58
Views
17
CrossRef citations to date
0
Altmetric
Research Article

Evidence of genetic instability in 3 Gy X-ray-induced mouse leukaemias and 3 Gy X-irradiated haemopoietic stem cells

, , , , &
Pages 1023-1031 | Published online: 03 Jul 2009

  • BAN, N., KAI, M. and KUSAMA, T., 1997, Chromosome aberrations in bone marrow cells of C3H/He mice at an early stage after whole-body irradiation. Journal of Radiation Research, 38, 219-231.
  • BLOOM, A. D., NERIISHI, S., KAMADA, N., ISEKI, T. and KEEHN, R. J., 1996, Cytogenetic investigation of survivors of the atomic bombings of Hiroshima and Nagasaki. Lancet, 2, 672-674.
  • BOUFFLER, S. D., MEIJNE, E. I. M., HUISKAMP, R. and Cox, R., 1996a, Chromosomal abnormalities in neutron-induced acute myeloid leukaemias in CBA/H mice. Radiation Research, 146, 349-352.
  • BOUFFLER, S. D., BRECKON, G. and Cox, R., 1996b, Chromosomal mechanisms in murine radiation acute myeloid leukaemogenesis. Carcinogenesis, 17, 655-659.
  • BOUFFLER, S. D., MEIJNE, E. I. M., MORRIS, D. J. and PAPWORTH, D., 1997, Chromosome 2 hypersensitivity and clonal development in murine radiation acute myeloid leukaemia. International Journal of Radiation Biology, 72,181-189.
  • BOULTON, E., CLEARY, H., PAPWORTH, D. and PLUMB, M., 2001, Susceptibility to radiation-induced leukaemia/lymphoma is genetically separable from sensitivity to radiationinduced genomic instability. International Journal of Radiation Biology, 77, 21-29.
  • BRECKON, G., PAPWORTH, D. and Cox, R., 1991, Murine radiation myeloid leukaemogenesis: a possible role for radiation-sensitive sites on chromosome 2. Genes Chromosomes and Cancer, 3, 367-375.
  • CLEARY, H. J., WRIGHT, E. and PLUMB, M., 1999, Specificity of loss of heterozygosity in radiation-induced mouse myeloid and lymphoid leukaemias. International Journal of Radiation Biology, 75, 1223-1230.
  • DEVI, P. U. and HOSSAIN, M., 2000, Induction of chromosomal instability in mouse haemopoietic cells by fetal irradiation. Mutation Research, 456, 33-37.
  • DI MAJO, V., COPPOLA, M., REBESSI, S., SARAN, A., PAZZ\GLIA, S., PARISET, L. and COVELLI, V., 1996, The influence of sex on life shortening and tumour induction in CBA/Cne mice exposed to X-rays or fission neutrons. Radiation Research, 146, 81-87.
  • HAYATA, I., SEKI, M., YOSHIDA, K., HIRASHIMA, K., SADO, T., YAMAGIWA, J. and ISHIHARA, T., 1983, Chromosomal aberrations observed in 52 mouse myeloid leukaemias. Cancer Research, 43, 367-373.
  • GRAHAM, G. J. and WRIGHT, E. G., 1997, Haemopoietic stem cells: their heterogeneity and regulation. International Journal of Experimental Pathology, 78, 197-218.
  • GREAVES, M., 1993, Stem cell origins of leukaemia and curability. British Journal of Cancer, 67, 413-423.
  • GREAVES, M., 1997, Stem cells, haemopoiesis, and leukaemia. In Cellular and Molecular Biology of Cancer, third edition, edited by L. M. Frank and N. M. Teich (Oxford, U.K.: Oxford University Press), pp. 251-263.
  • KADHIM, M. C., MACDONALD, D. A., GOODHEAD, D. T., LORIMORE, S. A., MARSDEN, S. J. and WRIGHT, E. G., 1992, Transmission of chromosomal instability after plutonium alpha-particle irradiation. Nature, 355, 738-740.
  • KADHIM, M. A., LORIMORE, S. A., HEPBURN, M. D., GOODHEAD, D. T., BUCKLE, V. J. and WRIGHT, E. G., 1994, Alphaparticle-induced chromosomal instability in human bone marrow cells. Lancet, 344, 87-988.
