3-16.
  • SHCHERBAKOVA, P. V. and KUNKEL, T. A., 1999, Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for m1h1 mutations. Molecular and Cellular Biology, 19, 3177-3183.
  • TAYLOR, A. M., HARNDEN, D. G., ARLETT, C. F., HARCOURT, S. A., LEHMANN, A. R., STEVENS, S. and BRIDGES, B. A., 1975, Ataxia-telangiectasia: a human mutation with abnormal radiation sensitivity. Nature, 258, 427-429.
  • TAYLOR, A. M. R., 1983, The effect of radiation on the chromosomes of patients with an unusual cancer susceptibility. In Radiation induced chromosome damage in man edited by T. Ishihar and M. Sasaki (New York: Alan R. Liss), pp. 167-199.
  • TICE, R., RARY, J. M. and BENDER, M. A., 1978, An investigation of DNA repair potential in Bloom's syndrome. Journal of Supramolecular Structure, 2 (Suppl.), 82.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.