Advanced search
Publication Cover
International Journal of Radiation Biology Volume 77, 2001 - Issue 7
Submit an article Journal homepage
27
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Relationship between radiation-induced aberrations in individual chromosomes and their DNA content: effects of interaction distance

H. Wu Radiation Biophysics Laboratory and Kelsey-Seybold Clinic, NASA Johnson Space Center, Mail Code SD23, Houston, TX 77058, USA.
,
M. Durante Department of Physics, University of Naples, Naples, Italy.
&
J. N. Lucas Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94550, USA.
Pages 781-786 | Published online: 03 Jul 2009

  • BARQUINERO, J. F., KNEHR, S., BRASELMANN, H., FIGEL, M. and BAUCHINGER, M., 1998, DNA-proportional distribution of radiation-induced chromosome aberrations analyzed by fluorescence in situ hybridization painting of all chromosomes of a human female karyotype. International Journal of Radiation biology, 74, 315-323.
  • BRENNER, D. J. and SACHS, R. K., 1994, Commentary: chromosomal 'fingerprints' of prior exposure to densely ionizing radiation. Radiation Research, 140, 134-142.
  • CIGARRAN, S., BARRIOS, L., BARQUINERO, J. F., CABALLIN, M. R., RIBAS, M. and EGOZCUE, J., 1998, Relationship between the DNA content of human chromosomes and their involvement in radiation-induced structural aberrations, analysed by painting. International Journal of Radiation biology, 74, 449-455.
  • CORNFORTH, M. N., 2000, Peering into a kettle of FISH. Abstract presented at the 47th Annual Meeting of the Radiation Research Society, abstract 58.
  • DURANTE, M., GEORGE, K., Wu, H. and YANG, T. C., 1996, Rejoining and misrejoining of radiation-induced chromatin breaks. I. Experiments in human lymphocytes. Radiation Research, 145, 274-280.
  • EDWARDS, A. A., MOISEENKO, V. V. and NIKJOO, H., 1994, Modelling of DNA breaks and the formation of chromosome aberrations. International Journal of Radiation Biology, 66, 633-637.
  • FINNON, P, LLOYD, D. C. and EDWARDS, A. A., 1995, Fluorescence in situ hybridization detection of chromosomal aberrations in human lymphocytes: applicability to biological dosimetry. International Journal of Radiation Biology, 68, 429-435.
  • JOHNSON, K. L., BRENNER, D. J., NATH, J., TUCKER, J. D. and GEARD, C. R., 1999, Radiation-induced breakpoint misrejoining in human chromosomes: random or non-random. International Journal of Radiation Biology, 75, 131-141.
  • KELLERER, A. M. and Rossi, H. H., 1978, A generalized formulation of dual radiation action. Radiation Research, 75, 471-488.
  • KNEHR, S., ZITZELSBERGER, H., BRASELMANN, H., NAHRSTEDT, U. and BAUCHINGER, M., 1996, Chromosome analysis by fluorescence in situ hybridization: further indications for a non-DNA-proportional involvement of single chromosomes in radiation-induced structural aberrations. International Journal of Radiation Biology, 70, 385-392.
  • LUCAS, J. N., AWA, A., STRAUME, T., POGGENSEE, M, KODAMA, Y., NAKAND, M., OHTAKI, K., WEIER, H.-LJ., PINKEL, D., GRAY, J. and LITTLEFIELD, G., 1992, Rapid translocation frequency analysis in human decades after exposure to ionizing radiation. International Journal of Radiation Biology, 62, 53-63.
  • MANUELIDIS, L., 1985, Individual interphase chromosome domains revealed by in situ hybridization. Human Genetics, 71, 288-293.
  • NAKAND, M., NAKASHIMA, E., PAWEL, D. J., KODAMA, Y. and AWA, A., 1993, Frequency of reciprocal translocations and dicentrics induced in human blood lymphocytes by X-irradiation as determined by fluorescence in situ hybridization. International Journal of Radiation Biology, 64, 565569.
  • OSTASHEVSKY, J. Y., 2000, High-order structure of interphase chromosomes and radiation-induced chromosomal exchange aberrations. International Journal of Radiation Biology, 76, 1179-1187.
  • SACHS, R. K., AWA, A., KODAMA, Y., NAKAND, M., OHTAKI, K.and LUCAS, J. N., 1993, Ratios of radiation-produced chromosome aberrations as indicators of large-scale DNA geometry during interphase. Radiation Research, 133, 345-350.
  • SACHS, R. K., CHEN, A. M. and BRENNER, D. J., 1997, Review: proximity effects in the production of chromosome aberrations by ionizing radiation. International Journal of Radiation Biology, 71, 1-19.
  • SACHS, R. K., ROGOFF, A., CHEN, A. M., SIMPSON, P. J., SAVAGE, J. R. K., HANFELDT, P. and HLATKY, L. R., 2000, Underprediction of visibly complex chromosome aberrations by a recombinational-repair ('one-hit') model. International Journal of Radiation Biology, 76, 129-148.
  • SAVAGE, J. R. K. and PAPWORTH, D. G., 1973, The relationship of radiation-induced dicentric yield to chromosome arm number. Mutation Research, 19, 139-143.
  • SAVAGE, J. R. K. and PAPWORTH, D. G., 1982, Frequency and distribution studies of asymmetrical versus symmetrical chromosome aberrations. Mutation Research, 95, 7-18.
  • VAN DEKKEN, H. D., PINKEL, D., MULLIKIN, J., TRASK, B., VAN DEN ENG, G. and GRAY, J., 1989, Three-dimensional analysis of the organization of human chromosome domains in human and human hamster hybrid interphase nuclei. Journal of Cell Science, 94, 299-306.
  • Wu, H., 2001, Radiation-induced inter/intra-chromosomal exchange probabilities and their dependence on DNA content of the chromosome. In Symposium Proceedings 'Models for Evaluation of Radiation Risk Issues', Radiation Research (accepted).
  • Wu, H., GEORGE, K., KAWATA, T., WILLINGHAM, V. and CUCINDTTA, F. A., 2001, Comparison of F ratios generated from interphase and metaphase chromosome damage induced by high doses of low-and high-LET radiation. Radiation Research, 155, 57-62.
  • Wu, H., SACHS, R. K. and YANG, T. C., 1998, Radiationinduced total-deletion mutations in the human hprt gene: a biophysical model based on random walk interphase chromatin geometry. International Journal of Radiation Biology, 73, 149-156.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.