  • KADHIM, M. A., POCOCK, D. A., LORIMORE, S. A. and WRIGHT, E. G., 1999, An improved micro method for obtaining chromosome preparations from individual haemopoietic colonies. British Journal of Haemotology, 105, 673-675.
  • KAMADA, N., KURAMOTO, A., KATSUKI, T. and HINUMA, Y., 1979, Chromosome aberrations in B lymphocytes of atomic bomb survivors. Blood, 53, 1140-1146.
  • LENGAUER, C., KINZLER, K. W. and VOGELSTEIN, B., 1998, Genetic instabilities in human cancers. Nature, 396, 643-649.
  • LITTLE, J. B., 1998, Radiation-induced genomic instability. International Journal of Radiation Biology, 74, 663-671.
  • MAJOR, I. R., 1979, Induction of myeloid leukaemia by wholebody single exposure of CBA male mice to X-rays. British Journal of Cancer, 40, 903-913.
  • MATSUMOTO, Y., KOSUGI, S., SHINBO, T., CHOU, D., OHASHI, M., WAKABAYASHI, Y., SAKAI, K., OKUMOTO, M., MORI, N., AIZAWA, S., NIWA, O. and KOMINAMI, R., 1998, Allelic loss analysis of ?-ray-induced mouse thymic lymphomas: two candidate tumour suppressor gene loci on chromosomes 12 and 16. Oneogme, 16, 2747-2754.
  • MCC ULLOCH, E. A., 1983, Stem cells in normal and leukemic hemopoiesis. Blood, 62, 1-13.
  • MOLE, R. H., 1986, Radiation-induced acute myeloid leukaemia in the mouse: experimental observations in vivo with implications for hypotheses about the basis of carcinogenesis. Leukaemia Research, 10, 859-865.
  • MORGAN, W. F., DAY, J. P., KAPLAN, M. I., McGHEE, E. M. and LlMOLI, C. L., 1996, Genomic instability induced by ionizing radiation. Radiation Research, 146, 247-258.
  • NAKANISHI, M., TANAKA, K., SHINTANI, T., TAKAHASHI, T. and KAMADA, N., 1999, Chromosomal instability in acute myelocytic leukaemia and myelodysplastic syndrome patients among atomic bomb survivors. Journal of Radiation Research, 40, 159-167.
  • PHILIP, P. and PEQERSEN-BJERGAARD, J., 1988, Cytogenetic, clinical and cytologie characteristics of radiotherapyrelated leukaemias. Cancer Genetics and Cytogenetics, 31, 227-236.
  • PLUMB, M., HARPER, K., MACDONALD, D., FENNELLY, J., LORIMORE, S. and WRIGHT, E., 1997, Ongoing Y chromosome instability defines sub-clonal variants in radiationinduced leukaemias in the mouse. International Journal of Radiation Biology, 72, 1-9.
  • PONNAIYA, B., CORNFORTH, M. N. and ULLRICH, R. L., 1997, Radiation-induced chromosomal instability in BALB/c and C57BL/6 mice: the difference is as clear as black and white. Radiation Research, 147, 121-125.
  • PRAGNELL, I. B., WRIGHT, E. G., LORIMORE, S. A., ADAM, J., ROSENDAAL, M., DELAMARTER, J. F., FRESHNEY, M., ECKMANN, L., SPROUL, A. and WILKIE, N., 1988, The eflect of stem cell proliferation regulators demonstrated with an in vitro assay. Blood, 72, 196-201.
  • PRESTON, D. L., KUSUMI, S., TOMONAGA, M., IZUMI, S., RON, E., KURAMOTO, A., KAMADA, N., DOHY, H., MTASUI, T., NONAKA, H., THOMPSON, D. E., SODA, M. and MABUCHI, K., 1994, Cancer incidence in atomic bomb survivors. Part III. Leukaemia, lymphoma and multiple myeloma, 1950-1987. Radiation Research, 137, S68-S97.
  • QUESNIAUX, V. F. J., GRAHAM, G. J., PRAGNELL, I., DONALDSON, D., WOLPE, S. W., ISCOVE, N. N. and FAGG, B., 1993, Use of 5-fluorouracil to analyze the effect of macrophage inflammatory protein-1 a on long term reconstituting stem cells in vivo. Blood, 81, 1497-1504.
  • RASKIND, W. H., STEINMANN, L. and NAJFELD, V., 1998, Clonal development of myeloproliferative disorders: clues to hematopoietic differentiation and multistep pathogenesis of cancer. Leukemia, 12, 108-116.
  • RITHIDECH, K. N., BOND, V. P., CRONKITE, E. P. and THOMPSON, M. H., 1993, A specific chromosome deletion in murine leukaemic cells induced by radiation with different qualities. Experimental Haematology, 21, 427-431.
  • RITHIDECH, K. N., BOND, V. P., CRONKITE, E. P., THOMPSON, M. H. and BULLIS, J. E., 1995, Hypermutability of mouse chromosome 2 during the development of X-ray-induced murine myeloid leukaemia. Proceeds of the National Academy of Sciences USA, 92, 1152-1156.
  • SANTOS, J., PEREZ DE CASTRO, I., HERRANZ, M., PELUCER, A. and FERNANDEZ-PlQUERAS, J., 1996, Allelic loss on chromosome 4 suggest the existence of a candidate tumor suppressor gene region of about 0.6 cM in ?-radiationinduced mouse primary thymic lymphomas. Oncogene, 12, 669-676.
  • SHIMADA, Y., NISHIMURA, M., KAKINUMA, S., OKUMOTO, M., SHIROSHI, T., CLIFTON, K. H. and WAKANA, S., 2000, Radiation-associated loss of heterozygosity at the Znfnlal (Ikaros] locus on chromosome 11 in murine thymic lymphomas. Radiation Research, 154, 293-300.
  • TANAKA, K., KAMADA, N., OKHITA, T. and KURAMOTO, A., 1983, Nonrandom distribution of chromosome breaks in lymphocytes of atomic bomb survivors. Journal of Radiation Research, 24, 291-304.
  • TRAKHTENBROT, L., KRAUTHGAMER, R., RESNITZKY, P. and HARAN-GHERA, N., 1988, Deletion of chromosome 2 is an early event in the development of radiation-induced myeloid leukaemia in SJL/J mice. Leukaemia, 2, 545-550.
  • VAN LOM, K., HAGEMEIJER, A., VANDEKERCHOVE, F., SMIT, E. M. E. and LOWENBERG, B., 1996, Cytogenetic clonality analysis: typical patterns in myelodysplastic syndrome and acute myeloid leukaemia. British Journal of Haematology, 93, 594-600.
  • VESSEY, C. J., NORBURY, C. J. and HICKSON, I. D., 1999, Genetic disorders associated with cancer predisposition and genomic instability. Progress in Nucleic Acid Molecular Biology, 63, 189-221.
  • WATSON, G. E., LORIMORE, S. A. and WRIGHT, E. G., 1996, Long-term in vivo transmission of a-particle-induced chromosomal instability in murine haemopoietic cells. International Journal of Radiation Biology, 69, 175-182.
  • WATSON, G. E., LORMIRE, S. A., CLUTTON, S. M., KAEHIM, M. A. and WRIGHT, E. G., 1997, Genetic factors influencing a-particle-induced chromosomal instability. International Journal of Radiation Biology, 71, 497-503.
  • WATSON, G. E., POCOCK, D. A., PAPWORTH, D., LORIMORE, S. A. and WRIGHT, E. G., 2001, In vivo chromosomal instability and transmissable aberrations in the progeny of haemopoietic stem cells induced by high- and lowLET radiations. International Journal of Radiation Biology, 77, 409-417.
  • WRIGHT, E. G. and LORD, B. I., 1992, Haemopoietic tissue. BaMeTe1S Clinical Haematology, 5, 499-507.
  • WRIGHT, E. G., 1998, Radiation-induced genomic instability in haemopoietic cells. International Journal of Radiation Biology, 74, 681-687.
  • XIAO, Y., DARROUDI, M. and NATARAJAN, A. T., 1999, Induction and persistence of chromosomal exchanges in mouse bone marrow cells following whole-body exposure to X-rays. International Journal of Radiation Biology, 75, 1119-1128.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.